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Items: 1 to 50 of 501

1.

Does the separation from marital partners of Syrian refugees with a residence permit in Germany have an impact on their quality of life?

Georgiadou E, Schmitt GM, Erim Y.

J Psychosom Res. 2020 Jan 16;130:109936. doi: 10.1016/j.jpsychores.2020.109936. [Epub ahead of print]

PMID:
31972478
2.

Pediatric Safety of Polysorbates in Drug Formulations.

Kriegel C, Festag M, Kishore RSK, Roethlisberger D, Schmitt G.

Children (Basel). 2019 Dec 20;7(1). pii: E1. doi: 10.3390/children7010001.

3.

Thermosensitive Hydrogel Based on PEO-PPO-PEO Poloxamers for a Controlled In Situ Release of Recombinant Adeno-Associated Viral Vectors for Effective Gene Therapy of Cartilage Defects.

Madry H, Gao L, Rey-Rico A, Venkatesan JK, Müller-Brandt K, Cai X, Goebel L, Schmitt G, Speicher-Mentges S, Zurakowski D, Menger MD, Laschke MW, Cucchiarini M.

Adv Mater. 2020 Jan;32(2):e1906508. doi: 10.1002/adma.201906508. Epub 2019 Nov 25.

PMID:
31763733
4.

Preferential targeting of MCL-1 by a hydrocarbon-stapled BIM BH3 peptide.

Hadji A, Schmitt GK, Schnorenberg MR, Roach L, Hickey CM, Leak LB, Tirrell MV, LaBelle JL.

Oncotarget. 2019 Oct 22;10(58):6219-6233. doi: 10.18632/oncotarget.27262. eCollection 2019 Oct 22.

5.

Towards the understanding of the enzymatic cleavage of polyisoprene by the dihaem-dioxygenase RoxA.

Schmitt G, Birke J, Jendrossek D.

AMB Express. 2019 Oct 17;9(1):166. doi: 10.1186/s13568-019-0888-0.

6.

Effects of rAAV-Mediated sox9 Overexpression on the Biological Activities of Human Osteoarthritic Articular Chondrocytes in Their Intrinsic Three-Dimensional Environment.

Daniels O, Frisch J, Venkatesan JK, Rey-Rico A, Schmitt G, Cucchiarini M.

J Clin Med. 2019 Oct 7;8(10). pii: E1637. doi: 10.3390/jcm8101637.

7.

Remodeling of Human Osteochondral Defects via rAAV-Mediated Co-Overexpression of TGF-β and IGF-I from Implanted Human Bone Marrow-Derived Mesenchymal Stromal Cells.

Morscheid S, Venkatesan JK, Rey-Rico A, Schmitt G, Cucchiarini M.

J Clin Med. 2019 Aug 28;8(9). pii: E1326. doi: 10.3390/jcm8091326.

8.

Two Different Quinohemoprotein Amine Dehydrogenases Initiate Anaerobic Degradation of Aromatic Amines in Aromatoleum aromaticum EbN1.

Schmitt G, Saft M, Arndt F, Kahnt J, Heider J.

J Bacteriol. 2019 Jul 24;201(16). pii: e00281-19. doi: 10.1128/JB.00281-19. Print 2019 Aug 15.

9.

Therapeutic Effects of rAAV-Mediated Concomittant Gene Transfer and Overexpression of TGF-β and IGF-I on the Chondrogenesis of Human Bone-Marrow-Derived Mesenchymal Stem Cells.

Morscheid S, Rey-Rico A, Schmitt G, Madry H, Cucchiarini M, Venkatesan JK.

Int J Mol Sci. 2019 May 27;20(10). pii: E2591. doi: 10.3390/ijms20102591.

10.

Characterization of an Aldehyde Oxidoreductase From the Mesophilic Bacterium Aromatoleum aromaticum EbN1, a Member of a New Subfamily of Tungsten-Containing Enzymes.

Arndt F, Schmitt G, Winiarska A, Saft M, Seubert A, Kahnt J, Heider J.

Front Microbiol. 2019 Jan 31;10:71. doi: 10.3389/fmicb.2019.00071. eCollection 2019.

11.

Slow cortical potentials neurofeedback in children with ADHD: comorbidity, self-regulation and clinical outcomes 6 months after treatment in a multicenter randomized controlled trial.

Aggensteiner PM, Brandeis D, Millenet S, Hohmann S, Ruckes C, Beuth S, Albrecht B, Schmitt G, Schermuly S, Wörz S, Gevensleben H, Freitag CM, Banaschewski T, Rothenberger A, Strehl U, Holtmann M.

Eur Child Adolesc Psychiatry. 2019 Aug;28(8):1087-1095. doi: 10.1007/s00787-018-01271-8. Epub 2019 Jan 4.

PMID:
30610380
12.

Prevalence of Mental Distress Among Syrian Refugees With Residence Permission in Germany: A Registry-Based Study.

Georgiadou E, Zbidat A, Schmitt GM, Erim Y.

Front Psychiatry. 2018 Aug 28;9:393. doi: 10.3389/fpsyt.2018.00393. eCollection 2018.

13.

Effects of TGF-β Overexpression via rAAV Gene Transfer on the Early Repair Processes in an Osteochondral Defect Model in Minipigs.

Cucchiarini M, Asen AK, Goebel L, Venkatesan JK, Schmitt G, Zurakowski D, Menger MD, Laschke MW, Madry H.

Am J Sports Med. 2018 Jul;46(8):1987-1996. doi: 10.1177/0363546518773709. Epub 2018 May 24.

PMID:
29792508
14.

Effective Remodelling of Human Osteoarthritic Cartilage by sox9 Gene Transfer and Overexpression upon Delivery of rAAV Vectors in Polymeric Micelles.

Rey-Rico A, Venkatesan JK, Schmitt G, Speicher-Mentges S, Madry H, Cucchiarini M.

Mol Pharm. 2018 Jul 2;15(7):2816-2826. doi: 10.1021/acs.molpharmaceut.8b00331. Epub 2018 May 24.

PMID:
29763553
15.

Chondrogenic Differentiation Processes in Human Bone-Marrow Aspirates Seeded in Three-Dimensional-Woven Poly(ɛ-Caprolactone) Scaffolds Enhanced by Recombinant Adeno-Associated Virus-Mediated SOX9 Gene Transfer.

Venkatesan JK, Moutos FT, Rey-Rico A, Estes BT, Frisch J, Schmitt G, Madry H, Guilak F, Cucchiarini M.

Hum Gene Ther. 2018 Nov;29(11):1277-1286. doi: 10.1089/hum.2017.165. Epub 2018 Jun 11.

16.

An innovative investigative approach to characterize the effects observed in a combined fertility study in male and female rats.

Xie J, Funk J, Bopst M, Ottaviani G, Downes N, Hackford S, Villabruna L, Schmitt G, Barrow P.

Regul Toxicol Pharmacol. 2018 Jun;95:339-347. doi: 10.1016/j.yrtph.2018.04.007. Epub 2018 Apr 7.

PMID:
29635059
17.

Temporal Changes in Cardiovascular Remodeling Associated with Football Participation.

Kim JH, Hollowed C, Patel K, Hosny K, Aida H, Gowani Z, Sher S, Shoop JL, Galante A, Clark C, Marshall T, Patterson G, Schmitt G, Ko YA, Quyyumi AA, Baggish AL.

Med Sci Sports Exerc. 2018 Sep;50(9):1892-1898. doi: 10.1249/MSS.0000000000001631.

18.

rAAV-mediated overexpression of TGF-β via vector delivery in polymeric micelles stimulates the biological and reparative activities of human articular chondrocytes in vitro and in a human osteochondral defect model.

Rey-Rico A, Venkatesan JK, Schmitt G, Concheiro A, Madry H, Alvarez-Lorenzo C, Cucchiarini M.

Int J Nanomedicine. 2017 Sep 19;12:6985-6996. doi: 10.2147/IJN.S144579. eCollection 2017.

19.

Adaptations to a Loss-of-Function Mutation in the Betaproteobacterium Aromatoleum aromaticum: Recruitment of Alternative Enzymes for Anaerobic Phenylalanine Degradation.

Schmitt G, Arndt F, Kahnt J, Heider J.

J Bacteriol. 2017 Sep 19;199(20). pii: e00383-17. doi: 10.1128/JB.00383-17. Print 2017 Oct 15.

20.

Juvenile Nonclinical Safety Studies in Support of Pediatric Drug Development.

Barrow PC, Schmitt G.

Methods Mol Biol. 2017;1641:25-67. doi: 10.1007/978-1-4939-7172-5_2.

PMID:
28748457
21.

Impact of mechanical stimulation on the chondrogenic processes in human bone marrow aspirates modified to overexpress sox9 via rAAV vectors.

Venkatesan JK, Frisch J, Rey-Rico A, Schmitt G, Madry H, Cucchiarini M.

J Exp Orthop. 2017 Dec;4(1):22. doi: 10.1186/s40634-017-0097-1. Epub 2017 Jun 21.

22.

The great barrier belief: The blood-brain barrier and considerations for juvenile toxicity studies.

Schmitt G, Parrott N, Prinssen E, Barrow P.

Reprod Toxicol. 2017 Sep;72:129-135. doi: 10.1016/j.reprotox.2017.06.043. Epub 2017 Jun 13. Review.

PMID:
28627392
23.

Peripheral blood aspirates overexpressing IGF-I via rAAV gene transfer undergo enhanced chondrogenic differentiation processes.

Frisch J, Orth P, Rey-Rico A, Venkatesan JK, Schmitt G, Madry H, Kohn D, Cucchiarini M.

J Cell Mol Med. 2017 Nov;21(11):2748-2758. doi: 10.1111/jcmm.13190. Epub 2017 May 3.

24.

Effects of combined rAAV-mediated TGF-β and sox9 gene transfer and overexpression on the metabolic and chondrogenic activities in human bone marrow aspirates.

Tao K, Rey-Rico A, Frisch J, Venkatesan JK, Schmitt G, Madry H, Lin J, Cucchiarini M.

J Exp Orthop. 2017 Dec;4(1):4. doi: 10.1186/s40634-017-0077-5. Epub 2017 Feb 7.

25.

Genetic Modification of Human Peripheral Blood Aspirates Using Recombinant Adeno-Associated Viral Vectors for Articular Cartilage Repair with a Focus on Chondrogenic Transforming Growth Factor-β Gene Delivery.

Frisch J, Orth P, Venkatesan JK, Rey-Rico A, Schmitt G, Kohn D, Madry H, Cucchiarini M.

Stem Cells Transl Med. 2017 Jan;6(1):249-260. doi: 10.5966/sctm.2016-0149. Epub 2016 Aug 29.

26.

From the Cover: The Minipig is a Suitable Non-Rodent Model in the Safety Assessment of Single Stranded Oligonucleotides.

Braendli-Baiocco A, Festag M, Dumong Erichsen K, Persson R, Mihatsch MJ, Fisker N, Funk J, Mohr S, Constien R, Ploix C, Brady K, Berrera M, Altmann B, Lenz B, Albassam M, Schmitt G, Weiser T, Schuler F, Singer T, Tessier Y.

Toxicol Sci. 2017 May 1;157(1):112-128. doi: 10.1093/toxsci/kfx025.

27.

Nonclinical Safety Considerations for the Development of Pediatric-First Drugs: An Industry View.

Schmitt G, Ridings J, De Schaepdrijver L, van Doesum-Wolters FLC, Cappon GD, Hartmann A.

Ther Innov Regul Sci. 2016 Sep;50(5):632-638. doi: 10.1177/2168479016642813. Epub 2016 Jul 10.

PMID:
30231752
28.

Erratum to: Clinical trial considerations on male contraception and collection of pregnancy information from female partner: update.

Banholzer ML, Wandel C, Barrow P, Mannino M, Schmitt G, Guérard M, Müller L, Greig G, Amemiya K, Peck R, Singer T, Doessegger L.

Clin Transl Med. 2016 Dec;5(1):30. doi: 10.1186/s40169-016-0115-4. Epub 2016 Aug 12. No abstract available.

29.

Effects of rAAV-mediated FGF-2 gene transfer and overexpression upon the chondrogenic differentiation processes in human bone marrow aspirates.

Frisch J, Venkatesan JK, Rey-Rico A, Zawada AM, Schmitt G, Madry H, Cucchiarini M.

J Exp Orthop. 2016 Dec;3(1):16. doi: 10.1186/s40634-016-0052-6. Epub 2016 Jul 29.

30.

Clinical trial considerations on male contraception and collection of pregnancy information from female partner: update.

Banholzer ML, Wandel C, Barrow P, Mannino M, Schmitt G, Guérard M, Müller L, Greig G, Amemiya K, Peck R, Singer T, Doessegger L.

Clin Transl Med. 2016 Dec;5(1):23. doi: 10.1186/s40169-016-0103-8. Epub 2016 Jul 25. Erratum in: Clin Transl Med. 2016 Dec;5(1):30.

31.

PEO-PPO-PEO Carriers for rAAV-Mediated Transduction of Human Articular Chondrocytes in Vitro and in a Human Osteochondral Defect Model.

Rey-Rico A, Frisch J, Venkatesan JK, Schmitt G, Rial-Hermida I, Taboada P, Concheiro A, Madry H, Alvarez-Lorenzo C, Cucchiarini M.

ACS Appl Mater Interfaces. 2016 Aug 17;8(32):20600-13. doi: 10.1021/acsami.6b06509. Epub 2016 Aug 3.

PMID:
27404480
32.

Effects of GlyT1 inhibition on erythropoiesis and iron homeostasis in rats.

Winter M, Funk J, Körner A, Alberati D, Christen F, Schmitt G, Altmann B, Pospischil A, Singer T.

Exp Hematol. 2016 Oct;44(10):964-974.e4. doi: 10.1016/j.exphem.2016.07.003. Epub 2016 Jul 9.

PMID:
27403535
33.

Regulatory Approaches to Nonclinical Reproductive Toxicity Testing of Anti-Cancer Drugs.

Barrow P, Schmitt G.

Anticancer Agents Med Chem. 2017;17(9):1171-1183. doi: 10.2174/1871520616666160613122702. Review.

PMID:
27297974
34.

New Delhi metallo-beta-lactamase-1-producing Acinetobacter spp. infection: report of a survivor.

Schuelter-Trevisol F, Schmitt GJ, Araújo JM, Souza LB, Nazário JG, Januário RL, Mello RS, Trevisol DJ.

Rev Soc Bras Med Trop. 2016 Feb;49(1):130-4. doi: 10.1590/0037-8682-0150-2015.

35.

rAAV-mediated combined gene transfer and overexpression of TGF-β and SOX9 remodels human osteoarthritic articular cartilage.

Tao K, Rey-Rico A, Frisch J, Venkatesan JK, Schmitt G, Madry H, Lin J, Cucchiarini M.

J Orthop Res. 2016 Dec;34(12):2181-2190. doi: 10.1002/jor.23228. Epub 2016 Mar 21.

36.

Variability in Regularity: Mining Temporal Mobility Patterns in London, Singapore and Beijing Using Smart-Card Data.

Zhong C, Batty M, Manley E, Wang J, Wang Z, Chen F, Schmitt G.

PLoS One. 2016 Feb 12;11(2):e0149222. doi: 10.1371/journal.pone.0149222. eCollection 2016.

37.

Co-overexpression of TGF-β and SOX9 via rAAV gene transfer modulates the metabolic and chondrogenic activities of human bone marrow-derived mesenchymal stem cells.

Tao K, Frisch J, Rey-Rico A, Venkatesan JK, Schmitt G, Madry H, Lin J, Cucchiarini M.

Stem Cell Res Ther. 2016 Feb 1;7:20. doi: 10.1186/s13287-016-0280-9.

38.

TGF-β gene transfer and overexpression via rAAV vectors stimulates chondrogenic events in human bone marrow aspirates.

Frisch J, Rey-Rico A, Venkatesan JK, Schmitt G, Madry H, Cucchiarini M.

J Cell Mol Med. 2016 Mar;20(3):430-40. doi: 10.1111/jcmm.12774. Epub 2016 Jan 25.

39.

An unnatural death by propan-1-ol and propan-2-ol.

Skopp G, Gutmann I, Schwarz CS, Schmitt G.

Int J Legal Med. 2016 Jul;130(4):975-980. doi: 10.1007/s00414-015-1302-3. Epub 2015 Dec 28.

PMID:
26712504
40.

rAAV-mediated overexpression of sox9, TGF-β and IGF-I in minipig bone marrow aspirates to enhance the chondrogenic processes for cartilage repair.

Frisch J, Rey-Rico A, Venkatesan JK, Schmitt G, Madry H, Cucchiarini M.

Gene Ther. 2016 Mar;23(3):247-55. doi: 10.1038/gt.2015.106. Epub 2015 Nov 19.

PMID:
26583804
41.

Functional analysis and transcriptional output of the Göttingen minipig genome.

Heckel T, Schmucki R, Berrera M, Ringshandl S, Badi L, Steiner G, Ravon M, Küng E, Kuhn B, Kratochwil NA, Schmitt G, Kiialainen A, Nowaczyk C, Daff H, Khan AP, Lekolool I, Pelle R, Okoth E, Bishop R, Daubenberger C, Ebeling M, Certa U.

BMC Genomics. 2015 Nov 14;16:932. doi: 10.1186/s12864-015-2119-7.

42.

What technical platform is needed for non-traumatic abdominal emergencies? Can we be realistic yet effective?

Pocard M, Schmitt G, Niel S.

J Visc Surg. 2015 Dec;152(6 Suppl):S55-6. doi: 10.1016/j.jviscsurg.2015.09.020. Epub 2015 Oct 21. No abstract available.

PMID:
26507769
43.

[Diuretics and their potential effect on breath-alcohol concentration--a case report].

Schmitt G, Skopp G.

Arch Kriminol. 2015 May-Jun;235(5-6):172-81. German.

PMID:
26427279
44.

Single-sided Nuclear Magnetic Resonance for condition monitoring of cross-linked polyethylene exposed to aggressive media.

Adams A, Piechatzek A, Schmitt G, Siegmund G.

Anal Chim Acta. 2015 Aug 5;887:163-171. doi: 10.1016/j.aca.2015.07.005. Epub 2015 Aug 7.

PMID:
26320798
45.

PEO-PPO-PEO micelles as effective rAAV-mediated gene delivery systems to target human mesenchymal stem cells without altering their differentiation potency.

Rey-Rico A, Venkatesan JK, Frisch J, Rial-Hermida I, Schmitt G, Concheiro A, Madry H, Alvarez-Lorenzo C, Cucchiarini M.

Acta Biomater. 2015 Nov;27:42-52. doi: 10.1016/j.actbio.2015.08.046. Epub 2015 Aug 28.

PMID:
26320543
46.

Enzymes of anaerobic ethylbenzene and p-ethylphenol catabolism in 'Aromatoleum aromaticum': differentiation and differential induction.

Muhr E, Schühle K, Clermont L, Sünwoldt K, Kleinsorge D, Seyhan D, Kahnt J, Schall I, Cordero PR, Schmitt G, Heider J.

Arch Microbiol. 2015 Nov;197(9):1051-62. doi: 10.1007/s00203-015-1142-z. Epub 2015 Aug 15.

PMID:
26275558
47.

Chondrogenic Differentiation Processes in Human Bone Marrow Aspirates upon rAAV-Mediated Gene Transfer and Overexpression of the Insulin-Like Growth Factor I.

Frisch J, Rey-Rico A, Venkatesan JK, Schmitt G, Madry H, Cucchiarini M.

Tissue Eng Part A. 2015 Sep;21(17-18):2460-71. doi: 10.1089/ten.TEA.2014.0679. Epub 2015 Jul 22.

48.

Resin-based luting agents and color stability of bonded ceramic veneers.

Almeida JR, Schmitt GU, Kaizer MR, Boscato N, Moraes RR.

J Prosthet Dent. 2015 Aug;114(2):272-7. doi: 10.1016/j.prosdent.2015.01.008. Epub 2015 Apr 14.

PMID:
25882974
49.

Effective and durable genetic modification of human mesenchymal stem cells via controlled release of rAAV vectors from self-assembling peptide hydrogels with a maintained differentiation potency.

Rey-Rico A, Venkatesan JK, Frisch J, Schmitt G, Monge-Marcet A, Lopez-Chicon P, Mata A, Semino C, Madry H, Cucchiarini M.

Acta Biomater. 2015 May;18:118-27. doi: 10.1016/j.actbio.2015.02.013. Epub 2015 Feb 21.

PMID:
25712390
50.

Contamination of Composite Resin by Glove Powder and Saliva Contaminants: Impact on Mechanical Properties and Incremental Layer Debonding.

Martins NM, Schmitt GU, Oliveira HL, Madruga MM, Moraes RR, Cenci MS.

Oper Dent. 2015 Jul-Aug;40(4):396-402. doi: 10.2341/13-105-L. Epub 2015 Feb 23.

PMID:
25706615

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