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Items: 1 to 50 of 170

1.

Identification of a novel caspase cleavage site in huntingtin that regulates mutant huntingtin clearance.

Martin DDO, Schmidt ME, Nguyen YT, Lazic N, Hayden MR.

FASEB J. 2018 Nov 13:fj201701510RRR. doi: 10.1096/fj.201701510RRR. [Epub ahead of print]

PMID:
30423259
2.

Secondary prevention of Alzheimer's dementia: neuroimaging contributions.

Ten Kate M, Ingala S, Schwarz AJ, Fox NC, Chételat G, van Berckel BNM, Ewers M, Foley C, Gispert JD, Hill D, Irizarry MC, Lammertsma AA, Molinuevo JL, Ritchie C, Scheltens P, Schmidt ME, Visser PJ, Waldman A, Wardlaw J, Haller S, Barkhof F.

Alzheimers Res Ther. 2018 Oct 30;10(1):112. doi: 10.1186/s13195-018-0438-z.

3.

AMYPAD Diagnostic and Patient Management Study: Rationale and design.

Frisoni GB, Barkhof F, Altomare D, Berkhof J, Boccardi M, Canzoneri E, Collij L, Drzezga A, Farrar G, Garibotto V, Gismondi R, Gispert JD, Jessen F, Kivipelto M, Lopes Alves I, Molinuevo JL, Nordberg A, Payoux P, Ritchie C, Savicheva I, Scheltens P, Schmidt ME, Schott J, Stephens A, van Berckel B, Vellas B, Walker Z, Raffa N.

Alzheimers Dement. 2018 Oct 16. pii: S1552-5260(18)33528-3. doi: 10.1016/j.jalz.2018.09.003. [Epub ahead of print]

4.

Targeting Exercise Interventions to Patients With Cancer in Need: An Individual Patient Data Meta-Analysis.

Buffart LM, Sweegers MG, May AM, Chinapaw MJ, van Vulpen JK, Newton RU, Galvão DA, Aaronson NK, Stuiver MM, Jacobsen PB, Verdonck-de Leeuw IM, Steindorf K, Irwin ML, Hayes S, Griffith KA, Lucia A, Herrero-Roman F, Mesters I, van Weert E, Knoop H, Goedendorp MM, Mutrie N, Daley AJ, McConnachie A, Bohus M, Thorsen L, Schulz KH, Short CE, James EL, Plotnikoff RC, Arbane G, Schmidt ME, Potthoff K, van Beurden M, Oldenburg HS, Sonke GS, van Harten WH, Garrod R, Schmitz KH, Winters-Stone KM, Velthuis MJ, Taaffe DR, van Mechelen W, José Kersten M, Nollet F, Wenzel J, Wiskemann J, Brug J, Courneya KS.

J Natl Cancer Inst. 2018 Nov 1;110(11):1190-1200. doi: 10.1093/jnci/djy161.

PMID:
30299508
5.

Effects and moderators of exercise on muscle strength, muscle function and aerobic fitness in patients with cancer: a meta-analysis of individual patient data.

Sweegers MG, Altenburg TM, Brug J, May AM, van Vulpen JK, Aaronson NK, Arbane G, Bohus M, Courneya KS, Daley AJ, Galvao DA, Garrod R, Griffith KA, Van Harten WH, Hayes SC, Herrero-Román F, Kersten MJ, Lucia A, McConnachie A, van Mechelen W, Mutrie N, Newton RU, Nollet F, Potthoff K, Schmidt ME, Schmitz KH, Schulz KH, Sonke G, Steindorf K, Stuiver MM, Taaffe DR, Thorsen L, Twisk JW, Velthuis MJ, Wenzel J, Winters-Stone KM, Wiskemann J, Chin A Paw MJ, Buffart LM.

Br J Sports Med. 2018 Sep 4. pii: bjsports-2018-099191. doi: 10.1136/bjsports-2018-099191. [Epub ahead of print] Review.

PMID:
30181323
6.

Cytokines and CD8 T cell immunity during respiratory syncytial virus infection.

Schmidt ME, Varga SM.

Cytokine. 2018 Jul 18. pii: S1043-4666(18)30297-7. doi: 10.1016/j.cyto.2018.07.012. [Epub ahead of print]

PMID:
30031680
7.

Altering cortical input unmasks synaptic phenotypes in the YAC128 cortico-striatal co-culture model of Huntington disease.

Schmidt ME, Buren C, Mackay JP, Cheung D, Dal Cengio L, Raymond LA, Hayden MR.

BMC Biol. 2018 Jun 27;16(1):58. doi: 10.1186/s12915-018-0526-3.

8.

Validation of inflammatory genetic variants associated with long-term cancer related fatigue in a large breast cancer cohort.

Kühl T, Behrens S, Jung AY, Obi N, Thöne K, Schmidt ME, Becher H, Chang-Claude J.

Brain Behav Immun. 2018 Oct;73:252-260. doi: 10.1016/j.bbi.2018.05.009. Epub 2018 May 18.

PMID:
29763737
9.

Quality of life, problems, and needs of disease-free breast cancer survivors 5 years after diagnosis.

Schmidt ME, Wiskemann J, Steindorf K.

Qual Life Res. 2018 Aug;27(8):2077-2086. doi: 10.1007/s11136-018-1866-8. Epub 2018 May 8.

PMID:
29740782
10.

The CD8 T Cell Response to Respiratory Virus Infections.

Schmidt ME, Varga SM.

Front Immunol. 2018 Apr 9;9:678. doi: 10.3389/fimmu.2018.00678. eCollection 2018. Review.

11.

Fatty Acid Amide Hydrolase Inhibition by JNJ-42165279: A Multiple-Ascending Dose and a Positron Emission Tomography Study in Healthy Volunteers.

Postnov A, Schmidt ME, Pemberton DJ, de Hoon J, van Hecken A, van den Boer M, Zannikos P, van der Ark P, Palmer JA, Rassnick S, Celen S, Bormans G, van Laere K.

Clin Transl Sci. 2018 Jul;11(4):397-404. doi: 10.1111/cts.12548. Epub 2018 Mar 25.

12.

Controlled fabrication of electrically contacted carbon nanoscrolls.

Schmidt ME, Hammam AMM, Iwasaki T, Kanzaki T, Muruganathan M, Ogawa S, Mizuta H.

Nanotechnology. 2018 Jun 8;29(23):235605. doi: 10.1088/1361-6528/aab82c. Epub 2018 Mar 20.

PMID:
29557785
13.

Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease.

Ehrnhoefer DE, Martin DDO, Schmidt ME, Qiu X, Ladha S, Caron NS, Skotte NH, Nguyen YTN, Vaid K, Southwell AL, Engemann S, Franciosi S, Hayden MR.

Acta Neuropathol Commun. 2018 Mar 6;6(1):16. doi: 10.1186/s40478-018-0518-0.

14.

[Exercise and Physical Activity During and after Cancer - Who Benefits most, What is Proven?]

Steindorf K, Schmidt ME, Zimmer P.

Dtsch Med Wochenschr. 2018 Mar;143(5):309-315. doi: 10.1055/s-0043-106885. Epub 2018 Mar 5. German.

PMID:
29506297
15.

Structurally Controlled Large-Area 10 nm Pitch Graphene Nanomesh by Focused Helium Ion Beam Milling.

Schmidt ME, Iwasaki T, Muruganathan M, Haque M, Van Ngoc H, Ogawa S, Mizuta H.

ACS Appl Mater Interfaces. 2018 Mar 28;10(12):10362-10368. doi: 10.1021/acsami.8b00427. Epub 2018 Mar 14.

PMID:
29485851
16.

Exercise behavior and physical fitness in patients with advanced lung cancer.

Titz C, Hummler S, Schmidt ME, Thomas M, Steins M, Wiskemann J.

Support Care Cancer. 2018 Aug;26(8):2725-2736. doi: 10.1007/s00520-018-4105-5. Epub 2018 Feb 26.

PMID:
29480444
17.

L-Thyroxine intake as a potential risk factor for the development of fatigue in breast cancer patients undergoing chemotherapy.

Schmidt ME, Wiskemann J, Johnson T, Habermann N, Schneeweiss A, Steindorf K.

Support Care Cancer. 2018 Aug;26(8):2561-2569. doi: 10.1007/s00520-018-4095-3. Epub 2018 Feb 14.

PMID:
29445858
18.

Biomarker pattern of ARIA-E participants in phase 3 randomized clinical trials with bapineuzumab.

Liu E, Wang D, Sperling R, Salloway S, Fox NC, Blennow K, Scheltens P, Schmidt ME, Streffer J, Novak G, Einstein S, Booth K, Ketter N, Brashear HR; ELN115727-301/302 Investigator Group.

Neurology. 2018 Mar 6;90(10):e877-e886. doi: 10.1212/WNL.0000000000005060. Epub 2018 Feb 2.

PMID:
29429971
19.

Diffusion kurtosis imaging allows the early detection and longitudinal follow-up of amyloid-β-induced pathology.

Praet J, Manyakov NV, Muchene L, Mai Z, Terzopoulos V, de Backer S, Torremans A, Guns PJ, Van De Casteele T, Bottelbergs A, Van Broeck B, Sijbers J, Smeets D, Shkedy Z, Bijnens L, Pemberton DJ, Schmidt ME, Van der Linden A, Verhoye M.

Alzheimers Res Ther. 2018 Jan 9;10(1):1. doi: 10.1186/s13195-017-0329-8.

20.

Determining best practices in reconnoitering sites for habitability potential on Mars using a semi-autonomous rover: A GeoHeuristic Operational Strategies Test.

Yingst RA, Berger J, Cohen BA, Hynek B, Schmidt ME.

Acta Astronaut. 2017 Mar;132:268-281. doi: 10.1016/j.actaastro.2016.12.018. Epub 2016 Dec 18.

21.

Memory CD8 T cells mediate severe immunopathology following respiratory syncytial virus infection.

Schmidt ME, Knudson CJ, Hartwig SM, Pewe LL, Meyerholz DK, Langlois RA, Harty JT, Varga SM.

PLoS Pathog. 2018 Jan 2;14(1):e1006810. doi: 10.1371/journal.ppat.1006810. eCollection 2018 Jan.

22.

Effects of physical exercise on markers of inflammation in breast cancer patients during adjuvant chemotherapy.

van Vulpen JK, Schmidt ME, Velthuis MJ, Wiskemann J, Schneeweiss A, Vermeulen RCH, Habermann N, Ulrich CM, Peeters PHM, van der Wall E, May AM, Steindorf K.

Breast Cancer Res Treat. 2018 Apr;168(2):421-431. doi: 10.1007/s10549-017-4608-7. Epub 2017 Dec 12.

PMID:
29235043
23.

Determinants of physical, affective, and cognitive fatigue during breast cancer therapy and 12 months follow-up.

Schmidt ME, Wiskemann J, Schneeweiss A, Potthoff K, Ulrich CM, Steindorf K.

Int J Cancer. 2018 Mar 15;142(6):1148-1157. doi: 10.1002/ijc.31138. Epub 2017 Nov 13.

PMID:
29082588
24.

Host genetics play a critical role in controlling CD8 T cell function and lethal immunopathology during chronic viral infection.

Christiaansen AF, Schmidt ME, Hartwig SM, Varga SM.

PLoS Pathog. 2017 Jul 17;13(7):e1006498. doi: 10.1371/journal.ppat.1006498. eCollection 2017 Jul.

25.

Impact of HSCT Conditioning and Glucocorticoid Dose on Exercise Adherence and Response.

Wiskemann J, Herzog B, Kuehl R, Schmidt ME, Steindorf K, Schwerdtfeger R, Dreger P, Bohus M.

Med Sci Sports Exerc. 2017 Nov;49(11):2143-2150. doi: 10.1249/MSS.0000000000001357.

PMID:
28657933
26.

Dissociation of Down syndrome and Alzheimer's disease effects with imaging.

Matthews DC, Lukic AS, Andrews RD, Marendic B, Brewer J, Rissman RA, Mosconi L, Strother SC, Wernick MN, Mobley WC, Ness S, Schmidt ME, Rafii MS.

Alzheimers Dement (N Y). 2016 Jun;2(2):69-81. doi: 10.1016/j.trci.2016.02.004.

27.

Redox stratification of an ancient lake in Gale crater, Mars.

Hurowitz JA, Grotzinger JP, Fischer WW, McLennan SM, Milliken RE, Stein N, Vasavada AR, Blake DF, Dehouck E, Eigenbrode JL, Fairén AG, Frydenvang J, Gellert R, Grant JA, Gupta S, Herkenhoff KE, Ming DW, Rampe EB, Schmidt ME, Siebach KL, Stack-Morgan K, Sumner DY, Wiens RC.

Science. 2017 Jun 2;356(6341). pii: eaah6849. doi: 10.1126/science.aah6849. Epub 2017 Jun 1.

28.

Nitrogen Gas Field Ion Source (GFIS) Focused Ion Beam (FIB) Secondary Electron Imaging: A First Look.

Schmidt ME, Yasaka A, Akabori M, Mizuta H.

Microsc Microanal. 2017 Aug;23(4):758-768. doi: 10.1017/S1431927617000502. Epub 2017 May 10.

PMID:
28487005
29.

The value of PET ligand discovery to CNS drug development.

Schmidt ME, Andrés JI.

Future Med Chem. 2017 Mar;9(4):351-356. doi: 10.4155/fmc-2017-0018. Epub 2017 Mar 6. No abstract available.

PMID:
28263084
30.

Modulation of the host immune response by respiratory syncytial virus proteins.

Schmidt ME, Varga SM.

J Microbiol. 2017 Mar;55(3):161-171. doi: 10.1007/s12275-017-7045-8. Epub 2017 Feb 28. Review.

PMID:
28243940
31.

The epidemiologic characteristics, temporal trends, predictors of death, and discharge disposition in patients with a diagnosis of sepsis: A cross-sectional retrospective cohort study.

Elfeky S, Golabi P, Otgonsuren M, Djurkovic S, Schmidt ME, Younossi ZM.

J Crit Care. 2017 Jun;39:48-55. doi: 10.1016/j.jcrc.2017.01.006. Epub 2017 Jan 20.

PMID:
28199891
32.

Effects of exercise on sleep problems in breast cancer patients receiving radiotherapy: a randomized clinical trial.

Steindorf K, Wiskemann J, Ulrich CM, Schmidt ME.

Breast Cancer Res Treat. 2017 Apr;162(3):489-499. doi: 10.1007/s10549-017-4141-8. Epub 2017 Feb 8.

PMID:
28181128
33.

Discovery of N-(Pyridin-4-yl)-1,5-naphthyridin-2-amines as Potential Tau Pathology PET Tracers for Alzheimer's Disease.

Rombouts FJ, Andrés JI, Ariza M, Alonso JM, Austin N, Bottelbergs A, Chen L, Chupakhin V, Cleiren E, Fierens K, Fontana A, Langlois X, Leenaerts JE, Mariën J, Martínez Lamenca C, Salter R, Schmidt ME, Te Riele P, Wintmolders C, Trabanco AA, Zhang W, Macdonald G, Moechars D.

J Med Chem. 2017 Feb 23;60(4):1272-1291. doi: 10.1021/acs.jmedchem.6b01173. Epub 2017 Feb 10.

PMID:
28106992
34.

Self-reported physical activity behavior of breast cancer survivors during and after adjuvant therapy: 12 months follow-up of two randomized exercise intervention trials.

Schmidt ME, Wiskemann J, Ulrich CM, Schneeweiss A, Steindorf K.

Acta Oncol. 2017 Apr;56(4):618-627. doi: 10.1080/0284186X.2016.1275776. Epub 2017 Jan 13.

PMID:
28084890
35.

Partial hydrogenation induced interaction in a graphene-SiO2 interface: irreversible modulation of device characteristics.

Iwasaki T, Muruganathan M, Schmidt ME, Mizuta H.

Nanoscale. 2017 Jan 26;9(4):1662-1669. doi: 10.1039/c6nr08117g.

PMID:
28074959
36.

Effects and moderators of exercise on quality of life and physical function in patients with cancer: An individual patient data meta-analysis of 34 RCTs.

Buffart LM, Kalter J, Sweegers MG, Courneya KS, Newton RU, Aaronson NK, Jacobsen PB, May AM, Galvão DA, Chinapaw MJ, Steindorf K, Irwin ML, Stuiver MM, Hayes S, Griffith KA, Lucia A, Mesters I, van Weert E, Knoop H, Goedendorp MM, Mutrie N, Daley AJ, McConnachie A, Bohus M, Thorsen L, Schulz KH, Short CE, James EL, Plotnikoff RC, Arbane G, Schmidt ME, Potthoff K, van Beurden M, Oldenburg HS, Sonke GS, van Harten WH, Garrod R, Schmitz KH, Winters-Stone KM, Velthuis MJ, Taaffe DR, van Mechelen W, Kersten MJ, Nollet F, Wenzel J, Wiskemann J, Verdonck-de Leeuw IM, Brug J.

Cancer Treat Rev. 2017 Jan;52:91-104. doi: 10.1016/j.ctrv.2016.11.010. Epub 2016 Dec 5. Review.

37.

Muscle strength in breast cancer patients receiving different treatment regimes.

Klassen O, Schmidt ME, Ulrich CM, Schneeweiss A, Potthoff K, Steindorf K, Wiskemann J.

J Cachexia Sarcopenia Muscle. 2017 Apr;8(2):305-316. doi: 10.1002/jcsm.12165. Epub 2016 Nov 28.

38.

Salting-out assisted liquid-liquid extraction and partial least squares regression to assay low molecular weight polycyclic aromatic hydrocarbons leached from soils and sediments.

Bressan LP, do Nascimento PC, Schmidt MEP, Faccin H, de Machado LC, Bohrer D.

Spectrochim Acta A Mol Biomol Spectrosc. 2017 Feb 15;173:749-756. doi: 10.1016/j.saa.2016.10.036. Epub 2016 Oct 21.

PMID:
27794240
39.

Effects of 12-week resistance training during radiotherapy in breast cancer patients.

Wiskemann J, Schmidt ME, Klassen O, Debus J, Ulrich CM, Potthoff K, Steindorf K.

Scand J Med Sci Sports. 2017 Nov;27(11):1500-1510. doi: 10.1111/sms.12777. Epub 2016 Oct 5.

PMID:
27704628
40.

What We Observe In Vivo Is Not Always What We See In Vitro: Development and Validation of 11C-JNJ-42491293, A Novel Radioligand for mGluR2.

Leurquin-Sterk G, Celen S, Van Laere K, Koole M, Bormans G, Langlois X, Van Hecken A, Te Riele P, Alcázar J, Verbruggen A, de Hoon J, Andrés JI, Schmidt ME.

J Nucl Med. 2017 Jan;58(1):110-116. doi: 10.2967/jnumed.116.176628. Epub 2016 Jul 28.

41.

Determinants of exercise adherence and contamination in a randomized controlled trial in cancer patients during and after allogeneic HCT.

Kuehl R, Schmidt ME, Dreger P, Steindorf K, Bohus M, Wiskemann J.

Support Care Cancer. 2016 Oct;24(10):4327-37. doi: 10.1007/s00520-016-3271-6. Epub 2016 May 17.

PMID:
27189616
42.

Mineralogy, provenance, and diagenesis of a potassic basaltic sandstone on Mars: CheMin X-ray diffraction of the Windjana sample (Kimberley area, Gale Crater).

Treiman AH, Bish DL, Vaniman DT, Chipera SJ, Blake DF, Ming DW, Morris RV, Bristow TF, Morrison SM, Baker MB, Rampe EB, Downs RT, Filiberto J, Glazner AF, Gellert R, Thompson LM, Schmidt ME, Le Deit L, Wiens RC, McAdam AC, Achilles CN, Edgett KS, Farmer JD, Fendrich KV, Grotzinger JP, Gupta S, Morookian JM, Newcombe ME, Rice MS, Spray JG, Stolper EM, Sumner DY, Vasavada AR, Yen AS.

J Geophys Res Planets. 2016 Jan;121(1):75-106. Epub 2016 Jan 29.

43.

Large-scale nanoelectromechanical switches based on directly deposited nanocrystalline graphene on insulating substrates.

Sun J, Schmidt ME, Muruganathan M, Chong HM, Mizuta H.

Nanoscale. 2016 Mar 28;8(12):6659-65. doi: 10.1039/c6nr00253f.

PMID:
26948477
44.

Resistance Exercise and Inflammation in Breast Cancer Patients Undergoing Adjuvant Radiation Therapy: Mediation Analysis From a Randomized, Controlled Intervention Trial.

Schmidt ME, Meynköhn A, Habermann N, Wiskemann J, Oelmann J, Hof H, Wessels S, Klassen O, Debus J, Potthoff K, Steindorf K, Ulrich CM.

Int J Radiat Oncol Biol Phys. 2016 Feb 1;94(2):329-37. doi: 10.1016/j.ijrobp.2015.10.058. Epub 2015 Nov 2.

PMID:
26853341
45.

In vivo molecular neuroimaging of glucose utilization and its association with fibrillar amyloid-β load in aged APPPS1-21 mice.

Waldron AM, Wintmolders C, Bottelbergs A, Kelley JB, Schmidt ME, Stroobants S, Langlois X, Staelens S.

Alzheimers Res Ther. 2015 Dec 15;7(1):76. doi: 10.1186/s13195-015-0158-6.

46.

Cancer-related fatigue shows a stable association with diurnal cortisol dysregulation in breast cancer patients.

Schmidt ME, Semik J, Habermann N, Wiskemann J, Ulrich CM, Steindorf K.

Brain Behav Immun. 2016 Feb;52:98-105. doi: 10.1016/j.bbi.2015.10.005. Epub 2015 Oct 9.

PMID:
26456694
47.

Amyloid-β 11C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials.

Liu E, Schmidt ME, Margolin R, Sperling R, Koeppe R, Mason NS, Klunk WE, Mathis CA, Salloway S, Fox NC, Hill DL, Les AS, Collins P, Gregg KM, Di J, Lu Y, Tudor IC, Wyman BT, Booth K, Broome S, Yuen E, Grundman M, Brashear HR; Bapineuzumab 301 and 302 Clinical Trial Investigators.

Neurology. 2015 Aug 25;85(8):692-700. doi: 10.1212/WNL.0000000000001877. Epub 2015 Jul 24.

48.

Perspective: The Alzheimer's Disease Neuroimaging Initiative and the role and contributions of the Private Partner Scientific Board (PPSB).

Liu E, Luthman J, Cedarbaum JM, Schmidt ME, Cole PE, Hendrix J, Carrillo MC, Jones-Davis D, Tarver E, Novak G, De Santi S, Soares HD, Potter WZ, Siemers E, Schwarz AJ.

Alzheimers Dement. 2015 Jul;11(7):840-9. doi: 10.1016/j.jalz.2015.04.001. Review.

PMID:
26194317
49.

Factors influencing participation in a randomized controlled resistance exercise intervention study in breast cancer patients during radiotherapy.

Gollhofer SM, Wiskemann J, Schmidt ME, Klassen O, Ulrich CM, Oelmann J, Hof H, Potthoff K, Steindorf K.

BMC Cancer. 2015 Mar 27;15:186. doi: 10.1186/s12885-015-1213-1.

50.

Exercise training intensity prescription in breast cancer survivors: validity of current practice and specific recommendations.

Scharhag-Rosenberger F, Kuehl R, Klassen O, Schommer K, Schmidt ME, Ulrich CM, Wiskemann J, Steindorf K.

J Cancer Surviv. 2015 Dec;9(4):612-9. doi: 10.1007/s11764-015-0437-z. Epub 2015 Feb 26.

PMID:
25711667

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