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Phosphodiesterase 10A Inhibitor Monotherapy Is Not an Effective Treatment of Acute Schizophrenia.

Walling DP, Banerjee A, Dawra V, Boyer S, Schmidt CJ, DeMartinis N.

J Clin Psychopharmacol. 2019 Nov/Dec;39(6):575-582. doi: 10.1097/JCP.0000000000001128.


Evaluating Bioinformatic Pipeline Performance for Forensic Microbiome Analysis*,†,‡.

Kaszubinski SF, Pechal JL, Schmidt CJ, Jordan HR, Benbow ME, Meek MH.

J Forensic Sci. 2019 Oct 28. doi: 10.1111/1556-4029.14213. [Epub ahead of print]


Effects of acute and chronic heat stress on the performance, egg quality, body temperature, and blood gas parameters of laying hens.

Barrett NW, Rowland K, Schmidt CJ, Lamont SJ, Rothschild MF, Ashwell CM, Persia ME.

Poult Sci. 2019 Oct 1. pii: pez541. doi: 10.3382/ps/pez541. [Epub ahead of print]


Variant analysis pipeline for accurate detection of genomic variants from transcriptome sequencing data.

Adetunji MO, Lamont SJ, Abasht B, Schmidt CJ.

PLoS One. 2019 Sep 23;14(9):e0216838. doi: 10.1371/journal.pone.0216838. eCollection 2019.


Genetic lines respond uniquely within the chicken thymic transcriptome to acute heat stress and low dose lipopolysaccharide.

Monson MS, Van Goor AG, Persia ME, Rothschild MF, Schmidt CJ, Lamont SJ.

Sci Rep. 2019 Sep 20;9(1):13649. doi: 10.1038/s41598-019-50051-0.


Phosphodiesterase 9A in Brain Regulates cGMP Signaling Independent of Nitric-Oxide.

Harms JF, Menniti FS, Schmidt CJ.

Front Neurosci. 2019 Aug 23;13:837. doi: 10.3389/fnins.2019.00837. eCollection 2019.


Risk and protective factors related to youth firearm violence: a scoping review and directions for future research.

Schmidt CJ, Rupp L, Pizarro JM, Lee DB, Branas CC, Zimmerman MA.

J Behav Med. 2019 Aug;42(4):706-723. doi: 10.1007/s10865-019-00076-7. Epub 2019 Aug 1. Review.


A Proof-of-Concept Study Evaluating the Phosphodiesterase 10A Inhibitor PF-02545920 in the Adjunctive Treatment of Suboptimally Controlled Symptoms of Schizophrenia.

DeMartinis N 3rd, Lopez RN, Pickering EH, Schmidt CJ, Gertsik L, Walling DP, Ogden A.

J Clin Psychopharmacol. 2019 Jul/Aug;39(4):318-328. doi: 10.1097/JCP.0000000000001047.


Total RNA Analysis of Bacterial Community Structural and Functional Shifts Throughout Vertebrate Decomposition.

Burcham ZM, Cowick CA, Baugher CN, Pechal JL, Schmidt CJ, Rosch JW, Benbow ME, Jordan HR.

J Forensic Sci. 2019 Nov;64(6):1707-1719. doi: 10.1111/1556-4029.14083. Epub 2019 Jun 6.


Depression in the Primary Care Setting.

Ellis P, Kitay B, Schmidt CJ.

N Engl J Med. 2019 Jun 6;380(23):2278. doi: 10.1056/NEJMc1903259. No abstract available.


Natural Selection Footprints Among African Chicken Breeds and Village Ecotypes.

Elbeltagy AR, Bertolini F, Fleming DS, Van Goor A, Ashwell CM, Schmidt CJ, Kugonza DR, Lamont SJ, Rothschild MF.

Front Genet. 2019 May 8;10:376. doi: 10.3389/fgene.2019.00376. eCollection 2019.


Bacterial Community Succession, Transmigration, and Differential Gene Transcription in a Controlled Vertebrate Decomposition Model.

Burcham ZM, Pechal JL, Schmidt CJ, Bose JL, Rosch JW, Benbow ME, Jordan HR.

Front Microbiol. 2019 Apr 18;10:745. doi: 10.3389/fmicb.2019.00745. eCollection 2019.


Machine learning performance in a microbial molecular autopsy context: A cross-sectional postmortem human population study.

Zhang Y, Pechal JL, Schmidt CJ, Jordan HR, Wang WW, Benbow ME, Sze SH, Tarone AM.

PLoS One. 2019 Apr 15;14(4):e0213829. doi: 10.1371/journal.pone.0213829. eCollection 2019.


Detection of critical antibiotic resistance genes through routine microbiome surveillance.

Burcham ZM, Schmidt CJ, Pechal JL, Brooks CP, Rosch JW, Benbow ME, Jordan HR.

PLoS One. 2019 Mar 14;14(3):e0213280. doi: 10.1371/journal.pone.0213280. eCollection 2019.


Cognitive Behavioral Therapy for Veterans With Tinnitus.

Schmidt CJ, Kerns RD, Finkel S, Michaelides E, Henry JA.

Fed Pract. 2018 Aug;35(8):36-46.


Differentially expressed gene networks, biomarkers, long noncoding RNAs, and shared responses with cocaine identified in the midbrains of human opioid abusers.

Saad MH, Rumschlag M, Guerra MH, Savonen CL, Jaster AM, Olson PD, Alazizi A, Luca F, Pique-Regi R, Schmidt CJ, Bannon MJ.

Sci Rep. 2019 Feb 7;9(1):1534. doi: 10.1038/s41598-018-38209-8.


Detection of Selection Signatures Among Brazilian, Sri Lankan, and Egyptian Chicken Populations Under Different Environmental Conditions.

Walugembe M, Bertolini F, Dematawewa CMB, Reis MP, Elbeltagy AR, Schmidt CJ, Lamont SJ, Rothschild MF.

Front Genet. 2019 Jan 14;9:737. doi: 10.3389/fgene.2018.00737. eCollection 2018.


In vitro phosphodiesterase 10A (PDE10A) binding in whole hemisphere human brain using the PET radioligand [18F]MNI-659.

Svedberg MM, Varnäs K, Varrone A, Mitsios N, Mulder J, Gulyás B, Beaumont V, Munoz-Sanjuan I, Zaleska MM, Schmidt CJ, Halldin C, Mrzljak L.

Brain Res. 2019 May 15;1711:140-145. doi: 10.1016/j.brainres.2019.01.021. Epub 2019 Jan 18.


Distinct genes and pathways associated with transcriptome differences in early cardiac development between fast- and slow-growing broilers.

Zhang J, Schmidt CJ, Lamont SJ.

PLoS One. 2018 Dec 5;13(12):e0207715. doi: 10.1371/journal.pone.0207715. eCollection 2018.


Gene expression profiling of the early pathogenesis of wooden breast disease in commercial broiler chickens using RNA-sequencing.

Papah MB, Brannick EM, Schmidt CJ, Abasht B.

PLoS One. 2018 Dec 5;13(12):e0207346. doi: 10.1371/journal.pone.0207346. eCollection 2018.


Opioid Deaths: Trends, Biomarkers, and Potential Drug Interactions Revealed by Decision Tree Analyses.

Saad MH, Savonen CL, Rumschlag M, Todi SV, Schmidt CJ, Bannon MJ.

Front Neurosci. 2018 Oct 23;12:728. doi: 10.3389/fnins.2018.00728. eCollection 2018.


Identifying mechanisms of regulation to model carbon flux during heat stress and generate testable hypotheses.

Hubbard AH, Zhang X, Jastrebski S, Lamont SJ, Singh A, Schmidt CJ.

PLoS One. 2018 Oct 26;13(10):e0205824. doi: 10.1371/journal.pone.0205824. eCollection 2018.


FAANG, establishing metadata standards, validation and best practices for the farmed and companion animal community.

Harrison PW, Fan J, Richardson D, Clarke L, Zerbino D, Cochrane G, Archibald AL, Schmidt CJ, Flicek P.

Anim Genet. 2018 Dec;49(6):520-526. doi: 10.1111/age.12736. Epub 2018 Oct 12.


Nonrheumatoid Fibrinous Pericarditis: A Medical Examiner Algorithm for the Diagnosis of Viral Myocarditis and Use of Molecular Diagnostic Techniques.

Gupta A, Furman J, Kesha K, Diaz F, Schmidt CJ.

Am J Forensic Med Pathol. 2019 Mar;40(1):77-80. doi: 10.1097/PAF.0000000000000434.


Immunomodulatory effects of heat stress and lipopolysaccharide on the bursal transcriptome in two distinct chicken lines.

Monson MS, Van Goor AG, Ashwell CM, Persia ME, Rothschild MF, Schmidt CJ, Lamont SJ.

BMC Genomics. 2018 Aug 30;19(1):643. doi: 10.1186/s12864-018-5033-y.


A Longitudinal Analysis of the Indirect Effect of Violence Exposure on Future Orientation Through Perceived Stress and the Buffering Effect of Family Participation.

Schmidt CJ, Zimmerman MA, Stoddard SA.

Am J Community Psychol. 2018 Sep;62(1-2):62-74. doi: 10.1002/ajcp.12254. Epub 2018 Jun 7.


Telephone-Based Progressive Tinnitus Management for Persons With and Without Traumatic Brain Injury: A Randomized Controlled Trial.

Henry JA, Thielman EJ, Zaugg TL, Kaelin C, McMillan GP, Schmidt CJ, Myers PJ, Carlson KF.

Ear Hear. 2019 Mar/Apr;40(2):227-242. doi: 10.1097/AUD.0000000000000609.


Accidental Carbon Monoxide Poisoning While Driving: A Case Report With Review of the Literature.

Fisher-Hubbard AO, Appleford C, Kesha K, Schmidt CJ, Gupta A.

Am J Forensic Med Pathol. 2018 Sep;39(3):270-272. doi: 10.1097/PAF.0000000000000400. Review.


TransAtlasDB: an integrated database connecting expression data, metadata and variants.

Adetunji MO, Lamont SJ, Schmidt CJ.

Database (Oxford). 2018 Jan 1;2018. doi: 10.1093/database/bay014.


A large-scale survey of the postmortem human microbiome, and its potential to provide insight into the living health condition.

Pechal JL, Schmidt CJ, Jordan HR, Benbow ME.

Sci Rep. 2018 Apr 10;8(1):5724. doi: 10.1038/s41598-018-23989-w.


Correction to Application of Structure-Based Design and Parallel Chemistry to Identify a Potent, Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor.

Helal CJ, Arnold EP, Boyden TL, Chang C, Chappie TA, Fennell KF, Forman MD, Hajos M, Harms JF, Hoffman WE, Humphrey JM, Kang Z, Kleiman RJ, Kormos BL, LaChapelle EA, Lee CW, Lu J, Maklad N, McDowell L, Mente S, O'Connor RE, Pandit J, Piotrowski M, Schmidt AW, Schmidt CJ, Ueno H, Verhoest PR, Yang EX.

J Med Chem. 2018 Apr 26;61(8):3753. doi: 10.1021/acs.jmedchem.8b00475. Epub 2018 Apr 6. No abstract available.


Identification of a Potent, Highly Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor Clinical Candidate.

Helal CJ, Arnold E, Boyden T, Chang C, Chappie TA, Fisher E, Hajos M, Harms JF, Hoffman WE, Humphrey JM, Pandit J, Kang Z, Kleiman RJ, Kormos BL, Lee CW, Lu J, Maklad N, McDowell L, McGinnis D, O'Connor RE, O'Donnell CJ, Ogden A, Piotrowski M, Schmidt CJ, Seymour PA, Ueno H, Vansell N, Verhoest PR, Yang EX.

J Med Chem. 2018 Feb 8;61(3):1001-1018. doi: 10.1021/acs.jmedchem.7b01466. Epub 2018 Jan 16.


Commentary on: Schuman MJ, Hutchins KD. Severe retinal hemorrhages with retinoschisis in infants are not pathognomonic for abusive head trauma. J Forensic Sci 2017;62(3):807-11.

Castellani RJ, DeJong JL, Schmidt CJ.

J Forensic Sci. 2017 Nov;62(6):1677-1678. doi: 10.1111/1556-4029.13628. No abstract available.


Chicken hepatic response to chronic heat stress using integrated transcriptome and metabolome analysis.

Jastrebski SF, Lamont SJ, Schmidt CJ.

PLoS One. 2017 Jul 31;12(7):e0181900. doi: 10.1371/journal.pone.0181900. eCollection 2017.


Evidence and role of phlebitis and lipid infiltration in the onset and pathogenesis of Wooden Breast Disease in modern broiler chickens.

Papah MB, Brannick EM, Schmidt CJ, Abasht B.

Avian Pathol. 2017 Dec;46(6):623-643. doi: 10.1080/03079457.2017.1339346. Epub 2017 Jul 3.


Application of Structure-Based Design and Parallel Chemistry to Identify a Potent, Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor.

Helal CJ, Arnold EP, Boyden TL, Chang C, Chappie TA, Fennell KF, Forman MD, Hajos M, Harms JF, Hoffman WE, Humphrey JM, Kang Z, Kleiman RJ, Kormos BL, Lee CW, Lu J, Maklad N, McDowell L, Mente S, O'Connor RE, Pandit J, Piotrowski M, Schmidt AW, Schmidt CJ, Ueno H, Verhoest PR, Yang EX.

J Med Chem. 2017 Jul 13;60(13):5673-5698. doi: 10.1021/acs.jmedchem.7b00397. Epub 2017 Jun 16. Erratum in: J Med Chem. 2018 Apr 26;61(8):3753.


WebGIVI: a web-based gene enrichment analysis and visualization tool.

Sun L, Zhu Y, Mahmood ASMA, Tudor CO, Ren J, Vijay-Shanker K, Chen J, Schmidt CJ.

BMC Bioinformatics. 2017 May 4;18(1):237. doi: 10.1186/s12859-017-1664-2.


Need for Mental Health Providers in Progressive Tinnitus Management: A Gap in Clinical Care.

Schmidt CJ, Kaelin C, Henselman L, Henry JA.

Fed Pract. 2017 May;34(5):6-9. No abstract available.


The isozyme selective phosphodiesterase-4 inhibitor, ABI-4, attenuates the effects of lipopolysaccharide in human cells and rodent models of peripheral and CNS inflammation.

Hedde JR, Hanks AN, Schmidt CJ, Hughes ZA.

Brain Behav Immun. 2017 Aug;64:285-295. doi: 10.1016/j.bbi.2017.04.015. Epub 2017 Apr 23.


Randomized Controlled Trial in Clinical Settings to Evaluate Effectiveness of Coping Skills Education Used With Progressive Tinnitus Management.

Henry JA, Thielman EJ, Zaugg TL, Kaelin C, Schmidt CJ, Griest S, McMillan GP, Myers P, Rivera I, Baldwin R, Carlson K.

J Speech Lang Hear Res. 2017 May 24;60(5):1378-1397. doi: 10.1044/2016_JSLHR-H-16-0126.


Unique genetic responses revealed in RNA-seq of the spleen of chickens stimulated with lipopolysaccharide and short-term heat.

Van Goor A, Ashwell CM, Persia ME, Rothschild MF, Schmidt CJ, Lamont SJ.

PLoS One. 2017 Feb 6;12(2):e0171414. doi: 10.1371/journal.pone.0171414. eCollection 2017.


Frozen: Thawing and Its Effect on the Postmortem Microbiome in Two Pediatric Cases.

Pechal JL, Schmidt CJ, Jordan HR, Benbow ME.

J Forensic Sci. 2017 Sep;62(5):1399-1405. doi: 10.1111/1556-4029.13419. Epub 2017 Jan 25.


Phosphodiesterase 10A Inhibition Improves Cortico-Basal Ganglia Function in Huntington's Disease Models.

Beaumont V, Zhong S, Lin H, Xu W, Bradaia A, Steidl E, Gleyzes M, Wadel K, Buisson B, Padovan-Neto FE, Chakroborty S, Ward KM, Harms JF, Beltran J, Kwan M, Ghavami A, Häggkvist J, Tóth M, Halldin C, Varrone A, Schaab C, Dybowski JN, Elschenbroich S, Lehtimäki K, Heikkinen T, Park L, Rosinski J, Mrzljak L, Lavery D, West AR, Schmidt CJ, Zaleska MM, Munoz-Sanjuan I.

Neuron. 2016 Dec 21;92(6):1220-1237. doi: 10.1016/j.neuron.2016.10.064. Epub 2016 Dec 1.


Liver transcriptome response to hyperthermic stress in three distinct chicken lines.

Lan X, Hsieh JC, Schmidt CJ, Zhu Q, Lamont SJ.

BMC Genomics. 2016 Nov 22;17(1):955.


Transcriptomic changes throughout post-hatch development in Gallus gallus pituitary.

Pritchett EM, Lamont SJ, Schmidt CJ.

J Mol Endocrinol. 2017 Jan;58(1):43-55. Epub 2016 Nov 17.


Grade-Level Differences in Future-Oriented Self-Concept During Early Adolescence: Potential Relevance to School Nursing.

Stoddard SA, Pierce J, Schmidt CJ.

J Sch Nurs. 2016 Dec;32(6):390-396. Epub 2016 May 24.


Single nucleotide variant discovery of highly inbred Leghorn and Fayoumi chicken breeds using pooled whole genome resequencing data reveals insights into phenotype differences.

Fleming DS, Koltes JE, Fritz-Waters ER, Rothschild MF, Schmidt CJ, Ashwell CM, Persia ME, Reecy JM, Lamont SJ.

BMC Genomics. 2016 Oct 19;17(1):812.


Heat Stress and Lipopolysaccharide Stimulation of Chicken Macrophage-Like Cell Line Activates Expression of Distinct Sets of Genes.

Slawinska A, Hsieh JC, Schmidt CJ, Lamont SJ.

PLoS One. 2016 Oct 13;11(10):e0164575. doi: 10.1371/journal.pone.0164575. eCollection 2016.


Commode Cardia-Death by Valsalva Maneuver: A Case Series.

Fisher-Hubbard AO, Kesha K, Diaz F, Njiwaji C, Chi P, Schmidt CJ.

J Forensic Sci. 2016 Nov;61(6):1541-1545. doi: 10.1111/1556-4029.13196. Epub 2016 Sep 22.

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