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No longer a historical ailment: two cases of childhood scurvy with recommendations for bone health providers.

Alten ED, Chaturvedi A, Cullimore M, Fallon AA, Habben L, Hughes I, O'Malley NT, Rahimi H, Renodin-Mead D, Schmidt BL, Weinberg GA, Weber DR.

Osteoporos Int. 2020 Jan 4. doi: 10.1007/s00198-019-05264-4. [Epub ahead of print]


A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain.

Ramírez-García PD, Retamal JS, Shenoy P, Imlach W, Sykes M, Truong N, Constandil L, Pelissier T, Nowell CJ, Khor SY, Layani LM, Lumb C, Poole DP, Lieu T, Stewart GD, Mai QN, Jensen DD, Latorre R, Scheff NN, Schmidt BL, Quinn JF, Whittaker MR, Veldhuis NA, Davis TP, Bunnett NW.

Nat Nanotechnol. 2019 Dec;14(12):1150-1159. doi: 10.1038/s41565-019-0568-x. Epub 2019 Nov 4.


Granulocyte-Colony Stimulating Factor-Induced Neutrophil Recruitment Provides Opioid-Mediated Endogenous Anti-nociception in Female Mice With Oral Squamous Cell Carcinoma.

Scheff NN, Alemu RG, Klares R 3rd, Wall IM, Yang SC, Dolan JC, Schmidt BL.

Front Mol Neurosci. 2019 Sep 16;12:217. doi: 10.3389/fnmol.2019.00217. eCollection 2019.


Application of a chemical probe to detect neutrophil elastase activation during inflammatory bowel disease.

Anderson BM, Poole DP, Aurelio L, Ng GZ, Fleischmann M, Kasperkiewicz P, Morissette C, Drag M, van Driel IR, Schmidt BL, Vanner SJ, Bunnett NW, Edgington-Mitchell LE.

Sci Rep. 2019 Sep 16;9(1):13295. doi: 10.1038/s41598-019-49840-4.


Protein kinase D and Gβγ mediate sustained nociceptive signaling by biased agonists of protease-activated receptor-2.

Zhao P, Pattison LA, Jensen DD, Jimenez-Vargas NN, Latorre R, Lieu T, Jaramillo JO, Lopez-Lopez C, Poole DP, Vanner SJ, Schmidt BL, Bunnett NW.

J Biol Chem. 2019 Jul 5;294(27):10649-10662. doi: 10.1074/jbc.RA118.006935. Epub 2019 May 29.


Targeted TNF-α Overexpression Drives Salivary Gland Inflammation.

Limaye A, Hall BE, Zhang L, Cho A, Prochazkova M, Zheng C, Walker M, Adewusi F, Burbelo PD, Sun ZJ, Ambudkar IS, Dolan JC, Schmidt BL, Kulkarni AB.

J Dent Res. 2019 Jun;98(6):713-719. doi: 10.1177/0022034519837240. Epub 2019 Apr 8.


G-Protein-Coupled Receptors Are Dynamic Regulators of Digestion and Targets for Digestive Diseases.

Canals M, Poole DP, Veldhuis NA, Schmidt BL, Bunnett NW.

Gastroenterology. 2019 May;156(6):1600-1616. doi: 10.1053/j.gastro.2019.01.266. Epub 2019 Feb 13. Review.


Decitabine attenuates nociceptive behavior in a murine model of bone cancer pain.

Appel CK, Scheff NN, Viet CT, Schmidt BL, Heegaard AM.

Pain. 2019 Mar;160(3):619-631. doi: 10.1097/j.pain.0000000000001442.


Neutrophil-Mediated Endogenous Analgesia Contributes to Sex Differences in Oral Cancer Pain.

Scheff NN, Bhattacharya A, Dowse E, Dang RX, Dolan JC, Wang S, Kim H, Albertson DG, Schmidt BL.

Front Integr Neurosci. 2018 Oct 22;12:52. doi: 10.3389/fnint.2018.00052. eCollection 2018.


Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome.

Jimenez-Vargas NN, Pattison LA, Zhao P, Lieu T, Latorre R, Jensen DD, Castro J, Aurelio L, Le GT, Flynn B, Herenbrink CK, Yeatman HR, Edgington-Mitchell L, Porter CJH, Halls ML, Canals M, Veldhuis NA, Poole DP, McLean P, Hicks GA, Scheff N, Chen E, Bhattacharya A, Schmidt BL, Brierley SM, Vanner SJ, Bunnett NW.

Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7438-E7447. doi: 10.1073/pnas.1721891115. Epub 2018 Jul 16.


Anti-cancer and analgesic effects of resolvin D2 in oral squamous cell carcinoma.

Ye Y, Scheff NN, Bernabé D, Salvo E, Ono K, Liu C, Veeramachaneni R, Viet CT, Viet DT, Dolan JC, Schmidt BL.

Neuropharmacology. 2018 Sep 1;139:182-193. doi: 10.1016/j.neuropharm.2018.07.016. Epub 2018 Jul 20.


Synthetic peripherally-restricted cannabinoid suppresses chemotherapy-induced peripheral neuropathy pain symptoms by CB1 receptor activation.

Mulpuri Y, Marty VN, Munier JJ, Mackie K, Schmidt BL, Seltzman HH, Spigelman I.

Neuropharmacology. 2018 Sep 1;139:85-97. doi: 10.1016/j.neuropharm.2018.07.002. Epub 2018 Jul 5.


TNFα in the Trigeminal Nociceptive System Is Critical for Temporomandibular Joint Pain.

Bai Q, Liu S, Shu H, Tang Y, George S, Dong T, Schmidt BL, Tao F.

Mol Neurobiol. 2019 Jan;56(1):278-291. doi: 10.1007/s12035-018-1076-y. Epub 2018 Apr 25.


Dental disease before radiotherapy in patients with head and neck cancer: Clinical Registry of Dental Outcomes in Head and Neck Cancer Patients.

Brennan MT, Treister NS, Sollecito TP, Schmidt BL, Patton LL, Mohammadi K, Long Simpson L, Voelker H, Hodges JS, Lalla RV.

J Am Dent Assoc. 2017 Dec;148(12):868-877. doi: 10.1016/j.adaj.2017.09.011. Erratum in: J Am Dent Assoc. 2018 Feb;149(2):89.


Tumor necrosis factor alpha secreted from oral squamous cell carcinoma contributes to cancer pain and associated inflammation.

Scheff NN, Ye Y, Bhattacharya A, MacRae J, Hickman DN, Sharma AK, Dolan JC, Schmidt BL.

Pain. 2017 Dec;158(12):2396-2409. doi: 10.1097/j.pain.0000000000001044.


Cutaneous pigmentation modulates skin sensitivity via tyrosinase-dependent dopaminergic signalling.

Ono K, Viet CT, Ye Y, Dang D, Hitomi S, Toyono T, Inenaga K, Dolan JC, Schmidt BL.

Sci Rep. 2017 Aug 23;7(1):9181. doi: 10.1038/s41598-017-09682-4.


Alterations in opioid inhibition cause widespread nociception but do not affect anxiety-like behavior in oral cancer mice.

Ye Y, Bernabé DG, Salvo E, Viet CT, Ono K, Dolan JC, Janal M, Aouizerat BE, Miaskowski C, Schmidt BL.

Neuroscience. 2017 Nov 5;363:50-61. doi: 10.1016/j.neuroscience.2017.06.038. Epub 2017 Jun 30.


OPRM1 Methylation Contributes to Opioid Tolerance in Cancer Patients.

Viet CT, Dang D, Aouizerat BE, Miaskowski C, Ye Y, Viet DT, Ono K, Schmidt BL.

J Pain. 2017 Sep;18(9):1046-1059. doi: 10.1016/j.jpain.2017.04.001. Epub 2017 Apr 27.


Ex vivo nonviral gene delivery of μ-opioid receptor to attenuate cancer-induced pain.

Yamano S, Viet CT, Dang D, Dai J, Hanatani S, Takayama T, Kasai H, Imamura K, Campbell R, Ye Y, Dolan JC, Kwon WM, Schneider SD, Schmidt BL.

Pain. 2017 Feb;158(2):240-251. doi: 10.1097/j.pain.0000000000000750.


Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial.

Ross S, Bossis A, Guss J, Agin-Liebes G, Malone T, Cohen B, Mennenga SE, Belser A, Kalliontzi K, Babb J, Su Z, Corby P, Schmidt BL.

J Psychopharmacol. 2016 Dec;30(12):1165-1180.


Piphillin: Improved Prediction of Metagenomic Content by Direct Inference from Human Microbiomes.

Iwai S, Weinmaier T, Schmidt BL, Albertson DG, Poloso NJ, Dabbagh K, DeSantis TZ.

PLoS One. 2016 Nov 7;11(11):e0166104. doi: 10.1371/journal.pone.0166104. eCollection 2016.


Oral mucosal injury caused by mammalian target of rapamycin inhibitors: emerging perspectives on pathobiology and impact on clinical practice.

Peterson DE, O'Shaughnessy JA, Rugo HS, Elad S, Schubert MM, Viet CT, Campbell-Baird C, Hronek J, Seery V, Divers J, Glaspy J, Schmidt BL, Meiller TF.

Cancer Med. 2016 Aug;5(8):1897-907. doi: 10.1002/cam4.761. Epub 2016 Jun 23. Review.


Canola Oil in Lactating Dairy Cow Diets Reduces Milk Saturated Fatty Acids and Improves Its Omega-3 and Oleic Fatty Acid Content.

Welter KC, Martins CM, de Palma AS, Martins MM, Dos Reis BR, Schmidt BL, Saran Netto A.

PLoS One. 2016 Mar 25;11(3):e0151876. doi: 10.1371/journal.pone.0151876. eCollection 2016.


Gene Expression Profiling of Evening Fatigue in Women Undergoing Chemotherapy for Breast Cancer.

Kober KM, Dunn L, Mastick J, Cooper B, Langford D, Melisko M, Venook A, Chen LM, Wright F, Hammer M, Schmidt BL, Levine J, Miaskowski C, Aouizerat BE.

Biol Res Nurs. 2016 Jul;18(4):370-85. doi: 10.1177/1099800416629209. Epub 2016 Mar 8.


RAF Kinase Inhibitory Protein Expression and Phosphorylation Profiles in Oral Cancers.

Hallums DP, Gomez R, Doyle AP, Viet CT, Schmidt BL, Jeske NA.

Clin Surg. 2016;1. pii: 1100. Epub 2016 Sep 1.


Structural and functional interactions between six-transmembrane μ-opioid receptors and β2-adrenoreceptors modulate opioid signaling.

Samoshkin A, Convertino M, Viet CT, Wieskopf JS, Kambur O, Marcovitz J, Patel P, Stone LS, Kalso E, Mogil JS, Schmidt BL, Maixner W, Dokholyan NV, Diatchenko L.

Sci Rep. 2015 Dec 11;5:18198. doi: 10.1038/srep18198.


The Neurobiology of Cancer Pain.

Schmidt BL.

J Oral Maxillofac Surg. 2015 Dec;73(12 Suppl):S132-5. doi: 10.1016/j.joms.2015.04.045. Review.


Differential Regulation of 6- and 7-Transmembrane Helix Variants of μ-Opioid Receptor in Response to Morphine Stimulation.

Convertino M, Samoshkin A, Viet CT, Gauthier J, Li Fraine SP, Sharif-Naeini R, Schmidt BL, Maixner W, Diatchenko L, Dokholyan NV.

PLoS One. 2015 Nov 10;10(11):e0142826. doi: 10.1371/journal.pone.0142826. eCollection 2015.


Conditional TNF-α Overexpression in the Tooth and Alveolar Bone Results in Painful Pulpitis and Osteitis.

Hall BE, Zhang L, Sun ZJ, Utreras E, Prochazkova M, Cho A, Terse A, Arany P, Dolan JC, Schmidt BL, Kulkarni AB.

J Dent Res. 2016 Feb;95(2):188-95. doi: 10.1177/0022034515612022. Epub 2015 Oct 26.


Glycosylated Hemoglobin A1c and Lack of Association With Symptom Severity in Patients Undergoing Chemotherapy for Solid Tumors.

Hammer MJ, Aouizerat BE, Schmidt BL, Cartwright F, Wright F, Miaskowski C.

Oncol Nurs Forum. 2015 Nov;42(6):581-90. doi: 10.1188/15.ONF.581-590.


Dietary Supplementation in Children with Autism Spectrum Disorders: Common, Insufficient, and Excessive.

Stewart PA, Hyman SL, Schmidt BL, Macklin EA, Reynolds A, Johnson CR, James SJ, Manning-Courtney P.

J Acad Nutr Diet. 2015 Aug;115(8):1237-48. doi: 10.1016/j.jand.2015.03.026. Epub 2015 Jun 4.


Trajectories of Evening Fatigue in Oncology Outpatients Receiving Chemotherapy.

Wright F, D'Eramo Melkus G, Hammer M, Schmidt BL, Knobf MT, Paul SM, Cartwright F, Mastick J, Cooper BA, Chen LM, Melisko M, Levine JD, Kober K, Aouizerat BE, Miaskowski C.

J Pain Symptom Manage. 2015 Aug;50(2):163-75. doi: 10.1016/j.jpainsymman.2015.02.015. Epub 2015 Mar 28.


Predictors and Trajectories of Morning Fatigue Are Distinct From Evening Fatigue.

Wright F, D'Eramo Melkus G, Hammer M, Schmidt BL, Knobf MT, Paul SM, Cartwright F, Mastick J, Cooper BA, Chen LM, Melisko M, Levine JD, Kober K, Aouizerat BE, Miaskowski C.

J Pain Symptom Manage. 2015 Aug;50(2):176-89. doi: 10.1016/j.jpainsymman.2015.02.016. Epub 2015 Mar 28.


What pain tells us about cancer.

Schmidt BL.

Pain. 2015 Apr;156 Suppl 1:S32-4. doi: 10.1097/j.pain.0000000000000099. Review.


TRPV1 expression level in isolectin B₄-positive neurons contributes to mouse strain difference in cutaneous thermal nociceptive sensitivity.

Ono K, Ye Y, Viet CT, Dang D, Schmidt BL.

J Neurophysiol. 2015 May 1;113(9):3345-55. doi: 10.1152/jn.00973.2014. Epub 2015 Mar 18.


TMPRSS2, a novel membrane-anchored mediator in cancer pain.

Lam DK, Dang D, Flynn AN, Hardt M, Schmidt BL.

Pain. 2015 May;156(5):923-30. doi: 10.1097/j.pain.0000000000000130.


Persistent breast pain following breast cancer surgery is associated with persistent sensory changes, pain interference, and functional impairments.

Langford DJ, Paul SM, West C, Levine JD, Hamolsky D, Elboim C, Schmidt BL, Cooper BA, Abrams G, Aouizerat BE, Miaskowski C.

J Pain. 2014 Dec;15(12):1227-37. doi: 10.1016/j.jpain.2014.08.014.


Decitabine rescues cisplatin resistance in head and neck squamous cell carcinoma.

Viet CT, Dang D, Achdjian S, Ye Y, Katz SG, Schmidt BL.

PLoS One. 2014 Nov 12;9(11):e112880. doi: 10.1371/journal.pone.0112880. eCollection 2014.


Demethylating drugs as novel analgesics for cancer pain.

Viet CT, Dang D, Ye Y, Ono K, Campbell RR, Schmidt BL.

Clin Cancer Res. 2014 Sep 15;20(18):4882-4893. doi: 10.1158/1078-0432.CCR-14-0901. Epub 2014 Jun 24.


Review of preclinical studies on treatment of mucositis and associated pain.

Viet CT, Corby PM, Akinwande A, Schmidt BL.

J Dent Res. 2014 Sep;93(9):868-75. doi: 10.1177/0022034514540174. Epub 2014 Jun 18. Review.


Adenosine triphosphate drives head and neck cancer pain through P2X2/3 heterotrimers.

Ye Y, Ono K, Bernabé DG, Viet CT, Pickering V, Dolan JC, Hardt M, Ford AP, Schmidt BL.

Acta Neuropathol Commun. 2014 Jun 5;2:62. doi: 10.1186/2051-5960-2-62.


Changes in abundance of oral microbiota associated with oral cancer.

Schmidt BL, Kuczynski J, Bhattacharya A, Huey B, Corby PM, Queiroz EL, Nightingale K, Kerr AR, DeLacure MD, Veeramachaneni R, Olshen AB, Albertson DG.

PLoS One. 2014 Jun 2;9(6):e98741. doi: 10.1371/journal.pone.0098741. eCollection 2014. Erratum in: PLoS One. 2014;9(8):e106297. Muy-Teck The [removed].


Investigation of HOXA9 promoter methylation as a biomarker to distinguish oral cancer patients at low risk of neck metastasis.

Uchida K, Veeramachaneni R, Huey B, Bhattacharya A, Schmidt BL, Albertson DG.

BMC Cancer. 2014 May 21;14:353. doi: 10.1186/1471-2407-14-353.


Disease and treatment characteristics do not predict symptom occurrence profiles in oncology outpatients receiving chemotherapy.

Miaskowski C, Cooper BA, Melisko M, Chen LM, Mastick J, West C, Paul SM, Dunn LB, Schmidt BL, Hammer M, Cartwright F, Wright F, Langford DJ, Lee K, Aouizerat BE.

Cancer. 2014 Aug 1;120(15):2371-8. doi: 10.1002/cncr.28699. Epub 2014 May 2.


The neurobiology of cancer pain.

Schmidt BL.

Neuroscientist. 2014 Oct;20(5):546-62. doi: 10.1177/1073858414525828. Epub 2014 Mar 24. Review.


IB4(+) and TRPV1(+) sensory neurons mediate pain but not proliferation in a mouse model of squamous cell carcinoma.

Ye Y, Bae SS, Viet CT, Troob S, Bernabé D, Schmidt BL.

Behav Brain Funct. 2014 Feb 13;10:5. doi: 10.1186/1744-9081-10-5.


Cytokine candidate genes predict the development of secondary lymphedema following breast cancer surgery.

Leung G, Baggott C, West C, Elboim C, Paul SM, Cooper BA, Abrams G, Dhruva A, Schmidt BL, Kober K, Merriman JD, Leutwyler H, Neuhaus J, Langford D, Smoot BJ, Aouizerat BE, Miaskowski C.

Lymphat Res Biol. 2014 Mar;12(1):10-22. doi: 10.1089/lrb.2013.0024. Epub 2014 Feb 6.


Associations between cytokine gene variations and severe persistent breast pain in women following breast cancer surgery.

Stephens K, Cooper BA, West C, Paul SM, Baggott CR, Merriman JD, Dhruva A, Kober KM, Langford DJ, Leutwyler H, Luce JA, Schmidt BL, Abrams GM, Elboim C, Hamolsky D, Levine JD, Miaskowski C, Aouizerat BE.

J Pain. 2014 Feb;15(2):169-80. doi: 10.1016/j.jpain.2013.09.015. Epub 2013 Oct 12.


Variations in potassium channel genes are associated with breast pain in women prior to breast cancer surgery.

Langford DJ, West C, Elboim C, Cooper BA, Abrams G, Paul SM, Schmidt BL, Levine JD, Merriman JD, Dhruva A, Neuhaus J, Leutwyler H, Baggott C, Sullivan CW, Aouizerat BE, Miaskowski C.

J Neurogenet. 2014 Mar-Jun;28(1-2):122-35. doi: 10.3109/01677063.2013.856430. Epub 2014 Jan 7.


Lymphatic and angiogenic candidate genes predict the development of secondary lymphedema following breast cancer surgery.

Miaskowski C, Dodd M, Paul SM, West C, Hamolsky D, Abrams G, Cooper BA, Elboim C, Neuhaus J, Schmidt BL, Smoot B, Aouizerat BE.

PLoS One. 2013 Apr 16;8(4):e60164. doi: 10.1371/journal.pone.0060164. Print 2013.

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