Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 20

1.

G protein signaling-biased agonism at the κ-opioid receptor is maintained in striatal neurons.

Ho JH, Stahl EL, Schmid CL, Scarry SM, Aubé J, Bohn LM.

Sci Signal. 2018 Aug 7;11(542). pii: eaar4309. doi: 10.1126/scisignal.aar4309.

PMID:
30087177
2.

Dynamic Strategic Bond Analysis Yields a Ten-Step Synthesis of 20-nor-Salvinorin A, a Potent κ-OR Agonist.

Roach JJ, Sasano Y, Schmid CL, Zaidi S, Katritch V, Stevens RC, Bohn LM, Shenvi RA.

ACS Cent Sci. 2017 Dec 27;3(12):1329-1336. doi: 10.1021/acscentsci.7b00488. Epub 2017 Dec 13.

3.

Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics.

Schmid CL, Kennedy NM, Ross NC, Lovell KM, Yue Z, Morgenweck J, Cameron MD, Bannister TD, Bohn LM.

Cell. 2017 Nov 16;171(5):1165-1175.e13. doi: 10.1016/j.cell.2017.10.035.

PMID:
29149605
4.

Stolonidiol: Synthesis, Target Identification, and Mechanism for Choline Acetyltransferase Activation.

Mason JW, Schmid CL, Bohn LM, Roush WR.

J Am Chem Soc. 2017 Apr 26;139(16):5865-5869. doi: 10.1021/jacs.7b01083. Epub 2017 Apr 17.

PMID:
28414442
5.

Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria.

Brust TF, Morgenweck J, Kim SA, Rose JH, Locke JL, Schmid CL, Zhou L, Stahl EL, Cameron MD, Scarry SM, Aubé J, Jones SR, Martin TJ, Bohn LM.

Sci Signal. 2016 Nov 29;9(456):ra117.

6.

Recruitment of β-Arrestin into Neuronal Cilia Modulates Somatostatin Receptor Subtype 3 Ciliary Localization.

Green JA, Schmid CL, Bley E, Monsma PC, Brown A, Bohn LM, Mykytyn K.

Mol Cell Biol. 2015 Oct 26;36(1):223-35. doi: 10.1128/MCB.00765-15. Print 2016 Jan 1.

7.

Clozapine acts as an agonist at serotonin 2A receptors to counter MK-801-induced behaviors through a βarrestin2-independent activation of Akt.

Schmid CL, Streicher JM, Meltzer HY, Bohn LM.

Neuropsychopharmacology. 2014 Jul;39(8):1902-13. doi: 10.1038/npp.2014.38. Epub 2014 Feb 17.

8.

Development of functionally selective, small molecule agonists at kappa opioid receptors.

Zhou L, Lovell KM, Frankowski KJ, Slauson SR, Phillips AM, Streicher JM, Stahl E, Schmid CL, Hodder P, Madoux F, Cameron MD, Prisinzano TE, Aubé J, Bohn LM.

J Biol Chem. 2013 Dec 20;288(51):36703-16. doi: 10.1074/jbc.M113.504381. Epub 2013 Nov 1.

9.

Functional selectivity of 6'-guanidinonaltrindole (6'-GNTI) at κ-opioid receptors in striatal neurons.

Schmid CL, Streicher JM, Groer CE, Munro TA, Zhou L, Bohn LM.

J Biol Chem. 2013 Aug 2;288(31):22387-98. doi: 10.1074/jbc.M113.476234. Epub 2013 Jun 17.

10.

Prometheus: the Supreme Court redefines the patentability of diagnostic inventions.

Kumamoto A, Schmid CL.

Recent Pat DNA Gene Seq. 2012 Dec;6(3):193-6.

PMID:
22812581
11.

β-arrestin2 regulates cannabinoid CB1 receptor signaling and adaptation in a central nervous system region-dependent manner.

Nguyen PT, Schmid CL, Raehal KM, Selley DE, Bohn LM, Sim-Selley LJ.

Biol Psychiatry. 2012 Apr 15;71(8):714-24. doi: 10.1016/j.biopsych.2011.11.027. Epub 2012 Jan 20.

12.

Functional selectivity at the μ-opioid receptor: implications for understanding opioid analgesia and tolerance.

Raehal KM, Schmid CL, Groer CE, Bohn LM.

Pharmacol Rev. 2011 Dec;63(4):1001-19. doi: 10.1124/pr.111.004598. Epub 2011 Aug 26. Review.

13.

Agonist-directed interactions with specific beta-arrestins determine mu-opioid receptor trafficking, ubiquitination, and dephosphorylation.

Groer CE, Schmid CL, Jaeger AM, Bohn LM.

J Biol Chem. 2011 Sep 9;286(36):31731-41. doi: 10.1074/jbc.M111.248310. Epub 2011 Jul 14.

14.

Serotonin, but not N-methyltryptamines, activates the serotonin 2A receptor via a ß-arrestin2/Src/Akt signaling complex in vivo.

Schmid CL, Bohn LM.

J Neurosci. 2010 Oct 6;30(40):13513-24. doi: 10.1523/JNEUROSCI.1665-10.2010.

15.

Serotonin receptor signaling and regulation via β-arrestins.

Bohn LM, Schmid CL.

Crit Rev Biochem Mol Biol. 2010 Dec;45(6):555-66. doi: 10.3109/10409238.2010.516741. Epub 2010 Oct 7. Review.

16.

Lubiprostone reverses the inhibitory action of morphine on intestinal secretion in guinea pig and mouse.

Fei G, Raehal K, Liu S, Qu MH, Sun X, Wang GD, Wang XY, Xia Y, Schmid CL, Bohn LM, Wood JD.

J Pharmacol Exp Ther. 2010 Jul;334(1):333-40. doi: 10.1124/jpet.110.166116. Epub 2010 Apr 20.

17.

Morphine-induced physiological and behavioral responses in mice lacking G protein-coupled receptor kinase 6.

Raehal KM, Schmid CL, Medvedev IO, Gainetdinov RR, Premont RT, Bohn LM.

Drug Alcohol Depend. 2009 Oct 1;104(3):187-96. doi: 10.1016/j.drugalcdep.2009.04.011. Epub 2009 Jun 3.

18.

Physiological and pharmacological implications of beta-arrestin regulation.

Schmid CL, Bohn LM.

Pharmacol Ther. 2009 Mar;121(3):285-93. doi: 10.1016/j.pharmthera.2008.11.005. Epub 2008 Dec 6. Review.

19.

Agonist-directed signaling of the serotonin 2A receptor depends on beta-arrestin-2 interactions in vivo.

Schmid CL, Raehal KM, Bohn LM.

Proc Natl Acad Sci U S A. 2008 Jan 22;105(3):1079-84. doi: 10.1073/pnas.0708862105. Epub 2008 Jan 14.

20.

Intermolecular interactions between retroviral Gag proteins in the nucleus.

Kenney SP, Lochmann TL, Schmid CL, Parent LJ.

J Virol. 2008 Jan;82(2):683-91. Epub 2007 Oct 31.

Supplemental Content

Loading ...
Support Center