Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 58

1.

Fluid shear stress impacts ovarian cancer cell viability, subcellular organization, and promotes genomic instability.

Hyler AR, Baudoin NC, Brown MS, Stremler MA, Cimini D, Davalos RV, Schmelz EM.

PLoS One. 2018 Mar 22;13(3):e0194170. doi: 10.1371/journal.pone.0194170. eCollection 2018.

2.

High-frequency irreversible electroporation targets resilient tumor-initiating cells in ovarian cancer.

Rolong A, Schmelz EM, Davalos RV.

Integr Biol (Camb). 2017 Dec 11;9(12):979-987. doi: 10.1039/c7ib00116a.

PMID:
29186222
3.

N-(3-oxododecanoyl)-L-homoserine lactone interactions in the breast tumor microenvironment: Implications for breast cancer viability and proliferation in vitro.

Balhouse BN, Patterson L, Schmelz EM, Slade DJ, Verbridge SS.

PLoS One. 2017 Jul 10;12(7):e0180372. doi: 10.1371/journal.pone.0180372. eCollection 2017.

4.

A feasibility study for enrichment of highly aggressive cancer subpopulations by their biophysical properties via dielectrophoresis enhanced with synergistic fluid flow.

Douglas TA, Cemazar J, Balani N, Sweeney DC, Schmelz EM, Davalos RV.

Electrophoresis. 2017 Jun;38(11):1507-1514. doi: 10.1002/elps.201600530. Epub 2017 May 8.

5.

Coordinated Upregulation of Mitochondrial Biogenesis and Autophagy in Breast Cancer Cells: The Role of Dynamin Related Protein-1 and Implication for Breast Cancer Treatment.

Zou P, Liu L, Zheng LD, Payne KK, Manjili MH, Idowu MO, Zhang J, Schmelz EM, Cheng Z.

Oxid Med Cell Longev. 2016;2016:4085727. Epub 2016 Sep 26.

6.

Alternating electric fields (TTFields) in combination with paclitaxel are therapeutically effective against ovarian cancer cells in vitro and in vivo.

Voloshin T, Munster M, Blatt R, Shteingauz A, Roberts PC, Schmelz EM, Giladi M, Schneiderman RS, Zeevi E, Porat Y, Bomzon Z, Urman N, Itzhaki A, Cahal S, Kirson ED, Weinberg U, Palti Y.

Int J Cancer. 2016 Dec 15;139(12):2850-2858. doi: 10.1002/ijc.30406. Epub 2016 Sep 19.

7.

Enhanced contactless dielectrophoresis enrichment and isolation platform via cell-scale microstructures.

Čemažar J, Douglas TA, Schmelz EM, Davalos RV.

Biomicrofluidics. 2016 Jan 19;10(1):014109. doi: 10.1063/1.4939947. eCollection 2016 Jan.

8.

Interleukin-12 Immunomodulation Delays the Onset of Lethal Peritoneal Disease of Ovarian Cancer.

Cohen CA, Shea AA, Heffron CL, Schmelz EM, Roberts PC.

J Interferon Cytokine Res. 2016 Jan;36(1):62-73. doi: 10.1089/jir.2015.0049. Epub 2015 Oct 2.

9.

Ovarian tumor-initiating cells display a flexible metabolism.

Anderson AS, Roberts PC, Frisard MI, Hulver MW, Schmelz EM.

Exp Cell Res. 2014 Oct 15;328(1):44-57. doi: 10.1016/j.yexcr.2014.08.028. Epub 2014 Aug 27.

10.

Targeting mitochondrial alterations to prevent type 2 diabetes--evidence from studies of dietary redox-active compounds.

Cheng Z, Schmelz EM, Liu D, Hulver MW.

Mol Nutr Food Res. 2014 Aug;58(8):1739-49. doi: 10.1002/mnfr.201300747. Epub 2014 Feb 12. Review.

PMID:
24668725
11.

Biomechanical profile of cancer stem-like/tumor-initiating cells derived from a progressive ovarian cancer model.

Babahosseini H, Ketene AN, Schmelz EM, Roberts PC, Agah M.

Nanomedicine. 2014 Jul;10(5):1013-9. doi: 10.1016/j.nano.2013.12.009. Epub 2014 Jan 6.

12.

Investigating dielectric properties of different stages of syngeneic murine ovarian cancer cells.

Salmanzadeh A, Sano MB, Gallo-Villanueva RC, Roberts PC, Schmelz EM, Davalos RV.

Biomicrofluidics. 2013 Jan 23;7(1):11809. doi: 10.1063/1.4788921. eCollection 2013.

13.

Bioactive sphingolipid metabolites modulate ovarian cancer cell structural mechanics.

Babahosseini H, Roberts PC, Schmelz EM, Agah M.

Integr Biol (Camb). 2013 Nov;5(11):1385-92. doi: 10.1039/c3ib40121a. Epub 2013 Sep 20.

14.

The parity-associated microenvironmental niche in the omental fat band is refractory to ovarian cancer metastasis.

Cohen CA, Shea AA, Heffron CL, Schmelz EM, Roberts PC.

Cancer Prev Res (Phila). 2013 Nov;6(11):1182-93. doi: 10.1158/1940-6207.CAPR-13-0227. Epub 2013 Sep 10.

15.

In vitro model of spontaneous mouse OSE transformation.

Roberts PC, Schmelz EM.

Methods Mol Biol. 2013;1049:393-408. doi: 10.1007/978-1-62703-547-7_30.

PMID:
23913233
16.

Intra-abdominal fat depots represent distinct immunomodulatory microenvironments: a murine model.

Cohen CA, Shea AA, Heffron CL, Schmelz EM, Roberts PC.

PLoS One. 2013 Jun 12;8(6):e66477. doi: 10.1371/journal.pone.0066477. Print 2013.

17.

Sphingolipid metabolites modulate dielectric characteristics of cells in a mouse ovarian cancer progression model.

Salmanzadeh A, Elvington ES, Roberts PC, Schmelz EM, Davalos RV.

Integr Biol (Camb). 2013 Jun;5(6):843-52. doi: 10.1039/c3ib00008g.

18.

Metabolic changes during ovarian cancer progression as targets for sphingosine treatment.

Anderson AS, Roberts PC, Frisard MI, McMillan RP, Brown TJ, Lawless MH, Hulver MW, Schmelz EM.

Exp Cell Res. 2013 Jun 10;319(10):1431-42. doi: 10.1016/j.yexcr.2013.02.017. Epub 2013 Mar 19.

19.

Roles of bioactive sphingolipid metabolites in ovarian cancer cell biomechanics.

Babahosseini H, Roberts PC, Schmelz EM, Agah M.

Conf Proc IEEE Eng Med Biol Soc. 2012;2012:2436-9. doi: 10.1109/EMBC.2012.6346456.

PMID:
23366417
20.

Regulation of cytoskeleton organization by sphingosine in a mouse cell model of progressive ovarian cancer.

Creekmore AL, Heffron CL, Brayfield BP, Roberts PC, Schmelz EM.

Biomolecules. 2013 Jul 16;3(3):386-407. doi: 10.3390/biom3030386.

21.

Dielectrophoretic differentiation of mouse ovarian surface epithelial cells, macrophages, and fibroblasts using contactless dielectrophoresis.

Salmanzadeh A, Kittur H, Sano MB, C Roberts P, Schmelz EM, Davalos RV.

Biomicrofluidics. 2012 Jun;6(2):24104-2410413. doi: 10.1063/1.3699973. Epub 2012 Apr 3.

22.

Actin filaments play a primary role for structural integrity and viscoelastic response in cells.

Ketene AN, Roberts PC, Shea AA, Schmelz EM, Agah M.

Integr Biol (Camb). 2012 May;4(5):540-9. doi: 10.1039/c2ib00168c. Epub 2012 Mar 26.

PMID:
22446682
23.

Selective concentration of human cancer cells using contactless dielectrophoresis.

Henslee EA, Sano MB, Rojas AD, Schmelz EM, Davalos RV.

Electrophoresis. 2011 Sep;32(18):2523-9. doi: 10.1002/elps.201100081. Epub 2011 Aug 26.

PMID:
21922494
24.

Selective growth inhibition of human breast cancer cells by graviola fruit extract in vitro and in vivo involving downregulation of EGFR expression.

Dai Y, Hogan S, Schmelz EM, Ju YH, Canning C, Zhou K.

Nutr Cancer. 2011;63(5):795-801. doi: 10.1080/01635581.2011.563027. Epub 2011 Jun 22.

PMID:
21767082
25.

MCF10A and MDA-MB-231 human breast basal epithelial cell co-culture in silicon micro-arrays.

Nikkhah M, Strobl JS, Schmelz EM, Roberts PC, Zhou H, Agah M.

Biomaterials. 2011 Oct;32(30):7625-32. doi: 10.1016/j.biomaterials.2011.06.041. Epub 2011 Jul 18.

PMID:
21764441
26.

The effects of cancer progression on the viscoelasticity of ovarian cell cytoskeleton structures.

Ketene AN, Schmelz EM, Roberts PC, Agah M.

Nanomedicine. 2012 Jan;8(1):93-102. doi: 10.1016/j.nano.2011.05.012. Epub 2011 Jun 23. Erratum in: Nanomedicine. 2012 Apr;8(3):391.

PMID:
21704191
27.

Changes in gene expression and cellular architecture in an ovarian cancer progression model.

Creekmore AL, Silkworth WT, Cimini D, Jensen RV, Roberts PC, Schmelz EM.

PLoS One. 2011 Mar 3;6(3):e17676. doi: 10.1371/journal.pone.0017676.

28.

Suppression of intestinal inflammation and inflammation-driven colon cancer in mice by dietary sphingomyelin: importance of peroxisome proliferator-activated receptor γ expression.

Mazzei JC, Zhou H, Brayfield BP, Hontecillas R, Bassaganya-Riera J, Schmelz EM.

J Nutr Biochem. 2011 Dec;22(12):1160-71. doi: 10.1016/j.jnutbio.2010.09.017. Epub 2011 Feb 4.

29.

Evaluation of the influence of growth medium composition on cell elasticity.

Nikkhah M, Strobl JS, Schmelz EM, Agah M.

J Biomech. 2011 Feb 24;44(4):762-6. doi: 10.1016/j.jbiomech.2010.11.002. Epub 2010 Nov 24.

PMID:
21109247
30.

Folate deficiency provides protection against colon carcinogenesis in DNA polymerase beta haploinsufficient mice.

Ventrella-Lucente LF, Unnikrishnan A, Pilling AB, Patel HV, Kushwaha D, Dombkowski AA, Schmelz EM, Cabelof DC, Heydari AR.

J Biol Chem. 2010 Jun 18;285(25):19246-58. doi: 10.1074/jbc.M109.069807. Epub 2010 Apr 19.

31.

Conjugated linoleic acid ameliorates inflammation-induced colorectal cancer in mice through activation of PPARgamma.

Evans NP, Misyak SA, Schmelz EM, Guri AJ, Hontecillas R, Bassaganya-Riera J.

J Nutr. 2010 Mar;140(3):515-21. doi: 10.3945/jn.109.115642. Epub 2010 Jan 20.

32.

Suppression of breast xenograft growth and progression in nude mice: implications for the use of orally administered sphingolipids as chemopreventive agents against breast cancer.

Simon KW, Tait L, Miller F, Cao C, Davy KP, LeRoith T, Schmelz EM.

Food Funct. 2010 Oct;1(1):90-8. doi: 10.1039/c0fo00108b. Epub 2010 Sep 23.

PMID:
21776459
33.

Regulation of beta-catenin and connexin-43 expression: targets for sphingolipids in colon cancer prevention.

Simon KW, Roberts PC, Vespremi MJ, Manchen S, Schmelz EM.

Mol Nutr Food Res. 2009 Mar;53(3):332-40. doi: 10.1002/mnfr.200800102.

34.

Regression of early and intermediate stages of colon cancer by targeting multiple members of the EGFR family with EGFR-related protein.

Schmelz EM, Xu H, Sengupta R, Du J, Banerjee S, Sarkar FH, Rishi AK, Majumdar AP.

Cancer Res. 2007 Jun 1;67(11):5389-96.

35.

Sequential molecular and cellular events during neoplastic progression: a mouse syngeneic ovarian cancer model.

Roberts PC, Mottillo EP, Baxa AC, Heng HH, Doyon-Reale N, Gregoire L, Lancaster WD, Rabah R, Schmelz EM.

Neoplasia. 2005 Oct;7(10):944-56.

36.

Age-related loss of EGF-receptor related protein (ERRP) in the aging colon is a potential risk factor for colon cancer.

Schmelz EM, Levi E, Du J, Xu H, Majumdar AP.

Mech Ageing Dev. 2004 Dec;125(12):917-22.

PMID:
15563939
37.

Sphingolipids in the chemoprevention of colon cancer.

Schmelz EM.

Front Biosci. 2004 Sep 1;9:2632-9. Review.

PMID:
15358586
38.

Dietary soy sphingolipids suppress tumorigenesis and gene expression in 1,2-dimethylhydrazine-treated CF1 mice and ApcMin/+ mice.

Symolon H, Schmelz EM, Dillehay DL, Merrill AH Jr.

J Nutr. 2004 May;134(5):1157-61.

PMID:
15113963
39.

Relationship of socioeconomic status with cardiovascular risk factors and lifestyle in a Mediterranean population.

Schröder H, Rohlfs I, Schmelz EM, Marrugat J; REGICOR investigators.

Eur J Nutr. 2004 Apr;43(2):77-85. Epub 2004 Jan 6.

PMID:
15083314
40.

Sphingomyelin in the suppression of colon tumors: prevention versus intervention.

Lemonnier LA, Dillehay DL, Vespremi MJ, Abrams J, Brody E, Schmelz EM.

Arch Biochem Biophys. 2003 Nov 15;419(2):129-38.

PMID:
14592456
41.

Expression of EGF-receptor related protein (ERRP) decreases in gastric mucosa during aging and carcinogenesis.

Majumdar AP, Du J, Hatfield JS, Levi E, Adsay V, Schmelz EM, Nagothu KK, Jaszewski R, Kucuk O, Sarkar FH.

Dig Dis Sci. 2003 May;48(5):856-64.

PMID:
12772780
42.

Fumonisins and fumonisin analogs as inhibitors of ceramide synthase and inducers of apoptosis.

Desai K, Sullards MC, Allegood J, Wang E, Schmelz EM, Hartl M, Humpf HU, Liotta DC, Peng Q, Merrill AH Jr.

Biochim Biophys Acta. 2002 Dec 30;1585(2-3):188-92. Review.

PMID:
12531553
43.

Spontaneous malignant transformation of human ovarian surface epithelial cells in vitro.

Gregoire L, Rabah R, Schmelz EM, Munkarah A, Roberts PC, Lancaster WD.

Clin Cancer Res. 2001 Dec;7(12):4280-7.

44.

Modulation of intracellular beta-catenin localization and intestinal tumorigenesis in vivo and in vitro by sphingolipids.

Schmelz EM, Roberts PC, Kustin EM, Lemonnier LA, Sullards MC, Dillehay DL, Merrill AH Jr.

Cancer Res. 2001 Sep 15;61(18):6723-9.

45.

Regulation of cytochrome P450 expression by sphingolipids.

Merril AH Jr, Nikolova-Karakashian M, Schmelz EM, Morgan ET, Stewart J.

Chem Phys Lipids. 1999 Nov;102(1-2):131-9. Review.

PMID:
11001567
46.
47.

Ceramide-beta-D-glucuronide: synthesis, digestion, and suppression of early markers of colon carcinogenesis.

Schmelz EM, Bushnev AS, Dillehay DL, Sullards MC, Liotta DC, Merrill AH Jr.

Cancer Res. 1999 Nov 15;59(22):5768-72.

48.

Sphingolipids in food and the emerging importance of sphingolipids to nutrition.

Vesper H, Schmelz EM, Nikolova-Karakashian MN, Dillehay DL, Lynch DV, Merrill AH Jr.

J Nutr. 1999 Jul;129(7):1239-50. Review.

PMID:
10395583
49.

Ceramides and ceramide metabolites in cell regulation: evidence for dietary sphingolipids as inhibitors of colon carcinogenesis.

Schmelz EM, Merrill AH Jr.

Nutrition. 1998 Sep;14(9):717-9. No abstract available.

PMID:
9760598
50.

Supplemental Content

Loading ...
Support Center