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Items: 1 to 50 of 148


Characterization of sequentially-staged cancer cells using electrorotation.

Trainito CI, Sweeney DC, Čemažar J, Schmelz EM, Français O, Le Pioufle B, Davalos RV.

PLoS One. 2019 Sep 19;14(9):e0222289. doi: 10.1371/journal.pone.0222289. eCollection 2019.


Multiple genes recruited from hormone pathways partition maize diterpenoid defences.

Ding Y, Murphy KM, Poretsky E, Mafu S, Yang B, Char SN, Christensen SA, Saldivar E, Wu M, Wang Q, Ji L, Schmitz RJ, Kremling KA, Buckler ES, Shen Z, Briggs SP, Bohlmann J, Sher A, Castro-Falcon G, Hughes CC, Huffaker A, Zerbe P, Schmelz EA.

Nat Plants. 2019 Oct;5(10):1043-1056. doi: 10.1038/s41477-019-0509-6. Epub 2019 Sep 16.


Functional Characterization of Two Class II Diterpene Synthases Indicates Additional Specialized Diterpenoid Pathways in Maize (Zea mays).

Murphy KM, Ma LT, Ding Y, Schmelz EA, Zerbe P.

Front Plant Sci. 2018 Oct 23;9:1542. doi: 10.3389/fpls.2018.01542. eCollection 2018.


Ethylene signaling regulates natural variation in the abundance of antifungal acetylated diferuloylsucroses and Fusarium graminearum resistance in maize seedling roots.

Zhou S, Zhang YK, Kremling KA, Ding Y, Bennett JS, Bae JS, Kim DK, Ackerman HH, Kolomiets MV, Schmelz EA, Schroeder FC, Buckler ES, Jander G.

New Phytol. 2019 Mar;221(4):2096-2111. doi: 10.1111/nph.15520. Epub 2018 Nov 2.


Biosynthesis and function of terpenoid defense compounds in maize (Zea mays).

Block AK, Vaughan MM, Schmelz EA, Christensen SA.

Planta. 2019 Jan;249(1):21-30. doi: 10.1007/s00425-018-2999-2. Epub 2018 Sep 6. Review.


A fragmentation study of isoflavones by IT-TOF-MS using biosynthesized isotopes.

Nakata R, Yoshinaga N, Teraishi M, Okumoto Y, Huffaker A, Schmelz EA, Mori N.

Biosci Biotechnol Biochem. 2018 Aug;82(8):1309-1315. doi: 10.1080/09168451.2018.1465810. Epub 2018 Apr 26.


Fluid shear stress impacts ovarian cancer cell viability, subcellular organization, and promotes genomic instability.

Hyler AR, Baudoin NC, Brown MS, Stremler MA, Cimini D, Davalos RV, Schmelz EM.

PLoS One. 2018 Mar 22;13(3):e0194170. doi: 10.1371/journal.pone.0194170. eCollection 2018.


An apoplastic peptide activates salicylic acid signalling in maize.

Ziemann S, van der Linde K, Lahrmann U, Acar B, Kaschani F, Colby T, Kaiser M, Ding Y, Schmelz E, Huffaker A, Holton N, Zipfel C, Doehlemann G.

Nat Plants. 2018 Mar;4(3):172-180. doi: 10.1038/s41477-018-0116-y. Epub 2018 Feb 26.


Discovery, Biosynthesis and Stress-Related Accumulation of Dolabradiene-Derived Defenses in Maize.

Mafu S, Ding Y, Murphy KM, Yaacoobi O, Addison JB, Wang Q, Shen Z, Briggs SP, Bohlmann J, Castro-Falcon G, Hughes CC, Betsiashvili M, Huffaker A, Schmelz EA, Zerbe P.

Plant Physiol. 2018 Apr;176(4):2677-2690. doi: 10.1104/pp.17.01351. Epub 2018 Feb 23.


Commercial hybrids and mutant genotypes reveal complex protective roles for inducible terpenoid defenses in maize.

Christensen SA, Sims J, Vaughan MM, Hunter C, Block A, Willett D, Alborn HT, Huffaker A, Schmelz EA.

J Exp Bot. 2018 Mar 24;69(7):1693-1705. doi: 10.1093/jxb/erx495.


Fungal and herbivore elicitation of the novel maize sesquiterpenoid, zealexin A4, is attenuated by elevated CO2.

Christensen SA, Huffaker A, Sims J, Hunter CT, Block A, Vaughan MM, Willett D, Romero M, Mylroie JE, Williams WP, Schmelz EA.

Planta. 2018 Apr;247(4):863-873. doi: 10.1007/s00425-017-2830-5.


Fungal-induced protein hyperacetylation in maize identified by acetylome profiling.

Walley JW, Shen Z, McReynolds MR, Schmelz EA, Briggs SP.

Proc Natl Acad Sci U S A. 2018 Jan 2;115(1):210-215. doi: 10.1073/pnas.1717519115. Epub 2017 Dec 19.


High-frequency irreversible electroporation targets resilient tumor-initiating cells in ovarian cancer.

Rolong A, Schmelz EM, Davalos RV.

Integr Biol (Camb). 2017 Dec 11;9(12):979-987. doi: 10.1039/c7ib00116a.


Selinene Volatiles Are Essential Precursors for Maize Defense Promoting Fungal Pathogen Resistance.

Ding Y, Huffaker A, Köllner TG, Weckwerth P, Robert CAM, Spencer JL, Lipka AE, Schmelz EA.

Plant Physiol. 2017 Nov;175(3):1455-1468. doi: 10.1104/pp.17.00879. Epub 2017 Sep 20.


N-(3-oxododecanoyl)-L-homoserine lactone interactions in the breast tumor microenvironment: Implications for breast cancer viability and proliferation in vitro.

Balhouse BN, Patterson L, Schmelz EM, Slade DJ, Verbridge SS.

PLoS One. 2017 Jul 10;12(7):e0180372. doi: 10.1371/journal.pone.0180372. eCollection 2017.


A feasibility study for enrichment of highly aggressive cancer subpopulations by their biophysical properties via dielectrophoresis enhanced with synergistic fluid flow.

Douglas TA, Cemazar J, Balani N, Sweeney DC, Schmelz EM, Davalos RV.

Electrophoresis. 2017 Jun;38(11):1507-1514. doi: 10.1002/elps.201600530. Epub 2017 May 8.


Biosynthetic pathway of aliphatic formates via a Baeyer-Villiger oxidation in mechanism present in astigmatid mites.

Shimizu N, Sakata D, Schmelz EA, Mori N, Kuwahara Y.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2616-2621. doi: 10.1073/pnas.1612611114. Epub 2017 Feb 21.


Inducible De Novo Biosynthesis of Isoflavonoids in Soybean Leaves by Spodoptera litura Derived Elicitors: Tracer Techniques Aided by High Resolution LCMS.

Nakata R, Kimura Y, Aoki K, Yoshinaga N, Teraishi M, Okumoto Y, Huffaker A, Schmelz EA, Mori N.

J Chem Ecol. 2016 Dec;42(12):1226-1236. Epub 2016 Nov 8.


Coordinated Upregulation of Mitochondrial Biogenesis and Autophagy in Breast Cancer Cells: The Role of Dynamin Related Protein-1 and Implication for Breast Cancer Treatment.

Zou P, Liu L, Zheng LD, Payne KK, Manjili MH, Idowu MO, Zhang J, Schmelz EM, Cheng Z.

Oxid Med Cell Longev. 2016;2016:4085727. Epub 2016 Sep 26.


Alternating electric fields (TTFields) in combination with paclitaxel are therapeutically effective against ovarian cancer cells in vitro and in vivo.

Voloshin T, Munster M, Blatt R, Shteingauz A, Roberts PC, Schmelz EM, Giladi M, Schneiderman RS, Zeevi E, Porat Y, Bomzon Z, Urman N, Itzhaki A, Cahal S, Kirson ED, Weinberg U, Palti Y.

Int J Cancer. 2016 Dec 15;139(12):2850-2858. doi: 10.1002/ijc.30406. Epub 2016 Sep 19.


Interactive Effects of Elevated [CO2] and Drought on the Maize Phytochemical Defense Response against Mycotoxigenic Fusarium verticillioides.

Vaughan MM, Huffaker A, Schmelz EA, Dafoe NJ, Christensen SA, McAuslane HJ, Alborn HT, Allen LH, Teal PE.

PLoS One. 2016 Jul 13;11(7):e0159270. doi: 10.1371/journal.pone.0159270. eCollection 2016.


Activation of Shikimate, Phenylpropanoid, Oxylipins, and Auxin Pathways in Pectobacterium carotovorum Elicitors-Treated Moss.

Alvarez A, Montesano M, Schmelz E, Ponce de León I.

Front Plant Sci. 2016 Mar 22;7:328. doi: 10.3389/fpls.2016.00328. eCollection 2016.


Enhanced contactless dielectrophoresis enrichment and isolation platform via cell-scale microstructures.

Čemažar J, Douglas TA, Schmelz EM, Davalos RV.

Biomicrofluidics. 2016 Jan 19;10(1):014109. doi: 10.1063/1.4939947. eCollection 2016 Jan.


A maize death acid, 10-oxo-11-phytoenoic acid, is the predominant cyclopentenone signal present during multiple stress and developmental conditions.

Christensen SA, Huffaker A, Hunter CT, Alborn HT, Schmelz EA.

Plant Signal Behav. 2016;11(2):e1120395. doi: 10.1080/15592324.2015.1120395.


Interleukin-12 Immunomodulation Delays the Onset of Lethal Peritoneal Disease of Ovarian Cancer.

Cohen CA, Shea AA, Heffron CL, Schmelz EM, Roberts PC.

J Interferon Cytokine Res. 2016 Jan;36(1):62-73. doi: 10.1089/jir.2015.0049. Epub 2015 Oct 2.


Dynamic Maize Responses to Aphid Feeding Are Revealed by a Time Series of Transcriptomic and Metabolomic Assays.

Tzin V, Fernandez-Pozo N, Richter A, Schmelz EA, Schoettner M, Schäfer M, Ahern KR, Meihls LN, Kaur H, Huffaker A, Mori N, Degenhardt J, Mueller LA, Jander G.

Plant Physiol. 2015 Nov;169(3):1727-43. doi: 10.1104/pp.15.01039. Epub 2015 Sep 16.


Maize death acids, 9-lipoxygenase-derived cyclopente(a)nones, display activity as cytotoxic phytoalexins and transcriptional mediators.

Christensen SA, Huffaker A, Kaplan F, Sims J, Ziemann S, Doehlemann G, Ji L, Schmitz RJ, Kolomiets MV, Alborn HT, Mori N, Jander G, Ni X, Sartor RC, Byers S, Abdo Z, Schmelz EA.

Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):11407-12. doi: 10.1073/pnas.1511131112. Epub 2015 Aug 24.


Accumulation of terpenoid phytoalexins in maize roots is associated with drought tolerance.

Vaughan MM, Christensen S, Schmelz EA, Huffaker A, McAuslane HJ, Alborn HT, Romero M, Allen LH, Teal PE.

Plant Cell Environ. 2015 Nov;38(11):2195-207. doi: 10.1111/pce.12482. Epub 2015 Jan 23.


Accumulation of 5-hydroxynorvaline in maize (Zea mays) leaves is induced by insect feeding and abiotic stress.

Yan J, Lipka AE, Schmelz EA, Buckler ES, Jander G.

J Exp Bot. 2015 Feb;66(2):593-602. doi: 10.1093/jxb/eru385. Epub 2014 Sep 30.


Ovarian tumor-initiating cells display a flexible metabolism.

Anderson AS, Roberts PC, Frisard MI, Hulver MW, Schmelz EM.

Exp Cell Res. 2014 Oct 15;328(1):44-57. doi: 10.1016/j.yexcr.2014.08.028. Epub 2014 Aug 27.


The novel monocot-specific 9-lipoxygenase ZmLOX12 is required to mount an effective jasmonate-mediated defense against Fusarium verticillioides in maize.

Christensen SA, Nemchenko A, Park YS, Borrego E, Huang PC, Schmelz EA, Kunze S, Feussner I, Yalpani N, Meeley R, Kolomiets MV.

Mol Plant Microbe Interact. 2014 Nov;27(11):1263-76. doi: 10.1094/MPMI-06-13-0184-R.


Insect-induced daidzein, formononetin and their conjugates in soybean leaves.

Murakami S, Nakata R, Aboshi T, Yoshinaga N, Teraishi M, Okumoto Y, Ishihara A, Morisaka H, Huffaker A, Schmelz EA, Mori N.

Metabolites. 2014 Jul 4;4(3):532-46. doi: 10.3390/metabo4030532.


Influence of brown stink bug feeding, planting date and sampling time on common smut infection of maize.

Ni X, Toews MD, Buntin GD, Carpenter JE, Huffaker A, Schmelz EA, Cottrell TE, Abdo Z.

Insect Sci. 2014 Oct;21(5):564-71. doi: 10.1111/1744-7917.12149. Epub 2014 Aug 20.


Effects of elevated [CO2 ] on maize defence against mycotoxigenic Fusarium verticillioides.

Vaughan MM, Huffaker A, Schmelz EA, Dafoe NJ, Christensen S, Sims J, Martins VF, Swerbilow J, Romero M, Alborn HT, Allen LH, Teal PE.

Plant Cell Environ. 2014 Dec;37(12):2691-706. doi: 10.1111/pce.12337. Epub 2014 May 13.


Targeting mitochondrial alterations to prevent type 2 diabetes--evidence from studies of dietary redox-active compounds.

Cheng Z, Schmelz EM, Liu D, Hulver MW.

Mol Nutr Food Res. 2014 Aug;58(8):1739-49. doi: 10.1002/mnfr.201300747. Epub 2014 Feb 12. Review.


A 13-lipoxygenase, TomloxC, is essential for synthesis of C5 flavour volatiles in tomato.

Shen J, Tieman D, Jones JB, Taylor MG, Schmelz E, Huffaker A, Bies D, Chen K, Klee HJ.

J Exp Bot. 2014 Feb;65(2):419-28. doi: 10.1093/jxb/ert382. Epub 2014 Jan 22.


Biosynthesis, elicitation and roles of monocot terpenoid phytoalexins.

Schmelz EA, Huffaker A, Sims JW, Christensen SA, Lu X, Okada K, Peters RJ.

Plant J. 2014 Aug;79(4):659-78. doi: 10.1111/tpj.12436. Epub 2014 Mar 26. Review.


Biomechanical profile of cancer stem-like/tumor-initiating cells derived from a progressive ovarian cancer model.

Babahosseini H, Ketene AN, Schmelz EM, Roberts PC, Agah M.

Nanomedicine. 2014 Jul;10(5):1013-9. doi: 10.1016/j.nano.2013.12.009. Epub 2014 Jan 6.


Investigating dielectric properties of different stages of syngeneic murine ovarian cancer cells.

Salmanzadeh A, Sano MB, Gallo-Villanueva RC, Roberts PC, Schmelz EM, Davalos RV.

Biomicrofluidics. 2013 Jan 23;7(1):11809. doi: 10.1063/1.4788921. eCollection 2013.


Head-group acylation of monogalactosyldiacylglycerol is a common stress response, and the acyl-galactose acyl composition varies with the plant species and applied stress.

Vu HS, Roth MR, Tamura P, Samarakoon T, Shiva S, Honey S, Lowe K, Schmelz EA, Williams TD, Welti R.

Physiol Plant. 2014 Apr;150(4):517-28. doi: 10.1111/ppl.12132. Epub 2013 Dec 27.


Bioactive sphingolipid metabolites modulate ovarian cancer cell structural mechanics.

Babahosseini H, Roberts PC, Schmelz EM, Agah M.

Integr Biol (Camb). 2013 Nov;5(11):1385-92. doi: 10.1039/c3ib40121a. Epub 2013 Sep 20.


European corn borer (Ostrinia nubilalis) induced responses enhance susceptibility in maize.

Dafoe NJ, Thomas JD, Shirk PD, Legaspi ME, Vaughan MM, Huffaker A, Teal PE, Schmelz EA.

PLoS One. 2013 Sep 2;8(9):e73394. doi: 10.1371/journal.pone.0073394. eCollection 2013.


The parity-associated microenvironmental niche in the omental fat band is refractory to ovarian cancer metastasis.

Cohen CA, Shea AA, Heffron CL, Schmelz EM, Roberts PC.

Cancer Prev Res (Phila). 2013 Nov;6(11):1182-93. doi: 10.1158/1940-6207.CAPR-13-0227. Epub 2013 Sep 10.


Evaluation of spatial and temporal patterns of insect damage and aflatoxin level in the pre-harvest corn fields to improve management tactics.

Ni X, Wilson JP, Toews MD, Buntin GD, Lee RD, Li X, Lei Z, He K, Xu W, Li X, Huffaker A, Schmelz EA.

Insect Sci. 2014 Oct;21(5):572-83. doi: 10.1111/j.1744-7917.2012.01531.x. Epub 2012 Sep 3.


In vitro model of spontaneous mouse OSE transformation.

Roberts PC, Schmelz EM.

Methods Mol Biol. 2013;1049:393-408. doi: 10.1007/978-1-62703-547-7_30.


Intra-abdominal fat depots represent distinct immunomodulatory microenvironments: a murine model.

Cohen CA, Shea AA, Heffron CL, Schmelz EM, Roberts PC.

PLoS One. 2013 Jun 12;8(6):e66477. doi: 10.1371/journal.pone.0066477. Print 2013.


Sphingolipid metabolites modulate dielectric characteristics of cells in a mouse ovarian cancer progression model.

Salmanzadeh A, Elvington ES, Roberts PC, Schmelz EM, Davalos RV.

Integr Biol (Camb). 2013 Jun;5(6):843-52. doi: 10.1039/c3ib00008g.


Metabolic changes during ovarian cancer progression as targets for sphingosine treatment.

Anderson AS, Roberts PC, Frisard MI, McMillan RP, Brown TJ, Lawless MH, Hulver MW, Schmelz EM.

Exp Cell Res. 2013 Jun 10;319(10):1431-42. doi: 10.1016/j.yexcr.2013.02.017. Epub 2013 Mar 19.


Plant elicitor peptides are conserved signals regulating direct and indirect antiherbivore defense.

Huffaker A, Pearce G, Veyrat N, Erb M, Turlings TC, Sartor R, Shen Z, Briggs SP, Vaughan MM, Alborn HT, Teal PE, Schmelz EA.

Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5707-12. doi: 10.1073/pnas.1214668110. Epub 2013 Mar 18.


Roles of bioactive sphingolipid metabolites in ovarian cancer cell biomechanics.

Babahosseini H, Roberts PC, Schmelz EM, Agah M.

Conf Proc IEEE Eng Med Biol Soc. 2012;2012:2436-9. doi: 10.1109/EMBC.2012.6346456.


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