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Items: 1 to 50 of 173

1.

Use of Positron Emission Tomography and Other Neuroimaging Techniques in the Diagnosis and Management of Alzheimer’s Disease and Dementia [Internet].

Matchar DB, Kulasingam SL, McCrory DC, Patwardhan MB, Rutschmann OT, Samsa GP, Schmechel DE.

Rockville (MD): Agency for Healthcare Research and Quality (US); 2001 Dec 14.

2.

Emotional reactions to pain predict psychological distress in adult patients with Sickle Cell Disease (SCD).

Edwards CL, Killough A, Wood M, Doyle T, Feliu M, Barker CS, Uppal P, DeCastro L, Wellington C, Whitfield KE, O'Garo KG, Morgan K, Edwards Alesii LY, Byrd GS, McCabe M, Goli V, Keys A, Hill L, Collins-McNeil J, Trambadia J, Guinyard D, Muhammad M, McDonald P, Schmechel DE, Robinson E.

Int J Psychiatry Med. 2014;47(1):1-16.

3.

A double-blind, placebo-controlled, ascending-dose, randomized study to evaluate the safety, tolerability and effects on cognition of AL-108 after 12 weeks of intranasal administration in subjects with mild cognitive impairment.

Morimoto BH, Schmechel D, Hirman J, Blackwell A, Keith J, Gold M; AL-108-211 Study.

Dement Geriatr Cogn Disord. 2013;35(5-6):325-36. doi: 10.1159/000348347. Epub 2013 Apr 13.

PMID:
23594991
4.

Deficiency of α-1-antitrypsin influences systemic iron homeostasis.

Ghio AJ, Soukup JM, Richards JH, Fischer BM, Voynow JA, Schmechel DE.

Int J Chron Obstruct Pulmon Dis. 2013;8:45-51. doi: 10.2147/COPD.S37897. Epub 2013 Jan 22.

5.

A multi-center ring trial of allergen analysis using fluorescent multiplex array technology.

King EM, Filep S, Smith B, Platts-Mills T, Hamilton RG, Schmechel D, Sordillo JE, Milton D, van Ree R, Krop EJ, Heederik DJ, Metwali N, Thorne PS, Zeldin DC, Sever ML, Calatroni A, Arbes SJ Jr, Mitchell HE, Chapman MD.

J Immunol Methods. 2013 Jan 31;387(1-2):89-95. doi: 10.1016/j.jim.2012.09.015. Epub 2012 Oct 22.

6.

Creativity and mental disorder.

Schmechel DE.

Br J Psychiatry. 2012 Apr;200(4):347; author reply 348. doi: 10.1192/bjp.200.4.347. No abstract available.

PMID:
22474239
7.

Fibromyalgia, mood disorders, and intense creative energy: A1AT polymorphisms are not always silent.

Schmechel DE, Edwards CL.

Neurotoxicology. 2012 Dec;33(6):1454-72. doi: 10.1016/j.neuro.2012.03.001. Epub 2012 Mar 10.

PMID:
22414631
8.

Production, characterization and utility of a panel of monoclonal antibodies for the detection of toluene diisocyanate haptenated proteins.

Ruwona TB, Johnson VJ, Hettick JM, Schmechel D, Beezhold D, Wang W, Simoyi RH, Siegel PD.

J Immunol Methods. 2011 Oct 28;373(1-2):127-35. doi: 10.1016/j.jim.2011.08.011. Epub 2011 Aug 22.

PMID:
21878336
9.

Monoclonal antibodies to hyphal exoantigens derived from the opportunistic pathogen Aspergillus terreus.

Nayak AP, Green BJ, Janotka E, Hettick JM, Friend S, Vesper SJ, Schmechel D, Beezhold DH.

Clin Vaccine Immunol. 2011 Sep;18(9):1568-76. doi: 10.1128/CVI.05163-11. Epub 2011 Jul 6.

10.

Production and characterization of IgM monoclonal antibodies against hyphal antigens of Stachybotrys species.

Nayak AP, Green BJ, Janotka E, Blachere FM, Vesper SJ, Beezhold DH, Schmechel D.

Hybridoma (Larchmt). 2011 Feb;30(1):29-36. doi: 10.1089/hyb.2010.0071.

11.

Characterization of recombinant terrelysin, a hemolysin of Aspergillus terreus.

Nayak AP, Blachere FM, Hettick JM, Lukomski S, Schmechel D, Beezhold DH.

Mycopathologia. 2011 Jan;171(1):23-34. doi: 10.1007/s11046-010-9343-0. Epub 2010 Jul 15.

PMID:
20632211
12.

Monoclonal antibodies against toluene diisocyanate haptenated proteins from vapor-exposed mice.

Ruwona TB, Johnson VJ, Schmechel D, Simoyi RH, Beezhold D, Siegel PD.

Hybridoma (Larchmt). 2010 Jun;29(3):221-9. doi: 10.1089/hyb.2009.0110.

13.

Murine models of airway fungal exposure and allergic sensitization.

Templeton SP, Buskirk AD, Green BJ, Beezhold DH, Schmechel D.

Med Mycol. 2010 Mar;48(2):217-28. doi: 10.3109/13693780903420658. Review.

PMID:
20055736
14.

Linkage and association study of late-onset Alzheimer disease families linked to 9p21.3.

Züchner S, Gilbert JR, Martin ER, Leon-Guerrero CR, Xu PT, Browning C, Bronson PG, Whitehead P, Schmechel DE, Haines JL, Pericak-Vance MA.

Ann Hum Genet. 2008 Nov;72(Pt 6):725-31. doi: 10.1111/j.1469-1809.2008.00474.x. Epub 2008 Aug 28.

15.

Human apolipoprotein E4 targeted replacement mice show increased prevalence of intracerebral hemorrhage associated with vascular amyloid deposition.

Sullivan PM, Mace BE, Estrada JC, Schmechel DE, Alberts MJ.

J Stroke Cerebrovasc Dis. 2008 Sep;17(5):303-11. doi: 10.1016/j.jstrokecerebrovasdis.2008.03.011.

PMID:
18755411
16.

Discrimination of Penicillium isolates by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry fingerprinting.

Hettick JM, Green BJ, Buskirk AD, Kashon ML, Slaven JE, Janotka E, Blachere FM, Schmechel D, Beezhold DH.

Rapid Commun Mass Spectrom. 2008 Aug;22(16):2555-60. doi: 10.1002/rcm.3649.

PMID:
18646251
17.

Discrimination of Aspergillus isolates at the species and strain level by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry fingerprinting.

Hettick JM, Green BJ, Buskirk AD, Kashon ML, Slaven JE, Janotka E, Blachere FM, Schmechel D, Beezhold DH.

Anal Biochem. 2008 Sep 15;380(2):276-81. doi: 10.1016/j.ab.2008.05.051. Epub 2008 Jun 5.

PMID:
18577370
18.

Neuronal gene expression in non-demented individuals with intermediate Alzheimer's Disease neuropathology.

Liang WS, Dunckley T, Beach TG, Grover A, Mastroeni D, Ramsey K, Caselli RJ, Kukull WA, McKeel D, Morris JC, Hulette CM, Schmechel D, Reiman EM, Rogers J, Stephan DA.

Neurobiol Aging. 2010 Apr;31(4):549-66. doi: 10.1016/j.neurobiolaging.2008.05.013. Epub 2008 Jun 24.

19.

Neuroanatomical correlates of malingered memory impairment: event-related fMRI of deception on a recognition memory task.

Browndyke JN, Paskavitz J, Sweet LH, Cohen RA, Tucker KA, Welsh-Bohmer KA, Burke JR, Schmechel DE.

Brain Inj. 2008 Jun;22(6):481-9. doi: 10.1080/02699050802084894.

20.

Longitudinal follow-up of late-onset Alzheimer disease families.

Carney RM, Slifer MA, Lin PI, Gaskell PC, Scott WK, Potocky CF, Hulette CM, Welsh-Bohmer KA, Schmechel DE, Vance JM, Pericak-Vance MA.

Am J Med Genet B Neuropsychiatr Genet. 2008 Jul 5;147B(5):571-8. doi: 10.1002/ajmg.b.30590.

21.

Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons.

Liang WS, Reiman EM, Valla J, Dunckley T, Beach TG, Grover A, Niedzielko TL, Schneider LE, Mastroeni D, Caselli R, Kukull W, Morris JC, Hulette CM, Schmechel D, Rogers J, Stephan DA.

Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4441-6. doi: 10.1073/pnas.0709259105. Epub 2008 Mar 10.

22.

Prevalence of allergic sensitization to indoor fungi in West Virginia.

Beezhold DH, Green BJ, Blachere FM, Schmechel D, Weissman DN, Velickoff D, Hogan MB, Wilson NW.

Allergy Asthma Proc. 2008 Jan-Feb;29(1):29-34. doi: 10.2500/aap2008.29.3076.

PMID:
18302835
23.

Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set.

Liang WS, Dunckley T, Beach TG, Grover A, Mastroeni D, Ramsey K, Caselli RJ, Kukull WA, McKeel D, Morris JC, Hulette CM, Schmechel D, Reiman EM, Rogers J, Stephan DA.

Physiol Genomics. 2008 Apr 22;33(2):240-56. doi: 10.1152/physiolgenomics.00242.2007. Epub 2008 Feb 12.

24.

Neuropsychological assessment, neuroimaging, and neuropsychiatric evaluation in pediatric and adult patients with sickle cell disease (SCD).

Edwards CL, Raynor RD, Feliu M, McDougald C, Johnson S, Schmechel D, Wood M, Bennett GG, Saurona P, Bonner M, Wellington C, DeCastro LM, Whitworth E, Abrams M, Logue P, Edwards L, Martinez S, Whitfield KE.

Neuropsychiatr Dis Treat. 2007 Dec;3(6):705-9.

25.

Analytical bias of cross-reactive polyclonal antibodies for environmental immunoassays of Alternaria alternata.

Schmechel D, Green BJ, Blachere FM, Janotka E, Beezhold DH.

J Allergy Clin Immunol. 2008 Mar;121(3):763-8. Epub 2007 Nov 26.

PMID:
18036643
26.

A SAGE study of apolipoprotein E3/3, E3/4 and E4/4 allele-specific gene expression in hippocampus in Alzheimer disease.

Xu PT, Li YJ, Qin XJ, Kroner C, Green-Odlum A, Xu H, Wang TY, Schmechel DE, Hulette CM, Ervin J, Hauser M, Haines J, Pericak-Vance MA, Gilbert JR.

Mol Cell Neurosci. 2007 Nov;36(3):313-31. Epub 2007 Jul 24.

27.

No association between SNP rs498055 on chromosome 10 and late-onset Alzheimer disease in multiple datasets.

Liang X, Schnetz-Boutaud N, Bartlett J, Allen MJ, Gwirtsman H, Schmechel DE, Carney RM, Gilbert JR, Pericak-Vance MA, Haines JL.

Ann Hum Genet. 2008 Jan;72(Pt 1):141-4. Epub 2007 Aug 24.

28.

Art, alpha-1-antitrypsin polymorphisms and intense creative energy: blessing or curse?

Schmechel DE.

Neurotoxicology. 2007 Sep;28(5):899-914. Epub 2007 Jun 14.

PMID:
17659342
29.

Effect of heterogeneity on the chromosome 10 risk in late-onset Alzheimer disease.

Liang X, Martin ER, Schnetz-Boutaud N, Bartlett J, Anderson B, Züchner S, Gwirtsman H, Schmechel D, Carney R, Gilbert JR, Pericak-Vance MA, Haines JL.

Hum Mutat. 2007 Nov;28(11):1065-73.

PMID:
17573676
30.

Proxies and consent discussions for dementia research.

Sugarman J, Roter D, Cain C, Wallace R, Schmechel D, Welsh-Bohmer KA.

J Am Geriatr Soc. 2007 Apr;55(4):556-61.

PMID:
17397434
31.

Initial observations of key features of age-related macular degeneration in APOE targeted replacement mice.

Malek G, Mace B, Saloupis P, Schmechel D, Rickman D, Sullivan P, Rickman CB.

Adv Exp Med Biol. 2006;572:109-17. No abstract available.

PMID:
17249563
32.

Association analysis of genetic polymorphisms in the CDC2 gene with late-onset Alzheimer disease.

Liang X, Schnetz-Boutaud N, Bartlett J, Anderson BM, Gwirtsman H, Schmechel D, Carney R, Gilbert JR, Pericak-Vance MA, Haines JL.

Dement Geriatr Cogn Disord. 2007;23(2):126-32. Epub 2006 Dec 8.

33.

A comparative analysis of the information content in long and short SAGE libraries.

Li YJ, Xu P, Qin X, Schmechel DE, Hulette CM, Haines JL, Pericak-Vance MA, Gilbert JR.

BMC Bioinformatics. 2006 Nov 16;7:504.

34.

Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain.

Liang WS, Dunckley T, Beach TG, Grover A, Mastroeni D, Walker DG, Caselli RJ, Kukull WA, McKeel D, Morris JC, Hulette C, Schmechel D, Alexander GE, Reiman EM, Rogers J, Stephan DA.

Physiol Genomics. 2007 Feb 12;28(3):311-22. Epub 2006 Oct 31.

35.

A two-stage cyclone using microcentrifuge tubes for personal bioaerosol sampling.

Lindsley WG, Schmechel D, Chen BT.

J Environ Monit. 2006 Nov;8(11):1136-42. Epub 2006 Sep 8.

PMID:
17075620
36.

Airborne fungal fragments and allergenicity.

Green BJ, Tovey ER, Sercombe JK, Blachere FM, Beezhold DH, Schmechel D.

Med Mycol. 2006 Sep;44 Suppl 1:S245-55. Review.

PMID:
17050446
37.

Strategies for dissecting genetic-environmental interactions in neurodegenerative disorders.

Schmechel DE, Browndyke J, Ghio A.

Neurotoxicology. 2006 Sep;27(5):637-57. Epub 2006 Jun 3.

PMID:
16870258
38.

Exploring the association of glyceraldehyde-3-phosphate dehydrogenase gene and Alzheimer disease.

Lin PI, Martin ER, Bronson PG, Browning-Large C, Small GW, Schmechel DE, Welsh-Bohmer KA, Haines JL, Gilbert JR, Pericak-Vance MA.

Neurology. 2006 Jul 11;67(1):64-8.

PMID:
16832079
39.

Parsing the genetic heterogeneity of chromosome 12q susceptibility genes for Alzheimer disease by family-based association analysis.

Lin PI, Martin ER, Browning-Large CA, Schmechel DE, Welsh-Bohmer KA, Doraiswamy PM, Gilbert JR, Haines JL, Pericak-Vance MA.

Neurogenetics. 2006 Jul;7(3):157-65. Epub 2006 Jun 13.

PMID:
16770605
40.

Dual fluorescent halogen immunoassay for bioaerosols using confocal microscopy.

Green BJ, Millecchia LL, Blachere FM, Tovey ER, Beezhold DH, Schmechel D.

Anal Biochem. 2006 Jul 1;354(1):151-3. Epub 2006 Apr 18. No abstract available.

PMID:
16712767
41.

The development of species-specific immunodiagnostics for Stachybotrys chartarum: the role of cross-reactivity.

Schmechel D, Simpson JP, Beezhold D, Lewis DM.

J Immunol Methods. 2006 Feb 20;309(1-2):150-9. Epub 2006 Jan 3.

PMID:
16436280
42.

Characterization of nigerlysin, hemolysin produced by Aspergillus niger, and effect on mouse neuronal cells in vitro.

Donohue M, Wei W, Wu J, Zawia NH, Hud N, De Jesus V, Schmechel D, Hettick JM, Beezhold DH, Vesper S.

Toxicology. 2006 Feb 15;219(1-3):150-5. Epub 2005 Dec 9.

PMID:
16338047
43.

Enumeration and detection of aerosolized Aspergillus fumigatus and Penicillium chrysogenum conidia and hyphae using a novel double immunostaining technique.

Green BJ, Schmechel D, Sercombe JK, Tovey ER.

J Immunol Methods. 2005 Dec 20;307(1-2):127-34. Epub 2005 Oct 25.

PMID:
16280129
44.

Gene expression correlates of neurofibrillary tangles in Alzheimer's disease.

Dunckley T, Beach TG, Ramsey KE, Grover A, Mastroeni D, Walker DG, LaFleur BJ, Coon KD, Brown KM, Caselli R, Kukull W, Higdon R, McKeel D, Morris JC, Hulette C, Schmechel D, Reiman EM, Rogers J, Stephan DA.

Neurobiol Aging. 2006 Oct;27(10):1359-71. Epub 2005 Oct 19.

45.

Interaction between the alpha-T catenin gene (VR22) and APOE in Alzheimer's disease.

Martin ER, Bronson PG, Li YJ, Wall N, Chung RH, Schmechel DE, Small G, Xu PT, Bartlett J, Schnetz-Boutaud N, Haines JL, Gilbert JR, Pericak-Vance MA.

J Med Genet. 2005 Oct;42(10):787-92.

46.

Differences in apolipoprotein E3/3 and E4/4 allele-specific gene expression in hippocampus in Alzheimer disease.

Xu PT, Li YJ, Qin XJ, Scherzer CR, Xu H, Schmechel DE, Hulette CM, Ervin J, Gullans SR, Haines J, Pericak-Vance MA, Gilbert JR.

Neurobiol Dis. 2006 Feb;21(2):256-75. Epub 2005 Sep 29.

PMID:
16198584
47.
48.

Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration.

Malek G, Johnson LV, Mace BE, Saloupis P, Schmechel DE, Rickman DW, Toth CA, Sullivan PM, Bowes Rickman C.

Proc Natl Acad Sci U S A. 2005 Aug 16;102(33):11900-5. Epub 2005 Aug 3.

49.

Cardiovascular damage in Alzheimer disease: autopsy findings from the Bryan ADRC.

Corder EH, Ervin JF, Lockhart E, Szymanski MH, Schmechel DE, Hulette CM.

J Biomed Biotechnol. 2005 Jun 30;2005(2):189-97.

50.

Genomic convergence to identify candidate genes for Parkinson disease: SAGE analysis of the substantia nigra.

Noureddine MA, Li YJ, van der Walt JM, Walters R, Jewett RM, Xu H, Wang T, Walter JW, Scott BL, Hulette C, Schmechel D, Stenger JE, Dietrich F, Vance JM, Hauser MA.

Mov Disord. 2005 Oct;20(10):1299-309.

PMID:
15966006

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