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Elevated neutrophil-lymphocyte ratio predicts mortality following elective endovascular aneurysm repair.

King AH, Schmaier AH, Harth KC, Kumins NH, Wong VL, Zidar DA, Kashyap VS, Cho JS.

J Vasc Surg. 2020 Feb 6. pii: S0741-5214(19)32550-9. doi: 10.1016/j.jvs.2019.10.058. [Epub ahead of print]


Transferrin: a blood coagulation modifier.

Schmaier AH.

Cell Res. 2020 Feb;30(2):101-102. doi: 10.1038/s41422-020-0275-z. No abstract available.


Editorial: Proceedings of KININ2018CLE, Cleveland, Ohio, June 18-20, 2018: A Compendium of the Presentations.

Schmaier AH, Nieman MT, McCrae KR, Karnik S, Pesquero JB.

Front Med (Lausanne). 2019 Nov 22;6:272. doi: 10.3389/fmed.2019.00272. eCollection 2019. No abstract available.


Serpin targets in hemostasis/kinin formation.

Schmaier AH.

Blood. 2019 Nov 7;134(19):1566-1568. doi: 10.1182/blood.2019002713. No abstract available.


Factor XII - What's important but not commonly thought about.

Schmaier AH, Stavrou EX.

Res Pract Thromb Haemost. 2019 Jun 19;3(4):599-606. doi: 10.1002/rth2.12235. eCollection 2019 Oct. Review.


Nomenclature of factor XI and the contact system.

Schmaier AH, Emsley J, Feener EP, Gailani D, Govers-Riemslag JWP, Kaplan AP, Maas C, Morrissey JH, Renné T, Sidelmann JJ, Meijers JCM.

J Thromb Haemost. 2019 Dec;17(12):2216-2219. doi: 10.1111/jth.14595. Epub 2019 Aug 13. No abstract available.


Ponatinib treatment promotes arterial thrombosis and hyperactive platelets.

Merkulova A, Mitchell SC, Stavrou EX, Forbes GL, Schmaier AH.

Blood Adv. 2019 Aug 13;3(15):2312-2316. doi: 10.1182/bloodadvances.2019000034. No abstract available.


Acquired Hemophilia A After Nivolumab Therapy in a Patient With Metastatic Squamous Cell Carcinoma of the Lung Successfully Managed With Rituximab.

Gokozan HN, Friedman JD, Schmaier AH, Downes KA, Farah LA, Reeves HM.

Clin Lung Cancer. 2019 Sep;20(5):e560-e563. doi: 10.1016/j.cllc.2019.06.022. Epub 2019 Jun 26. No abstract available.


Venous Thromboembolism Chemoprophylaxis in Total Hip and Knee Arthroplasty: A Critical Analysis Review.

Trivedi NN, Fitzgerald SJ, Schmaier AH, Wera GD.

JBJS Rev. 2019 Jan;7(1):e2. doi: 10.2106/JBJS.RVW.18.00010. No abstract available.


The hereditary angioedema syndromes.

Schmaier AH.

J Clin Invest. 2019 Jan 2;129(1):66-68. doi: 10.1172/JCI125378. Epub 2018 Dec 10.


Factor XII Activation Promotes Platelet Consumption in the Presence of Bacterial-Type Long-Chain Polyphosphate In Vitro and In Vivo.

Zilberman-Rudenko J, Reitsma SE, Puy C, Rigg RA, Smith SA, Tucker EI, Silasi R, Merkulova A, McCrae KR, Maas C, Urbanus RT, Gailani D, Morrissey JH, Gruber A, Lupu F, Schmaier AH, McCarty OJT.

Arterioscler Thromb Vasc Biol. 2018 Aug;38(8):1748-1760. doi: 10.1161/ATVBAHA.118.311193.


Assessment of whole blood coagulation with a microfluidic dielectric sensor.

Maji D, De La Fuente M, Kucukal E, Sekhon UDS, Schmaier AH, Sen Gupta A, Gurkan UA, Nieman MT, Stavrou EX, Mohseni P, Suster MA.

J Thromb Haemost. 2018 Oct;16(10):2050-2056. doi: 10.1111/jth.14244. Epub 2018 Sep 25.


Plasma kallikrein activates the epithelial sodium channel in vitro but is not essential for volume retention in nephrotic mice.

Haerteis S, Schork A, Dörffel T, Bohnert BN, Nacken R, Wörn M, Xiao M, Essigke D, Janessa A, Schmaier AH, Feener EP, Häring HU, Bertog M, Korbmacher C, Artunc F.

Acta Physiol (Oxf). 2018 Sep;224(1):e13060. doi: 10.1111/apha.13060. Epub 2018 Mar 25.


Plasma Prekallikrein: Its Role in Hereditary Angioedema and Health and Disease.

Schmaier AH.

Front Med (Lausanne). 2018 Jan 25;5:3. doi: 10.3389/fmed.2018.00003. eCollection 2018. Review.


Factor XII and uPAR upregulate neutrophil functions to influence wound healing.

Stavrou EX, Fang C, Bane KL, Long AT, Naudin C, Kucukal E, Gandhi A, Brett-Morris A, Mumaw MM, Izadmehr S, Merkulova A, Reynolds CC, Alhalabi O, Nayak L, Yu WM, Qu CK, Meyerson HJ, Dubyak GR, Gurkan UA, Nieman MT, Sen Gupta A, Renné T, Schmaier AH.

J Clin Invest. 2018 Mar 1;128(3):944-959. doi: 10.1172/JCI92880. Epub 2018 Jan 29.


Editorial: Introduction to the Presentations at the Factor XI and the Contact System SSC Session of the ISTH, Montpellier, France, May 27, 2016.

Schmaier AH, Meijers JCM.

Front Med (Lausanne). 2017 Aug 24;4:140. doi: 10.3389/fmed.2017.00140. eCollection 2017. No abstract available.


Introduction to current issue.

Schmaier AH.

Curr Opin Hematol. 2017 Sep;24(5):409-410. doi: 10.1097/MOH.0000000000000370. No abstract available.


The amyloid beta-precursor protein-The unappreciated cerebral anticoagulant.

Schmaier AH.

Thromb Res. 2017 Jul;155:149-151. doi: 10.1016/j.thromres.2017.05.037. Epub 2017 Jun 2. No abstract available.


Contact ignition by single-chain XIIa.

Meijers JC, Schmaier AH.

Blood. 2017 Mar 16;129(11):1411-1412. doi: 10.1182/blood-2017-02-763532. No abstract available.


Prolylcarboxypeptidase deficiency is associated with increased blood pressure, glomerular lesions, and cardiac dysfunction independent of altered circulating and cardiac angiotensin II.

Maier C, Schadock I, Haber PK, Wysocki J, Ye M, Kanwar Y, Flask CA, Yu X, Hoit BD, Adams GN, Schmaier AH, Bader M, Batlle D.

J Mol Med (Berl). 2017 May;95(5):473-486. doi: 10.1007/s00109-017-1513-9. Epub 2017 Feb 3.


Plasma kallikrein enhances platelet aggregation response by subthreshold doses of ADP.

Ottaiano TF, Andrade SS, de Oliveira C, Silva MCC, Buri MV, Juliano MA, Girão MJBC, Sampaio MU, Schmaier AH, Wlodawer A, Maffei FHA, Oliva MLV.

Biochimie. 2017 Apr;135:72-81. doi: 10.1016/j.biochi.2017.01.010. Epub 2017 Jan 20.


PolyP's many faces.

Schmaier AH.

Blood. 2016 Sep 29;128(13):1669-70. doi: 10.1182/blood-2016-07-724971. No abstract available.


Antithrombotic potential of the contact activation pathway.

Schmaier AH.

Curr Opin Hematol. 2016 Sep;23(5):445-52. doi: 10.1097/MOH.0000000000000271. Review.


A Cross-sectional Study of KLKB1 and PRCP Polymorphisms in Patient Samples with Cardiovascular Disease.

Gittleman HR, Merkulova A, Alhalabi O, Stavrou EX, Veigl ML, Barnholtz-Sloan JS, Schmaier AH.

Front Med (Lausanne). 2016 Apr 29;3:17. doi: 10.3389/fmed.2016.00017. eCollection 2016.


Alzheimer disease is in part a thrombohemorrhagic disorder.

Schmaier AH.

J Thromb Haemost. 2016 May;14(5):991-4. doi: 10.1111/jth.13277. Epub 2016 Mar 16. No abstract available.


Plasma Prekallikrein Is Associated With Carotid Intima-Media Thickness in Type 1 Diabetes.

Jaffa MA, Luttrell D, Schmaier AH, Klein RL, Lopes-Virella M, Luttrell LM, Jaffa AA; DCCT/EDIC Research Group.

Diabetes. 2016 Feb;65(2):498-502. doi: 10.2337/db15-0930. Epub 2015 Nov 24.


The contact activation and kallikrein/kinin systems: pathophysiologic and physiologic activities.

Schmaier AH.

J Thromb Haemost. 2016 Jan;14(1):28-39. doi: 10.1111/jth.13194. Epub 2016 Jan 11. Review.


Medically-induced hemophilia C to treat thrombosis.

Schmaier AH.

Thromb Res. 2015 Aug;136(2):185-6. doi: 10.1016/j.thromres.2015.05.013. Epub 2015 May 22. No abstract available.


Thrombosis Prevention without Anticoagulation.

Schmaier AH.

Front Med (Lausanne). 2014 May 9;1:12. doi: 10.3389/fmed.2014.00012. eCollection 2014. No abstract available.


Reduced thrombosis in Klkb1-/- mice is mediated by increased Mas receptor, prostacyclin, Sirt1, and KLF4 and decreased tissue factor.

Stavrou EX, Fang C, Merkulova A, Alhalabi O, Grobe N, Antoniak S, Mackman N, Schmaier AH.

Blood. 2015 Jan 22;125(4):710-9. doi: 10.1182/blood-2014-01-550285. Epub 2014 Oct 22.


Prolylcarboxypeptidase independently activates plasma prekallikrein (fletcher factor).

Wang J, Matafonov A, Madkhali H, Mahdi F, Watson D, Schmaier AH, Gailani D, Shariat-Madar Z.

Curr Mol Med. 2014;14(9):1173-85.


Transmission of lupus anticoagulant by allogeneic stem cell transplantation.

Massoud MR, William BM, Harrill K, Cooper BW, de Lima M, Schmaier AH.

Rev Bras Hematol Hemoter. 2014 Jul-Aug;36(4):287-9. doi: 10.1016/j.bjhh.2014.05.008. Epub 2014 May 29.


The thromboprotective effect of bortezomib is dependent on the transcription factor Kruppel-like factor 2 (KLF2).

Nayak L, Shi H, Atkins GB, Lin Z, Schmaier AH, Jain MK.

Blood. 2014 Jun 12;123(24):3828-31. doi: 10.1182/blood-2014-01-547448. Epub 2014 Apr 25.


Physiologic activities of the contact activation system.

Schmaier AH.

Thromb Res. 2014 May;133 Suppl 1:S41-4. doi: 10.1016/j.thromres.2014.03.018.


Platelet-derived S100 family member myeloid-related protein-14 regulates thrombosis.

Wang Y, Fang C, Gao H, Bilodeau ML, Zhang Z, Croce K, Liu S, Morooka T, Sakuma M, Nakajima K, Yoneda S, Shi C, Zidar D, Andre P, Stephens G, Silverstein RL, Hogg N, Schmaier AH, Simon DI.

J Clin Invest. 2014 May;124(5):2160-71. Epub 2014 Apr 1.


Extracorporeal circulation without bleeding.

Schmaier AH.

Sci Transl Med. 2014 Feb 5;6(222):222fs7. doi: 10.1126/scitranslmed.3008497.


Prolylcarboxypeptidase promotes angiogenesis and vascular repair.

Adams GN, Stavrou EX, Fang C, Merkulova A, Alaiti MA, Nakajima K, Morooka T, Merkulov S, Larusch GA, Simon DI, Jain MK, Schmaier AH.

Blood. 2013 Aug 22;122(8):1522-31. doi: 10.1182/blood-2012-10-460360. Epub 2013 Jun 6.


Domain 2 of uPAR regulates single-chain urokinase-mediated angiogenesis through β1-integrin and VEGFR2.

Larusch GA, Merkulova A, Mahdi F, Shariat-Madar Z, Sitrin RG, Cines DB, Schmaier AH.

Am J Physiol Heart Circ Physiol. 2013 Aug 1;305(3):H305-20. doi: 10.1152/ajpheart.00110.2013. Epub 2013 May 24.


Recommendations for the Standardization of Light Transmission Aggregometry: A Consensus of the Working Party from the Platelet Physiology Subcommittee of SSC/ISTH.

Cattaneo M, Cerletti C, Harrison P, Hayward CP, Kenny D, Nugent D, Nurden P, Rao AK, Schmaier AH, Watson SP, Lussana F, Pugliano MT, Michelson AD.

J Thromb Haemost. 2013 Apr 10. doi: 10.1111/jth.12231. [Epub ahead of print]


Identification of prolyl carboxypeptidase as an alternative enzyme for processing of renal angiotensin II using mass spectrometry.

Grobe N, Weir NM, Leiva O, Ong FS, Bernstein KE, Schmaier AH, Morris M, Elased KM.

Am J Physiol Cell Physiol. 2013 May 15;304(10):C945-53. doi: 10.1152/ajpcell.00346.2012. Epub 2013 Feb 7.


Angiotensin 1-7 and Mas decrease thrombosis in Bdkrb2-/- mice by increasing NO and prostacyclin to reduce platelet spreading and glycoprotein VI activation.

Fang C, Stavrou E, Schmaier AA, Grobe N, Morris M, Chen A, Nieman MT, Adams GN, LaRusch G, Zhou Y, Bilodeau ML, Mahdi F, Warnock M, Schmaier AH.

Blood. 2013 Apr 11;121(15):3023-32. doi: 10.1182/blood-2012-09-459156. Epub 2013 Feb 5. Erratum in: Blood. 2014 Mar 6;123(10):1622.


A platelet acquired storage pool disorder associated with tamoxifen therapy.

Nayak L, Schmaier AH.

Case Rep Hematol. 2012;2012:948351. doi: 10.1155/2012/948351. Epub 2012 Dec 26.


In vivo roles of factor XII.

Renné T, Schmaier AH, Nickel KF, Blombäck M, Maas C.

Blood. 2012 Nov 22;120(22):4296-303. doi: 10.1182/blood-2012-07-292094. Epub 2012 Sep 19. Review.


The Williams-Beuren Syndrome-a window into genetic variants leading to the development of cardiovascular disease.

Adams GN, Schmaier AH.

PLoS Genet. 2012 Feb;8(2):e1002479. doi: 10.1371/journal.pgen.1002479. Epub 2012 Feb 2. No abstract available.


Increased platelet and microparticle activation in HIV infection: upregulation of P-selectin and tissue factor expression.

Mayne E, Funderburg NT, Sieg SF, Asaad R, Kalinowska M, Rodriguez B, Schmaier AH, Stevens W, Lederman MM.

J Acquir Immune Defic Syndr. 2012 Apr 1;59(4):340-6. doi: 10.1097/QAI.0b013e3182439355.


Are maternal antiplatelet antibodies a prothrombotic condition leading to miscarriage?

Schmaier AH.

J Clin Invest. 2011 Nov;121(11):4241-3. doi: 10.1172/JCI60749. Epub 2011 Oct 24.


Factor XII gene mutation in the Hageman family.

Xu-Cai YO, Shen J, Chen S, Zhou Y, Larusch GA, Stavrou E, Schmaier AH, Wu Q.

J Thromb Haemost. 2011 Nov;9(11):2329-31. doi: 10.1111/j.1538-7836.2011.04508.x. No abstract available. Erratum in: J Thromb Haemost. 2012 Jan;10(1):166.


Murine prolylcarboxypeptidase depletion induces vascular dysfunction with hypertension and faster arterial thrombosis.

Adams GN, LaRusch GA, Stavrou E, Zhou Y, Nieman MT, Jacobs GH, Cui Y, Lu Y, Jain MK, Mahdi F, Shariat-Madar Z, Okada Y, D'Alecy LG, Schmaier AH.

Blood. 2011 Apr 7;117(14):3929-37. doi: 10.1182/blood-2010-11-318527. Epub 2011 Feb 4.


Oscar D. Ratnoff: a man for all seasons.

Schmaier AH.

Thromb Haemost. 2010 Nov;104(5):863-6. doi: 10.1160/TH10-10-0632. Epub 2010 Oct 12. No abstract available.


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