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IFN Regulatory Factor 4 Controls Post-ischemic Inflammation and Prevents Chronic Kidney Disease.

Lorenz G, Moschovaki-Filippidou F, Würf V, Metzger P, Steiger S, Batz F, Carbajo-Lozoya J, Koziel J, Schnurr M, Cohen CD, Schmaderer C, Anders HJ, Lindenmeyer M, Lech M.

Front Immunol. 2019 Oct 1;10:2162. doi: 10.3389/fimmu.2019.02162. eCollection 2019.


Weak within-individual association of blood pressure and pulse wave velocity in hemodialysis is related to adverse outcomes.

Sarafidis PA, Loutradis C, Mayer CC, Karpetas A, Pagkopoulou E, Bikos A, Faitatzidou D, Wassertheurer S, Schmaderer C, Liakopoulos V, Papagianni A, London G.

J Hypertens. 2019 Nov;37(11):2200-2208. doi: 10.1097/HJH.0000000000002153.


Retinal endothelial function in cardiovascular risk patients: A randomized controlled exercise trial.

Streese L, Kotliar K, Deiseroth A, Infanger D, Gugleta K, Schmaderer C, Hanssen H.

Scand J Med Sci Sports. 2019 Oct 3. doi: 10.1111/sms.13560. [Epub ahead of print]


Plasma C-terminal agrin fragment and rapid kidney function decline in chronic kidney disease patients.

Lorenz G, Hettwer S, McCallum W, Angermann S, Wen M, Schmaderer C, Heemann U, Roos M, Renders L, Steubl D.

Medicine (Baltimore). 2019 May;98(19):e15597. doi: 10.1097/MD.0000000000015597.


A complex pattern of autonomic dysfunction in familial Mediterranean fever. Results from a controlled cross-sectional study.

Moog P, Valda K, Eren OE, Rauschel V, Kossegg SJ, Bachmann Q, Schmaderer C, Straube A, Schulze-Koops H, Witt M.

Clin Exp Rheumatol. 2019 Mar 18. [Epub ahead of print]


Impaired Retinal Vessel Dilation Predicts Mortality in End-Stage Renal Disease.

Günthner R, Hanssen H, Hauser C, Angermann S, Lorenz G, Kemmner S, Matschkal J, Braunisch MC, Kuechle C, Renders L, Moog P, Wassertheurer S, Baumann M, Hammes HP, Mayer CC, Haller B, Stryeck S, Madl T, Carbajo-Lozoya J, Heemann U, Kotliar K, Schmaderer C.

Circ Res. 2019 Apr 1. doi: 10.1161/CIRCRESAHA.118.314318. [Epub ahead of print]


Comparison of 24-hour and Office Pulse Wave Velocity for Prediction of Mortality in Hemodialysis Patients.

Matschkal J, Mayer CC, Sarafidis PA, Lorenz G, Braunisch MC, Guenthner R, Angermann S, Steubl D, Kemmner S, Bachmann Q, Hauser C, Nerl L, Baumann M, Mann JF, Moog P, Kuechle C, Renders L, Heemann U, Wassertheurer S, Schmaderer C.

Am J Nephrol. 2019;49(4):317-327. doi: 10.1159/000499532. Epub 2019 Mar 27.


Hemophagocytic lymphohistiocytosis secondary to pembrolizumab treatment with insufficient response to high-dose steroids.

Lorenz G, Schul L, Bachmann Q, Angermann S, Slotta-Huspenina J, Heemann U, Küchle C, Schmaderer C, Jäger M, Tauber R, Retz M, Moog P.

Rheumatology (Oxford). 2019 Jun 1;58(6):1106-1109. doi: 10.1093/rheumatology/key447. No abstract available.


Cognitive Impairment is Associated with Mortality in Hemodialysis Patients.

Angermann S, Schier J, Baumann M, Steubl D, Hauser C, Lorenz G, Günthner R, Braunisch MC, Kemmner S, Satanovskij R, Haller B, Heemann U, Lehnert T, Bieber R, Pachmann M, Braun J, Scherf J, Schätzle G, Fischereder M, Grimmer T, Schmaderer C.

J Alzheimers Dis. 2018;66(4):1529-1537. doi: 10.3233/JAD-180767.


STAT1 regulates macrophage number and phenotype and prevents renal fibrosis after ischemia-reperfusion injury.

Kemmner S, Bachmann Q, Steiger S, Lorenz G, Honarpisheh M, Foresto-Neto O, Wang S, Carbajo-Lozoya J, Alt V, Schulte C, Chmielewski S, Bluyssen HAR, Heemann U, Baumann M, Lech M, Schmaderer C.

Am J Physiol Renal Physiol. 2019 Feb 1;316(2):F277-F291. doi: 10.1152/ajprenal.00004.2018. Epub 2018 Nov 7.


Association of Ambulatory Blood Pressure with All-Cause and Cardiovascular Mortality in Hemodialysis Patients: Effects of Heart Failure and Atrial Fibrillation.

Mayer CC, Matschkal J, Sarafidis PA, Hagmair S, Lorenz G, Angermann S, Braunisch MC, Baumann M, Heemann U, Wassertheurer S, Schmaderer C.

J Am Soc Nephrol. 2018 Sep;29(9):2409-2417. doi: 10.1681/ASN.2018010086. Epub 2018 Jul 25.


Heterozygous COL4A3 Variants in Histologically Diagnosed Focal Segmental Glomerulosclerosis.

Braunisch MC, Büttner-Herold M, Günthner R, Satanovskij R, Riedhammer KM, Herr PM, Klein HG, Wahl D, Küchle C, Renders L, Heemann U, Schmaderer C, Hoefele J.

Front Pediatr. 2018 Jun 12;6:171. doi: 10.3389/fped.2018.00171. eCollection 2018.


Acetate-free, citrate-acidified bicarbonate dialysis improves serum calcification propensity-a preliminary study.

Lorenz G, Mayer CC, Bachmann Q, Stryeck S, Braunisch MC, Haller B, Carbajo-Lozoya J, Schmidt A, Witthauer S, Abuzahu J, Kemmner S, Angermann S, Koneru N, Wassertheurer S, Bieber R, Heemann U, Madl T, Pasch A, Schmaderer C.

Nephrol Dial Transplant. 2018 Nov 1;33(11):2043-2051. doi: 10.1093/ndt/gfy134.


A novel citrate-based protocol versus heparin anticoagulation for sustained low-efficiency dialysis in the ICU: safety, efficacy, and cost.

Wen M, Küchle C, Steubl D, Satanovskji R, Heemann U, Suttmann Y, Angermann S, Kemmner S, Rehbehn L, Huber M, Hauser C, Schmaderer C, Reichelt AL, Haller B, Renders L.

BMC Nephrol. 2018 Apr 3;19(1):79. doi: 10.1186/s12882-018-0879-4.


Hyperkalemia in patients treated with endoradiotherapy combined with amino acid infusion is associated with severe metabolic acidosis.

Pfob CH, Eiber M, Luppa P, Maurer F, Maurer T, Tauber R, D'Alessandria C, Feuerecker B, Scheidhauer K, Ott A, Heemann U, Schwaiger M, Schmaderer C.

EJNMMI Res. 2018 Feb 27;8(1):17. doi: 10.1186/s13550-018-0370-z.


Noninvasive quantitative assessment of microcirculatory disorders of the upper extremities with 2D fluorescence optical imaging.

Neumann J, Schmaderer C, Finsterer S, Zimmermann A, Steubl D, Helfen A, Berninger M, Lohöfer F, Rummeny EJ, Meier R, Wildgruber M.

Clin Hemorheol Microcirc. 2018;70(1):69-81. doi: 10.3233/CH-170321.


Worsening calcification propensity precedes all-cause and cardiovascular mortality in haemodialyzed patients.

Lorenz G, Steubl D, Kemmner S, Pasch A, Koch-Sembdner W, Pham D, Haller B, Bachmann Q, Mayer CC, Wassertheurer S, Angermann S, Lech M, Moog P, Bauer A, Heemann U, Schmaderer C.

Sci Rep. 2017 Oct 17;7(1):13368. doi: 10.1038/s41598-017-12859-6.


Altered neurovascular coupling as measured by optical imaging: a biomarker for Alzheimer's disease.

Kotliar K, Hauser C, Ortner M, Muggenthaler C, Diehl-Schmid J, Angermann S, Hapfelmeier A, Schmaderer C, Grimmer T.

Sci Rep. 2017 Oct 10;7(1):12906. doi: 10.1038/s41598-017-13349-5.


Cognitive impairment in hemodialysis patients: Implementation of cut-off values for the Montreal Cognitive Assessment (MoCA)-test for feasible screening.

Angermann S, Baumann M, Steubl D, Lorenz G, Hauser C, Suttmann Y, Reichelt AL, Satanovskij R, Sonntag F, Heemann U, Grimmer T, Schmaderer C.

PLoS One. 2017 Oct 10;12(10):e0184589. doi: 10.1371/journal.pone.0184589. eCollection 2017.


Mortality prediction in stable hemodialysis patients is refined by YKL-40, a 40-kDa glycoprotein associated with inflammation.

Lorenz G, Schmalenberg M, Kemmner S, Haller B, Steubl D, Pham D, Schreiegg A, Bachmann Q, Schmidt A, Haderer S, Huber M, Angermann S, Günthner R, Braunisch M, Hauser C, Reichelt AL, Matschkal J, Suttmann Y, Moog P, Stock K, Küchle C, Thürmel K, Renders L, Bauer A, Baumann M, Heemann U, Luppa PB, Schmaderer C.

Kidney Int. 2018 Jan;93(1):221-230. doi: 10.1016/j.kint.2017.07.010. Epub 2017 Sep 21.


Reduced Mortality in Maintenance Haemodialysis Patients on High versus Low Dialysate Magnesium: A Pilot Study.

Schmaderer C, Braunisch MC, Suttmann Y, Lorenz G, Pham D, Haller B, Angermann S, Matschkal J, Renders L, Baumann M, Braun JR, Heemann U, Küchle C.

Nutrients. 2017 Aug 23;9(9). pii: E926. doi: 10.3390/nu9090926.


Pulse wave velocity is associated with cognitive impairment in hemodialysis patients.

Angermann S, Baumann M, Wassertheurer S, Mayer CC, Steubl D, Hauser C, Suttmann Y, Reichelt AL, Satanovskij R, Lorenz G, Lukas M, Haller B, Heemann U, Grimmer T, Schmaderer C.

Clin Sci (Lond). 2017 Jun 28;131(13):1483-1493. doi: 10.1042/CS20170087. Print 2017 Jul 1.


The Babylonian confusion in describing chronic changes in renal allografts.

Kemmner S, Büttner-Herold M, Heemann U, Amann K, Schmaderer C.

Minerva Urol Nefrol. 2017 Dec;69(6):626-627. doi: 10.23736/S0393-2249.17.02883-1. Epub 2017 May 8. No abstract available.


Arteriovenous Fistula Steal Syndrome Causes Severe Tophaceous Gout.

Neumann J, Kisban S, Kemmner S, Heemann U, Moog P, Schmaderer C.

Arthritis Rheumatol. 2017 Sep;69(9):1916. doi: 10.1002/art.40131. Epub 2017 Jul 21. No abstract available.


Dietary nitrate load lowers blood pressure and renal resistive index in patients with chronic kidney disease: A pilot study.

Kemmner S, Lorenz G, Wobst J, Kessler T, Wen M, Günthner R, Stock K, Heemann U, Burkhardt K, Baumann M, Schmaderer C.

Nitric Oxide. 2017 Apr 1;64:7-15. doi: 10.1016/j.niox.2017.01.011. Epub 2017 Jan 28.


Implementation and verification of an enhanced algorithm for the automatic computation of RR-interval series derived from 24 h 12-lead ECGs.

Hagmair S, Braunisch MC, Bachler M, Schmaderer C, Hasenau AL, Bauer A, Rizas KD, Wassertheurer S, Mayer CC.

Physiol Meas. 2017 Jan;38(1):1-14. doi: 10.1088/1361-6579/38/1/1. Epub 2016 Dec 12.


Serum uromodulin predicts graft failure in renal transplant recipients.

Steubl D, Block M, Herbst V, Schlumberger W, Nockher A, Angermann S, Schmaderer C, Heemann U, Renders L, Scherberich J.

Biomarkers. 2017 Mar;22(2):171-177. doi: 10.1080/1354750X.2016.1252957. Epub 2016 Nov 14.


Rationale and study design of the prospective, longitudinal, observational cohort study "rISk strAtification in end-stage renal disease" (ISAR) study.

Schmaderer C, Tholen S, Hasenau AL, Hauser C, Suttmann Y, Wassertheurer S, Mayer CC, Bauer A, Rizas KD, Kemmner S, Kotliar K, Haller B, Mann J, Renders L, Heemann U, Baumann M.

BMC Nephrol. 2016 Oct 26;17(1):161.


Retrospective Analysis of Ultrasound-Detected Bleeding Complications after Ultrasound-Guided Transcutaneous Kidney Biopsies.

Preuss S, Kuechle C, Wagenpfeil S, Schmaderer C, Renders L, Heemann U, Stock K.

Ultrasound Med Biol. 2017 Jan;43(1):153-162. doi: 10.1016/j.ultrasmedbio.2016.09.012. Epub 2016 Oct 13.


A new missense mutation in UMOD gene leads to severely reduced serum uromodulin concentrations - A tool for the diagnosis of uromodulin-associated kidney disease.

Satanovskij R, Bader A, Block M, Herbst V, Schlumberger W, Haack T, Nockher WA, Heemann U, Renders L, Schmaderer C, Angermann S, Wen M, Meitinger T, Scherberich J, Steubl D.

Clin Biochem. 2017 Feb;50(3):155-158. doi: 10.1016/j.clinbiochem.2016.10.003. Epub 2016 Oct 10.


Comparison of Peritoneal Low-Molecular-Weight-Protein-Removal in CCPD and CAPD Patients Based on C-Terminal Agrin Fragment Clearance.

Steubl D, Roos M, Hettwer S, Angermann S, Wen M, Schmaderer C, Luppa P, Heemann U, Renders L.

Kidney Blood Press Res. 2016;41(2):175-85. doi: 10.1159/000443419. Epub 2016 Mar 10.


Plasma total C-terminal agrin fragment (tCAF) as a marker for kidney function in patients with chronic kidney disease.

Steubl D, Roos M, Hettwer S, Satanovskij R, Tholen S, Wen M, Schmaderer C, Hasenau AL, Luppa P, Stecher L, Heemann U, Renders L.

Clin Chem Lab Med. 2016 Sep 1;54(9):1487-95. doi: 10.1515/cclm-2015-1027.


Reduction of Amyloid-β Plasma Levels by Hemodialysis: An Anti-Amyloid Treatment Strategy?

Tholen S, Schmaderer C, Chmielewski S, Förstl H, Heemann U, Baumann M, Steubl D, Grimmer T.

J Alzheimers Dis. 2016;50(3):791-6. doi: 10.3233/JAD-150662.


EMMPRIN expression is involved in the development of interstitial fibrosis and tubular atrophy in human kidney allografts.

Kemmner S, Schulte C, von Weyhern CH, Schmidt R, Baumann M, Heemann U, Renders L, Schmaderer C.

Clin Transplant. 2016 Mar;30(3):218-25. doi: 10.1111/ctr.12677. Epub 2016 Jan 30.


Obesity-associated hypertension is ameliorated in patients with TLR4 single nucleotide polymorphism (SNP) rs4986790.

Schneider S, Hoppmann P, Koch W, Kemmner S, Schmaderer C, Renders L, Kastrati A, Laugwitz KL, Heemann U, Baumann M.

J Inflamm (Lond). 2015 Oct 1;12:57. doi: 10.1186/s12950-015-0100-5. eCollection 2015.


Blocking innate immunity to slow the progression of chronic kidney disease.

Schmaderer C, Heemann U.

Naunyn Schmiedebergs Arch Pharmacol. 2014 Oct;387(10):905-7. doi: 10.1007/s00210-014-1031-z. Epub 2014 Aug 10. No abstract available.


Influence of high-flux hemodialysis and hemodiafiltration on serum C-terminal agrin fragment levels in end-stage renal disease patients.

Steubl D, Hettwer S, Dahinden P, Wolf P, Luppa P, Wagner CA, Küchle C, Schmaderer C, Renders L, Heemann U, Roos M.

Transl Res. 2014 Nov;164(5):392-9. doi: 10.1016/j.trsl.2014.05.005. Epub 2014 May 16.


Serum myeloid-related protein 8/14 complex is associated with microalbuminuria in patients with type 2 diabetes.

Schmaderer C, Kemmner S, Burkhardt K, Heemann U, Baumann M.

Ther Adv Cardiovasc Dis. 2014 Jun 1;8(3):80-88. Epub 2014 Mar 24.


Plasmapheresis combined with rituximab for refractory idiopathic membranous nephropathy.

Wen M, Küchle C, Sarkar O, Renders L, Heemann U, Schmaderer C.

Int Urol Nephrol. 2014 Apr;46(4):847-8. doi: 10.1007/s11255-014-0673-6. Epub 2014 Mar 1. No abstract available.


Variability of cognitive performance during hemodialysis: standardization of cognitive assessment.

Tholen S, Schmaderer C, Kusmenkov E, Chmielewski S, Förstl H, Kehl V, Heemann U, Baumann M, Grimmer T.

Dement Geriatr Cogn Disord. 2014;38(1-2):31-8. doi: 10.1159/000357803. Epub 2014 Feb 20.


Microvascular dysfunction in the course of metabolic syndrome induced by high-fat diet.

Aoqui C, Chmielewski S, Scherer E, Eissler R, Sollinger D, Heid I, Braren R, Schmaderer C, Megens RT, Weber C, Heemann U, Tschöp M, Baumann M.

Cardiovasc Diabetol. 2014 Feb 3;13:31. doi: 10.1186/1475-2840-13-31.


Damage-associated molecular pattern activated Toll-like receptor 4 signalling modulates blood pressure in L-NAME-induced hypertension.

Sollinger D, Eißler R, Lorenz S, Strand S, Chmielewski S, Aoqui C, Schmaderer C, Bluyssen H, Zicha J, Witzke O, Scherer E, Lutz J, Heemann U, Baumann M.

Cardiovasc Res. 2014 Mar 1;101(3):464-72. doi: 10.1093/cvr/cvt265. Epub 2013 Dec 3.


Multi-modal treatment of calciphylaxis with sodium-thiosulfate, cinacalcet and sevelamer including long-term data.

Salmhofer H, Franzen M, Hitzl W, Koller J, Kreymann B, Fend F, Hauser-Kronberger C, Heemann U, Berr F, Schmaderer C.

Kidney Blood Press Res. 2013;37(4-5):346-59. doi: 10.1159/000350162. Epub 2013 Sep 22.


Identification and characterization of a defective CYP3A4 genotype in a kidney transplant patient with severely diminished tacrolimus clearance.

Werk AN, Lefeldt S, Bruckmueller H, Hemmrich-Stanisak G, Franke A, Roos M, Küchle C, Steubl D, Schmaderer C, Bräsen JH, Heemann U, Cascorbi I, Renders L.

Clin Pharmacol Ther. 2014 Apr;95(4):416-22. doi: 10.1038/clpt.2013.210. Epub 2013 Oct 14. Erratum in: Clin Pharmacol Ther. 2014 Nov;96(5):625. Clin Pharmacol Ther. 2014 Nov;96(5):625.


Progression of aortic pulse wave velocity in patients with chronic kidney disease.

Tholen S, Klofat K, Pan CR, Schmaderer C, Lutz J, Heemann U, Baumann M.

J Clin Hypertens (Greenwich). 2013 Nov;15(11):833-8. doi: 10.1111/jch.12198. Epub 2013 Sep 16.


[Update nephrology 2013].

Schmaderer C, Heemann U, Moog P.

MMW Fortschr Med. 2013 May 16;155(9):56-9; quiz 60-1. Review. German. No abstract available.


Arterial and retinal vascular changes in hypertensive and prehypertensive adolescents.

Murgan I, Beyer S, Kotliar KE, Weber L, Bechtold-Dalla Pozza S, Dalla Pozza R, Wegner A, Sitnikova D, Stock K, Heemann U, Schmaderer C, Baumann M.

Am J Hypertens. 2013 Mar;26(3):400-8. doi: 10.1093/ajh/hps091. Epub 2013 Jan 18.


Retinal pulse wave velocity in young male normotensive and mildly hypertensive subjects.

Kotliar K, Hanssen H, Eberhardt K, Vilser W, Schmaderer C, Halle M, Heemann U, Baumann M.

Microcirculation. 2013 Jul;20(5):405-15. doi: 10.1111/micc.12036.


Mineralocorticoid receptor antagonism and aldosterone synthesis inhibition do not improve glomerulosclerosis and renal interstitial fibrosis in a model of chronic kidney allograft injury.

Lahmer T, Hermans R, Schmaderer C, Chang J, Stock K, Lutz J, Heemann U, Baumann M.

Kidney Blood Press Res. 2012;35(6):561-7. doi: 10.1159/000339649. Epub 2012 Aug 8.


Immunosuppression with 4SC-101, a novel inhibitor of dihydroorotate dehydrogenase, in a rat model of renal transplantation.

Rusai K, Schmaderer C, Baumann M, Chmielewski S, Prókai A, Kis E, Szabó AJ, Leban J, Doblhofer R, Ammendola A, Lutz J, Heemann U.

Transplantation. 2012 Jun 15;93(11):1101-7. doi: 10.1097/TP.0b013e31824fd861.


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