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Items: 33

1.

Differential chemokine receptor expression and usage by pre-cDC1 and pre-cDC2.

Cook SJ, Lee Q, Wong AC, Spann BC, Vincent JN, Wong JJ, Schlitzer A, Gorrell MD, Weninger W, Roediger B.

Immunol Cell Biol. 2018 Jun 19. doi: 10.1111/imcb.12186. [Epub ahead of print]

PMID:
29920767
2.

Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming.

Christ A, Günther P, Lauterbach MAR, Duewell P, Biswas D, Pelka K, Scholz CJ, Oosting M, Haendler K, Baßler K, Klee K, Schulte-Schrepping J, Ulas T, Moorlag SJCFM, Kumar V, Park MH, Joosten LAB, Groh LA, Riksen NP, Espevik T, Schlitzer A, Li Y, Fitzgerald ML, Netea MG, Schultze JL, Latz E.

Cell. 2018 Jan 11;172(1-2):162-175.e14. doi: 10.1016/j.cell.2017.12.013.

PMID:
29328911
3.

Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity.

Mitroulis I, Ruppova K, Wang B, Chen LS, Grzybek M, Grinenko T, Eugster A, Troullinaki M, Palladini A, Kourtzelis I, Chatzigeorgiou A, Schlitzer A, Beyer M, Joosten LAB, Isermann B, Lesche M, Petzold A, Simons K, Henry I, Dahl A, Schultze JL, Wielockx B, Zamboni N, Mirtschink P, Coskun Ü, Hajishengallis G, Netea MG, Chavakis T.

Cell. 2018 Jan 11;172(1-2):147-161.e12. doi: 10.1016/j.cell.2017.11.034.

4.

Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner.

Thion MS, Low D, Silvin A, Chen J, Grisel P, Schulte-Schrepping J, Blecher R, Ulas T, Squarzoni P, Hoeffel G, Coulpier F, Siopi E, David FS, Scholz C, Shihui F, Lum J, Amoyo AA, Larbi A, Poidinger M, Buttgereit A, Lledo PM, Greter M, Chan JKY, Amit I, Beyer M, Schultze JL, Schlitzer A, Pettersson S, Ginhoux F, Garel S.

Cell. 2018 Jan 25;172(3):500-516.e16. doi: 10.1016/j.cell.2017.11.042. Epub 2017 Dec 21.

5.

Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2.

Sander J, Schmidt SV, Cirovic B, McGovern N, Papantonopoulou O, Hardt AL, Aschenbrenner AC, Kreer C, Quast T, Xu AM, Schmidleithner LM, Theis H, Thi Huong LD, Sumatoh HRB, Lauterbach MAR, Schulte-Schrepping J, Günther P, Xue J, Baßler K, Ulas T, Klee K, Katzmarski N, Herresthal S, Krebs W, Martin B, Latz E, Händler K, Kraut M, Kolanus W, Beyer M, Falk CS, Wiegmann B, Burgdorf S, Melosh NA, Newell EW, Ginhoux F, Schlitzer A, Schultze JL.

Immunity. 2017 Dec 19;47(6):1051-1066.e12. doi: 10.1016/j.immuni.2017.11.024.

6.

The Stimulation of Macrophages with TLR Ligands Supports Increased IL-19 Expression in Inflammatory Bowel Disease Patients and in Colitis Models.

Steinert A, Linas I, Kaya B, Ibrahim M, Schlitzer A, Hruz P, Radulovic K, Terracciano L, Macpherson AJ, Niess JH.

J Immunol. 2017 Oct 1;199(7):2570-2584. doi: 10.4049/jimmunol.1700350. Epub 2017 Sep 1.

PMID:
28864472
7.

Human lymphoid organ dendritic cell identity is predominantly dictated by ontogeny, not tissue microenvironment.

Heidkamp GF, Sander J, Lehmann CHK, Heger L, Eissing N, Baranska A, Lühr JJ, Hoffmann A, Reimer KC, Lux A, Söder S, Hartmann A, Zenk J, Ulas T, McGovern N, Alexiou C, Spriewald B, Mackensen A, Schuler G, Schauf B, Forster A, Repp R, Fasching PA, Purbojo A, Cesnjevar R, Ullrich E, Ginhoux F, Schlitzer A, Nimmerjahn F, Schultze JL, Dudziak D.

Sci Immunol. 2016 Dec 16;1(6). pii: eaai7677. doi: 10.1126/sciimmunol.aai7677. Epub 2016 Dec 16.

PMID:
28783692
8.

Human fetal dendritic cells promote prenatal T-cell immune suppression through arginase-2.

McGovern N, Shin A, Low G, Low D, Duan K, Yao LJ, Msallam R, Low I, Shadan NB, Sumatoh HR, Soon E, Lum J, Mok E, Hubert S, See P, Kunxiang EH, Lee YH, Janela B, Choolani M, Mattar CNZ, Fan Y, Lim TKH, Chan DKH, Tan KK, Tam JKC, Schuster C, Elbe-Bürger A, Wang XN, Bigley V, Collin M, Haniffa M, Schlitzer A, Poidinger M, Albani S, Larbi A, Newell EW, Chan JKY, Ginhoux F.

Nature. 2017 Jun 29;546(7660):662-666. doi: 10.1038/nature22795. Epub 2017 Jun 14.

PMID:
28614294
9.

Mapping the human DC lineage through the integration of high-dimensional techniques.

See P, Dutertre CA, Chen J, Günther P, McGovern N, Irac SE, Gunawan M, Beyer M, Händler K, Duan K, Sumatoh HRB, Ruffin N, Jouve M, Gea-Mallorquí E, Hennekam RCM, Lim T, Yip CC, Wen M, Malleret B, Low I, Shadan NB, Fen CFS, Tay A, Lum J, Zolezzi F, Larbi A, Poidinger M, Chan JKY, Chen Q, Rénia L, Haniffa M, Benaroch P, Schlitzer A, Schultze JL, Newell EW, Ginhoux F.

Science. 2017 Jun 9;356(6342). pii: eaag3009. doi: 10.1126/science.aag3009. Epub 2017 May 4.

PMID:
28473638
10.

Interplay between Obesity-Induced Inflammation and cGMP Signaling in White Adipose Tissue.

Sanyal A, Naumann J, Hoffmann LS, Chabowska-Kita A, Ehrlund A, Schlitzer A, Arner P, Blüher M, Pfeifer A.

Cell Rep. 2017 Jan 3;18(1):225-236. doi: 10.1016/j.celrep.2016.12.028.

11.

Tissue-resident macrophages - how to humanize our knowledge.

Schlitzer A, Schultze JL.

Immunol Cell Biol. 2017 Feb;95(2):173-177. doi: 10.1038/icb.2016.82. Epub 2016 Oct 18. Review.

PMID:
27752049
12.

Mpath maps multi-branching single-cell trajectories revealing progenitor cell progression during development.

Chen J, Schlitzer A, Chakarov S, Ginhoux F, Poidinger M.

Nat Commun. 2016 Jun 30;7:11988. doi: 10.1038/ncomms11988.

13.

Protocols for the Identification and Isolation of Antigen-Presenting Cells in Human and Mouse Tissues.

McGovern N, Schlitzer A, Janela B, Ginhoux F.

Methods Mol Biol. 2016;1423:169-80. doi: 10.1007/978-1-4939-3606-9_12.

PMID:
27142016
14.

Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors.

Paul F, Arkin Y, Giladi A, Jaitin DA, Kenigsberg E, Keren-Shaul H, Winter D, Lara-Astiaso D, Gury M, Weiner A, David E, Cohen N, Lauridsen FKB, Haas S, Schlitzer A, Mildner A, Ginhoux F, Jung S, Trumpp A, Porse BT, Tanay A, Amit I.

Cell. 2016 Jan 14;164(1-2):325. doi: 10.1016/j.cell.2015.12.046. Epub 2016 Jan 14. No abstract available.

15.

Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors.

Paul F, Arkin Y, Giladi A, Jaitin DA, Kenigsberg E, Keren-Shaul H, Winter D, Lara-Astiaso D, Gury M, Weiner A, David E, Cohen N, Lauridsen FK, Haas S, Schlitzer A, Mildner A, Ginhoux F, Jung S, Trumpp A, Porse BT, Tanay A, Amit I.

Cell. 2015 Dec 17;163(7):1663-77. doi: 10.1016/j.cell.2015.11.013. Epub 2015 Nov 25. Erratum in: Cell. 2016 Jan 14;164(1-2):325.

16.

Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota.

Vétizou M, Pitt JM, Daillère R, Lepage P, Waldschmitt N, Flament C, Rusakiewicz S, Routy B, Roberti MP, Duong CP, Poirier-Colame V, Roux A, Becharef S, Formenti S, Golden E, Cording S, Eberl G, Schlitzer A, Ginhoux F, Mani S, Yamazaki T, Jacquelot N, Enot DP, Bérard M, Nigou J, Opolon P, Eggermont A, Woerther PL, Chachaty E, Chaput N, Robert C, Mateus C, Kroemer G, Raoult D, Boneca IG, Carbonnel F, Chamaillard M, Zitvogel L.

Science. 2015 Nov 27;350(6264):1079-84. doi: 10.1126/science.aad1329. Epub 2015 Nov 5.

17.

Identification of cDC1- and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow.

Schlitzer A, Sivakamasundari V, Chen J, Sumatoh HR, Schreuder J, Lum J, Malleret B, Zhang S, Larbi A, Zolezzi F, Renia L, Poidinger M, Naik S, Newell EW, Robson P, Ginhoux F.

Nat Immunol. 2015 Jul;16(7):718-28. doi: 10.1038/ni.3200. Epub 2015 Jun 8.

PMID:
26054720
18.

Dendritic cells and monocyte-derived cells: Two complementary and integrated functional systems.

Schlitzer A, McGovern N, Ginhoux F.

Semin Cell Dev Biol. 2015 May;41:9-22. doi: 10.1016/j.semcdb.2015.03.011. Epub 2015 May 6. Review.

PMID:
25957517
19.

Population of Monocyte-Derived Macrophages.

McGovern N, Schlitzer A, Gunawan M, Jardine L, Shin A, Poyner E, Green K, Dickinson R, Wang XN, Low D, Best K, Covins S, Milne P, Pagan S, Aljefri K, Windebank M, Miranda-Saavedra D, Larbi A, Wasan PS, Kaibo D, Poidinger M, Bigley V, Ginhoux F, Collin M, Haniffa M.

Immunity. 2015 Feb 17;42(2):391. doi: 10.1016/j.immuni.2015.01.018. Epub 2015 Feb 17. No abstract available.

20.

High-dimensional analysis of the murine myeloid cell system.

Becher B, Schlitzer A, Chen J, Mair F, Sumatoh HR, Teng KW, Low D, Ruedl C, Riccardi-Castagnoli P, Poidinger M, Greter M, Ginhoux F, Newell EW.

Nat Immunol. 2014 Dec;15(12):1181-9. doi: 10.1038/ni.3006. Epub 2014 Oct 12.

PMID:
25306126
21.

Human dermal CD14⁺ cells are a transient population of monocyte-derived macrophages.

McGovern N, Schlitzer A, Gunawan M, Jardine L, Shin A, Poyner E, Green K, Dickinson R, Wang XN, Low D, Best K, Covins S, Milne P, Pagan S, Aljefri K, Windebank M, Miranda-Saavedra D, Larbi A, Wasan PS, Duan K, Poidinger M, Bigley V, Ginhoux F, Collin M, Haniffa M.

Immunity. 2014 Sep 18;41(3):465-477. doi: 10.1016/j.immuni.2014.08.006. Epub 2014 Sep 4. Erratum in: Immunity. 2015 Feb 17;42(2):391. Saavedra, Diego Miranda [corrected to Miranda-Saavedra, Diego].

22.

GM-CSF-licensed CD11b+ lung dendritic cells orchestrate Th2 immunity to Blomia tropicalis.

Zhou Q, Ho AW, Schlitzer A, Tang Y, Wong KH, Wong FH, Chua YL, Angeli V, Mortellaro A, Ginhoux F, Kemeny DM.

J Immunol. 2014 Jul 15;193(2):496-509. doi: 10.4049/jimmunol.1303138. Epub 2014 Jun 18.

23.

CD11b+ DCs rediscovered: implications for vaccination.

Ginhoux F, Schlitzer A.

Expert Rev Vaccines. 2014 Apr;13(4):445-7. doi: 10.1586/14760584.2014.893196. Epub 2014 Feb 25.

PMID:
24564769
24.

Organization of the mouse and human DC network.

Schlitzer A, Ginhoux F.

Curr Opin Immunol. 2014 Feb;26:90-9. doi: 10.1016/j.coi.2013.11.002. Epub 2013 Dec 3. Review.

PMID:
24556405
25.

The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide.

Viaud S, Saccheri F, Mignot G, Yamazaki T, Daillère R, Hannani D, Enot DP, Pfirschke C, Engblom C, Pittet MJ, Schlitzer A, Ginhoux F, Apetoh L, Chachaty E, Woerther PL, Eberl G, Bérard M, Ecobichon C, Clermont D, Bizet C, Gaboriau-Routhiau V, Cerf-Bensussan N, Opolon P, Yessaad N, Vivier E, Ryffel B, Elson CO, Doré J, Kroemer G, Lepage P, Boneca IG, Ghiringhelli F, Zitvogel L.

Science. 2013 Nov 22;342(6161):971-6. doi: 10.1126/science.1240537.

26.

Neutrophil mobilization via plerixafor-mediated CXCR4 inhibition arises from lung demargination and blockade of neutrophil homing to the bone marrow.

Devi S, Wang Y, Chew WK, Lima R, A-González N, Mattar CN, Chong SZ, Schlitzer A, Bakocevic N, Chew S, Keeble JL, Goh CC, Li JL, Evrard M, Malleret B, Larbi A, Renia L, Haniffa M, Tan SM, Chan JK, Balabanian K, Nagasawa T, Bachelerie F, Hidalgo A, Ginhoux F, Kubes P, Ng LG.

J Exp Med. 2013 Oct 21;210(11):2321-36. doi: 10.1084/jem.20130056. Epub 2013 Sep 30.

27.

Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes.

Jakubzick C, Gautier EL, Gibbings SL, Sojka DK, Schlitzer A, Johnson TE, Ivanov S, Duan Q, Bala S, Condon T, van Rooijen N, Grainger JR, Belkaid Y, Ma'ayan A, Riches DW, Yokoyama WM, Ginhoux F, Henson PM, Randolph GJ.

Immunity. 2013 Sep 19;39(3):599-610. doi: 10.1016/j.immuni.2013.08.007. Epub 2013 Sep 5.

28.

DNGR-ing the dendritic cell lineage.

Schlitzer A, Ginhoux F.

EMBO Rep. 2013 Oct;14(10):850-1. doi: 10.1038/embor.2013.129. Epub 2013 Aug 16. No abstract available.

29.

IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses.

Schlitzer A, McGovern N, Teo P, Zelante T, Atarashi K, Low D, Ho AW, See P, Shin A, Wasan PS, Hoeffel G, Malleret B, Heiseke A, Chew S, Jardine L, Purvis HA, Hilkens CM, Tam J, Poidinger M, Stanley ER, Krug AB, Renia L, Sivasankar B, Ng LG, Collin M, Ricciardi-Castagnoli P, Honda K, Haniffa M, Ginhoux F.

Immunity. 2013 May 23;38(5):970-83. doi: 10.1016/j.immuni.2013.04.011.

30.

Complement mediated signaling on pulmonary CD103(+) dendritic cells is critical for their migratory function in response to influenza infection.

Kandasamy M, Ying PC, Ho AW, Sumatoh HR, Schlitzer A, Hughes TR, Kemeny DM, Morgan BP, Ginhoux F, Sivasankar B.

PLoS Pathog. 2013 Jan;9(1):e1003115. doi: 10.1371/journal.ppat.1003115. Epub 2013 Jan 10.

31.

Tissue-specific differentiation of a circulating CCR9- pDC-like common dendritic cell precursor.

Schlitzer A, Heiseke AF, Einwächter H, Reindl W, Schiemann M, Manta CP, See P, Niess JH, Suter T, Ginhoux F, Krug AB.

Blood. 2012 Jun 21;119(25):6063-71. doi: 10.1182/blood-2012-03-418400. Epub 2012 Apr 30.

32.

Antigen delivery to plasmacytoid dendritic cells via BST2 induces protective T cell-mediated immunity.

Loschko J, Schlitzer A, Dudziak D, Drexler I, Sandholzer N, Bourquin C, Reindl W, Krug AB.

J Immunol. 2011 Jun 15;186(12):6718-25. doi: 10.4049/jimmunol.1004029. Epub 2011 May 9.

33.

Identification of CCR9- murine plasmacytoid DC precursors with plasticity to differentiate into conventional DCs.

Schlitzer A, Loschko J, Mair K, Vogelmann R, Henkel L, Einwächter H, Schiemann M, Niess JH, Reindl W, Krug A.

Blood. 2011 Jun 16;117(24):6562-70. doi: 10.1182/blood-2010-12-326678. Epub 2011 Apr 20.

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