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Items: 44

1.

Tributyltin induces a transcriptional response without a brite adipocyte signature in adipocyte models.

Kim S, Li A, Monti S, Schlezinger JJ.

Arch Toxicol. 2018 Sep;92(9):2859-2874. doi: 10.1007/s00204-018-2268-y. Epub 2018 Jul 19.

PMID:
30027469
2.

Towards Resolving the Pro- and Anti-Tumor Effects of the Aryl Hydrocarbon Receptor.

Narasimhan S, Stanford Zulick E, Novikov O, Parks AJ, Schlezinger JJ, Wang Z, Laroche F, Feng H, Mulas F, Monti S, Sherr DH.

Int J Mol Sci. 2018 May 7;19(5). pii: E1388. doi: 10.3390/ijms19051388.

3.

Tributyltin induces distinct effects on cortical and trabecular bone in female C57Bl/6J mice.

Watt J, Baker AH, Meeks B, Pajevic PD, Morgan EF, Gerstenfeld LC, Schlezinger JJ.

J Cell Physiol. 2018 Sep;233(9):7007-7021. doi: 10.1002/jcp.26495. Epub 2018 Mar 25.

PMID:
29380368
4.

From the Cover: Tributyltin Alters the Bone Marrow Microenvironment and Suppresses B Cell Development.

Baker AH, Wu TH, Bolt AM, Gerstenfeld LC, Mann KK, Schlezinger JJ.

Toxicol Sci. 2017 Jul 1;158(1):63-75. doi: 10.1093/toxsci/kfx067.

5.

Characterization of Adipogenic Chemicals in Three Different Cell Culture Systems: Implications for Reproducibility Based on Cell Source and Handling.

Kassotis CD, Masse L, Kim S, Schlezinger JJ, Webster TF, Stapleton HM.

Sci Rep. 2017 Feb 8;7:42104. doi: 10.1038/srep42104.

6.

Generalized Concentration Addition Modeling Predicts Mixture Effects of Environmental PPARγ Agonists.

Watt J, Webster TF, Schlezinger JJ.

Toxicol Sci. 2016 Sep;153(1):18-27. doi: 10.1093/toxsci/kfw100. Epub 2016 Jun 2.

7.

Tungsten Promotes Sex-Specific Adipogenesis in the Bone by Altering Differentiation of Bone Marrow-Resident Mesenchymal Stromal Cells.

Bolt AM, Grant MP, Wu TH, Flores Molina M, Plourde D, Kelly AD, Negro Silva LF, Lemaire M, Schlezinger JJ, Mwale F, Mann KK.

Toxicol Sci. 2016 Apr;150(2):333-46. doi: 10.1093/toxsci/kfw008. Epub 2016 Feb 9.

8.

Tributyltin engages multiple nuclear receptor pathways and suppresses osteogenesis in bone marrow multipotent stromal cells.

Baker AH, Watt J, Huang CK, Gerstenfeld LC, Schlezinger JJ.

Chem Res Toxicol. 2015 Jun 15;28(6):1156-66. doi: 10.1021/tx500433r. Epub 2015 May 13.

9.

Structurally-diverse, PPARγ-activating environmental toxicants induce adipogenesis and suppress osteogenesis in bone marrow mesenchymal stromal cells.

Watt J, Schlezinger JJ.

Toxicology. 2015 May 4;331:66-77. doi: 10.1016/j.tox.2015.03.006. Epub 2015 Mar 14.

10.

In silico identification of an aryl hydrocarbon receptor antagonist with biological activity in vitro and in vivo.

Parks AJ, Pollastri MP, Hahn ME, Stanford EA, Novikov O, Franks DG, Haigh SE, Narasimhan S, Ashton TD, Hopper TG, Kozakov D, Beglov D, Vajda S, Schlezinger JJ, Sherr DH.

Mol Pharmacol. 2014 Nov;86(5):593-608. doi: 10.1124/mol.114.093369. Epub 2014 Aug 26.

11.

Ligand binding and activation of PPARγ by Firemaster® 550: effects on adipogenesis and osteogenesis in vitro.

Pillai HK, Fang M, Beglov D, Kozakov D, Vajda S, Stapleton HM, Webster TF, Schlezinger JJ.

Environ Health Perspect. 2014 Nov;122(11):1225-32. doi: 10.1289/ehp.1408111. Epub 2014 Jul 25.

12.

What Are We Putting in Our Food That Is Making Us Fat? Food Additives, Contaminants, and Other Putative Contributors to Obesity.

Simmons AL, Schlezinger JJ, Corkey BE.

Curr Obes Rep. 2014 Jun 1;3(2):273-85. doi: 10.1007/s13679-014-0094-y.

13.

Intrinsic Sex-Linked Variations in Osteogenic and Adipogenic Differentiation Potential of Bone Marrow Multipotent Stromal Cells.

Bragdon B, Burns R, Baker AH, Belkina AC, Morgan EF, Denis GV, Gerstenfeld LC, Schlezinger JJ.

J Cell Physiol. 2015 Feb;230(2):296-307. doi: 10.1002/jcp.24705.

14.

Rodent thyroid, liver, and fetal testis toxicity of the monoester metabolite of bis-(2-ethylhexyl) tetrabromophthalate (tbph), a novel brominated flame retardant present in indoor dust.

Springer C, Dere E, Hall SJ, McDonnell EV, Roberts SC, Butt CM, Stapleton HM, Watkins DJ, McClean MD, Webster TF, Schlezinger JJ, Boekelheide K.

Environ Health Perspect. 2012 Dec;120(12):1711-9. doi: 10.1289/ehp.1204932. Epub 2012 Sep 26.

15.

EZR1: a novel family of highly expressed retroelements induced by TCDD and regulated by a NF-κB-like factor in embryos of zebrafish (Danio rerio).

Goldstone HM, Tokunaga S, Schlezinger JJ, Goldstone JV, Stegeman JJ.

Zebrafish. 2012 Mar;9(1):15-25. doi: 10.1089/zeb.2011.0722. Epub 2012 Feb 22.

16.

Organotins are potent activators of PPARγ and adipocyte differentiation in bone marrow multipotent mesenchymal stromal cells.

Yanik SC, Baker AH, Mann KK, Schlezinger JJ.

Toxicol Sci. 2011 Aug;122(2):476-88. doi: 10.1093/toxsci/kfr140. Epub 2011 May 27.

17.

The role of CaMKII in calcium-activated death pathways in bone marrow B cells.

Bissonnette SL, Haas A, Mann KK, Schlezinger JJ.

Toxicol Sci. 2010 Nov;118(1):108-18. doi: 10.1093/toxsci/kfq256. Epub 2010 Sep 1.

18.

Proximal events in 7,12-dimethylbenz[a]anthracene-induced, stromal cell-dependent bone marrow B cell apoptosis: stromal cell-B cell communication and apoptosis signaling.

Teague JE, Ryu HY, Kirber M, Sherr DH, Schlezinger JJ.

J Immunol. 2010 Sep 15;185(6):3369-78. doi: 10.4049/jimmunol.0902541. Epub 2010 Aug 18.

19.

Direct assessment of cumulative aryl hydrocarbon receptor agonist activity in sera from experimentally exposed mice and environmentally exposed humans.

Schlezinger JJ, Bernard PL, Haas A, Grandjean P, Weihe P, Sherr DH.

Environ Health Perspect. 2010 May;118(5):693-8. doi: 10.1289/ehp.0901113.

20.

Generalized concentration addition predicts joint effects of aryl hydrocarbon receptor agonists with partial agonists and competitive antagonists.

Howard GJ, Schlezinger JJ, Hahn ME, Webster TF.

Environ Health Perspect. 2010 May;118(5):666-72. doi: 10.1289/ehp.0901312.

21.
22.

An L-tyrosine derivative and PPARgamma agonist, GW7845, activates a multifaceted caspase cascade in bone marrow B cells.

Schlezinger JJ, Emberley JK, Bissonnette SL, Sherr DH.

Toxicol Sci. 2007 Jul;98(1):125-36. Epub 2007 Mar 30.

PMID:
17400580
23.

A role for the aryl hydrocarbon receptor in mammary gland tumorigenesis.

Schlezinger JJ, Liu D, Farago M, Seldin DC, Belguise K, Sonenshein GE, Sherr DH.

Biol Chem. 2006 Sep;387(9):1175-87. Review.

PMID:
16972784
25.

Uncoupling of cytochrome P450 1A and stimulation of reactive oxygen species production by co-planar polychlorinated biphenyl congeners.

Schlezinger JJ, Struntz WD, Goldstone JV, Stegeman JJ.

Aquat Toxicol. 2006 May 25;77(4):422-32. Epub 2006 Feb 28.

PMID:
16500718
26.

CYP1A1 in polycyclic aromatic hydrocarbon-induced B lymphocyte growth suppression.

Allan LL, Schlezinger JJ, Shansab M, Sherr DH.

Biochem Biophys Res Commun. 2006 Mar 31;342(1):227-35. Epub 2006 Feb 3.

PMID:
16472762
27.

Environmental chemical-induced bone marrow B cell apoptosis: death receptor-independent activation of a caspase-3 to caspase-8 pathway.

Ryu HY, Emberley JK, Schlezinger JJ, Allan LL, Na S, Sherr DH.

Mol Pharmacol. 2005 Oct;68(4):1087-96. Epub 2005 Jul 12.

PMID:
16014577
29.
30.

Bone marrow stromal-B cell interactions in polycyclic aromatic hydrocarbon-induced pro/pre-B cell apoptosis.

Allan LL, Mann KK, Matulka RA, Ryu HY, Schlezinger JJ, Sherr DH.

Toxicol Sci. 2003 Dec;76(2):357-65. Epub 2003 Sep 26.

PMID:
14514961
31.
32.

Bax, caspase-2, and caspase-3 are required for ovarian follicle loss caused by 4-vinylcyclohexene diepoxide exposure of female mice in vivo.

Takai Y, Canning J, Perez GI, Pru JK, Schlezinger JJ, Sherr DH, Kolesnick RN, Yuan J, Flavell RA, Korsmeyer SJ, Tilly JL.

Endocrinology. 2003 Jan;144(1):69-74.

PMID:
12488331
33.

Peroxisome proliferator-activated receptor gamma-mediated NF-kappa B activation and apoptosis in pre-B cells.

Schlezinger JJ, Jensen BA, Mann KK, Ryu HY, Sherr DH.

J Immunol. 2002 Dec 15;169(12):6831-41.

34.

3,3',4,4'-Tetrachlorobiphenyl oxidation in fish, bird and reptile species: relationship to cytochrome P450 1A inactivation and reactive oxygen production.

Schlezinger JJ, Keller J, Verbrugge LA, Stegeman JJ.

Comp Biochem Physiol C Toxicol Pharmacol. 2000 Mar;125(3):273-86.

PMID:
11790349
35.

Aromatic hydrocarbon receptor-driven Bax gene expression is required for premature ovarian failure caused by biohazardous environmental chemicals.

Matikainen T, Perez GI, Jurisicova A, Pru JK, Schlezinger JJ, Ryu HY, Laine J, Sakai T, Korsmeyer SJ, Casper RF, Sherr DH, Tilly JL.

Nat Genet. 2001 Aug;28(4):355-60.

PMID:
11455387
36.

Cytochrome P450 1A expression in midwater fishes: potential effects of chemical contaminants in remote oceanic zones.

Stegeman JJ, Schlezinger JJ, Craddock JE, Tillitt DE.

Environ Sci Technol. 2001 Jan 1;35(1):54-62.

PMID:
11352026
38.

The role of NF-kappaB as a survival factor in environmental chemical-induced pre-B cell apoptosis.

Mann KK, Doerre S, Schlezinger JJ, Sherr DH, Quadri S.

Mol Pharmacol. 2001 Feb;59(2):302-9.

PMID:
11160867
39.

In vitro metabolism of polychlorinated biphenyl congeners by beluga whale (Delphinapterus leucas) and pilot whale (Globicephala melas) and relationship to cytochrome P450 expression.

White RD, Shea D, Schlezinger JJ, Hahn ME, Stegeman JJ.

Comp Biochem Physiol C Toxicol Pharmacol. 2000 Jul;126(3):267-84.

PMID:
11048677
40.
41.

Identification of NF-kappaB in the marine fish Stenotomus chrysops and examination of its activation by aryl hydrocarbon receptor agonists.

Schlezinger JJ, Blickarz CE, Mann KK, Doerre S, Stegeman JJ.

Chem Biol Interact. 2000 May 1;126(2):137-57.

PMID:
10862814
43.
44.

Arachidonic acid metabolism in the marine fish Stenotomus chrysops (Scup) and the effects of cytochrome P450 1A inducers.

Schlezinger JJ, Parker C, Zeldin DC, Stegeman JJ.

Arch Biochem Biophys. 1998 May 15;353(2):265-75.

PMID:
9606961

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