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Items: 1 to 50 of 508

1.

Murine neuroblastoma cell lines developed by conditional reprogramming preserve heterogeneous phenotypes observed in vivo.

Krawczyk E, Hong SH, Galli S, Trinh E, Wietlisbach L, Misiukiewicz SF, Tilan JU, Chen YS, Schlegel R, Kitlinska J.

Lab Invest. 2019 Aug 13. doi: 10.1038/s41374-019-0297-7. [Epub ahead of print]

PMID:
31409888
2.

Continuous culture of urine-derived bladder cancer cells for precision medicine.

Jiang S, Wang J, Yang C, Tan R, Hou J, Shi Y, Zhang H, Ma S, Wang J, Zhang M, Philips G, Li Z, Ma J, Yu W, Wang G, Wu Y, Schlegel R, Wang H, Cao S, Guo J, Liu X, Dang Y.

Protein Cell. 2019 Jul 25. doi: 10.1007/s13238-019-0649-5. [Epub ahead of print] No abstract available.

PMID:
31347094
3.

Fidelity of a PDX-CR model for bladder cancer.

Mondal AM, Ma AH, Li G, Krawczyk E, Yuan R, Lu J, Schlegel R, Stamatakis L, Kowalczyk KJ, Philips GK, Pan CX, Liu X.

Biochem Biophys Res Commun. 2019 Sep 10;517(1):49-56. doi: 10.1016/j.bbrc.2019.06.165. Epub 2019 Jul 11.

PMID:
31303270
4.

Why do people believe in a "true self"? The role of essentialist reasoning about personal identity and the self.

Christy AG, Schlegel RJ, Cimpian A.

J Pers Soc Psychol. 2019 Aug;117(2):386-416. doi: 10.1037/pspp0000254.

PMID:
31282736
5.

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Ghandi M, Huang FW, Jané-Valbuena J, Kryukov GV, Lo CC, McDonald ER 3rd, Barretina J, Gelfand ET, Bielski CM, Li H, Hu K, Andreev-Drakhlin AY, Kim J, Hess JM, Haas BJ, Aguet F, Weir BA, Rothberg MV, Paolella BR, Lawrence MS, Akbani R, Lu Y, Tiv HL, Gokhale PC, de Weck A, Mansour AA, Oh C, Shih J, Hadi K, Rosen Y, Bistline J, Venkatesan K, Reddy A, Sonkin D, Liu M, Lehar J, Korn JM, Porter DA, Jones MD, Golji J, Caponigro G, Taylor JE, Dunning CM, Creech AL, Warren AC, McFarland JM, Zamanighomi M, Kauffmann A, Stransky N, Imielinski M, Maruvka YE, Cherniack AD, Tsherniak A, Vazquez F, Jaffe JD, Lane AA, Weinstock DM, Johannessen CM, Morrissey MP, Stegmeier F, Schlegel R, Hahn WC, Getz G, Mills GB, Boehm JS, Golub TR, Garraway LA, Sellers WR.

Nature. 2019 May;569(7757):503-508. doi: 10.1038/s41586-019-1186-3. Epub 2019 May 8.

PMID:
31068700
6.

Safety and clinical activity of PD-L1 blockade in patients with aggressive recurrent respiratory papillomatosis.

Allen CT, Lee S, Norberg SM, Kovalovsky D, Ye H, Clavijo PE, Hu-Lieskovan S, Schlegel R, Schlom J, Strauss J, Gulley JL, Trepel J, Hinrichs CS.

J Immunother Cancer. 2019 May 3;7(1):119. doi: 10.1186/s40425-019-0603-3.

7.

Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Barretina J, Caponigro G, Stransky N, Venkatesan K, Margolin AA, Kim S, Wilson CJ, Lehár J, Kryukov GV, Sonkin D, Reddy A, Liu M, Murray L, Berger MF, Monahan JE, Morais P, Meltzer J, Korejwa A, Jané-Valbuena J, Mapa FA, Thibault J, Bric-Furlong E, Raman P, Shipway A, Engels IH, Cheng J, Yu GK, Yu J, Aspesi P Jr, de Silva M, Jagtap K, Jones MD, Wang L, Hatton C, Palescandolo E, Gupta S, Mahan S, Sougnez C, Onofrio RC, Liefeld T, MacConaill L, Winckler W, Reich M, Li N, Mesirov JP, Gabriel SB, Getz G, Ardlie K, Chan V, Myer VE, Weber BL, Porter J, Warmuth M, Finan P, Harris JL, Meyerson M, Golub TR, Morrissey MP, Sellers WR, Schlegel R, Garraway LA.

Nature. 2019 Jan;565(7738):E5-E6. doi: 10.1038/s41586-018-0722-x. No abstract available.

PMID:
30559381
8.

Long-term expansion of primary equine keratinocytes that maintain the ability to differentiate into stratified epidermis.

Alkhilaiwi F, Wang L, Zhou D, Raudsepp T, Ghosh S, Paul S, Palechor-Ceron N, Brandt S, Luff J, Liu X, Schlegel R, Yuan H.

Stem Cell Res Ther. 2018 Jul 4;9(1):181. doi: 10.1186/s13287-018-0918-x.

9.

Δ133p53α, a natural p53 isoform, contributes to conditional reprogramming and long-term proliferation of primary epithelial cells.

Mondal AM, Zhou H, Horikawa I, Suprynowicz FA, Li G, Dakic A, Rosenthal B, Ye L, Harris CC, Schlegel R, Liu X.

Cell Death Dis. 2018 Jul 3;9(7):750. doi: 10.1038/s41419-018-0767-7.

10.

Moral Goodness Is the Essence of Personal Identity.

De Freitas J, Cikara M, Grossmann I, Schlegel R.

Trends Cogn Sci. 2018 Sep;22(9):739-740. doi: 10.1016/j.tics.2018.05.006. Epub 2018 Jun 25. No abstract available.

PMID:
29954709
11.

Thinking about a new decade in life increases personal self-reflection: A replication and reinterpretation of Alter and Hershfield's (2014) findings.

Kim J, Schlegel RJ, Seto E, Hicks JA.

J Pers Soc Psychol. 2019 Aug;117(2):e27-e34. doi: 10.1037/pspp0000199. Epub 2018 Jun 28.

PMID:
29952577
12.

How Do People Judge Meaning in Goal-Directed Behaviors: The Interplay Between Self-Concordance and Performance.

Zhang H, Chen K, Schlegel R.

Pers Soc Psychol Bull. 2018 Nov;44(11):1582-1600. doi: 10.1177/0146167218771330. Epub 2018 May 9.

PMID:
29742996
13.

Correction: MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells.

Wang Y, Li YM, Baitsch L, Huang A, Xiang Y, Tong H, Lako A, Von T, Choi C, Lim E, Min J, Li L, Stegmeier F, Schlegel R, Eck MJ, Gray NS, Mitchison TJ, Zhao JJ.

Elife. 2018 Mar 12;7. pii: e36414. doi: 10.7554/eLife.36414. No abstract available.

14.

Patient-derived conditionally reprogrammed cells maintain intra-tumor genetic heterogeneity.

Correa BRS, Hu J, Penalva LOF, Schlegel R, Rimm DL, Galante PAF, Agarwal S.

Sci Rep. 2018 Mar 6;8(1):4097. doi: 10.1038/s41598-018-22427-1.

15.

Direct HPV E6/Myc interactions induce histone modifications, Pol II phosphorylation, and hTERT promoter activation.

Zhang Y, Dakic A, Chen R, Dai Y, Schlegel R, Liu X.

Oncotarget. 2017 Oct 25;8(56):96323-96339. doi: 10.18632/oncotarget.22036. eCollection 2017 Nov 10.

16.

A multiplex preclinical model for adenoid cystic carcinoma of the salivary gland identifies regorafenib as a potential therapeutic drug.

Chen C, Choudhury S, Wangsa D, Lescott CJ, Wilkins DJ, Sripadhan P, Liu X, Wangsa D, Ried T, Moskaluk C, Wick MJ, Glasgow E, Schlegel R, Agarwal S.

Sci Rep. 2017 Sep 12;7(1):11410. doi: 10.1038/s41598-017-11764-2.

17.

Structural and Electronic Flexibility in Hydrides of Zintl Phases with Tetrel-Hydrogen and Tetrel-Tetrel Bonds.

Auer H, Schlegel R, Oeckler O, Kohlmann H.

Angew Chem Int Ed Engl. 2017 Sep 25;56(40):12344-12347. doi: 10.1002/anie.201706523. Epub 2017 Aug 25.

PMID:
28727236
18.

Conditional cell reprogramming involves non-canonical β-catenin activation and mTOR-mediated inactivation of Akt.

Suprynowicz FA, Kamonjoh CM, Krawczyk E, Agarwal S, Wellstein A, Agboke FA, Choudhury S, Liu X, Schlegel R.

PLoS One. 2017 Jul 10;12(7):e0180897. doi: 10.1371/journal.pone.0180897. eCollection 2017.

19.

Origins of the Belief in Good True Selves.

De Freitas J, Cikara M, Grossmann I, Schlegel R.

Trends Cogn Sci. 2017 Sep;21(9):634-636. doi: 10.1016/j.tics.2017.05.009. Epub 2017 Jun 7.

PMID:
28601535
20.

PD-L1 expression and CD8+ infiltration shows heterogeneity in juvenile recurrent respiratory papillomatosis.

Liu T, Greenberg M, Wentland C, Sepe B, Bowe S, Diercks G, Huynh T, Mino-Kenudson M, Schlegel R, Kodack D, Benes C, Engelman J, Hartnick C.

Int J Pediatr Otorhinolaryngol. 2017 Apr;95:133-138. doi: 10.1016/j.ijporl.2017.02.022. Epub 2017 Feb 21.

PMID:
28576522
21.

The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activation.

Kodack DP, Askoxylakis V, Ferraro GB, Sheng Q, Badeaux M, Goel S, Qi X, Shankaraiah R, Cao ZA, Ramjiawan RR, Bezwada D, Patel B, Song Y, Costa C, Naxerova K, Wong CSF, Kloepper J, Das R, Tam A, Tanboon J, Duda DG, Miller CR, Siegel MB, Anders CK, Sanders M, Estrada MV, Schlegel R, Arteaga CL, Brachtel E, Huang A, Fukumura D, Engelman JA, Jain RK.

Sci Transl Med. 2017 May 24;9(391). pii: eaal4682. doi: 10.1126/scitranslmed.aal4682. Erratum in: Sci Transl Med. 2019 Jan 30;11(477):.

22.

Maternal hypomagnesemia alters hippocampal NMDAR subunit expression and programs anxiety-like behaviour in adult offspring.

Schlegel RN, Spiers JG, Moritz KM, Cullen CL, Björkman ST, Paravicini TM.

Behav Brain Res. 2017 Jun 15;328:39-47. doi: 10.1016/j.bbr.2017.04.009. Epub 2017 Apr 4.

PMID:
28389335
23.

HPV positive neuroendocrine cervical cancer cells are dependent on Myc but not E6/E7 viral oncogenes.

Yuan H, Krawczyk E, Blancato J, Albanese C, Zhou D, Wang N, Paul S, Alkhilaiwi F, Palechor-Ceron N, Dakic A, Fang S, Choudhary S, Hou TW, Zheng YL, Haddad BR, Usuda Y, Hartmann D, Symer D, Gillison M, Agarwal S, Wangsa D, Ried T, Liu X, Schlegel R.

Sci Rep. 2017 Apr 5;7:45617. doi: 10.1038/srep45617.

24.

Conditional reprogramming and long-term expansion of normal and tumor cells from human biospecimens.

Liu X, Krawczyk E, Suprynowicz FA, Palechor-Ceron N, Yuan H, Dakic A, Simic V, Zheng YL, Sripadhan P, Chen C, Lu J, Hou TW, Choudhury S, Kallakury B, Tang DG, Darling T, Thangapazham R, Timofeeva O, Dritschilo A, Randell SH, Albanese C, Agarwal S, Schlegel R.

Nat Protoc. 2017 Feb;12(2):439-451. doi: 10.1038/nprot.2016.174. Epub 2017 Jan 26.

25.

Conditionally reprogrammed normal and primary tumor prostate epithelial cells: a novel patient-derived cell model for studies of human prostate cancer.

Timofeeva OA, Palechor-Ceron N, Li G, Yuan H, Krawczyk E, Zhong X, Liu G, Upadhyay G, Dakic A, Yu S, Fang S, Choudhury S, Zhang X, Ju A, Lee MS, Dan HC, Ji Y, Hou Y, Zheng YL, Albanese C, Rhim J, Schlegel R, Dritschilo A, Liu X.

Oncotarget. 2017 Apr 4;8(14):22741-22758. doi: 10.18632/oncotarget.13937.

26.

Pharmacological Rescue of Conditionally Reprogrammed Cystic Fibrosis Bronchial Epithelial Cells.

Gentzsch M, Boyles SE, Cheluvaraju C, Chaudhry IG, Quinney NL, Cho C, Dang H, Liu X, Schlegel R, Randell SH.

Am J Respir Cell Mol Biol. 2017 May;56(5):568-574. doi: 10.1165/rcmb.2016-0276MA.

27.

Genomic Sequence of Canine Papillomavirus 19.

Tisza MJ, Yuan H, Schlegel R, Buck CB.

Genome Announc. 2016 Dec 8;4(6). pii: e01380-16. doi: 10.1128/genomeA.01380-16.

28.

High-Order Drug Combinations Are Required to Effectively Kill Colorectal Cancer Cells.

Horn T, Ferretti S, Ebel N, Tam A, Ho S, Harbinski F, Farsidjani A, Zubrowski M, Sellers WR, Schlegel R, Porter D, Morris E, Wuerthner J, Jeay S, Greshock J, Halilovic E, Garraway LA, Caponigro G, Lehár J.

Cancer Res. 2016 Dec 1;76(23):6950-6963. Epub 2016 Sep 22.

29.

Straying From the Righteous Path and From Ourselves: The Interplay Between Perceptions of Morality and Self-Knowledge.

Christy AG, Seto E, Schlegel RJ, Vess M, Hicks JA.

Pers Soc Psychol Bull. 2016 Nov;42(11):1538-1550. doi: 10.1177/0146167216665095. Epub 2016 Sep 28.

PMID:
27655752
30.

True self-alienation positively predicts reports of mindwandering.

Vess M, Leal SA, Hoeldtke RT, Schlegel RJ, Hicks JA.

Conscious Cogn. 2016 Oct;45:89-99. doi: 10.1016/j.concog.2016.08.018. Epub 2016 Aug 28.

PMID:
27580460
31.

ROCK inhibitor reduces Myc-induced apoptosis and mediates immortalization of human keratinocytes.

Dakic A, DiVito K, Fang S, Suprynowicz F, Gaur A, Li X, Palechor-Ceron N, Simic V, Choudhury S, Yu S, Simbulan-Rosenthal CM, Rosenthal D, Schlegel R, Liu X.

Oncotarget. 2016 Oct 11;7(41):66740-66753. doi: 10.18632/oncotarget.11458.

32.

Two distinct superconducting phases in LiFeAs.

Nag PK, Schlegel R, Baumann D, Grafe HJ, Beck R, Wurmehl S, Büchner B, Hess C.

Sci Rep. 2016 Jun 14;6:27926. doi: 10.1038/srep27926.

33.

Functional genomics analyses of RNA-binding proteins reveal the splicing regulator SNRPB as an oncogenic candidate in glioblastoma.

Correa BR, de Araujo PR, Qiao M, Burns SC, Chen C, Schlegel R, Agarwal S, Galante PA, Penalva LO.

Genome Biol. 2016 Jun 10;17(1):125. doi: 10.1186/s13059-016-0990-4.

34.

Animal Magnetism: Metaphoric Cues Alter Perceptions of Romantic Partners and Relationships.

Christy AG, Hirsch KA, Schlegel RJ.

PLoS One. 2016 May 26;11(5):e0155943. doi: 10.1371/journal.pone.0155943. eCollection 2016.

35.

Characterization of Rat Meibomian Gland Ion and Fluid Transport.

Yu D, Davis RM, Aita M, Burns KA, Clapp PW, Gilmore RC, Chua M, O'Neal WK, Schlegel R, Randell SH, C Boucher R.

Invest Ophthalmol Vis Sci. 2016 Apr 1;57(4):2328-43. doi: 10.1167/iovs.15-17945.

36.

Maternal hypomagnesemia alters renal function but does not program changes in the cardiovascular physiology of adult offspring.

Schlegel RN, Moritz KM, Paravicini TM.

J Dev Orig Health Dis. 2016 Oct;7(5):473-480. Epub 2016 Mar 28.

PMID:
27019320
37.

Correction: Gene Expression Ratios Lead to Accurate and Translatable Predictors of DR5 Agonism across Multiple Tumor Lineages.

Reddy A, Growney JD, Wilson NS, Emery CM, Johnson JA, Ward R, Monaco KA, Korn J, Monahan JE, Stump MD, Mapa FA, Wilson CJ, Steiger J, Ledell J, Rickles RJ, Myer VE, Ettenberg SA, Schlegel R, Sellers WR, Huet HA, Lehár J.

PLoS One. 2016 Jan 5;11(1):e0146635. doi: 10.1371/journal.pone.0146635. eCollection 2016. No abstract available.

38.

Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications.

Ao Z, Parasido E, Rawal S, Williams A, Schlegel R, Liu S, Albanese C, Cote RJ, Agarwal A, Datar RH.

Lab Chip. 2015 Nov 21;15(22):4277-82. doi: 10.1039/c5lc01024a.

39.

Gene Expression Ratios Lead to Accurate and Translatable Predictors of DR5 Agonism across Multiple Tumor Lineages.

Reddy A, Growney JD, Wilson NS, Emery CM, Johnson JA, Ward R, Monaco KA, Korn J, Monahan JE, Stump MD, Mapa FA, Wilson CJ, Steiger J, Ledell J, Rickles RJ, Myer VE, Ettenberg SA, Schlegel R, Sellers WR, Huet HA, Lehár J.

PLoS One. 2015 Sep 17;10(9):e0138486. doi: 10.1371/journal.pone.0138486. eCollection 2015. Erratum in: PLoS One. 2016;11(1):e0146635.

40.

Patterns of HER2 Gene Amplification and Response to Anti-HER2 Therapies.

Vicario R, Peg V, Morancho B, Zacarias-Fluck M, Zhang J, Martínez-Barriocanal Á, Navarro Jiménez A, Aura C, Burgues O, Lluch A, Cortés J, Nuciforo P, Rubio IT, Marangoni E, Deeds J, Boehm M, Schlegel R, Tabernero J, Mosher R, Arribas J.

PLoS One. 2015 Jun 15;10(6):e0129876. doi: 10.1371/journal.pone.0129876. eCollection 2015.

41.

Neurocognitive performance and prior injury among U.S. Department of Defense military personnel.

Proctor SP, Nieto K, Heaton KJ, Dillon CC, Schlegel RE, Russell ML, Vincent AS.

Mil Med. 2015 Jun;180(6):660-9. doi: 10.7205/MILMED-D-14-00298.

PMID:
26032381
42.

Silver Indium Telluride Semiconductors and Their Solid Solutions with Cadmium Indium Telluride: Structure and Physical Properties.

Welzmiller S, Hennersdorf F, Schlegel R, Fitch A, Wagner G, Oeckler O.

Inorg Chem. 2015 Jun 15;54(12):5745-56. doi: 10.1021/acs.inorgchem.5b00433. Epub 2015 May 29.

PMID:
26023890
43.

Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors.

Frampton GM, Ali SM, Rosenzweig M, Chmielecki J, Lu X, Bauer TM, Akimov M, Bufill JA, Lee C, Jentz D, Hoover R, Ou SH, Salgia R, Brennan T, Chalmers ZR, Jaeger S, Huang A, Elvin JA, Erlich R, Fichtenholtz A, Gowen KA, Greenbowe J, Johnson A, Khaira D, McMahon C, Sanford EM, Roels S, White J, Greshock J, Schlegel R, Lipson D, Yelensky R, Morosini D, Ross JS, Collisson E, Peters M, Stephens PJ, Miller VA.

Cancer Discov. 2015 Aug;5(8):850-9. doi: 10.1158/2159-8290.CD-15-0285. Epub 2015 May 13.

44.

Complete genome sequence of canine papillomavirus type 16.

Luff J, Mader M, Britton M, Fass J, Rowland P, Orr C, Schlegel R, Yuan H.

Genome Announc. 2015 May 7;3(3). pii: e00404-15. doi: 10.1128/genomeA.00404-15.

45.

Maternal hypomagnesemia causes placental abnormalities and fetal and postnatal mortality.

Schlegel RN, Cuffe JS, Moritz KM, Paravicini TM.

Placenta. 2015 Jul;36(7):750-8. doi: 10.1016/j.placenta.2015.03.011. Epub 2015 Apr 11.

PMID:
25924939
46.

Complete genome sequence of canine papillomavirus virus type 12.

Zhou D, Luff J, Paul S, Alkhilaiwi F, Usuda Y, Wang N, Affolter V, Moore P, Schlegel R, Yuan H.

Genome Announc. 2015 Apr 16;3(2). pii: e00294-15. doi: 10.1128/genomeA.00294-15.

47.

Explaining Extremity in Evaluation of Group Members: Meta-Analytic Tests of Three Theories.

Bettencourt BA, Manning M, Molix L, Schlegel R, Eidelman S, Biernat M.

Pers Soc Psychol Rev. 2016 Feb;20(1):49-74. doi: 10.1177/1088868315574461. Epub 2015 Mar 13.

PMID:
25770087
48.

Loss of Tuberous Sclerosis Complex 2 (TSC2) Is Frequent in Hepatocellular Carcinoma and Predicts Response to mTORC1 Inhibitor Everolimus.

Huynh H, Hao HX, Chan SL, Chen D, Ong R, Soo KC, Pochanard P, Yang D, Ruddy D, Liu M, Derti A, Balak MN, Palmer MR, Wang Y, Lee BH, Sellami D, Zhu AX, Schlegel R, Huang A.

Mol Cancer Ther. 2015 May;14(5):1224-35. doi: 10.1158/1535-7163.MCT-14-0768. Epub 2015 Feb 27.

49.

FGFR-Mediated Reactivation of MAPK Signaling Attenuates Antitumor Effects of Imatinib in Gastrointestinal Stromal Tumors.

Li F, Huynh H, Li X, Ruddy DA, Wang Y, Ong R, Chow P, Qiu S, Tam A, Rakiec DP, Schlegel R, Monahan JE, Huang A.

Cancer Discov. 2015 Apr;5(4):438-51. doi: 10.1158/2159-8290.CD-14-0763. Epub 2015 Feb 11.

50.

The identification and characterization of a STAT5 gene signature in hematologic malignancies.

Sonkin D, Palmer M, Rong X, Horrigan K, Regnier CH, Fanton C, Holash J, Pinzon-Ortiz M, Squires M, Sirulnik A, Radimerski T, Schlegel R, Morrissey M, Cao ZA.

Cancer Biomark. 2015;15(1):79-87. doi: 10.3233/CBM-140434.

PMID:
25524945

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