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Treatment of Peri-implantitis-Electrolytic Cleaning Versus Mechanical and Electrolytic Cleaning-A Randomized Controlled Clinical Trial-Six-Month Results.

Schlee M, Rathe F, Brodbeck U, Ratka C, Weigl P, Zipprich H.

J Clin Med. 2019 Nov 7;8(11). pii: E1909. doi: 10.3390/jcm8111909.


Photo-activated implants: a triple-blinded, split-mouth, randomized controlled clinical trial on the resistance to removal torque at various healing intervals.

Puisys A, Schlee M, Linkevicius T, Petrakakis P, Tjaden A.

Clin Oral Investig. 2019 Sep 11. doi: 10.1007/s00784-019-03041-5. [Epub ahead of print]


The Effect of In Vitro Electrolytic Cleaning on Biofilm-Contaminated Implant Surfaces.

Ratka C, Weigl P, Henrich D, Koch F, Schlee M, Zipprich H.

J Clin Med. 2019 Sep 6;8(9). pii: E1397. doi: 10.3390/jcm8091397.


Human TLR8 Senses RNA From Plasmodium falciparum-Infected Red Blood Cells Which Is Uniquely Required for the IFN-γ Response in NK Cells.

Coch C, Hommertgen B, Zillinger T, Daßler-Plenker J, Putschli B, Nastaly M, Kümmerer BM, Scheunemann JF, Schumak B, Specht S, Schlee M, Barchet W, Hoerauf A, Bartok E, Hartmann G.

Front Immunol. 2019 Mar 27;10:371. doi: 10.3389/fimmu.2019.00371. eCollection 2019.


Implant success and survival rates in daily dental practice: 5-year results of a non-interventional study using CAMLOG SCREW-LINE implants with or without platform-switching abutments.

Beschnidt SM, Cacaci C, Dedeoglu K, Hildebrand D, Hulla H, Iglhaut G, Krennmair G, Schlee M, Sipos P, Stricker A, Ackermann KL.

Int J Implant Dent. 2018 Nov 2;4(1):33. doi: 10.1186/s40729-018-0145-3.


A non-interventional multicenter study to document the implants success and survival rates in daily dental practices of the CONELOG screw-line implant.

Cacaci C, Ackermann KL, Barth T, Kistler S, Stiller M, Schlee M.

Clin Oral Investig. 2019 Jun;23(6):2609-2616. doi: 10.1007/s00784-018-2646-0. Epub 2018 Oct 15.


SOCS1 and SOCS3 Target IRF7 Degradation To Suppress TLR7-Mediated Type I IFN Production of Human Plasmacytoid Dendritic Cells.

Yu CF, Peng WM, Schlee M, Barchet W, Eis-Hübinger AM, Kolanus W, Geyer M, Schmitt S, Steinhagen F, Oldenburg J, Novak N.

J Immunol. 2018 Jun 15;200(12):4024-4035. doi: 10.4049/jimmunol.1700510. Epub 2018 Apr 30.


Allogeneic bone block for challenging augmentation-a clinical, histological, and histomorphometrical investigation of tissue reaction and new bone formation.

Lorenz J, Kubesch A, Al-Maawi S, Schwarz F, Sader RA, Schlee M, Ghanaati S.

Clin Oral Investig. 2018 Dec;22(9):3159-3169. doi: 10.1007/s00784-018-2407-0. Epub 2018 Mar 9.


Self-assembling peptide matrix for treatment of dentin hypersensitivity: A randomized controlled clinical trial.

Schlee M, Rathe F, Bommer C, Bröseler F, Kind L.

J Periodontol. 2018 Jun;89(6):653-660. doi: 10.1002/JPER.17-0429. Epub 2018 May 16.


Clinical performance of self-assembling peptide P11 -4 in the treatment of initial proximal carious lesions: A practice-based case series.

Schlee M, Schad T, Koch JH, Cattin PC, Rathe F.

J Investig Clin Dent. 2018 Feb;9(1). doi: 10.1111/jicd.12286. Epub 2017 Sep 3.


Variant Purification of an Allogeneic Bone Block.

Lorenz J, Schlee M, Al-Maawi S, Chia P, Sader RA, Ghanaati S.

Acta Stomatol Croat. 2017 Jun;51(2):141-147. doi: 10.15644/asc51/2/7.


RIG-I Activation Protects and Rescues from Lethal Influenza Virus Infection and Bacterial Superinfection.

Coch C, Stümpel JP, Lilien-Waldau V, Wohlleber D, Kümmerer BM, Bekeredjian-Ding I, Kochs G, Garbi N, Herberhold S, Schuberth-Wagner C, Ludwig J, Barchet W, Schlee M, Hoerauf A, Bootz F, Staeheli P, Hartmann G, Hartmann E.

Mol Ther. 2017 Sep 6;25(9):2093-2103. doi: 10.1016/j.ymthe.2017.07.003. Epub 2017 Jul 8.


RIG-I Resists Hypoxia-Induced Immunosuppression and Dedifferentiation.

Engel C, Brügmann G, Lambing S, Mühlenbeck LH, Marx S, Hagen C, Horváth D, Goldeck M, Ludwig J, Herzner AM, Drijfhout JW, Wenzel D, Coch C, Tüting T, Schlee M, Hornung V, Hartmann G, Van den Boorn JG.

Cancer Immunol Res. 2017 Jun;5(6):455-467. doi: 10.1158/2326-6066.CIR-16-0129-T. Epub 2017 May 3.


Dimensional Evaluation of Different Ridge Preservation Techniques: A Randomized Clinical Study.

Fickl S, Fischer K, Petersen N, Happe A, Schlee M, Schlagenhauf U, Kebschull M.

Int J Periodontics Restorative Dent. 2017 May/Jun;37(3):403-410. doi: 10.11607/prd.2629.


G-rich DNA-induced stress response blocks type-I-IFN but not CXCL10 secretion in monocytes.

Herzner AM, Wolter S, Zillinger T, Schmitz S, Barchet W, Hartmann G, Bartok E, Schlee M.

Sci Rep. 2016 Dec 12;6:38405. doi: 10.1038/srep38405.


RIG-I activation induces the release of extracellular vesicles with antitumor activity.

Daßler-Plenker J, Reiners KS, van den Boorn JG, Hansen HP, Putschli B, Barnert S, Schuberth-Wagner C, Schubert R, Tüting T, Hallek M, Schlee M, Hartmann G, Pogge von Strandmann E, Coch C.

Oncoimmunology. 2016 Aug 19;5(10):e1219827. eCollection 2016.


Discriminating self from non-self in nucleic acid sensing.

Schlee M, Hartmann G.

Nat Rev Immunol. 2016 Sep;16(9):566-80. doi: 10.1038/nri.2016.78. Epub 2016 Jul 25. Review.


The influence of various rehydration protocols on biomechanical properties of different acellular tissue matrices.

Kasaj A, Levin L, Stratul SI, Götz H, Schlee M, Rütters CB, Konerding MA, Ackermann M, Willershausen B, Pabst AM.

Clin Oral Investig. 2016 Jul;20(6):1303-15. doi: 10.1007/s00784-015-1614-1. Epub 2015 Oct 5.


International Brainstorming Meeting on Etiologic and Risk Factors of Peri-implantitis, Montegrotto (Padua, Italy), August 2014.

Canullo L, Schlee M, Wagner W, Covani U; Montegrotto Group for the Study of Peri-implant Disease.

Int J Oral Maxillofac Implants. 2015 Sep-Oct;30(5):1093-104. doi: 10.11607/jomi.4386.


Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA.

Herzner AM, Hagmann CA, Goldeck M, Wolter S, Kübler K, Wittmann S, Gramberg T, Andreeva L, Hopfner KP, Mertens C, Zillinger T, Jin T, Xiao TS, Bartok E, Coch C, Ackermann D, Hornung V, Ludwig J, Barchet W, Hartmann G, Schlee M.

Nat Immunol. 2015 Oct;16(10):1025-33. doi: 10.1038/ni.3267. Epub 2015 Sep 7.


A Conserved Histidine in the RNA Sensor RIG-I Controls Immune Tolerance to N1-2'O-Methylated Self RNA.

Schuberth-Wagner C, Ludwig J, Bruder AK, Herzner AM, Zillinger T, Goldeck M, Schmidt T, Schmid-Burgk JL, Kerber R, Wolter S, Stümpel JP, Roth A, Bartok E, Drosten C, Coch C, Hornung V, Barchet W, Kümmerer BM, Hartmann G, Schlee M.

Immunity. 2015 Jul 21;43(1):41-51. doi: 10.1016/j.immuni.2015.06.015. Epub 2015 Jul 14.


Histologic characterization of human extraction sockets 3 years after grafting: a case report.

Schlee M, Seitz O, Sader R.

Int J Periodontics Restorative Dent. 2015 May-Jun;35(3):381-6. doi: 10.11607/prd.1680.


Treatment of multiple recessions by means of a collagen matrix: a case series.

Schlee M, Lex M, Rathe F, Kasaj A, Sader R.

Int J Periodontics Restorative Dent. 2014 Nov-Dec;34(6):817-23. doi: 10.11607/prd.2094.


Vertical ridge augmentation using the modified shell technique--a case series.

Stimmelmayr M, Beuer F, Schlee M, Edelhoff D, Güth JF.

Br J Oral Maxillofac Surg. 2014 Dec;52(10):945-50. doi: 10.1016/j.bjoms.2014.08.009. Epub 2014 Sep 26.


Prospective, Multicenter Evaluation of Trabecular Metal-Enhanced Titanium Dental Implants Placed in Routine Dental Practices: 1-Year Interim Report From the Development Period (2010 to 2011).

Schlee M, Pradies G, Mehmke WU, Beneytout A, Stamm M, Meda RG, Kamm T, Poiroux F, Weinlich F, del Canto Pingarron M, Crichton E, Poulet JB, Bousquet P.

Clin Implant Dent Relat Res. 2015 Dec;17(6):1141-53. doi: 10.1111/cid.12232. Epub 2014 Sep 2.


Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates.

Goubau D, Schlee M, Deddouche S, Pruijssers AJ, Zillinger T, Goldeck M, Schuberth C, Van der Veen AG, Fujimura T, Rehwinkel J, Iskarpatyoti JA, Barchet W, Ludwig J, Dermody TS, Hartmann G, Reis e Sousa C.

Nature. 2014 Oct 16;514(7522):372-375. doi: 10.1038/nature13590. Epub 2014 Aug 10.


High-Temperature Sintering of Xenogeneic Bone Substitutes Leads to Increased Multinucleated Giant Cell Formation: In Vivo and Preliminary Clinical Results.

Barbeck M, Udeabor S, Lorenz J, Schlee M, Holthaus MG, Raetscho N, Choukroun J, Sader R, Kirkpatrick CJ, Ghanaati S.

J Oral Implantol. 2015 Oct;41(5):e212-22. doi: 10.1563/aaid-joi-D-14-00168. Epub 2014 Aug 8.


Enzymatic synthesis and purification of a defined RIG-I ligand.

Goldeck M, Schlee M, Hartmann G, Hornung V.

Methods Mol Biol. 2014;1169:15-25. doi: 10.1007/978-1-4939-0882-0_2.


Esthetic outcome of implant-based reconstructions in augmented bone: comparison of autologous and allogeneic bone block grafting with the pink esthetic score (PES).

Schlee M, Dehner JF, Baukloh K, Happe A, Seitz O, Sader R.

Head Face Med. 2014 May 28;10:21. doi: 10.1186/1746-160X-10-21.


Vertical ridge augmentation using the modified shell technique--a case report.

Stimmelmayr M, Güth JF, Schlee M, Beuer F.

J Oral Maxillofac Surg. 2014 Feb;72(2):286-91. doi: 10.1016/j.joms.2013.09.004.


Crestal Bone Stability around Implants with Horizontally Matching Connection after Soft Tissue Thickening: A Prospective Clinical Trial.

Linkevicius T, Puisys A, Linkeviciene L, Peciuliene V, Schlee M.

Clin Implant Dent Relat Res. 2015 Jun;17(3):497-508. doi: 10.1111/cid.12155. Epub 2013 Sep 17.


A human in vitro whole blood assay to predict the systemic cytokine response to therapeutic oligonucleotides including siRNA.

Coch C, Lück C, Schwickart A, Putschli B, Renn M, Höller T, Barchet W, Hartmann G, Schlee M.

PLoS One. 2013 Aug 5;8(8):e71057. doi: 10.1371/journal.pone.0071057. Print 2013.


Immediate loading of trabecular metal-enhanced titanium dental implants: interim results from an international proof-of-principle study.

Schlee M, van der Schoor WP, van der Schoor AR.

Clin Implant Dent Relat Res. 2015 Jan;17 Suppl 1:e308-20. doi: 10.1111/cid.12127. Epub 2013 Jul 30.


Master sensors of pathogenic RNA - RIG-I like receptors.

Schlee M.

Immunobiology. 2013 Nov;218(11):1322-35. doi: 10.1016/j.imbio.2013.06.007. Epub 2013 Jul 1. Review.


RIG-I detects triphosphorylated RNA of Listeria monocytogenes during infection in non-immune cells.

Hagmann CA, Herzner AM, Abdullah Z, Zillinger T, Jakobs C, Schuberth C, Coch C, Higgins PG, Wisplinghoff H, Barchet W, Hornung V, Hartmann G, Schlee M.

PLoS One. 2013 Apr 30;8(4):e62872. doi: 10.1371/journal.pone.0062872. Print 2013.


Ridge augmentation using customized allogenic bone blocks: proof of concept and histological findings.

Schlee M, Rothamel D.

Implant Dent. 2013 Jun;22(3):212-8. doi: 10.1097/ID.0b013e3182885fa1.


Targeting the cytosolic innate immune receptors RIG-I and MDA5 effectively counteracts cancer cell heterogeneity in glioblastoma.

Glas M, Coch C, Trageser D, Dassler J, Simon M, Koch P, Mertens J, Quandel T, Gorris R, Reinartz R, Wieland A, Von Lehe M, Pusch A, Roy K, Schlee M, Neumann H, Fimmers R, Herrlinger U, Brüstle O, Hartmann G, Besch R, Scheffler B.

Stem Cells. 2013 Jun;31(6):1064-74. doi: 10.1002/stem.1350.


Surgical management of peri-implant soft tissue color mismatch caused by shine-through effects of restorative materials: one-year follow-up.

Happe A, Stimmelmayr M, Schlee M, Rothamel D.

Int J Periodontics Restorative Dent. 2013 Jan-Feb;33(1):81-8.


Clinical study evaluating the discrepancy of two different impression techniques of four implants in an edentulous jaw.

Stimmelmayr M, Güth JF, Erdelt K, Happe A, Schlee M, Beuer F.

Clin Oral Investig. 2013 Nov;17(8):1929-35. doi: 10.1007/s00784-012-0885-z. Epub 2012 Dec 6.


RIG-I detects infection with live Listeria by sensing secreted bacterial nucleic acids.

Abdullah Z, Schlee M, Roth S, Mraheil MA, Barchet W, Böttcher J, Hain T, Geiger S, Hayakawa Y, Fritz JH, Civril F, Hopfner KP, Kurts C, Ruland J, Hartmann G, Chakraborty T, Knolle PA.

EMBO J. 2012 Nov 5;31(21):4153-64. doi: 10.1038/emboj.2012.274. Epub 2012 Oct 12.


Exosomes as nucleic acid nanocarriers.

van den Boorn JG, Dassler J, Coch C, Schlee M, Hartmann G.

Adv Drug Deliv Rev. 2013 Mar;65(3):331-5. doi: 10.1016/j.addr.2012.06.011. Epub 2012 Jun 28. Review.


Bovine pericardium based non-cross linked collagen matrix for successful root coverage, a clinical study in human.

Schlee M, Ghanaati S, Willershausen I, Stimmlmayr M, Sculean A, Sader RA.

Head Face Med. 2012 Mar 5;8:6. doi: 10.1186/1746-160X-8-6.


Use of a modified shell technique for three-dimensional bone grafting: description of a technique.

Stimmelmayr M, Güth JF, Schlee M, Göhring TN, Beuer F.

Aust Dent J. 2012 Mar;57(1):93-7. doi: 10.1111/j.1834-7819.2011.01646.x.


Teeth and posture.

Schunke S, Enssle A, Kreisl A, Schlee M.

Eur J Esthet Dent. 2011 Winter;6(4):406-27.


The influence of enamel matrix derivative on the angiogenic activity of primary endothelial cells.

Kasaj A, Meister J, Lehmann K, Stratul SI, Schlee M, Stein JM, Willershausen B, Schmidt M.

J Periodontal Res. 2012 Aug;47(4):479-87. doi: 10.1111/j.1600-0765.2011.01456.x. Epub 2011 Dec 29.


Delivery with polycations extends the immunostimulant Ribomunyl into a potent antiviral Toll-like receptor 7/8 agonist.

Herberhold S, Coch C, Zillinger T, Hommertgen B, Busch N, Schuberth C, Hartmann E, Wimmenauer V, Hagmann CA, Lüdenbach B, Schlee M, Bootz F, Hartmann G, Barchet W.

Antivir Ther. 2011;16(5):751-8. doi: 10.3851/IMP1822.


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