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Items: 15


The Retinitis Pigmentosa-Linked Mutations in Transmembrane Helix 5 of Rhodopsin Disrupt Cellular Trafficking Regardless of Oligomerization State.

Mallory DP, Gutierrez E, Pinkevitch M, Klinginsmith C, Comar WD, Roushar FJ, Schlebach JP, Smith AW, Jastrzebska B.

Biochemistry. 2018 Sep 4;57(35):5188-5201. doi: 10.1021/acs.biochem.8b00403. Epub 2018 Aug 21.


Bicelle size modulates the rate of bacteriorhodopsin folding.

Gruenhagen TC, Ziarek JJ, Schlebach JP.

Protein Sci. 2018 Jun;27(6):1109-1112. doi: 10.1002/pro.3414. Epub 2018 Apr 25.


Peripheral myelin protein 22 alters membrane architecture.

Mittendorf KF, Marinko JT, Hampton CM, Ke Z, Hadziselimovic A, Schlebach JP, Law CL, Li J, Wright ER, Sanders CR, Ohi MD.

Sci Adv. 2017 Jul 5;3(7):e1700220. doi: 10.1126/sciadv.1700220. eCollection 2017 Jul.


A pH-Mediated Topological Switch within the N-Terminal Domain of Human Caveolin-3.

Kim JH, Schlebach JP, Lu Z, Peng D, Reasoner KC, Sanders CR.

Biophys J. 2016 Jun 7;110(11):2475-2485. doi: 10.1016/j.bpj.2016.05.004.


Topologically Diverse Human Membrane Proteins Partition to Liquid-Disordered Domains in Phase-Separated Lipid Vesicles.

Schlebach JP, Barrett PJ, Day CA, Kim JH, Kenworthy AK, Sanders CR.

Biochemistry. 2016 Feb 23;55(7):985-8. doi: 10.1021/acs.biochem.5b01154. Epub 2016 Feb 11.


Conformational Stability and Pathogenic Misfolding of the Integral Membrane Protein PMP22.

Schlebach JP, Narayan M, Alford C, Mittendorf KF, Carter BD, Li J, Sanders CR.

J Am Chem Soc. 2015 Jul 15;137(27):8758-68. doi: 10.1021/jacs.5b03743. Epub 2015 Jul 2.


The safety dance: biophysics of membrane protein folding and misfolding in a cellular context.

Schlebach JP, Sanders CR.

Q Rev Biophys. 2015 Feb;48(1):1-34. doi: 10.1017/S0033583514000110. Epub 2014 Nov 25.


Bacteriorhodopsin folds through a poorly organized transition state.

Schlebach JP, Woodall NB, Bowie JU, Park C.

J Am Chem Soc. 2014 Nov 26;136(47):16574-81. doi: 10.1021/ja508359n. Epub 2014 Nov 17.


Influence of Pathogenic Mutations on the Energetics of Translocon-Mediated Bilayer Integration of Transmembrane Helices.

Schlebach JP, Sanders CR.

J Membr Biol. 2015 Jun;248(3):371-81. doi: 10.1007/s00232-014-9726-0. Epub 2014 Sep 6.


Modest effects of lipid modifications on the structure of caveolin-3.

Kim JH, Peng D, Schlebach JP, Hadziselimovic A, Sanders CR.

Biochemistry. 2014 Jul 15;53(27):4320-2. doi: 10.1021/bi5005238. Epub 2014 Jun 26.


Reversible folding of human peripheral myelin protein 22, a tetraspan membrane protein.

Schlebach JP, Peng D, Kroncke BM, Mittendorf KF, Narayan M, Carter BD, Sanders CR.

Biochemistry. 2013 May 14;52(19):3229-41. doi: 10.1021/bi301635f. Epub 2013 May 2.


Simplified proteomics approach to discover protein-ligand interactions.

Chang Y, Schlebach JP, VerHeul RA, Park C.

Protein Sci. 2012 Sep;21(9):1280-7. doi: 10.1002/pro.2112. Epub 2012 Jul 23.


Revisiting the folding kinetics of bacteriorhodopsin.

Schlebach JP, Cao Z, Bowie JU, Park C.

Protein Sci. 2012 Jan;21(1):97-106. doi: 10.1002/pro.766. Epub 2011 Dec 5.


Thermodynamic stability of bacteriorhodopsin mutants measured relative to the bacterioopsin unfolded state.

Cao Z, Schlebach JP, Park C, Bowie JU.

Biochim Biophys Acta. 2012 Apr;1818(4):1049-54. doi: 10.1016/j.bbamem.2011.08.019. Epub 2011 Aug 22.


Probing membrane protein unfolding with pulse proteolysis.

Schlebach JP, Kim MS, Joh NH, Bowie JU, Park C.

J Mol Biol. 2011 Mar 4;406(4):545-51. doi: 10.1016/j.jmb.2010.12.018. Epub 2010 Dec 28. Review.

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