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Items: 27


Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors.

O'Connor CM, Leonard D, Wiredja D, Avelar RA, Wang Z, Schlatzer D, Bryson B, Tokala E, Taylor SE, Upadhyay A, Sangodkar J, Gingras AC, Westermarck J, Xu W, DiFeo A, Brautigan DL, Haider S, Jackson M, Narla G.

Oncogene. 2019 Sep 20. doi: 10.1038/s41388-019-1012-2. [Epub ahead of print]


Proteomic Investigations of Autism Brain Identify Known and Novel Pathogenetic Processes.

Abraham JR, Szoko N, Barnard J, Rubin RA, Schlatzer D, Lundberg K, Li X, Natowicz MR.

Sci Rep. 2019 Sep 11;9(1):13118. doi: 10.1038/s41598-019-49533-y.


Xenointoxication of a Rabbit for the Control of the Common Bed Bug Cimex lectularius L. Using Ivermectin.

Ridge GE, Elmer W, Gaines S, Li X, Schlatzer D, McClure-Brinton K, Sheele JM.

Scientifica (Cairo). 2019 Feb 27;2019:4793569. doi: 10.1155/2019/4793569. eCollection 2019.


CoPhosK: A method for comprehensive kinase substrate annotation using co-phosphorylation analysis.

Ayati M, Wiredja D, Schlatzer D, Maxwell S, Li M, Koyutürk M, Chance MR.

PLoS Comput Biol. 2019 Feb 27;15(2):e1006678. doi: 10.1371/journal.pcbi.1006678. eCollection 2019 Feb.


Small-Molecule Activators of Protein Phosphatase 2A for the Treatment of Castration-Resistant Prostate Cancer.

McClinch K, Avelar RA, Callejas D, Izadmehr S, Wiredja D, Perl A, Sangodkar J, Kastrinsky DB, Schlatzer D, Cooper M, Kiselar J, Stachnik A, Yao S, Hoon D, McQuaid D, Zaware N, Gong Y, Brautigan DL, Plymate SR, Sprenger CCT, Oh WK, Levine AC, Kirschenbaum A, Sfakianos JP, Sears R, DiFeo A, Ioannou Y, Ohlmeyer M, Narla G, Galsky MD.

Cancer Res. 2018 Apr 15;78(8):2065-2080. doi: 10.1158/0008-5472.CAN-17-0123. Epub 2018 Jan 22.


Phosphoproteomics Profiling of Nonsmall Cell Lung Cancer Cells Treated with a Novel Phosphatase Activator.

Wiredja DD, Ayati M, Mazhar S, Sangodkar J, Maxwell S, Schlatzer D, Narla G, Koyutürk M, Chance MR.

Proteomics. 2017 Nov;17(22). doi: 10.1002/pmic.201700214. Epub 2017 Oct 25. Erratum in: Proteomics. 2018 Dec;18(24):e1870214.


A novel microduplication of ARID1B: Clinical, genetic, and proteomic findings.

Seabra CM, Szoko N, Erdin S, Ragavendran A, Stortchevoi A, Maciel P, Lundberg K, Schlatzer D, Smith J, Talkowski ME, Gusella JF, Natowicz MR.

Am J Med Genet A. 2017 Sep;173(9):2478-2484. doi: 10.1002/ajmg.a.38327. Epub 2017 Jul 10.


Proteomic profiling of the hypothalamus in two mouse models of narcolepsy.

Azzam S, Schlatzer D, Nethery D, Saleh D, Li X, Akladious A, Chance MR, Strohl KP.

Proteomics. 2017 Jul;17(13-14). doi: 10.1002/pmic.201600478. Epub 2017 Jun 26.


Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth.

Sangodkar J, Perl A, Tohme R, Kiselar J, Kastrinsky DB, Zaware N, Izadmehr S, Mazhar S, Wiredja DD, O'Connor CM, Hoon D, Dhawan NS, Schlatzer D, Yao S, Leonard D, Borczuk AC, Gokulrangan G, Wang L, Svenson E, Farrington CC, Yuan E, Avelar RA, Stachnik A, Smith B, Gidwani V, Giannini HM, McQuaid D, McClinch K, Wang Z, Levine AC, Sears RC, Chen EY, Duan Q, Datt M, Haider S, Ma'ayan A, DiFeo A, Sharma N, Galsky MD, Brautigan DL, Ioannou YA, Xu W, Chance MR, Ohlmeyer M, Narla G.

J Clin Invest. 2017 Jun 1;127(6):2081-2090. doi: 10.1172/JCI89548. Epub 2017 May 15.


A Targeted Mass Spectrometry Assay for Detection of HIV Gag Protein Following Induction of Latent Viral Reservoirs.

Schlatzer D, Haqqani AA, Li X, Dobrowolski C, Chance MR, Tilton JC.

Anal Chem. 2017 May 16;89(10):5325-5332. doi: 10.1021/acs.analchem.6b05070. Epub 2017 May 3.


Proteome and Protein Network Analyses of Memory T Cells Find Altered Translation and Cell Stress Signaling in Treated Human Immunodeficiency Virus Patients Exhibiting Poor CD4 Recovery.

Azzam S, Schlatzer D, Maxwell S, Li X, Bazdar D, Chen Y, Asaad R, Barnholtz-Sloan J, Chance MR, Sieg SF.

Open Forum Infect Dis. 2016 Mar 15;3(2):ofw037. doi: 10.1093/ofid/ofw037. eCollection 2016 Mar.


HIV signaling through CD4 and CCR5 activates Rho family GTPases that are required for optimal infection of primary CD4+ T cells.

Lucera MB, Fleissner Z, Tabler CO, Schlatzer DM, Troyer Z, Tilton JC.

Retrovirology. 2017 Jan 24;14(1):4. doi: 10.1186/s12977-017-0328-7.


During Hepatitis C Virus (HCV) Infection and HCV-HIV Coinfection, an Elevated Plasma Level of Autotaxin Is Associated With Lysophosphatidic Acid and Markers of Immune Activation That Normalize During Interferon-Free HCV Therapy.

Kostadinova L, Shive CL, Judge C, Zebrowski E, Compan A, Rife K, Hirsch A, Falck-Ytter Y, Schlatzer DM, Li X, Chance MR, Rodriguez B, Popkin DL, Anthony DD.

J Infect Dis. 2016 Nov 1;214(9):1438-1448. Epub 2016 Aug 17.


Proteomic and bioinformatics profile of paired human alveolar macrophages and peripheral blood monocytes.

Tomechko SE, Lundberg KC, Jarvela J, Bebek G, Chesnokov NG, Schlatzer D, Ewing RM, Boom WH, Chance MR, Silver RF.

Proteomics. 2015 Nov;15(22):3797-805. doi: 10.1002/pmic.201400496.


Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo.

Najm FJ, Madhavan M, Zaremba A, Shick E, Karl RT, Factor DC, Miller TE, Nevin ZS, Kantor C, Sargent A, Quick KL, Schlatzer DM, Tang H, Papoian R, Brimacombe KR, Shen M, Boxer MB, Jadhav A, Robinson AP, Podojil JR, Miller SD, Miller RH, Tesar PJ.

Nature. 2015 Jun 11;522(7555):216-20. doi: 10.1038/nature14335. Epub 2015 Apr 20.


Tissue specific dysregulated protein subnetworks in type 2 diabetic bladder urothelium and detrusor muscle.

Tomechko SE, Liu G, Tao M, Schlatzer D, Powell CT, Gupta S, Chance MR, Daneshgari F.

Mol Cell Proteomics. 2015 Mar;14(3):635-45. doi: 10.1074/mcp.M114.041863. Epub 2015 Jan 8.


Proteomics of skin proteins in psoriasis: from discovery and verification in a mouse model to confirmation in humans.

Lundberg KC, Fritz Y, Johnston A, Foster AM, Baliwag J, Gudjonsson JE, Schlatzer D, Gokulrangan G, McCormick TS, Chance MR, Ward NL.

Mol Cell Proteomics. 2015 Jan;14(1):109-19. doi: 10.1074/mcp.M114.042242. Epub 2014 Oct 28.


Human β-defensin 3 induces STAT1 phosphorylation, tyrosine phosphatase activity, and cytokine synthesis in T cells.

Meisch JP, Vogel RM, Schlatzer DM, Li X, Chance MR, Levine AD.

J Leukoc Biol. 2013 Sep;94(3):459-71. doi: 10.1189/jlb.0612300. Epub 2013 Jun 26.


Plasma proteome analysis reveals overlapping, yet distinct mechanisms of immune activation in chronic HCV and HIV infections.

Schlatzer DM, Sugalski JM, Chen Y, Barnholtz-Sloan J, Davitkov P, Hazlett FE, Funderburg N, Rodriguez B, Lederman MM, Sieg SF, Chance MR, Anthony DD.

J Acquir Immune Defic Syndr. 2013 Aug 15;63(5):563-71. doi: 10.1097/QAI.0b013e3182909847.


Pairwise protein expression classifier for candidate biomarker discovery for early detection of human disease prognosis.

Kaur P, Schlatzer D, Cooke K, Chance MR.

BMC Bioinformatics. 2012 Aug 7;13:191. doi: 10.1186/1471-2105-13-191.


Human biomarker discovery and predictive models for disease progression for idiopathic pneumonia syndrome following allogeneic stem cell transplantation.

Schlatzer DM, Dazard JE, Ewing RM, Ilchenko S, Tomcheko SE, Eid S, Ho V, Yanik G, Chance MR, Cooke KR.

Mol Cell Proteomics. 2012 Jun;11(6):M111.015479. doi: 10.1074/mcp.M111.015479. Epub 2012 Feb 15.


Novel urinary protein biomarkers predicting the development of microalbuminuria and renal function decline in type 1 diabetes.

Schlatzer D, Maahs DM, Chance MR, Dazard JE, Li X, Hazlett F, Rewers M, Snell-Bergeon JK.

Diabetes Care. 2012 Mar;35(3):549-55. doi: 10.2337/dc11-1491. Epub 2012 Jan 11.


A quantitative proteomic approach for detecting protein profiles of activated human myeloid dendritic cells.

Schlatzer DM, Sugalski J, Dazard JE, Chance MR, Anthony DD.

J Immunol Methods. 2012 Jan 31;375(1-2):39-45. doi: 10.1016/j.jim.2011.09.004. Epub 2011 Sep 16.


Urinary protein profiles in a rat model for diabetic complications.

Schlatzer DM, Dazard JE, Dharsee M, Ewing RM, Ilchenko S, Stewart I, Christ G, Chance MR.

Mol Cell Proteomics. 2009 Sep;8(9):2145-58. doi: 10.1074/mcp.M800558-MCP200. Epub 2009 Jun 4.


A proteomic analysis of human cilia: identification of novel components.

Ostrowski LE, Blackburn K, Radde KM, Moyer MB, Schlatzer DM, Moseley A, Boucher RC.

Mol Cell Proteomics. 2002 Jun;1(6):451-65.


The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present.

Koc EC, Burkhart W, Blackburn K, Moyer MB, Schlatzer DM, Moseley A, Spremulli LL.

J Biol Chem. 2001 Nov 23;276(47):43958-69. Epub 2001 Sep 10.

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