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Items: 47

1.

Author Correction: Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment.

Li P, Lahvic JL, Binder V, Pugach EK, Riley EB, Tamplin OJ, Panigrahy D, Bowman TV, Barrett FG, Heffner GC, McKinney-Freeman S, Schlaeger TM, Daley GQ, Zeldin DC, Zon LI.

Nature. 2019 Sep;573(7772):E1. doi: 10.1038/s41586-019-1489-4.

PMID:
31435017
2.

Applying Deep Neural Network Analysis to High-Content Image-Based Assays.

Yang SJ, Lipnick SL, Makhortova NR, Venugopalan S, Fan M, Armstrong Z, Schlaeger TM, Deng L, Chung WK, O'Callaghan L, Geraschenko A, Whye D, Berndl M, Hazard J, Williams B, Narayanaswamy A, Ando DM, Nelson P, Rubin LL.

SLAS Discov. 2019 Sep;24(8):829-841. doi: 10.1177/2472555219857715. Epub 2019 Jul 8.

3.

The Lin28/let-7 Pathway Regulates the Mammalian Caudal Body Axis Elongation Program.

Robinton DA, Chal J, Lummertz da Rocha E, Han A, Yermalovich AV, Oginuma M, Schlaeger TM, Sousa P, Rodriguez A, Urbach A, Pourquié O, Daley GQ.

Dev Cell. 2019 Feb 11;48(3):396-405.e3. doi: 10.1016/j.devcel.2018.12.016. Epub 2019 Jan 17.

PMID:
30661985
4.

H3K9 methyltransferases and demethylases control lung tumor-propagating cells and lung cancer progression.

Rowbotham SP, Li F, Dost AFM, Louie SM, Marsh BP, Pessina P, Anbarasu CR, Brainson CF, Tuminello SJ, Lieberman A, Ryeom S, Schlaeger TM, Aronow BJ, Watanabe H, Wong KK, Kim CF.

Nat Commun. 2018 Nov 19;9(1):4559. doi: 10.1038/s41467-018-07077-1.

5.

The ESCRT-III Protein CHMP1A Mediates Secretion of Sonic Hedgehog on a Distinctive Subtype of Extracellular Vesicles.

Coulter ME, Dorobantu CM, Lodewijk GA, Delalande F, Cianferani S, Ganesh VS, Smith RS, Lim ET, Xu CS, Pang S, Wong ET, Lidov HGW, Calicchio ML, Yang E, Gonzalez DM, Schlaeger TM, Mochida GH, Hess H, Lee WA, Lehtinen MK, Kirchhausen T, Haussler D, Jacobs FMJ, Gaudin R, Walsh CA.

Cell Rep. 2018 Jul 24;24(4):973-986.e8. doi: 10.1016/j.celrep.2018.06.100.

6.

Nonintegrating Human Somatic Cell Reprogramming Methods.

Schlaeger TM.

Adv Biochem Eng Biotechnol. 2018;163:1-21. doi: 10.1007/10_2017_29. Review.

PMID:
29075799
7.

A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development.

Ciarlo C, Kaufman CK, Kinikoglu B, Michael J, Yang S, D Amato C, Blokzijl-Franke S, den Hertog J, Schlaeger TM, Zhou Y, Liao E, Zon LI.

Elife. 2017 Aug 23;6. pii: e29145. doi: 10.7554/eLife.29145.

8.

Using CRISPR-Cas9 to Generate Gene-Corrected Autologous iPSCs for the Treatment of Inherited Retinal Degeneration.

Burnight ER, Gupta M, Wiley LA, Anfinson KR, Tran A, Triboulet R, Hoffmann JM, Klaahsen DL, Andorf JL, Jiao C, Sohn EH, Adur MK, Ross JW, Mullins RF, Daley GQ, Schlaeger TM, Stone EM, Tucker BA.

Mol Ther. 2017 Sep 6;25(9):1999-2013. doi: 10.1016/j.ymthe.2017.05.015. Epub 2017 Jun 12.

9.

Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors.

Doulatov S, Vo LT, Macari ER, Wahlster L, Kinney MA, Taylor AM, Barragan J, Gupta M, McGrath K, Lee HY, Humphries JM, DeVine A, Narla A, Alter BP, Beggs AH, Agarwal S, Ebert BL, Gazda HT, Lodish HF, Sieff CA, Schlaeger TM, Zon LI, Daley GQ.

Sci Transl Med. 2017 Feb 8;9(376). pii: eaah5645. doi: 10.1126/scitranslmed.aah5645.

10.

Developmental Vitamin D Availability Impacts Hematopoietic Stem Cell Production.

Cortes M, Chen MJ, Stachura DL, Liu SY, Kwan W, Wright F, Vo LT, Theodore LN, Esain V, Frost IM, Schlaeger TM, Goessling W, Daley GQ, North TE.

Cell Rep. 2016 Oct 4;17(2):458-468. doi: 10.1016/j.celrep.2016.09.012.

11.

Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment.

Li P, Lahvic JL, Binder V, Pugach EK, Riley EB, Tamplin OJ, Panigrahy D, Bowman TV, Barrett FG, Heffner GC, McKinney-Freeman S, Schlaeger TM, Daley GQ, Zeldin DC, Zon LI.

Nature. 2015 Jul 23;523(7561):468-71. doi: 10.1038/nature14569. Erratum in: Nature. 2019 Sep;573(7772):E1.

12.

Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence.

Kim PG, Nakano H, Das PP, Chen MJ, Rowe RG, Chou SS, Ross SJ, Sakamoto KM, Zon LI, Schlaeger TM, Orkin SH, Nakano A, Daley GQ.

J Exp Med. 2015 May 4;212(5):633-48. doi: 10.1084/jem.20141514. Epub 2015 Apr 13.

13.

Adenosine signaling promotes hematopoietic stem and progenitor cell emergence.

Jing L, Tamplin OJ, Chen MJ, Deng Q, Patterson S, Kim PG, Durand EM, McNeil A, Green JM, Matsuura S, Ablain J, Brandt MK, Schlaeger TM, Huttenlocher A, Daley GQ, Ravid K, Zon LI.

J Exp Med. 2015 May 4;212(5):649-63. doi: 10.1084/jem.20141528. Epub 2015 Apr 13.

14.

Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium.

Jang IH, Lu YF, Zhao L, Wenzel PL, Kume T, Datta SM, Arora N, Guiu J, Lagha M, Kim PG, Do EK, Kim JH, Schlaeger TM, Zon LI, Bigas A, Burns CE, Daley GQ.

Blood. 2015 Feb 26;125(9):1418-26. doi: 10.1182/blood-2014-04-568170. Epub 2015 Jan 13.

15.

A comparison of non-integrating reprogramming methods.

Schlaeger TM, Daheron L, Brickler TR, Entwisle S, Chan K, Cianci A, DeVine A, Ettenger A, Fitzgerald K, Godfrey M, Gupta D, McPherson J, Malwadkar P, Gupta M, Bell B, Doi A, Jung N, Li X, Lynes MS, Brookes E, Cherry AB, Demirbas D, Tsankov AM, Zon LI, Rubin LL, Feinberg AP, Meissner A, Cowan CA, Daley GQ.

Nat Biotechnol. 2015 Jan;33(1):58-63. doi: 10.1038/nbt.3070. Epub 2014 Dec 1.

16.

TMEM14C is required for erythroid mitochondrial heme metabolism.

Yien YY, Robledo RF, Schultz IJ, Takahashi-Makise N, Gwynn B, Bauer DE, Dass A, Yi G, Li L, Hildick-Smith GJ, Cooney JD, Pierce EL, Mohler K, Dailey TA, Miyata N, Kingsley PD, Garone C, Hattangadi SM, Huang H, Chen W, Keenan EM, Shah DI, Schlaeger TM, DiMauro S, Orkin SH, Cantor AB, Palis J, Koehler CM, Lodish HF, Kaplan J, Ward DM, Dailey HA, Phillips JD, Peters LL, Paw BH.

J Clin Invest. 2014 Oct;124(10):4294-304. doi: 10.1172/JCI76979. Epub 2014 Aug 26.

17.

Neurotrophin receptor TrkB promotes lung adenocarcinoma metastasis.

Sinkevicius KW, Kriegel C, Bellaria KJ, Lee J, Lau AN, Leeman KT, Zhou P, Beede AM, Fillmore CM, Caswell D, Barrios J, Wong KK, Sholl LM, Schlaeger TM, Bronson RT, Chirieac LR, Winslow MM, Haigis MC, Kim CF.

Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10299-304. doi: 10.1073/pnas.1404399111. Epub 2014 Jun 30.

18.

Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria.

Chung J, Anderson SA, Gwynn B, Deck KM, Chen MJ, Langer NB, Shaw GC, Huston NC, Boyer LF, Datta S, Paradkar PN, Li L, Wei Z, Lambert AJ, Sahr K, Wittig JG, Chen W, Lu W, Galy B, Schlaeger TM, Hentze MW, Ward DM, Kaplan J, Eisenstein RS, Peters LL, Paw BH.

J Biol Chem. 2014 Mar 14;289(11):7835-43. doi: 10.1074/jbc.M114.547778. Epub 2014 Feb 7. Erratum in: J Biol Chem. 2014 May 16;289(20):13707.

19.

iPSC-derived neurons as a higher-throughput readout for autism: promises and pitfalls.

Prilutsky D, Palmer NP, Smedemark-Margulies N, Schlaeger TM, Margulies DM, Kohane IS.

Trends Mol Med. 2014 Feb;20(2):91-104. doi: 10.1016/j.molmed.2013.11.004. Epub 2013 Dec 24. Review.

20.

Pluripotent stem cell models of Shwachman-Diamond syndrome reveal a common mechanism for pancreatic and hematopoietic dysfunction.

Tulpule A, Kelley JM, Lensch MW, McPherson J, Park IH, Hartung O, Nakamura T, Schlaeger TM, Shimamura A, Daley GQ.

Cell Stem Cell. 2013 Jun 6;12(6):727-36. doi: 10.1016/j.stem.2013.04.002. Epub 2013 Apr 18.

21.

Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells.

Lafaille FG, Pessach IM, Zhang SY, Ciancanelli MJ, Herman M, Abhyankar A, Ying SW, Keros S, Goldstein PA, Mostoslavsky G, Ordovas-Montanes J, Jouanguy E, Plancoulaine S, Tu E, Elkabetz Y, Al-Muhsen S, Tardieu M, Schlaeger TM, Daley GQ, Abel L, Casanova JL, Studer L, Notarangelo LD.

Nature. 2012 Nov 29;491(7426):769-73. doi: 10.1038/nature11583. Epub 2012 Oct 28.

22.

Induced pluripotent stem cells as a tool for gaining new insights into Fanconi anemia.

Müller LU, Schlaeger TM, DeVine AL, Williams DA.

Cell Cycle. 2012 Aug 15;11(16):2985-90. doi: 10.4161/cc.21109. Epub 2012 Jul 24.

23.

The mitochondrial transporter ABC-me (ABCB10), a downstream target of GATA-1, is essential for erythropoiesis in vivo.

Hyde BB, Liesa M, Elorza AA, Qiu W, Haigh SE, Richey L, Mikkola HK, Schlaeger TM, Shirihai OS.

Cell Death Differ. 2012 Jul;19(7):1117-26. doi: 10.1038/cdd.2011.195. Epub 2012 Jan 13.

24.

Live-cell immunofluorescence staining of human pluripotent stem cells.

Manos PD, Ratanasirintrawoot S, Loewer S, Daley GQ, Schlaeger TM.

Curr Protoc Stem Cell Biol. 2011 Dec;Chapter 1:Unit 1C.12. doi: 10.1002/9780470151808.sc01c12s19.

PMID:
22135082
25.

Generation of induced pluripotent stem cell lines from human fibroblasts via retroviral gene transfer.

Miller JD, Schlaeger TM.

Methods Mol Biol. 2011;767:55-65. doi: 10.1007/978-1-61779-201-4_5.

PMID:
21822867
26.

A call for standardized naming and reporting of human ESC and iPSC lines.

Luong MX, Auerbach J, Crook JM, Daheron L, Hei D, Lomax G, Loring JF, Ludwig T, Schlaeger TM, Smith KP, Stacey G, Xu RH, Zeng F.

Cell Stem Cell. 2011 Apr 8;8(4):357-9. doi: 10.1016/j.stem.2011.03.002.

27.

Induced pluripotent stem cells: a novel frontier in the study of human primary immunodeficiencies.

Pessach IM, Ordovas-Montanes J, Zhang SY, Casanova JL, Giliani S, Gennery AR, Al-Herz W, Manos PD, Schlaeger TM, Park IH, Rucci F, Agarwal S, Mostoslavsky G, Daley GQ, Notarangelo LD.

J Allergy Clin Immunol. 2011 Jun;127(6):1400-7.e4. doi: 10.1016/j.jaci.2010.11.008. Epub 2010 Dec 24.

28.

Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells.

Loewer S, Cabili MN, Guttman M, Loh YH, Thomas K, Park IH, Garber M, Curran M, Onder T, Agarwal S, Manos PD, Datta S, Lander ES, Schlaeger TM, Daley GQ, Rinn JL.

Nat Genet. 2010 Dec;42(12):1113-7. doi: 10.1038/ng.710. Epub 2010 Nov 7. Erratum in: Nat Genet. 2010 Dec;42(12): 3 p following 1117.

29.

Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

Warren L, Manos PD, Ahfeldt T, Loh YH, Li H, Lau F, Ebina W, Mandal PK, Smith ZD, Meissner A, Daley GQ, Brack AS, Collins JJ, Cowan C, Schlaeger TM, Rossi DJ.

Cell Stem Cell. 2010 Nov 5;7(5):618-30. doi: 10.1016/j.stem.2010.08.012. Epub 2010 Sep 30.

30.

Clump passaging and expansion of human embryonic and induced pluripotent stem cells on mouse embryonic fibroblast feeder cells.

Hartung O, Huo H, Daley GQ, Schlaeger TM.

Curr Protoc Stem Cell Biol. 2010 Aug;Chapter 1:Unit 1C.10. doi: 10.1002/9780470151808.sc01c10s14.

PMID:
20814935
31.

Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage.

Tulpule A, Lensch MW, Miller JD, Austin K, D'Andrea A, Schlaeger TM, Shimamura A, Daley GQ.

Blood. 2010 Apr 29;115(17):3453-62. doi: 10.1182/blood-2009-10-246694. Epub 2010 Jan 20.

32.

Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells.

Chan EM, Ratanasirintrawoot S, Park IH, Manos PD, Loh YH, Huo H, Miller JD, Hartung O, Rho J, Ince TA, Daley GQ, Schlaeger TM.

Nat Biotechnol. 2009 Nov;27(11):1033-7. doi: 10.1038/nbt.1580. Epub 2009 Oct 11.

PMID:
19826408
33.

Improved electrospray ionization efficiency compensates for diminished chromatographic resolution and enables proteomics analysis of tyrosine signaling in embryonic stem cells.

Ficarro SB, Zhang Y, Lu Y, Moghimi AR, Askenazi M, Hyatt E, Smith ED, Boyer L, Schlaeger TM, Luckey CJ, Marto JA.

Anal Chem. 2009 May 1;81(9):3440-7. doi: 10.1021/ac802720e.

PMID:
19331382
34.

Derivation and maintenance of human embryonic stem cells from poor-quality in vitro fertilization embryos.

Lerou PH, Yabuuchi A, Huo H, Miller JD, Boyer LF, Schlaeger TM, Daley GQ.

Nat Protoc. 2008;3(5):923-33. doi: 10.1038/nprot.2008.60.

PMID:
18451800
35.

Teratoma formation assays with human embryonic stem cells: a rationale for one type of human-animal chimera.

Lensch MW, Schlaeger TM, Zon LI, Daley GQ.

Cell Stem Cell. 2007 Sep 13;1(3):253-8. doi: 10.1016/j.stem.2007.07.019. Epub 2007 Aug 23.

36.

Inducible endothelial cell-specific gene expression in transgenic mouse embryos and adult mice.

Deutsch U, Schlaeger TM, Dehouck B, Döring A, Tauber S, Risau W, Engelhardt B.

Exp Cell Res. 2008 Apr 1;314(6):1202-16. doi: 10.1016/j.yexcr.2007.12.026. Epub 2008 Jan 15.

PMID:
18272150
37.

Enhanced plating efficiency of trypsin-adapted human embryonic stem cells is reversible and independent of trisomy 12/17.

Chan EM, Yates F, Boyer LF, Schlaeger TM, Daley GQ.

Cloning Stem Cells. 2008 Mar;10(1):107-18. doi: 10.1089/clo.2007.0064.

PMID:
18241122
38.

Pluripotent stem cells and their niches.

Lensch MW, Daheron L, Schlaeger TM.

Stem Cell Rev. 2006;2(3):185-201. Review.

PMID:
17625255
39.

Science aside: the trajectory of embryonic stem cell research in the USA.

Schlaeger TM, Lensch MW, Taylor PL.

Drug Discov Today. 2007 Apr;12(7-8):269-71. Epub 2007 Mar 1. No abstract available.

PMID:
17395086
40.

Tie2Cre-mediated gene ablation defines the stem-cell leukemia gene (SCL/tal1)-dependent window during hematopoietic stem-cell development.

Schlaeger TM, Mikkola HK, Gekas C, Helgadottir HB, Orkin SH.

Blood. 2005 May 15;105(10):3871-4. Epub 2005 Jan 27.

PMID:
15677556
41.

Decoding hematopoietic specificity in the helix-loop-helix domain of the transcription factor SCL/Tal-1.

Schlaeger TM, Schuh A, Flitter S, Fisher A, Mikkola H, Orkin SH, Vyas P, Porcher C.

Mol Cell Biol. 2004 Sep;24(17):7491-502.

42.

Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene.

Mikkola HK, Klintman J, Yang H, Hock H, Schlaeger TM, Fujiwara Y, Orkin SH.

Nature. 2003 Jan 30;421(6922):547-51. Epub 2003 Jan 19.

PMID:
12540851
43.

Expression of CD41 marks the initiation of definitive hematopoiesis in the mouse embryo.

Mikkola HK, Fujiwara Y, Schlaeger TM, Traver D, Orkin SH.

Blood. 2003 Jan 15;101(2):508-16. Epub 2002 Sep 19.

PMID:
12393529
44.

Endothelium-specific replacement of the connexin43 coding region by a lacZ reporter gene.

Theis M, de Wit C, Schlaeger TM, Eckardt D, Krüger O, Döring B, Risau W, Deutsch U, Pohl U, Willecke K.

Genesis. 2001 Jan;29(1):1-13.

PMID:
11135457
45.

Role of SCL/Tal-1, GATA, and ets transcription factor binding sites for the regulation of flk-1 expression during murine vascular development.

Kappel A, Schlaeger TM, Flamme I, Orkin SH, Risau W, Breier G.

Blood. 2000 Nov 1;96(9):3078-85.

PMID:
11049987
46.

Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice.

Schlaeger TM, Bartunkova S, Lawitts JA, Teichmann G, Risau W, Deutsch U, Sato TN.

Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3058-63.

47.

Vascular endothelial cell lineage-specific promoter in transgenic mice.

Schlaeger TM, Qin Y, Fujiwara Y, Magram J, Sato TN.

Development. 1995 Apr;121(4):1089-98.

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