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Items: 35

1.

Oligodendroglial A-synucleinopathy driven neuroinflammation in multiple system atrophy.

Hoffmann A, Ettle B, Battis K, Reiprich S, Schlachetzki JCM, Masliah E, Wegner M, Kuhlmann T, Riemenschneider MJ, Winkler J.

Brain Pathol. 2018 Nov 16. doi: 10.1111/bpa.12678. [Epub ahead of print]

PMID:
30444295
2.

Microbiome-microglia connections via the gut-brain axis.

Abdel-Haq R, Schlachetzki JCM, Glass CK, Mazmanian SK.

J Exp Med. 2018 Nov 1. pii: jem.20180794. doi: 10.1084/jem.20180794. [Epub ahead of print] Review.

PMID:
30385457
3.

Sensor-based gait analysis of individualized improvement during apomorphine titration in Parkinson's disease.

Marxreiter F, Gaßner H, Borozdina O, Barth J, Kohl Z, Schlachetzki JCM, Thun-Hohenstein C, Volc D, Eskofier BM, Winkler J, Klucken J.

J Neurol. 2018 Nov;265(11):2656-2665. doi: 10.1007/s00415-018-9012-7. Epub 2018 Sep 8.

PMID:
30196324
4.

A monocyte gene expression signature in the early clinical course of Parkinson's disease.

Schlachetzki JCM, Prots I, Tao J, Chun HB, Saijo K, Gosselin D, Winner B, Glass CK, Winkler J.

Sci Rep. 2018 Jul 17;8(1):10757. doi: 10.1038/s41598-018-28986-7.

5.

Mitochondrial Aging Defects Emerge in Directly Reprogrammed Human Neurons due to Their Metabolic Profile.

Kim Y, Zheng X, Ansari Z, Bunnell MC, Herdy JR, Traxler L, Lee H, Paquola ACM, Blithikioti C, Ku M, Schlachetzki JCM, Winkler J, Edenhofer F, Glass CK, Paucar AA, Jaeger BN, Pham S, Boyer L, Campbell BC, Hunter T, Mertens J, Gage FH.

Cell Rep. 2018 May 29;23(9):2550-2558. doi: 10.1016/j.celrep.2018.04.105.

6.

Gait and Cognition in Parkinson's Disease: Cognitive Impairment Is Inadequately Reflected by Gait Performance during Dual Task.

Gaßner H, Marxreiter F, Steib S, Kohl Z, Schlachetzki JCM, Adler W, Eskofier BM, Pfeifer K, Winkler J, Klucken J.

Front Neurol. 2017 Oct 26;8:550. doi: 10.3389/fneur.2017.00550. eCollection 2017.

7.

Wearable sensors objectively measure gait parameters in Parkinson's disease.

Schlachetzki JCM, Barth J, Marxreiter F, Gossler J, Kohl Z, Reinfelder S, Gassner H, Aminian K, Eskofier BM, Winkler J, Klucken J.

PLoS One. 2017 Oct 11;12(10):e0183989. doi: 10.1371/journal.pone.0183989. eCollection 2017.

8.

Increase of Reproductive Life Span Delays Age of Onset of Parkinson's Disease.

Frentzel D, Judanin G, Borozdina O, Klucken J, Winkler J, Schlachetzki JCM.

Front Neurol. 2017 Aug 21;8:397. doi: 10.3389/fneur.2017.00397. eCollection 2017.

9.

An environment-dependent transcriptional network specifies human microglia identity.

Gosselin D, Skola D, Coufal NG, Holtman IR, Schlachetzki JCM, Sajti E, Jaeger BN, O'Connor C, Fitzpatrick C, Pasillas MP, Pena M, Adair A, Gonda DD, Levy ML, Ransohoff RM, Gage FH, Glass CK.

Science. 2017 Jun 23;356(6344). pii: eaal3222. doi: 10.1126/science.aal3222. Epub 2017 May 25.

10.

Distinct Pattern of Microgliosis in the Olfactory Bulb of Neurodegenerative Proteinopathies.

Kohl Z, Schlachetzki JC, Feldewerth J, Hornauer P, Münch M, Adame A, Riemenschneider MJ, Winkler J, Masliah E.

Neural Plast. 2017;2017:3851262. doi: 10.1155/2017/3851262. Epub 2017 Mar 19.

11.

Alpha-synuclein activates BV2 microglia dependent on its aggregation state.

Hoffmann A, Ettle B, Bruno A, Kulinich A, Hoffmann AC, von Wittgenstein J, Winkler J, Xiang W, Schlachetzki JCM.

Biochem Biophys Res Commun. 2016 Oct 28;479(4):881-886. doi: 10.1016/j.bbrc.2016.09.109. Epub 2016 Sep 22.

PMID:
27666480
12.

Paradoxical kinesia in Parkinson's disease revisited: Anticipation of temporal constraints is critical.

Distler M, Schlachetzki JC, Kohl Z, Winkler J, Schenk T.

Neuropsychologia. 2016 Jun;86:38-44. doi: 10.1016/j.neuropsychologia.2016.04.012. Epub 2016 Apr 15.

PMID:
27090103
13.

α-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy.

Ettle B, Kerman BE, Valera E, Gillmann C, Schlachetzki JC, Reiprich S, Büttner C, Ekici AB, Reis A, Wegner M, Bäuerle T, Riemenschneider MJ, Masliah E, Gage FH, Winkler J.

Acta Neuropathol. 2016 Jul;132(1):59-75. doi: 10.1007/s00401-016-1572-y. Epub 2016 Apr 8.

14.

Distinct Effects of Chronic Dopaminergic Stimulation on Hippocampal Neurogenesis and Striatal Doublecortin Expression in Adult Mice.

Salvi R, Steigleder T, Schlachetzki JC, Waldmann E, Schwab S, Winner B, Winkler J, Kohl Z.

Front Neurosci. 2016 Mar 11;10:77. doi: 10.3389/fnins.2016.00077. eCollection 2016.

15.

Dopaminergic lesioning impairs adult hippocampal neurogenesis by distinct modification of α-synuclein.

Schlachetzki JC, Grimm T, Schlachetzki Z, Ben Abdallah NM, Ettle B, Vöhringer P, Ferger B, Winner B, Nuber S, Winkler J.

J Neurosci Res. 2016 Jan;94(1):62-73. doi: 10.1002/jnr.23677. Epub 2015 Oct 9.

PMID:
26451750
16.

The innate immune system in Parkinson's disease: a novel target promoting endogenous neuroregeneration.

Schlachetzki JC, Winkler J.

Neural Regen Res. 2015 May;10(5):704-6. doi: 10.4103/1673-5374.156958. No abstract available.

17.

Hippocampal structure and function are maintained despite severe innate peripheral inflammation.

Süß P, Kalinichenko L, Baum W, Reichel M, Kornhuber J, Loskarn S, Ettle B, Distler JH, Schett G, Winkler J, Müller CP, Schlachetzki JC.

Brain Behav Immun. 2015 Oct;49:156-70. doi: 10.1016/j.bbi.2015.05.011. Epub 2015 Jun 12.

PMID:
26074461
18.

Oligodendroglia and Myelin in Neurodegenerative Diseases: More Than Just Bystanders?

Ettle B, Schlachetzki JCM, Winkler J.

Mol Neurobiol. 2016 Jul;53(5):3046-3062. doi: 10.1007/s12035-015-9205-3. Epub 2015 May 13. Review.

19.

Posttranslational modification and mutation of histidine 50 trigger alpha synuclein aggregation and toxicity.

Xiang W, Menges S, Schlachetzki JC, Meixner H, Hoffmann AC, Schlötzer-Schrehardt U, Becker CM, Winkler J, Klucken J.

Mol Neurodegener. 2015 Mar 11;10:8. doi: 10.1186/s13024-015-0004-0.

20.

Intracellular alpha-synuclein affects early maturation of primary oligodendrocyte progenitor cells.

Ettle B, Reiprich S, Deusser J, Schlachetzki JC, Xiang W, Prots I, Masliah E, Winner B, Wegner M, Winkler J.

Mol Cell Neurosci. 2014 Sep;62:68-78. doi: 10.1016/j.mcn.2014.06.012. Epub 2014 Jul 11.

21.

Frontotemporal dementia and its subtypes: a genome-wide association study.

Ferrari R, Hernandez DG, Nalls MA, Rohrer JD, Ramasamy A, Kwok JB, Dobson-Stone C, Brooks WS, Schofield PR, Halliday GM, Hodges JR, Piguet O, Bartley L, Thompson E, Haan E, Hernández I, Ruiz A, Boada M, Borroni B, Padovani A, Cruchaga C, Cairns NJ, Benussi L, Binetti G, Ghidoni R, Forloni G, Galimberti D, Fenoglio C, Serpente M, Scarpini E, Clarimón J, Lleó A, Blesa R, Waldö ML, Nilsson K, Nilsson C, Mackenzie IR, Hsiung GY, Mann DM, Grafman J, Morris CM, Attems J, Griffiths TD, McKeith IG, Thomas AJ, Pietrini P, Huey ED, Wassermann EM, Baborie A, Jaros E, Tierney MC, Pastor P, Razquin C, Ortega-Cubero S, Alonso E, Perneczky R, Diehl-Schmid J, Alexopoulos P, Kurz A, Rainero I, Rubino E, Pinessi L, Rogaeva E, St George-Hyslop P, Rossi G, Tagliavini F, Giaccone G, Rowe JB, Schlachetzki JC, Uphill J, Collinge J, Mead S, Danek A, Van Deerlin VM, Grossman M, Trojanowski JQ, van der Zee J, Deschamps W, Van Langenhove T, Cruts M, Van Broeckhoven C, Cappa SF, Le Ber I, Hannequin D, Golfier V, Vercelletto M, Brice A, Nacmias B, Sorbi S, Bagnoli S, Piaceri I, Nielsen JE, Hjermind LE, Riemenschneider M, Mayhaus M, Ibach B, Gasparoni G, Pichler S, Gu W, Rossor MN, Fox NC, Warren JD, Spillantini MG, Morris HR, Rizzu P, Heutink P, Snowden JS, Rollinson S, Richardson A, Gerhard A, Bruni AC, Maletta R, Frangipane F, Cupidi C, Bernardi L, Anfossi M, Gallo M, Conidi ME, Smirne N, Rademakers R, Baker M, Dickson DW, Graff-Radford NR, Petersen RC, Knopman D, Josephs KA, Boeve BF, Parisi JE, Seeley WW, Miller BL, Karydas AM, Rosen H, van Swieten JC, Dopper EG, Seelaar H, Pijnenburg YA, Scheltens P, Logroscino G, Capozzo R, Novelli V, Puca AA, Franceschi M, Postiglione A, Milan G, Sorrentino P, Kristiansen M, Chiang HH, Graff C, Pasquier F, Rollin A, Deramecourt V, Lebert F, Kapogiannis D, Ferrucci L, Pickering-Brown S, Singleton AB, Hardy J, Momeni P.

Lancet Neurol. 2014 Jul;13(7):686-99. doi: 10.1016/S1474-4422(14)70065-1.

22.

Granulocyte colony-stimulating factor does not promote neurogenesis after experimental intracerebral haemorrhage.

Kallmünzer B, Tauchi M, Schlachetzki JC, Machold K, Schmidt A, Winkler J, Schwab S, Kollmar R.

Int J Stroke. 2014 Aug;9(6):783-8. doi: 10.1111/ijs.12217. Epub 2013 Dec 19.

PMID:
24920160
23.

Intracerebroventricular administration of nerve growth factor induces gliogenesis in sensory ganglia, dorsal root, and within the dorsal root entry zone.

Schlachetzki JC, Pizzo DP, Morrissette DA, Winkler J.

Biomed Res Int. 2014;2014:704259. doi: 10.1155/2014/704259. Epub 2014 Mar 16.

24.

Increased tyrosine hydroxylase expression accompanied by glial changes within the non-lesioned hemisphere in the 6-hydroxydopamine model of Parkinson's disease.

Schlachetzki JC, Marxreiter F, Regensburger M, Kulinich A, Winner B, Winkler J.

Restor Neurol Neurosci. 2014;32(4):447-62. doi: 10.3233/RNN-130371.

PMID:
24604006
25.

Studying neurodegenerative diseases in culture models.

Schlachetzki JC, Saliba SW, Oliveira AC.

Braz J Psychiatr. 2013;35 Suppl 2:S92-100. doi: 10.1590/1516-4446-2013-1159. Review.

26.

Oxidative stress-induced posttranslational modifications of alpha-synuclein: specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity.

Xiang W, Schlachetzki JC, Helling S, Bussmann JC, Berlinghof M, Schäffer TE, Marcus K, Winkler J, Klucken J, Becker CM.

Mol Cell Neurosci. 2013 May;54:71-83. doi: 10.1016/j.mcn.2013.01.004. Epub 2013 Jan 28.

PMID:
23369945
27.

Pharmacological inhibition of Akt and downstream pathways modulates the expression of COX-2 and mPGES-1 in activated microglia.

de Oliveira AC, Candelario-Jalil E, Langbein J, Wendeburg L, Bhatia HS, Schlachetzki JC, Biber K, Fiebich BL.

J Neuroinflammation. 2012 Jan 3;9:2. doi: 10.1186/1742-2094-9-2.

28.

Norepinephrine enhances the LPS-induced expression of COX-2 and secretion of PGE2 in primary rat microglia.

Schlachetzki JC, Fiebich BL, Haake E, de Oliveira AC, Candelario-Jalil E, Heneka MT, Hüll M.

J Neuroinflammation. 2010 Jan 11;7:2. doi: 10.1186/1742-2094-7-2.

29.

Microglial activation in Alzheimer's disease.

Schlachetzki JC, Hüll M.

Curr Alzheimer Res. 2009 Dec;6(6):554-63. Review.

PMID:
19747160
30.

Frequency of progranulin mutations in a German cohort of 79 frontotemporal dementia patients.

Schlachetzki JC, Schmidtke K, Beckervordersandforth J, Borozdin W, Wilhelm C, Hüll M, Kohlhase J.

J Neurol. 2009 Dec;256(12):2043-51. doi: 10.1007/s00415-009-5248-6. Epub 2009 Jul 19.

PMID:
19618231
31.

Both systemic and local application of granulocyte-colony stimulating factor (G-CSF) is neuroprotective after retinal ganglion cell axotomy.

Frank T, Schlachetzki JC, Göricke B, Meuer K, Rohde G, Dietz GP, Bähr M, Schneider A, Weishaupt JH.

BMC Neurosci. 2009 May 14;10:49. doi: 10.1186/1471-2202-10-49.

32.

Aripiprazole induced hypersexuality in a 24-year-old female patient with schizoaffective disorder?

Schlachetzki JC, Langosch JM.

J Clin Psychopharmacol. 2008 Oct;28(5):567-8. doi: 10.1097/JCP.0b013e31818582de. No abstract available.

PMID:
18794655
33.

Hematopoietic cytokines--on the verge of conquering neurology.

Tönges L, Schlachetzki JC, Weishaupt JH, Bähr M.

Curr Mol Med. 2007 Mar;7(2):157-70. Review.

PMID:
17346168
34.

Granulocyte-colony stimulating factor is neuroprotective in a model of Parkinson's disease.

Meuer K, Pitzer C, Teismann P, Krüger C, Göricke B, Laage R, Lingor P, Peters K, Schlachetzki JC, Kobayashi K, Dietz GP, Weber D, Ferger B, Schäbitz WR, Bach A, Schulz JB, Bähr M, Schneider A, Weishaupt JH.

J Neurochem. 2006 May;97(3):675-86. Epub 2006 Mar 29.

35.

Varicella zoster virus cerebellitis in a 66-year-old patient without herpes zoster.

Ratzka P, Schlachetzki JC, Bähr M, Nau R.

Lancet. 2006 Jan 14;367(9505):182. No abstract available.

PMID:
16413882

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