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An anti-inflammatory phenotype in visceral adipose tissue of old lean mice, augmented by exercise.

Ziegler AK, Damgaard A, Mackey AL, Schjerling P, Magnusson P, Olesen AT, Kjaer M, Scheele C.

Sci Rep. 2019 Aug 19;9(1):12069. doi: 10.1038/s41598-019-48587-2.


Molecular indicators of denervation in aging human skeletal muscle.

Soendenbroe C, Heisterberg MF, Schjerling P, Karlsen A, Kjaer M, Andersen JL, Mackey AL.

Muscle Nerve. 2019 Jul 17. doi: 10.1002/mus.26638. [Epub ahead of print]


Immobilization Decreases FOXO3a Phosphorylation and Increases Autophagy-Related Gene and Protein Expression in Human Skeletal Muscle.

Møller AB, Vendelbo MH, Schjerling P, Couppé C, Møller N, Kjær M, Hansen M, Jessen N.

Front Physiol. 2019 Jun 14;10:736. doi: 10.3389/fphys.2019.00736. eCollection 2019.


Muscle-strain injury exudate favors acute tissue healing and prolonged connective tissue formation in humans.

Bayer ML, Bang L, Hoegberget-Kalisz M, Svensson RB, Olesen JL, Karlsson MM, Schjerling P, Hellsten Y, Hoier B, Magnusson SP, Kjaer M.

FASEB J. 2019 Jun 18:fj201900542R. doi: 10.1096/fj.201900542R. [Epub ahead of print]


Regional differences in turnover, composition, and mechanics of the porcine flexor tendon.

Zhang C, Svensson RB, Couppé C, Schjerling P, Skovgaard D, Kjaer M, Magnusson SP.

Connect Tissue Res. 2019 May 28:1-10. doi: 10.1080/03008207.2019.1620222. [Epub ahead of print]


The influence of direct and indirect fibroblast cell contact on human myogenic cell behavior and gene expression in vitro.

Bechshøft CJL, Schjerling P, Kjaer M, Mackey AL.

J Appl Physiol (1985). 2019 Aug 1;127(2):342-355. doi: 10.1152/japplphysiol.00215.2019. Epub 2019 May 23.


Investigating circadian clock gene expression in human tendon biopsies from acute exercise and immobilization studies.

Yeung CC, Schjerling P, Heinemeier KM, Boesen AP, Dideriksen K, Kjær M.

Eur J Appl Physiol. 2019 Jun;119(6):1387-1394. doi: 10.1007/s00421-019-04129-2. Epub 2019 Mar 28.


Age and prior exercise in vivo determine the subsequent in vitro molecular profile of myoblasts and nonmyogenic cells derived from human skeletal muscle.

Bechshøft CJL, Jensen SM, Schjerling P, Andersen JL, Svensson RB, Eriksen CS, Mkumbuzi NS, Kjaer M, Mackey AL.

Am J Physiol Cell Physiol. 2019 Jun 1;316(6):C898-C912. doi: 10.1152/ajpcell.00049.2019. Epub 2019 Mar 27.


The effect of resistance exercise upon age-related systemic and local skeletal muscle inflammation.

Ziegler AK, Jensen SM, Schjerling P, Mackey AL, Andersen JL, Kjaer M.

Exp Gerontol. 2019 Jul 1;121:19-32. doi: 10.1016/j.exger.2019.03.007. Epub 2019 Mar 21.


Lack of muscle fibre hypertrophy, myonuclear addition, and satellite cell pool expansion with resistance training in 83-94-year-old men and women.

Karlsen A, Bechshøft RL, Malmgaard-Clausen NM, Andersen JL, Schjerling P, Kjaer M, Mackey AL.

Acta Physiol (Oxf). 2019 Sep;227(1):e13271. doi: 10.1111/apha.13271. Epub 2019 Mar 20.


Cellular homeostatic tension and force transmission measured in human engineered tendon.

Giannopoulos A, Svensson RB, Heinemeier KM, Schjerling P, Kadler KE, Holmes DF, Kjaer M, Magnusson SP.

J Biomech. 2018 Sep 10;78:161-165. doi: 10.1016/j.jbiomech.2018.07.032. Epub 2018 Jul 30.


Losartan has no additive effect on the response to heavy-resistance exercise in human elderly skeletal muscle.

Heisterberg MF, Andersen JL, Schjerling P, Lund A, Dalskov S, Jønsson AO, Warming N, Fogelstrøm M, Kjaer M, Mackey AL.

J Appl Physiol (1985). 2018 Nov 1;125(5):1536-1554. doi: 10.1152/japplphysiol.00106.2018. Epub 2018 Aug 9.


Carbon-14 bomb pulse dating shows that tendinopathy is preceded by years of abnormally high collagen turnover.

Heinemeier KM, Schjerling P, Øhlenschlæger TF, Eismark C, Olsen J, Kjær M.

FASEB J. 2018 Sep;32(9):4763-4775. doi: 10.1096/fj.201701569R. Epub 2018 Mar 23.


β-Actin shows limited mobility and is required only for supraphysiological insulin-stimulated glucose transport in young adult soleus muscle.

Madsen AB, Knudsen JR, Henriquez-Olguin C, Angin Y, Zaal KJ, Sylow L, Schjerling P, Ralston E, Jensen TE.

Am J Physiol Endocrinol Metab. 2018 Jul 1;315(1):E110-E125. doi: 10.1152/ajpendo.00392.2017. Epub 2018 Mar 13.


Effect of Losartan on the Acute Response of Human Elderly Skeletal Muscle to Exercise.

Heisterberg MF, Andersen JL, Schjerling P, Bülow J, Lauersen JB, Roeber HL, Kjaer M, Mackey AL.

Med Sci Sports Exerc. 2018 Feb;50(2):225-235. doi: 10.1249/MSS.0000000000001438.


Effect of light-load resistance exercise on postprandial amino acid transporter expression in elderly men.

Agergaard J, Bülow J, Jensen JK, Reitelseder S, Bornø A, Drummond MJ, Schjerling P, Holm L.

Physiol Rep. 2017 Sep;5(18). pii: e13444. doi: 10.14814/phy2.13444. Epub 2017 Sep 27.


Existence of life-time stable proteins in mature rats-Dating of proteins' age by repeated short-term exposure to labeled amino acids throughout age.

Bechshøft CL, Schjerling P, Bornø A, Holm L.

PLoS One. 2017 Sep 28;12(9):e0185605. doi: 10.1371/journal.pone.0185605. eCollection 2017.


Effects of anti-inflammatory (NSAID) treatment on human tendinopathic tissue.

Heinemeier KM, Øhlenschlæger TF, Mikkelsen UR, Sønder F, Schjerling P, Svensson RB, Kjaer M.

J Appl Physiol (1985). 2017 Nov 1;123(5):1397-1405. doi: 10.1152/japplphysiol.00281.2017. Epub 2017 Aug 31.


Gene expression profiling in patients with polymyalgia rheumatica before and after symptom-abolishing glucocorticoid treatment.

Kreiner FF, Borup R, Nielsen FC, Schjerling P, Galbo H.

BMC Musculoskelet Disord. 2017 Aug 7;18(1):341. doi: 10.1186/s12891-017-1705-z.


Skeletal muscle morphology, protein synthesis, and gene expression in Ehlers-Danlos syndrome.

Nygaard RH, Jensen JK, Voermans NC, Heinemeier KM, Schjerling P, Holm L, Agergaard J, Mackey AL, Andersen JL, Remvig L, Kjaer M.

J Appl Physiol (1985). 2017 Aug 1;123(2):482-488. doi: 10.1152/japplphysiol.01044.2016. Epub 2017 Jun 8.


Skeletal muscle morphology and regulatory signalling in endurance-trained and sedentary individuals: The influence of ageing.

Mikkelsen UR, Agergaard J, Couppé C, Grosset JF, Karlsen A, Magnusson SP, Schjerling P, Kjaer M, Mackey AL.

Exp Gerontol. 2017 Jul;93:54-67. doi: 10.1016/j.exger.2017.04.001. Epub 2017 Apr 12.


Rac1 and AMPK Account for the Majority of Muscle Glucose Uptake Stimulated by Ex Vivo Contraction but Not In Vivo Exercise.

Sylow L, Møller LLV, Kleinert M, D'Hulst G, De Groote E, Schjerling P, Steinberg GR, Jensen TE, Richter EA.

Diabetes. 2017 Jun;66(6):1548-1559. doi: 10.2337/db16-1138. Epub 2017 Apr 7.


Impaired collagen synthesis in the rectum may be a molecular target in anastomotic leakage prophylaxis.

Buch AS, Schjerling P, Kjaer M, Jorgensen LN, Krarup PM, Ågren MS.

Wound Repair Regen. 2017 May;25(3):532-535. doi: 10.1111/wrr.12535. Epub 2017 Jun 21.


An advanced glycation endproduct (AGE)-rich diet promotes accumulation of AGEs in Achilles tendon.

Skovgaard D, Svensson RB, Scheijen J, Eliasson P, Mogensen P, Hag AM, Kjær M, Schalkwijk CG, Schjerling P, Magnusson SP, Couppé C.

Physiol Rep. 2017 Mar;5(6). pii: e13215. doi: 10.14814/phy2.13215.


Simvastatin and atorvastatin reduce the mechanical properties of tendon constructs in vitro and introduce catabolic changes in the gene expression pattern.

Eliasson P, Svensson RB, Giannopoulos A, Eismark C, Kjær M, Schjerling P, Heinemeier KM.

PLoS One. 2017 Mar 6;12(3):e0172797. doi: 10.1371/journal.pone.0172797. eCollection 2017.


Tendon collagen synthesis declines with immobilization in elderly humans: no effect of anti-inflammatory medication.

Dideriksen K, Boesen AP, Reitelseder S, Couppé C, Svensson R, Schjerling P, Magnusson SP, Holm L, Kjaer M.

J Appl Physiol (1985). 2017 Feb 1;122(2):273-282. doi: 10.1152/japplphysiol.00809.2015. Epub 2016 Dec 8.


Light-load resistance exercise increases muscle protein synthesis and hypertrophy signaling in elderly men.

Agergaard J, Bülow J, Jensen JK, Reitelseder S, Drummond MJ, Schjerling P, Scheike T, Serena A, Holm L.

Am J Physiol Endocrinol Metab. 2017 Apr 1;312(4):E326-E338. doi: 10.1152/ajpendo.00164.2016. Epub 2016 Oct 25.


mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3.

Kleinert M, Parker BL, Chaudhuri R, Fazakerley DJ, Serup A, Thomas KC, Krycer JR, Sylow L, Fritzen AM, Hoffman NJ, Jeppesen J, Schjerling P, Ruegg MA, Kiens B, James DE, Richter EA.

Mol Metab. 2016 Jun 22;5(8):646-655. doi: 10.1016/j.molmet.2016.06.007. eCollection 2016 Aug.


Quantification of cell density in rat Achilles tendon: development and application of a new method.

Couppé C, Svensson RB, Heinemeier KM, Thomsen EW, Bayer ML, Christensen L, Kjær M, Magnusson SP, Schjerling P.

Histochem Cell Biol. 2017 Jan;147(1):97-102. doi: 10.1007/s00418-016-1482-z. Epub 2016 Aug 26.


Partial Disruption of Lipolysis Increases Postexercise Insulin Sensitivity in Skeletal Muscle Despite Accumulation of DAG.

Serup AK, Alsted TJ, Jordy AB, Schjerling P, Holm C, Kiens B.

Diabetes. 2016 Oct;65(10):2932-42. doi: 10.2337/db16-0655. Epub 2016 Aug 3.


Radiocarbon dating reveals minimal collagen turnover in both healthy and osteoarthritic human cartilage.

Heinemeier KM, Schjerling P, Heinemeier J, Møller MB, Krogsgaard MR, Grum-Schwensen T, Petersen MM, Kjaer M.

Sci Transl Med. 2016 Jul 6;8(346):346ra90. doi: 10.1126/scitranslmed.aad8335.


Acquired Localized Cutis Laxa due to Increased Elastin Turnover.

Nygaard RH, Maynard S, Schjerling P, Kjaer M, Qvortrup K, Bohr VA, Rasmussen LJ, Jemec GB, Heidenheim M.

Case Rep Dermatol. 2016 Feb 13;8(1):42-51. doi: 10.1159/000443696. eCollection 2016 Jan-Apr.


Rac1 in Muscle Is Dispensable for Improved Insulin Action After Exercise in Mice.

Sylow L, Møller LL, D'Hulst G, Schjerling P, Jensen TE, Richter EA.

Endocrinology. 2016 Aug;157(8):3009-15. doi: 10.1210/en.2016-1220. Epub 2016 Jun 10.


Skeletal muscle adaptation to immobilization and subsequent retraining in elderly men: No effect of anti-inflammatory medication.

Dideriksen K, Boesen AP, Kristiansen JF, Magnusson SP, Schjerling P, Holm L, Kjaer M.

Exp Gerontol. 2016 Sep;82:8-18. doi: 10.1016/j.exger.2016.05.009. Epub 2016 May 25.


Muscle satellite cell content and mRNA signaling in germ cell cancer patients - effects of chemotherapy and resistance training.

Christensen JF, Schjerling P, Andersen JL, Daugaard G, Rørth M, Mackey AL.

Acta Oncol. 2016 Sep - Oct;55(9-10):1246-1250. doi: 10.3109/0284186X.2016.1170200. Epub 2016 May 24. No abstract available.


Rac1 governs exercise-stimulated glucose uptake in skeletal muscle through regulation of GLUT4 translocation in mice.

Sylow L, Nielsen IL, Kleinert M, Møller LL, Ploug T, Schjerling P, Bilan PJ, Klip A, Jensen TE, Richter EA.

J Physiol. 2016 Sep 1;594(17):4997-5008. doi: 10.1113/JP272039. Epub 2016 Jun 16.


Role of AMPK in regulation of LC3 lipidation as a marker of autophagy in skeletal muscle.

Fritzen AM, Frøsig C, Jeppesen J, Jensen TE, Lundsgaard AM, Serup AK, Schjerling P, Proud CG, Richter EA, Kiens B.

Cell Signal. 2016 Jun;28(6):663-74. doi: 10.1016/j.cellsig.2016.03.005. Epub 2016 Mar 12.


Collagen content in the vastus lateralis and the soleus muscle following a 90-day bed rest period with or without resistance exercises.

Nielsen RO, Schjerling P, Tesch P, Stål P, Langberg H.

Muscles Ligaments Tendons J. 2016 Feb 13;5(4):305-9. doi: 10.11138/mltj/2015.5.4.305. eCollection 2015 Oct-Dec.


Activation of satellite cells and the regeneration of human skeletal muscle are expedited by ingestion of nonsteroidal anti-inflammatory medication.

Mackey AL, Rasmussen LK, Kadi F, Schjerling P, Helmark IC, Ponsot E, Aagaard P, Durigan JL, Kjaer M.

FASEB J. 2016 Jun;30(6):2266-81. doi: 10.1096/fj.201500198R. Epub 2016 Mar 2.


Local trauma in human patellar tendon leads to widespread changes in the tendon gene expression.

Heinemeier KM, Lorentzen MP, Jensen JK, Schjerling P, Seynnes OR, Narici MV, Kjaer M.

J Appl Physiol (1985). 2016 May 1;120(9):1000-10. doi: 10.1152/japplphysiol.00870.2015. Epub 2016 Jan 14.


Satellite cell response to erythropoietin treatment and endurance training in healthy young men.

Hoedt A, Christensen B, Nellemann B, Mikkelsen UR, Hansen M, Schjerling P, Farup J.

J Physiol. 2016 Feb 1;594(3):727-43. doi: 10.1113/JP271333. Epub 2015 Dec 30.


Does vitamin-D intake during resistance training improve the skeletal muscle hypertrophic and strength response in young and elderly men? - a randomized controlled trial.

Agergaard J, Trøstrup J, Uth J, Iversen JV, Boesen A, Andersen JL, Schjerling P, Langberg H.

Nutr Metab (Lond). 2015 Sep 30;12:32. doi: 10.1186/s12986-015-0029-y. eCollection 2015.


AMPKα is essential for acute exercise-induced gene responses but not for exercise training-induced adaptations in mouse skeletal muscle.

Fentz J, Kjøbsted R, Kristensen CM, Hingst JR, Birk JB, Gudiksen A, Foretz M, Schjerling P, Viollet B, Pilegaard H, Wojtaszewski JF.

Am J Physiol Endocrinol Metab. 2015 Dec 1;309(11):E900-14. doi: 10.1152/ajpendo.00157.2015. Epub 2015 Sep 29.


Preserved skeletal muscle protein anabolic response to acute exercise and protein intake in well-treated rheumatoid arthritis patients.

Mikkelsen UR, Dideriksen K, Andersen MB, Boesen A, Malmgaard-Clausen NM, Sørensen IJ, Schjerling P, Kjær M, Holm L.

Arthritis Res Ther. 2015 Sep 25;17:271. doi: 10.1186/s13075-015-0758-3.


Leukemia inhibitory factor increases glucose uptake in mouse skeletal muscle.

Brandt N, O'Neill HM, Kleinert M, Schjerling P, Vernet E, Steinberg GR, Richter EA, Jørgensen SB.

Am J Physiol Endocrinol Metab. 2015 Jul 15;309(2):E142-53. doi: 10.1152/ajpendo.00313.2014. Epub 2015 May 12.


AMPKα is critical for enhancing skeletal muscle fatty acid utilization during in vivo exercise in mice.

Fentz J, Kjøbsted R, Birk JB, Jordy AB, Jeppesen J, Thorsen K, Schjerling P, Kiens B, Jessen N, Viollet B, Wojtaszewski JF.

FASEB J. 2015 May;29(5):1725-38. doi: 10.1096/fj.14-266650. Epub 2015 Jan 21.


Prior AICAR stimulation increases insulin sensitivity in mouse skeletal muscle in an AMPK-dependent manner.

Kjøbsted R, Treebak JT, Fentz J, Lantier L, Viollet B, Birk JB, Schjerling P, Björnholm M, Zierath JR, Wojtaszewski JF.

Diabetes. 2015 Jun;64(6):2042-55. doi: 10.2337/db14-1402. Epub 2014 Dec 31.


The activity of satellite cells and myonuclei following 8 weeks of strength training in young men with suppressed testosterone levels.

Kvorning T, Kadi F, Schjerling P, Andersen M, Brixen K, Suetta C, Madsen K.

Acta Physiol (Oxf). 2015 Mar;213(3):676-87. doi: 10.1111/apha.12404. Epub 2014 Nov 15.


Serum insulin-like growth factor 1 in the aging horse.

Lygren T, Hansen S, Langberg H, Fjeldborg J, Jacobsen S, Nielsen MO, Schjerling P, Markussen B, Thomsen PD, Berg LC.

Vet Clin Pathol. 2014 Dec;43(4):557-60. doi: 10.1111/vcp.12201. Epub 2014 Sep 22.


Vitamin D-binding protein controls T cell responses to vitamin D.

Kongsbak M, von Essen MR, Levring TB, Schjerling P, Woetmann A, Ødum N, Bonefeld CM, Geisler C.

BMC Immunol. 2014 Sep 18;15:35. doi: 10.1186/s12865-014-0035-2.

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