Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 98

1.

Staphylococcus aureus Lpl protein triggers human host cell invasion via activation of Hsp90 receptor.

Tribelli PM, Luqman A, Nguyen MT, Madlung J, Fan SH, Macek B, Sass P, Bitschar K, Schittek B, Kretschmer D, Götz F.

Cell Microbiol. 2019 Sep 13:e13111. doi: 10.1111/cmi.13111. [Epub ahead of print]

PMID:
31515903
2.

Lugdunin amplifies innate immune responses in the skin in synergy with host- and microbiota-derived factors.

Bitschar K, Sauer B, Focken J, Dehmer H, Moos S, Konnerth M, Schilling NA, Grond S, Kalbacher H, Kurschus FC, Götz F, Krismer B, Peschel A, Schittek B.

Nat Commun. 2019 Jun 21;10(1):2730. doi: 10.1038/s41467-019-10646-7.

3.

Quantitative Proteomics Links the Intermediate Filament Nestin to Resistance to Targeted BRAF Inhibition in Melanoma Cells.

Schmitt M, Sinnberg T, Nalpas NC, Maass A, Schittek B, Macek B.

Mol Cell Proteomics. 2019 Jun;18(6):1096-1109. doi: 10.1074/mcp.RA119.001302. Epub 2019 Mar 19.

PMID:
30890564
4.

Melanoma cells resistant towards MAPK inhibitors exhibit reduced TAp73 expression mediating enhanced sensitivity to platinum-based drugs.

Makino E, Gutmann V, Kosnopfel C, Niessner H, Forschner A, Garbe C, Sinnberg T, Schittek B.

Cell Death Dis. 2018 Sep 11;9(9):930. doi: 10.1038/s41419-018-0952-8.

5.

YB-1 Expression and Phosphorylation Regulate Tumorigenicity and Invasiveness in Melanoma by Influencing EMT.

Kosnopfel C, Sinnberg T, Sauer B, Busch C, Niessner H, Schmitt A, Forchhammer S, Grimmel C, Mertens PR, Hailfinger S, Dunn SE, Garbe C, Schittek B.

Mol Cancer Res. 2018 Jul;16(7):1149-1160. doi: 10.1158/1541-7786.MCR-17-0528. Epub 2018 May 9.

6.

Staphylococcal (phospho)lipases promote biofilm formation and host cell invasion.

Nguyen MT, Luqman A, Bitschar K, Hertlein T, Dick J, Ohlsen K, Bröker B, Schittek B, Götz F.

Int J Med Microbiol. 2018 Aug;308(6):653-663. doi: 10.1016/j.ijmm.2017.11.013. Epub 2017 Nov 29.

PMID:
29203111
7.

Correction for Ebner et al., "Excreted Cytoplasmic Proteins Contribute to Pathogenicity in Staphylococcus aureus".

Ebner P, Rinker J, Nguyen MT, Popella P, Nega M, Luqman A, Schittek B, Di Marco M, Stevanovic S, Götz F.

Infect Immun. 2017 Nov 17;85(12). pii: e00641-17. doi: 10.1128/IAI.00641-17. Print 2017 Dec. No abstract available.

8.

Entry, Intracellular Survival, and Multinucleated-Giant-Cell-Forming Activity of Burkholderia pseudomallei in Human Primary Phagocytic and Nonphagocytic Cells.

Whiteley L, Meffert T, Haug M, Weidenmaier C, Hopf V, Bitschar K, Schittek B, Kohler C, Steinmetz I, West TE, Schwarz S.

Infect Immun. 2017 Sep 20;85(10). pii: e00468-17. doi: 10.1128/IAI.00468-17. Print 2017 Oct.

9.

Anthralin modulates the expression pattern of cytokeratins and antimicrobial peptides by psoriatic keratinocytes.

Holstein J, Fehrenbacher B, Brück J, Müller-Hermelink E, Schäfer I, Carevic M, Schittek B, Schaller M, Ghoreschi K, Eberle FC.

J Dermatol Sci. 2017 Sep;87(3):236-245. doi: 10.1016/j.jdermsci.2017.06.007. Epub 2017 Jun 15.

PMID:
28673488
10.

Keratinocytes as sensors and central players in the immune defense against Staphylococcus aureus in the skin.

Bitschar K, Wolz C, Krismer B, Peschel A, Schittek B.

J Dermatol Sci. 2017 Sep;87(3):215-220. doi: 10.1016/j.jdermsci.2017.06.003. Epub 2017 Jun 10. Review.

PMID:
28655473
11.

Human melanoma cells resistant to MAPK inhibitors can be effectively targeted by inhibition of the p90 ribosomal S6 kinase.

Kosnopfel C, Sinnberg T, Sauer B, Niessner H, Schmitt A, Makino E, Forschner A, Hailfinger S, Garbe C, Schittek B.

Oncotarget. 2017 May 30;8(22):35761-35775. doi: 10.18632/oncotarget.16204.

12.

The Protective Effect of Microbiota on S. aureus Skin Colonization Depends on the Integrity of the Epithelial Barrier.

Burian M, Bitschar K, Dylus B, Peschel A, Schittek B.

J Invest Dermatol. 2017 Apr;137(4):976-979. doi: 10.1016/j.jid.2016.11.024. Epub 2016 Dec 3. No abstract available.

13.

Corrigendum: Human commensals producing a novel antibiotic impair pathogen colonization.

Zipperer A, Konnerth MC, Laux C, Berscheid A, Janek D, Weidenmaier C, Burian M, Schilling NA, Slavetinsky C, Marschal M, Willmann M, Kalbacher H, Schittek B, Brötz-Oesterhelt H, Grond S, Peschel A, Krismer B.

Nature. 2016 Nov 10;539(7628):314. doi: 10.1038/nature19781. Epub 2016 Sep 14. No abstract available.

PMID:
27626388
14.

PI3K Pathway Inhibition Achieves Potent Antitumor Activity in Melanoma Brain Metastases In Vitro and In Vivo.

Niessner H, Schmitz J, Tabatabai G, Schmid AM, Calaminus C, Sinnberg T, Weide B, Eigentler TK, Garbe C, Schittek B, Quintanilla-Fend L, Bender B, Mai M, Praetorius C, Beissert S, Schackert G, Muders MH, Meinhardt M, Baretton GB, Dummer R, Flaherty K, Pichler BJ, Kulms D, Westphal D, Meier F.

Clin Cancer Res. 2016 Dec 1;22(23):5818-5828. Epub 2016 Jun 15. Erratum in: Clin Cancer Res. 2017 Mar 1;23 (5):1361.

15.

Casein kinase 1α has a non-redundant and dominant role within the CK1 family in melanoma progression.

Sinnberg T, Wang J, Sauer B, Schittek B.

BMC Cancer. 2016 Aug 3;16:594. doi: 10.1186/s12885-016-2643-0.

16.

Human commensals producing a novel antibiotic impair pathogen colonization.

Zipperer A, Konnerth MC, Laux C, Berscheid A, Janek D, Weidenmaier C, Burian M, Schilling NA, Slavetinsky C, Marschal M, Willmann M, Kalbacher H, Schittek B, Brötz-Oesterhelt H, Grond S, Peschel A, Krismer B.

Nature. 2016 Jul 28;535(7613):511-6. doi: 10.1038/nature18634. Erratum in: Nature. 2016 Nov 10;539(7628):314.

PMID:
27466123
17.

A Nexus Consisting of Beta-Catenin and Stat3 Attenuates BRAF Inhibitor Efficacy and Mediates Acquired Resistance to Vemurafenib.

Sinnberg T, Makino E, Krueger MA, Velic A, Macek B, Rothbauer U, Groll N, Pötz O, Czemmel S, Niessner H, Meier F, Ikenberg K, Garbe C, Schittek B.

EBioMedicine. 2016 Jun;8:132-149. doi: 10.1016/j.ebiom.2016.04.037. Epub 2016 May 1.

18.

UVA-Irradiation Induces Melanoma Invasion via the Enhanced Warburg Effect.

Kamenisch Y, Baban TSA, Schuller W, von Thaler AK, Sinnberg T, Metzler G, Bauer J, Schittek B, Garbe C, Rocken M, Berneburg M.

J Invest Dermatol. 2016 Sep;136(9):1866-1875. doi: 10.1016/j.jid.2016.02.815. Epub 2016 May 13. Review.

19.

Excreted Cytoplasmic Proteins Contribute to Pathogenicity in Staphylococcus aureus.

Ebner P, Rinker J, Nguyen MT, Popella P, Nega M, Luqman A, Schittek B, Di Marco M, Stevanovic S, Götz F.

Infect Immun. 2016 May 24;84(6):1672-81. doi: 10.1128/IAI.00138-16. Print 2016 Jun. Erratum in: Infect Immun. 2017 Nov 17;85(12 ):.

20.

Sildenafil Potentiates a cGMP-Dependent Pathway to Promote Melanoma Growth.

Dhayade S, Kaesler S, Sinnberg T, Dobrowinski H, Peters S, Naumann U, Liu H, Hunger RE, Thunemann M, Biedermann T, Schittek B, Simon HU, Feil S, Feil R.

Cell Rep. 2016 Mar 22;14(11):2599-610. doi: 10.1016/j.celrep.2016.02.028. Epub 2016 Mar 10.

21.

MALT1 Protease Activity Controls the Expression of Inflammatory Genes in Keratinocytes upon Zymosan Stimulation.

Schmitt A, Grondona P, Maier T, Brändle M, Schönfeld C, Jäger G, Kosnopfel C, Eberle FC, Schittek B, Schulze-Osthoff K, Yazdi AS, Hailfinger S.

J Invest Dermatol. 2016 Apr;136(4):788-797. doi: 10.1016/j.jid.2015.12.027. Epub 2016 Jan 6.

22.

Correction: The νSaα Specific Lipoprotein Like Cluster (lpl) of S. aureus USA300 Contributes to Immune Stimulation and Invasion in Human Cells.

Nguyen MT, Kraft B, Yu W, Demircioglu DD, Hertlein T, Burian M, Schmaler M, Boller K, Bekeredjian-Ding I, Ohlsen K, Schittek B, Götz F.

PLoS Pathog. 2015 Sep 25;11(9):e1005189. doi: 10.1371/journal.ppat.1005189. eCollection 2015 Sep. No abstract available.

23.

PTEN regulates IGF-1R-mediated therapy resistance in melanoma.

Wang J, Sinnberg T, Niessner H, Dölker R, Sauer B, Kempf WE, Meier F, Leslie N, Schittek B.

Pigment Cell Melanoma Res. 2015 Sep;28(5):572-89. doi: 10.1111/pcmr.12390.

PMID:
26112748
24.

The νSaα Specific Lipoprotein Like Cluster (lpl) of S. aureus USA300 Contributes to Immune Stimulation and Invasion in Human Cells.

Nguyen MT, Kraft B, Yu W, Demircioglu DD, Hertlein T, Burian M, Schmaler M, Boller K, Bekeredjian-Ding I, Ohlsen K, Schittek B, Götz F.

PLoS Pathog. 2015 Jun 17;11(6):e1004984. doi: 10.1371/journal.ppat.1004984. eCollection 2015 Jun. Erratum in: PLoS Pathog. 2015 Sep;11(9):e1005189. Demicrioglu, Dogan Doruk [corrected to Demircioglu, Dogan Doruk].

25.

The secrets of dermcidin action.

Burian M, Schittek B.

Int J Med Microbiol. 2015 Feb;305(2):283-6. doi: 10.1016/j.ijmm.2014.12.012. Epub 2014 Dec 24. Review.

PMID:
25596890
26.

Quantitative proteomics of the human skin secretome reveal a reduction in immune defense mediators in ectodermal dysplasia patients.

Burian M, Velic A, Matic K, Günther S, Kraft B, Gonser L, Forchhammer S, Tiffert Y, Naumer C, Krohn M, Berneburg M, Yazdi AS, Maček B, Schittek B.

J Invest Dermatol. 2015 Mar;135(3):759-767. doi: 10.1038/jid.2014.462. Epub 2014 Oct 27.

27.

Biological functions of casein kinase 1 isoforms and putative roles in tumorigenesis.

Schittek B, Sinnberg T.

Mol Cancer. 2014 Oct 11;13:231. doi: 10.1186/1476-4598-13-231. Review.

28.

Y-box binding protein 1--a prognostic marker and target in tumour therapy.

Kosnopfel C, Sinnberg T, Schittek B.

Eur J Cell Biol. 2014 Jan-Feb;93(1-2):61-70. doi: 10.1016/j.ejcb.2013.11.007. Epub 2013 Dec 27. Review.

PMID:
24461929
29.

Processing of laminin α chains generates peptides involved in wound healing and host defense.

Senyürek I, Kempf WE, Klein G, Maurer A, Kalbacher H, Schäfer L, Wanke I, Christ C, Stevanovic S, Schaller M, Rousselle P, Garbe C, Biedermann T, Schittek B.

J Innate Immun. 2014;6(4):467-84. doi: 10.1159/000357032. Epub 2014 Jan 18.

30.

YBX1 is a modulator of MIA/CD-RAP-dependent chondrogenesis.

Schmid R, Meyer K, Spang R, Schittek B, Bosserhoff AK.

PLoS One. 2013 Dec 12;8(12):e82166. doi: 10.1371/journal.pone.0082166. eCollection 2013.

31.

Melanoma inhibitory activity promotes melanoma development through activation of YBX1.

Schmid R, Meyer K, Spang R, Schittek B, Bosserhoff AK.

Pigment Cell Melanoma Res. 2013 Sep;26(5):685-96. doi: 10.1111/pcmr.12119. Epub 2013 Jun 14.

PMID:
23672612
32.

Staphylococcus aureus skin colonization is promoted by barrier disruption and leads to local inflammation.

Wanke I, Skabytska Y, Kraft B, Peschel A, Biedermann T, Schittek B.

Exp Dermatol. 2013 Feb;22(2):153-5. doi: 10.1111/exd.12083.

PMID:
23362876
33.

Vemurafenib potently induces endoplasmic reticulum stress-mediated apoptosis in BRAFV600E melanoma cells.

Beck D, Niessner H, Smalley KS, Flaherty K, Paraiso KH, Busch C, Sinnberg T, Vasseur S, Iovanna JL, Drießen S, Stork B, Wesselborg S, Schaller M, Biedermann T, Bauer J, Lasithiotakis K, Weide B, Eberle J, Schittek B, Schadendorf D, Garbe C, Kulms D, Meier F.

Sci Signal. 2013 Jan 29;6(260):ra7. doi: 10.1126/scisignal.2003057.

34.

miR-137 inhibits the invasion of melanoma cells through downregulation of multiple oncogenic target genes.

Luo C, Tetteh PW, Merz PR, Dickes E, Abukiwan A, Hotz-Wagenblatt A, Holland-Cunz S, Sinnberg T, Schittek B, Schadendorf D, Diederichs S, Eichmüller SB.

J Invest Dermatol. 2013 Mar;133(3):768-775. doi: 10.1038/jid.2012.357. Epub 2012 Nov 15.

35.

The multiple facets of dermcidin in cell survival and host defense.

Schittek B.

J Innate Immun. 2012;4(4):349-60. doi: 10.1159/000336844. Epub 2012 Mar 27. Review.

36.

MAPK and PI3K/AKT mediated YB-1 activation promotes melanoma cell proliferation which is counteracted by an autoregulatory loop.

Sinnberg T, Sauer B, Holm P, Spangler B, Kuphal S, Bosserhoff A, Schittek B.

Exp Dermatol. 2012 Apr;21(4):265-70. doi: 10.1111/j.1600-0625.2012.01448.x.

PMID:
22417301
37.

Structure-activity analysis of the dermcidin-derived peptide DCD-1L, an anionic antimicrobial peptide present in human sweat.

Paulmann M, Arnold T, Linke D, Özdirekcan S, Kopp A, Gutsmann T, Kalbacher H, Wanke I, Schuenemann VJ, Habeck M, Bürck J, Ulrich AS, Schittek B.

J Biol Chem. 2012 Mar 9;287(11):8434-43. doi: 10.1074/jbc.M111.332270. Epub 2012 Jan 18.

38.

β-Catenin signaling increases during melanoma progression and promotes tumor cell survival and chemoresistance.

Sinnberg T, Menzel M, Ewerth D, Sauer B, Schwarz M, Schaller M, Garbe C, Schittek B.

PLoS One. 2011;6(8):e23429. doi: 10.1371/journal.pone.0023429. Epub 2011 Aug 17.

39.

ETS-1/RhoC signaling regulates the transcription factor c-Jun in melanoma.

Spangler B, Kappelmann M, Schittek B, Meierjohann S, Vardimon L, Bosserhoff AK, Kuphal S.

Int J Cancer. 2012 Jun 15;130(12):2801-11. doi: 10.1002/ijc.26277. Epub 2011 Aug 12.

40.

The antimicrobial skin barrier in patients with atopic dermatitis.

Schittek B.

Curr Probl Dermatol. 2011;41:54-67. doi: 10.1159/000323296. Epub 2011 May 12. Review.

PMID:
21576947
41.

Impact of oncogenic K-RAS on YB-1 phosphorylation induced by ionizing radiation.

Toulany M, Schickfluss TA, Eicheler W, Kehlbach R, Schittek B, Rodemann HP.

Breast Cancer Res. 2011 Mar 10;13(2):R28. doi: 10.1186/bcr2845.

42.

Skin commensals amplify the innate immune response to pathogens by activation of distinct signaling pathways.

Wanke I, Steffen H, Christ C, Krismer B, Götz F, Peschel A, Schaller M, Schittek B.

J Invest Dermatol. 2011 Feb;131(2):382-90. doi: 10.1038/jid.2010.328. Epub 2010 Nov 4.

43.

The farnesyl transferase inhibitor lonafarnib inhibits mTOR signaling and enforces sorafenib-induced apoptosis in melanoma cells.

Niessner H, Beck D, Sinnberg T, Lasithiotakis K, Maczey E, Gogel J, Venturelli S, Berger A, Mauthe M, Toulany M, Flaherty K, Schaller M, Schadendorf D, Proikas-Cezanne T, Schittek B, Garbe C, Kulms D, Meier F.

J Invest Dermatol. 2011 Feb;131(2):468-79. doi: 10.1038/jid.2010.297. Epub 2010 Oct 14.

44.

Suppression of casein kinase 1alpha in melanoma cells induces a switch in beta-catenin signaling to promote metastasis.

Sinnberg T, Menzel M, Kaesler S, Biedermann T, Sauer B, Nahnsen S, Schwarz M, Garbe C, Schittek B.

Cancer Res. 2010 Sep 1;70(17):6999-7009. doi: 10.1158/0008-5472.CAN-10-0645. Epub 2010 Aug 10.

45.

Peptides derived from the human laminin alpha4 and alpha5 chains exhibit antimicrobial activity.

Senyürek I, Klein G, Kalbacher H, Deeg M, Schittek B.

Peptides. 2010 Aug;31(8):1468-72. doi: 10.1016/j.peptides.2010.04.016. Epub 2010 Apr 28.

PMID:
20433883
46.

Severity of Staphylococcus aureus infection of the skin is associated with inducibility of human beta-defensin 3 but not human beta-defensin 2.

Zanger P, Holzer J, Schleucher R, Scherbaum H, Schittek B, Gabrysch S.

Infect Immun. 2010 Jul;78(7):3112-7. doi: 10.1128/IAI.00078-10. Epub 2010 Apr 19.

47.

Interaction of C-type lectin-like receptors NKp65 and KACL facilitates dedicated immune recognition of human keratinocytes.

Spreu J, Kuttruff S, Stejfova V, Dennehy KM, Schittek B, Steinle A.

Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5100-5. doi: 10.1073/pnas.0913108107. Epub 2010 Mar 1.

48.

Multicentre study on standardisation of melanoma cell culture--an initiative of the German Melanoma Research Network.

Eberle J, Spangler B, Becker JC, Heinemann SH, Klein CA, Kunz M, Kuphal S, Langer P, Mauch C, Meierjohann S, Paschen A, Schadendorf D, Schartl M, Schittek B, Schönherr R, Tüting T, Zigrino P, Bosserhoff AK; German Melanoma Research Network of the German Cancer Aid.

Pigment Cell Melanoma Res. 2010 Apr;23(2):296-8. doi: 10.1111/j.1755-148X.2010.00684.x. Epub 2010 Feb 5. No abstract available.

PMID:
20137059
49.

Constitutive expression of the antimicrobial peptide RNase 7 is associated with Staphylococcus aureus infection of the skin.

Zanger P, Holzer J, Schleucher R, Steffen H, Schittek B, Gabrysch S.

J Infect Dis. 2009 Dec 15;200(12):1907-15. doi: 10.1086/648408.

PMID:
19919305
50.

Staphylococcus aureus mutant screen reveals interaction of the human antimicrobial peptide dermcidin with membrane phospholipids.

Li M, Rigby K, Lai Y, Nair V, Peschel A, Schittek B, Otto M.

Antimicrob Agents Chemother. 2009 Oct;53(10):4200-10. doi: 10.1128/AAC.00428-09. Epub 2009 Jul 13.

Supplemental Content

Loading ...
Support Center