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Items: 1 to 50 of 113

1.

Calculating the homology and intersection form of a 4-manifold from a trisection diagram.

Feller P, Klug M, Schirmer T, Zemke D.

Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):10869-10874. doi: 10.1073/pnas.1717176115.

2.

Cyclic di-GMP differentially tunes a bacterial flagellar motor through a novel class of CheY-like regulators.

Nesper J, Hug I, Kato S, Hee CS, Habazettl JM, Manfredi P, Grzesiek S, Schirmer T, Emonet T, Jenal U.

Elife. 2017 Nov 1;6. pii: e28842. doi: 10.7554/eLife.28842.

3.

The BID Domain of Type IV Secretion Substrates Forms a Conserved Four-Helix Bundle Topped with a Hook.

Stanger FV, de Beer TAP, Dranow DM, Schirmer T, Phan I, Dehio C.

Structure. 2017 Jan 3;25(1):203-211. doi: 10.1016/j.str.2016.10.010. Epub 2016 Nov 23.

4.

Crystal Structure of the Escherichia coli Fic Toxin-Like Protein in Complex with Its Cognate Antitoxin.

Stanger FV, Harms A, Dehio C, Schirmer T.

PLoS One. 2016 Sep 22;11(9):e0163654. doi: 10.1371/journal.pone.0163654. eCollection 2016.

5.

Cyclic di-GMP mediates a histidine kinase/phosphatase switch by noncovalent domain cross-linking.

Dubey BN, Lori C, Ozaki S, Fucile G, Plaza-Menacho I, Jenal U, Schirmer T.

Sci Adv. 2016 Sep 16;2(9):e1600823. doi: 10.1126/sciadv.1600823. eCollection 2016 Sep.

6.

C-di-GMP Synthesis: Structural Aspects of Evolution, Catalysis and Regulation.

Schirmer T.

J Mol Biol. 2016 Sep 25;428(19):3683-701. doi: 10.1016/j.jmb.2016.07.023. Epub 2016 Aug 4. Review.

7.

Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification.

Stanger FV, Burmann BM, Harms A, Aragão H, Mazur A, Sharpe T, Dehio C, Hiller S, Schirmer T.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):E529-37. doi: 10.1073/pnas.1516930113. Epub 2016 Jan 19.

8.

Expression and Genetic Activation of Cyclic Di-GMP-Specific Phosphodiesterases in Escherichia coli.

Reinders A, Hee CS, Ozaki S, Mazur A, Boehm A, Schirmer T, Jenal U.

J Bacteriol. 2015 Nov 9;198(3):448-62. doi: 10.1128/JB.00604-15. Print 2016 Feb 1.

9.

Adenylylation of Gyrase and Topo IV by FicT Toxins Disrupts Bacterial DNA Topology.

Harms A, Stanger FV, Scheu PD, de Jong IG, Goepfert A, Glatter T, Gerdes K, Schirmer T, Dehio C.

Cell Rep. 2015 Sep 1;12(9):1497-507. doi: 10.1016/j.celrep.2015.07.056. Epub 2015 Aug 20.

10.

Cyclic di-GMP acts as a cell cycle oscillator to drive chromosome replication.

Lori C, Ozaki S, Steiner S, Böhm R, Abel S, Dubey BN, Schirmer T, Hiller S, Jenal U.

Nature. 2015 Jul 9;523(7559):236-9. doi: 10.1038/nature14473. Epub 2015 May 6.

PMID:
25945741
11.

Directed divergent evolution of a thermostable D-tagatose epimerase towards improved activity for two hexose substrates.

Bosshart A, Hee CS, Bechtold M, Schirmer T, Panke S.

Chembiochem. 2015 Mar 2;16(4):592-601. doi: 10.1002/cbic.201402620. Epub 2015 Feb 5.

PMID:
25655925
12.

Structural, kinetic, and docking studies of artificial imine reductases based on biotin-streptavidin technology: an induced lock-and-key hypothesis.

Robles VM, Dürrenberger M, Heinisch T, Lledós A, Schirmer T, Ward TR, Maréchal JD.

J Am Chem Soc. 2014 Nov 5;136(44):15676-83. doi: 10.1021/ja508258t. Epub 2014 Oct 28.

PMID:
25317660
13.

Effects of inner volume field-of-view reduction on myocardial T2 mapping.

Gibiino F, Lechner-Greite S, Schirmer T, Positano V, Brau A, Stainsby JA, Slavin GS, Landini L, Janich MA.

J Magn Reson Imaging. 2015 Jul;42(1):175-9. doi: 10.1002/jmri.24763. Epub 2014 Sep 25.

PMID:
25256847
14.

Structure of the N-terminal Gyrase B fragment in complex with ADP⋅Pi reveals rigid-body motion induced by ATP hydrolysis.

Stanger FV, Dehio C, Schirmer T.

PLoS One. 2014 Sep 9;9(9):e107289. doi: 10.1371/journal.pone.0107289. eCollection 2014.

15.

Activation and polar sequestration of PopA, a c-di-GMP effector protein involved in Caulobacter crescentus cell cycle control.

Ozaki S, Schalch-Moser A, Zumthor L, Manfredi P, Ebbensgaard A, Schirmer T, Jenal U.

Mol Microbiol. 2014 Nov;94(3):580-94. doi: 10.1111/mmi.12777. Epub 2014 Sep 22.

16.

Structure of the oligogalacturonate-specific KdgM porin.

Hutter CA, Lehner R, Wirth Ch, Condemine G, Peneff C, Schirmer T.

Acta Crystallogr D Biol Crystallogr. 2014 Jun;70(Pt 6):1770-8. doi: 10.1107/S1399004714007147. Epub 2014 May 30.

PMID:
24914987
17.

Inherent regulation of EAL domain-catalyzed hydrolysis of second messenger cyclic di-GMP.

Sundriyal A, Massa C, Samoray D, Zehender F, Sharpe T, Jenal U, Schirmer T.

J Biol Chem. 2014 Mar 7;289(10):6978-90. doi: 10.1074/jbc.M113.516195. Epub 2014 Jan 22.

18.

Structure and signaling mechanism of a zinc-sensory diguanylate cyclase.

Zähringer F, Lacanna E, Jenal U, Schirmer T, Boehm A.

Structure. 2013 Jul 2;21(7):1149-57. doi: 10.1016/j.str.2013.04.026. Epub 2013 Jun 13.

19.

Conserved inhibitory mechanism and competent ATP binding mode for adenylyltransferases with Fic fold.

Goepfert A, Stanger FV, Dehio C, Schirmer T.

PLoS One. 2013 May 30;8(5):e64901. doi: 10.1371/journal.pone.0064901. Print 2013.

20.

A dual anchoring strategy for the localization and activation of artificial metalloenzymes based on the biotin-streptavidin technology.

Zimbron JM, Heinisch T, Schmid M, Hamels D, Nogueira ES, Schirmer T, Ward TR.

J Am Chem Soc. 2013 Apr 10;135(14):5384-8. doi: 10.1021/ja309974s. Epub 2013 Apr 2.

PMID:
23496309
21.

Quantification of muscle fat in patients with low back pain: comparison of multi-echo MR imaging with single-voxel MR spectroscopy.

Fischer MA, Nanz D, Shimakawa A, Schirmer T, Guggenberger R, Chhabra A, Carrino JA, Andreisek G.

Radiology. 2013 Feb;266(2):555-63. doi: 10.1148/radiol.12120399. Epub 2012 Nov 9.

PMID:
23143025
22.

SU-E-I-65: Magnetic Resonance Spectroscopy of the Prostate: A Phantom Study of Metabolite Concentrations.

Hossain M, Richardson T, Buyyounouski MK, Schirmer T, Noeske R, Chen L, Ma C.

Med Phys. 2012 Jun;39(6Part5):3639-3640. doi: 10.1118/1.4734781.

PMID:
28517635
23.

Reread-adapt and answer-comprehend intervention with Deaf and hard of hearing readers: effect on fluency and reading achievement.

Schirmer BR, Schaffer L, Therrien WJ, Schirmer TN.

Am Ann Deaf. 2012 Winter;156(5):469-75.

PMID:
22524092
24.

Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins.

Engel P, Goepfert A, Stanger FV, Harms A, Schmidt A, Schirmer T, Dehio C.

Nature. 2012 Jan 22;482(7383):107-10. doi: 10.1038/nature10729.

PMID:
22266942
25.

Effect of gold marker seeds on magnetic resonance spectroscopy of the prostate.

Hossain M, Schirmer T, Richardson T, Chen L, Buyyounouski MK, Ma CM.

Int J Radiat Oncol Biol Phys. 2012 May 1;83(1):451-8. doi: 10.1016/j.ijrobp.2011.06.2001. Epub 2012 Jan 13.

PMID:
22245188
26.

Oligomer formation of the bacterial second messenger c-di-GMP: reaction rates and equilibrium constants indicate a monomeric state at physiological concentrations.

Gentner M, Allan MG, Zaehringer F, Schirmer T, Grzesiek S.

J Am Chem Soc. 2012 Jan 18;134(2):1019-29. doi: 10.1021/ja207742q. Epub 2011 Dec 29.

PMID:
22142443
27.

Crystal structure of Sol I 2: a major allergen from fire ant venom.

Borer AS, Wassmann P, Schmidt M, Hoffman DR, Zhou JJ, Wright C, Schirmer T, Marković-Housley Z.

J Mol Biol. 2012 Jan 27;415(4):635-48. doi: 10.1016/j.jmb.2011.10.009. Epub 2011 Nov 12.

PMID:
22100449
28.

OsO4·streptavidin: a tunable hybrid catalyst for the enantioselective cis-dihydroxylation of olefins.

Köhler V, Mao J, Heinisch T, Pordea A, Sardo A, Wilson YM, Knörr L, Creus M, Prost JC, Schirmer T, Ward TR.

Angew Chem Int Ed Engl. 2011 Nov 11;50(46):10863-6. doi: 10.1002/anie.201103632. Epub 2011 Sep 21. No abstract available.

PMID:
21948623
29.

Regulatory cohesion of cell cycle and cell differentiation through interlinked phosphorylation and second messenger networks.

Abel S, Chien P, Wassmann P, Schirmer T, Kaever V, Laub MT, Baker TA, Jenal U.

Mol Cell. 2011 Aug 19;43(4):550-60. doi: 10.1016/j.molcel.2011.07.018.

30.

Human carbonic anhydrase II as a host for piano-stool complexes bearing a sulfonamide anchor.

Monnard FW, Heinisch T, Nogueira ES, Schirmer T, Ward TR.

Chem Commun (Camb). 2011 Aug 7;47(29):8238-40. doi: 10.1039/c1cc10345h. Epub 2011 Jun 27.

PMID:
21706094
31.

Artificial transfer hydrogenases for the enantioselective reduction of cyclic imines.

Dürrenberger M, Heinisch T, Wilson YM, Rossel T, Nogueira E, Knörr L, Mutschler A, Kersten K, Zimbron MJ, Pierron J, Schirmer T, Ward TR.

Angew Chem Int Ed Engl. 2011 Mar 21;50(13):3026-9. doi: 10.1002/anie.201007820. Epub 2011 Feb 24. No abstract available.

PMID:
21404391
32.

Fic domain-catalyzed adenylylation: insight provided by the structural analysis of the type IV secretion system effector BepA.

Palanivelu DV, Goepfert A, Meury M, Guye P, Dehio C, Schirmer T.

Protein Sci. 2011 Mar;20(3):492-9. doi: 10.1002/pro.581. Epub 2011 Feb 17.

33.

Chemo-genetic optimization of DNA recognition by metallodrugs using a presenter-protein strategy.

Zimbron JM, Sardo A, Heinisch T, Wohlschlager T, Gradinaru J, Massa C, Schirmer T, Creus M, Ward TR.

Chemistry. 2010 Nov 15;16(43):12883-9. doi: 10.1002/chem.201001573.

PMID:
20878805
34.

Efficient enzymatic production of the bacterial second messenger c-di-GMP by the diguanylate cyclase YdeH from E. coli.

Zähringer F, Massa C, Schirmer T.

Appl Biochem Biotechnol. 2011 Jan;163(1):71-9. doi: 10.1007/s12010-010-9017-x. Epub 2010 Jun 29.

PMID:
20582742
35.

Structure of the major carrot allergen Dau c 1.

Marković-Housley Z, Basle A, Padavattan S, Maderegger B, Schirmer T, Hoffmann-Sommergruber K.

Acta Crystallogr D Biol Crystallogr. 2009 Nov;65(Pt 11):1206-12. doi: 10.1107/S0907444909034854. Epub 2009 Oct 22.

PMID:
19923716
36.

NanC crystal structure, a model for outer-membrane channels of the acidic sugar-specific KdgM porin family.

Wirth C, Condemine G, Boiteux C, Bernèche S, Schirmer T, Peneff CM.

J Mol Biol. 2009 Dec 11;394(4):718-31. doi: 10.1016/j.jmb.2009.09.054. Epub 2009 Sep 29.

PMID:
19796645
37.

Structural and mechanistic determinants of c-di-GMP signalling.

Schirmer T, Jenal U.

Nat Rev Microbiol. 2009 Oct;7(10):724-35. doi: 10.1038/nrmicro2203. Review.

PMID:
19756011
38.

Second messenger signalling governs Escherichia coli biofilm induction upon ribosomal stress.

Boehm A, Steiner S, Zaehringer F, Casanova A, Hamburger F, Ritz D, Keck W, Ackermann M, Schirmer T, Jenal U.

Mol Microbiol. 2009 Jun;72(6):1500-16. doi: 10.1111/j.1365-2958.2009.06739.x. Epub 2009 May 15.

39.

Crystal structures of YkuI and its complex with second messenger cyclic Di-GMP suggest catalytic mechanism of phosphodiester bond cleavage by EAL domains.

Minasov G, Padavattan S, Shuvalova L, Brunzelle JS, Miller DJ, Baslé A, Massa C, Collart FR, Schirmer T, Anderson WF.

J Biol Chem. 2009 May 8;284(19):13174-84. doi: 10.1074/jbc.M808221200. Epub 2009 Feb 24.

40.

High-affinity IgE recognition of a conformational epitope of the major respiratory allergen Phl p 2 as revealed by X-ray crystallography.

Padavattan S, Flicker S, Schirmer T, Madritsch C, Randow S, Reese G, Vieths S, Lupinek C, Ebner C, Valenta R, Markovic-Housley Z.

J Immunol. 2009 Feb 15;182(4):2141-51. doi: 10.4049/jimmunol.0803018.

41.

FMRI indices of auditory attention in schizophrenia.

Schirmer TN, Dorflinger JM, Marlow-O'Connor M, Pendergrass JC, Hartzell A, All SD, Charles D.

Prog Neuropsychopharmacol Biol Psychiatry. 2009 Feb 1;33(1):25-32. doi: 10.1016/j.pnpbp.2008.09.028. Epub 2008 Oct 17.

PMID:
18957312
42.

Quantitative proton magnetic resonance spectroscopy of the normal liver and malignant hepatic lesions at 3.0 Tesla.

Fischbach F, Schirmer T, Thormann M, Freund T, Ricke J, Bruhn H.

Eur Radiol. 2008 Nov;18(11):2549-58. doi: 10.1007/s00330-008-1040-8. Epub 2008 May 20.

PMID:
18491103
43.

Structure of BeF3- -modified response regulator PleD: implications for diguanylate cyclase activation, catalysis, and feedback inhibition.

Wassmann P, Chan C, Paul R, Beck A, Heerklotz H, Jenal U, Schirmer T.

Structure. 2007 Aug;15(8):915-27. Erratum in: Structure. 2007 Sep;15(9):1155.

44.

Identification of a B-cell epitope of hyaluronidase, a major bee venom allergen, from its crystal structure in complex with a specific Fab.

Padavattan S, Schirmer T, Schmidt M, Akdis C, Valenta R, Mittermann I, Soldatova L, Slater J, Mueller U, Markovic-Housley Z.

J Mol Biol. 2007 May 4;368(3):742-52. Epub 2007 Feb 22.

PMID:
17374540
45.

Proton MR spectroscopy of the brain at 3 T: an update.

Di Costanzo A, Trojsi F, Tosetti M, Schirmer T, Lechner SM, Popolizio T, Scarabino T.

Eur Radiol. 2007 Jul;17(7):1651-62. Epub 2007 Jan 18. Review.

PMID:
17235536
46.

Crystal structure of osmoporin OmpC from E. coli at 2.0 A.

Baslé A, Rummel G, Storici P, Rosenbusch JP, Schirmer T.

J Mol Biol. 2006 Oct 6;362(5):933-42. Epub 2006 Aug 3.

PMID:
16949612
47.

Chronic progressive external ophthalmoplegia: MR spectroscopy and MR diffusion studies in the brain.

Heidenreich JO, Klopstock T, Schirmer T, Saemann P, Mueller-Felber W, Auer DP.

AJR Am J Roentgenol. 2006 Sep;187(3):820-4.

PMID:
16928952
48.

Conductance and selectivity fluctuations in D127 mutants of the bacterial porin OmpF.

Miedema H, Vrouenraets M, Wierenga J, Eisenberg B, Schirmer T, Baslé A, Meijberg W.

Eur Biophys J. 2006 Dec;36(1):13-22. Epub 2006 Jul 21.

PMID:
16858566
49.

Co-axial association of recombinant eye lens aquaporin-0 observed in loosely packed 3D crystals.

Palanivelu DV, Kozono DE, Engel A, Suda K, Lustig A, Agre P, Schirmer T.

J Mol Biol. 2006 Jan 27;355(4):605-11. Epub 2005 Nov 8.

PMID:
16309700
50.

Determinants of substrate specificity in omega-aminotransferases.

Markova M, Peneff C, Hewlins MJ, Schirmer T, John RA.

J Biol Chem. 2005 Oct 28;280(43):36409-16. Epub 2005 Aug 11.

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