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Items: 1 to 50 of 208

1.

Fish-gut-on-chip: development of a microfluidic bioreactor to study the role of the fish intestine in vitro.

Drieschner C, Könemann S, Renaud P, Schirmer K.

Lab Chip. 2019 Sep 4. doi: 10.1039/c9lc00415g. [Epub ahead of print]

PMID:
31482163
2.

Extending the concept of predicting fish acute toxicity in vitro to the intestinal cell line RTgutGC.

Schug H, Maner J, Hülskamp M, Begnaud F, Debonneville C, Berthaud F, Gimeno S, Schirmer K.

ALTEX. 2019 Jul 11. doi: 10.14573/altex.1905032. [Epub ahead of print]

3.

Improving a fish intestinal barrier model by combining two rainbow trout cell lines: epithelial RTgutGC and fibroblastic RTgutF.

Drieschner C, Vo NTK, Schug H, Burkard M, Bols NC, Renaud P, Schirmer K.

Cytotechnology. 2019 Jun 29:835-848. doi: 10.1007/s10616-019-00327-0. [Epub ahead of print]

4.

Imidacloprid induces adverse effects on fish early life stages that are more severe in Japanese medaka (Oryzias latipes) than in zebrafish (Danio rerio).

Vignet C, Cappello T, Fu Q, Lajoie K, De Marco G, Clérandeau C, Mottaz H, Maisano M, Hollender J, Schirmer K, Cachot J.

Chemosphere. 2019 Jun;225:470-478. doi: 10.1016/j.chemosphere.2019.03.002. Epub 2019 Mar 9.

PMID:
30897470
5.

Co-exposure to polystyrene plastic beads and polycyclic aromatic hydrocarbon contaminants in fish gill (RTgill-W1) and intestinal (RTgutGC) epithelial cells derived from rainbow trout (Oncorhynchus mykiss).

Bussolaro D, Wright SL, Schnell S, Schirmer K, Bury NR, Arlt VM.

Environ Pollut. 2019 May;248:706-714. doi: 10.1016/j.envpol.2019.02.066. Epub 2019 Feb 22.

6.

Time- and concentration-dependent expression of immune and barrier genes in the RTgutGC fish intestinal model following immune stimulation.

Schug H, Yue Y, Krese R, Fischer S, Kortner TM, Schirmer K.

Fish Shellfish Immunol. 2019 May;88:308-317. doi: 10.1016/j.fsi.2019.02.036. Epub 2019 Mar 4.

PMID:
30844464
7.

Repeatability and Reproducibility of the RTgill-W1 Cell Line Assay for Predicting Fish Acute Toxicity.

Fischer M, Belanger SE, Berckmans P, Bernhard MJ, Bláha L, Coman Schmid DE, Dyer SD, Haupt T, Hermens JLM, Hultman MT, Laue H, Lillicrap A, Mlnaříková M, Natsch A, Novák J, Sinnige TL, Tollefsen KE, von Niederhäusern V, Witters H, Županič A, Schirmer K.

Toxicol Sci. 2019 Jun 1;169(2):353-364. doi: 10.1093/toxsci/kfz057.

8.

Rainbow Trout (Oncorhynchus Mykiss) Intestinal Epithelial Cells as a Model for Studying Gut Immune Function and Effects of Functional Feed Ingredients.

Wang J, Lei P, Gamil AAA, Lagos L, Yue Y, Schirmer K, Mydland LT, Øverland M, Krogdahl Å, Kortner TM.

Front Immunol. 2019 Feb 6;10:152. doi: 10.3389/fimmu.2019.00152. eCollection 2019.

9.

Lifetime extension of humpback whale skin fibroblasts and their response to lipopolysaccharide (LPS) and a mixture of polychlorinated biphenyls (Aroclor).

Burkard M, Bengtson Nash S, Gambaro G, Whitworth D, Schirmer K.

Cell Biol Toxicol. 2019 Jan 10. doi: 10.1007/s10565-018-09457-1. [Epub ahead of print]

PMID:
30627956
10.

Importance of Toxicokinetics to Assess the Utility of Zebrafish Larvae as Model for Psychoactive Drug Screening Using Meta-Chlorophenylpiperazine (mCPP) as Example.

Kirla KT, Groh KJ, Poetzsch M, Banote RK, Stadnicka-Michalak J, Eggen RIL, Schirmer K, Kraemer T.

Front Pharmacol. 2018 Apr 26;9:414. doi: 10.3389/fphar.2018.00414. eCollection 2018.

11.

Corrigendum to "European demonstration program on the effect-based and chemical identification and monitoring of organic pollutants in European surface waters" [Sci. Total Environ. 601-602 (2017) 1849-1868].

Tousova Z, Oswald P, Slobodnik J, Blaha L, Muz M, Hu M, Brack W, Krauss M, Di Paolo C, Tarcai Z, Seiler TB, Hollert H, Koprivica S, Ahel M, Schollée JE, Hollender J, Suter MJ, Hidasi AO, Schirmer K, Sonavane M, Ait-Aissa S, Creusot N, Brion F, Froment J, Almeida AC, Thomas K, Tollefsen KE, Tufi S, Ouyang X, Leonards P, Lamoree M, Torrens VO, Kolkman A, Schriks M, Spirhanzlova P, Tindall A, Schulze T.

Sci Total Environ. 2018 Sep 1;635:1620-1621. doi: 10.1016/j.scitotenv.2018.04.356. Epub 2018 May 5. No abstract available.

PMID:
29739659
12.

Nanomaterials in the environment: Behavior, fate, bioavailability, and effects-An updated review.

Lead JR, Batley GE, Alvarez PJJ, Croteau MN, Handy RD, McLaughlin MJ, Judy JD, Schirmer K.

Environ Toxicol Chem. 2018 Aug;37(8):2029-2063. doi: 10.1002/etc.4147. Epub 2018 Jul 16. Review.

PMID:
29633323
13.

Biotransformation of Benzo[ a]pyrene by Three Rainbow Trout ( Onchorhynchus mykiss) Cell Lines and Extrapolation To Derive a Fish Bioconcentration Factor.

Stadnicka-Michalak J, Weiss FT, Fischer M, Tanneberger K, Schirmer K.

Environ Sci Technol. 2018 Mar 6;52(5):3091-3100. doi: 10.1021/acs.est.7b04548. Epub 2018 Feb 22.

PMID:
29400055
14.

Glutathione S-Transferase Protein Expression in Different Life Stages of Zebrafish (Danio rerio).

Tierbach A, Groh KJ, Schönenberger R, Schirmer K, Suter MJ.

Toxicol Sci. 2018 Apr 1;162(2):702-712. doi: 10.1093/toxsci/kfx293.

15.

A validated algorithm for selecting non-toxic chemical concentrations.

Stadnicka-Michalak J, Knöbel M, Županič A, Schirmer K.

ALTEX. 2018;35(1):37-50. doi: 10.14573/altex.1701231. Epub 2017 Jun 26.

16.

European demonstration program on the effect-based and chemical identification and monitoring of organic pollutants in European surface waters.

Tousova Z, Oswald P, Slobodnik J, Blaha L, Muz M, Hu M, Brack W, Krauss M, Di Paolo C, Tarcai Z, Seiler TB, Hollert H, Koprivica S, Ahel M, Schollée JE, Hollender J, Suter MJ, Hidasi AO, Schirmer K, Sonavane M, Ait-Aissa S, Creusot N, Brion F, Froment J, Almeida AC, Thomas K, Tollefsen KE, Tufi S, Ouyang X, Leonards P, Lamoree M, Torrens VO, Kolkman A, Schriks M, Spirhanzlova P, Tindall A, Schulze T.

Sci Total Environ. 2017 Dec 1;601-602:1849-1868. doi: 10.1016/j.scitotenv.2017.06.032. Epub 2017 Jun 15. Erratum in: Sci Total Environ. 2018 May 5;:.

PMID:
28629112
17.

A fish intestinal epithelial barrier model established from the rainbow trout (Oncorhynchus mykiss) cell line, RTgutGC.

Minghetti M, Drieschner C, Bramaz N, Schug H, Schirmer K.

Cell Biol Toxicol. 2017 Dec;33(6):539-555. doi: 10.1007/s10565-017-9385-x. Epub 2017 Mar 1.

18.

Interaction of silver nanoparticles with algae and fish cells: a side by side comparison.

Yue Y, Li X, Sigg L, Suter MJ, Pillai S, Behra R, Schirmer K.

J Nanobiotechnology. 2017 Feb 28;15(1):16. doi: 10.1186/s12951-017-0254-9.

19.

Ultrathin Alumina Membranes as Scaffold for Epithelial Cell Culture from the Intestine of Rainbow Trout.

Drieschner C, Minghetti M, Wu S, Renaud P, Schirmer K.

ACS Appl Mater Interfaces. 2017 Mar 22;9(11):9496-9505. doi: 10.1021/acsami.7b00705. Epub 2017 Mar 9.

PMID:
28244327
20.

Cell culture-based biosensing techniques for detecting toxicity in water.

Tan L, Schirmer K.

Curr Opin Biotechnol. 2017 Jun;45:59-68. doi: 10.1016/j.copbio.2016.11.026. Epub 2017 Jan 27. Review.

21.

Dose-dependent effects of morphine on lipopolysaccharide (LPS)-induced inflammation, and involvement of multixenobiotic resistance (MXR) transporters in LPS efflux in teleost fish.

Mottaz H, Schönenberger R, Fischer S, Eggen RIL, Schirmer K, Groh KJ.

Environ Pollut. 2017 Feb;221:105-115. doi: 10.1016/j.envpol.2016.11.046. Epub 2016 Dec 20.

PMID:
28010888
22.

Assessing the bioaccumulation potential of ionizable organic compounds: Current knowledge and research priorities.

Armitage JM, Erickson RJ, Luckenbach T, Ng CA, Prosser RS, Arnot JA, Schirmer K, Nichols JW.

Environ Toxicol Chem. 2017 Apr;36(4):882-897. doi: 10.1002/etc.3680. Epub 2016 Dec 19. Review.

23.

Clobetasol propionate causes immunosuppression in zebrafish (Danio rerio) at environmentally relevant concentrations.

Hidasi AO, Groh KJ, Suter MJ, Schirmer K.

Ecotoxicol Environ Saf. 2017 Apr;138:16-24. doi: 10.1016/j.ecoenv.2016.11.024. Epub 2016 Dec 22.

PMID:
27987419
24.

From the Cover: Zebrafish Larvae Are Insensitive to Stimulation by Cocaine: Importance of Exposure Route and Toxicokinetics.

Kirla KT, Groh KJ, Steuer AE, Poetzsch M, Banote RK, Stadnicka-Michalak J, Eggen RI, Schirmer K, Kraemer T.

Toxicol Sci. 2016 Nov;154(1):183-193. Epub 2016 Aug 11.

PMID:
27521082
25.

Alternative approaches to vertebrate ecotoxicity tests in the 21st century: A review of developments over the last 2 decades and current status.

Lillicrap A, Belanger S, Burden N, Pasquier DD, Embry MR, Halder M, Lampi MA, Lee L, Norberg-King T, Rattner BA, Schirmer K, Thomas P.

Environ Toxicol Chem. 2016 Nov;35(11):2637-2646. doi: 10.1002/etc.3603. Review.

PMID:
27779828
26.

Effect of media composition on bioavailability and toxicity of silver and silver nanoparticles in fish intestinal cells (RTgutGC).

Minghetti M, Schirmer K.

Nanotoxicology. 2016 Dec;10(10):1526-1534. Epub 2016 Oct 21.

PMID:
27689691
27.

Contribution of hepatic cytochrome CYP1A and metallothionein mRNA abundance to biomonitoring-A case study with European flounder (Platichthys flesus) from the Gulf of Gdańsk.

Kopecka-Pilarczyk J, Schirmer K.

Comp Biochem Physiol C Toxicol Pharmacol. 2016 Oct;188:24-9. doi: 10.1016/j.cbpc.2016.06.001. Epub 2016 Jun 5.

PMID:
27276230
28.

Cell compatible encapsulation of filaments into 3D hydrogels.

Schirmer KS, Gorkin R 3rd, Beirne S, Stewart E, Thompson BC, Quigley AF, Kapsa RM, Wallace GG.

Biofabrication. 2016 May 23;8(2):025013. doi: 10.1088/1758-5090/8/2/025013.

PMID:
27213861
29.

Erratum to: LC-MS/MS determination of potential endocrine disruptors of cortico signalling in rivers and wastewaters.

Ammann AA, Macikova P, Groh KJ, Schirmer K, Suter MJ.

Anal Bioanal Chem. 2016 Jul;408(17):4821-4822. Epub 2016 Apr 26. No abstract available.

PMID:
27116420
30.

Silver nanoparticles inhibit fish gill cell proliferation in protein-free culture medium.

Yue Y, Behra R, Sigg L, Schirmer K.

Nanotoxicology. 2016 Oct;10(8):1075-83. doi: 10.3109/17435390.2016.1172677. Epub 2016 Apr 21.

PMID:
27030289
31.

Transformation of Contaminant Candidate List (CCL3) compounds during ozonation and advanced oxidation processes in drinking water: Assessment of biological effects.

Mestankova H, Parker AM, Bramaz N, Canonica S, Schirmer K, von Gunten U, Linden KG.

Water Res. 2016 Apr 15;93:110-120. doi: 10.1016/j.watres.2015.12.048. Epub 2016 Jan 21.

PMID:
26900972
32.

An interlaboratory comparison of nanosilver characterisation and hazard identification: Harmonising techniques for high quality data.

Jemec A, Kahru A, Potthoff A, Drobne D, Heinlaan M, Böhme S, Geppert M, Novak S, Schirmer K, Rekulapally R, Singh S, Aruoja V, Sihtmäe M, Juganson K, Käkinen A, Kühnel D.

Environ Int. 2016 Feb;87:20-32. doi: 10.1016/j.envint.2015.10.014. Epub 2015 Nov 28.

33.

Toxicology across scales: Cell population growth in vitro predicts reduced fish growth.

Stadnicka-Michalak J, Schirmer K, Ashauer R.

Sci Adv. 2015 Aug 7;1(7):e1500302. doi: 10.1126/sciadv.1500302. eCollection 2015 Aug.

34.

Early life exposure to PCB126 results in delayed mortality and growth impairment in the zebrafish larvae.

Di Paolo C, Groh KJ, Zennegg M, Vermeirssen EL, Murk AJ, Eggen RI, Hollert H, Werner I, Schirmer K.

Aquat Toxicol. 2015 Dec;169:168-78. doi: 10.1016/j.aquatox.2015.10.014. Epub 2015 Oct 28.

PMID:
26551687
35.

Chemical Aspects of Nanoparticle Ecotoxicology.

Sigg L, Behra R, Groh K, Isaacson C, Odzak N, Piccapietra F, Röhder L, Schug H, Yue Y, Schirmer K.

Chimia (Aarau). 2014 Nov;68(11):806-11. doi: 10.2533/chimia.2014.806.

PMID:
26508489
36.

Scientific Basis for Regulatory Decision-Making of Nanomaterials Report on the Workshop, 20-21 January 2014, Center of Applied Ecotoxicology, Dübendorf.

Studer C, Aicher L, Gasic B, von Goetz N, Hoet P, Huwyler J, Kägi R, Kase R, Kobe A, Nowack B, Rothen-Rutishauser B, Schirmer K, Schneider G, Vermeissen E, Wick P, Walser T.

Chimia (Aarau). 2015;69(1-2):52-6. doi: 10.2533/chimia.2015.52.

PMID:
26507088
37.

In Vitro Generation of Functional Liver Organoid-Like Structures Using Adult Human Cells.

Ramachandran SD, Schirmer K, Münst B, Heinz S, Ghafoory S, Wölfl S, Simon-Keller K, Marx A, Øie CI, Ebert MP, Walles H, Braspenning J, Breitkopf-Heinlein K.

PLoS One. 2015 Oct 21;10(10):e0139345. doi: 10.1371/journal.pone.0139345. eCollection 2015.

38.

Establishment of the first humpback whale fibroblast cell lines and their application in chemical risk assessment.

Burkard M, Whitworth D, Schirmer K, Nash SB.

Aquat Toxicol. 2015 Oct;167:240-7. doi: 10.1016/j.aquatox.2015.08.005. Epub 2015 Aug 20.

PMID:
26363275
39.

Novel test procedure to evaluate the treatability of wastewater with ozone.

Schindler Wildhaber Y, Mestankova H, Schärer M, Schirmer K, Salhi E, von Gunten U.

Water Res. 2015 May 15;75:324-35. doi: 10.1016/j.watres.2015.02.030. Epub 2015 Feb 25.

PMID:
25827671
40.

Octopamine regulates antennal sensory neurons via daytime-dependent changes in cAMP and IP3 levels in the hawkmoth Manduca sexta.

Schendzielorz T, Schirmer K, Stolte P, Stengl M.

PLoS One. 2015 Mar 18;10(3):e0121230. doi: 10.1371/journal.pone.0121230. eCollection 2015.

41.

Scientific Basis for Regulatory Decision-Making of Nanomaterials Report on the Workshop, 20-21 January 2014, Center of Applied Ecotoxicology, Dübendorf.

Studer C, Aicher L, Gasic B, von Goetz N, Hoet P, Huwyler J, Kägi R, Kase R, Kobe A, Nowack B, Rothen-Rutishauser B, Schirmer K, Schneider G, Vermeissen E, Wick P, Walser T.

Chimia (Aarau). 2015 Feb 25;69(1):52-56. doi: 10.2533/chimia.2015.52.

PMID:
28982464
42.

Silver nanoparticle effects on stream periphyton during short-term exposures.

Gil-Allué C, Schirmer K, Tlili A, Gessner MO, Behra R.

Environ Sci Technol. 2015 Jan 20;49(2):1165-72.

PMID:
25513720
43.

Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: II. A focus on growth impairment in fish.

Groh KJ, Carvalho RN, Chipman JK, Denslow ND, Halder M, Murphy CA, Roelofs D, Rolaki A, Schirmer K, Watanabe KH.

Chemosphere. 2015 Feb;120:778-92. doi: 10.1016/j.chemosphere.2014.10.006. Epub 2014 Oct 30. Review.

44.

Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: I. Challenges and research needs in ecotoxicology.

Groh KJ, Carvalho RN, Chipman JK, Denslow ND, Halder M, Murphy CA, Roelofs D, Rolaki A, Schirmer K, Watanabe KH.

Chemosphere. 2015 Feb;120:764-77. doi: 10.1016/j.chemosphere.2014.09.068. Epub 2014 Nov 11. Review.

45.

LC-MS/MS determination of potential endocrine disruptors of cortico signalling in rivers and wastewaters.

Ammann AA, Macikova P, Groh KJ, Schirmer K, Suter MJ.

Anal Bioanal Chem. 2014 Nov;406(29):7653-65. doi: 10.1007/s00216-014-8206-9. Epub 2014 Oct 7. Erratum in: Anal Bioanal Chem. 2016 Jul;408(17):4821-2.

PMID:
25286876
46.

Endocrine disrupting compounds affecting corticosteroid signaling pathways in Czech and Swiss waters: potential impact on fish.

Macikova P, Groh KJ, Ammann AA, Schirmer K, Suter MJ.

Environ Sci Technol. 2014 Nov 4;48(21):12902-11. doi: 10.1021/es502711c. Epub 2014 Oct 16.

PMID:
25269596
47.

Development of mutagenicity during degradation of N-nitrosamines by advanced oxidation processes.

Mestankova H, Schirmer K, Canonica S, von Gunten U.

Water Res. 2014 Dec 1;66:399-410. doi: 10.1016/j.watres.2014.08.012. Epub 2014 Aug 21.

PMID:
25240607
48.

Effect of TiO2 nanoparticles and UV radiation on extracellular enzyme activity of intact heterotrophic biofilms.

Schug H, Isaacson CW, Sigg L, Ammann AA, Schirmer K.

Environ Sci Technol. 2014 Oct 7;48(19):11620-8. doi: 10.1021/es502620e. Epub 2014 Sep 29.

PMID:
25208344
49.

Mixtures of chemical pollutants at European legislation safety concentrations: how safe are they?

Carvalho RN, Arukwe A, Ait-Aissa S, Bado-Nilles A, Balzamo S, Baun A, Belkin S, Blaha L, Brion F, Conti D, Creusot N, Essig Y, Ferrero VE, Flander-Putrle V, Fürhacker M, Grillari-Voglauer R, Hogstrand C, Jonáš A, Kharlyngdoh JB, Loos R, Lundebye AK, Modig C, Olsson PE, Pillai S, Polak N, Potalivo M, Sanchez W, Schifferli A, Schirmer K, Sforzini S, Stürzenbaum SR, Søfteland L, Turk V, Viarengo A, Werner I, Yagur-Kroll S, Zounková R, Lettieri T.

Toxicol Sci. 2014 Sep;141(1):218-33. doi: 10.1093/toxsci/kfu118. Epub 2014 Jun 23.

50.

Effects of clofibric acid alone and in combination with 17β-estradiol on mRNA abundance in primary hepatocytes isolated from rainbow trout.

Sovadinová I, Liedtke A, Schirmer K.

Toxicol In Vitro. 2014 Sep;28(6):1106-16. doi: 10.1016/j.tiv.2014.05.002. Epub 2014 May 28.

PMID:
24880017

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