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A viral kinase counteracts in vivo restriction of murine cytomegalovirus by SAMHD1.

Deutschmann J, Schneider A, Gruska I, Vetter B, Thomas D, Kießling M, Wittmann S, Herrmann A, Schindler M, Milbradt J, Ferreirós N, Winkler TH, Wiebusch L, Gramberg T.

Nat Microbiol. 2019 Sep 23. doi: 10.1038/s41564-019-0529-z. [Epub ahead of print]


Human cytomegalovirus overcomes SAMHD1 restriction in macrophages via pUL97.

Businger R, Deutschmann J, Gruska I, Milbradt J, Wiebusch L, Gramberg T, Schindler M.

Nat Microbiol. 2019 Sep 23. doi: 10.1038/s41564-019-0557-8. [Epub ahead of print]


Flow cytometry-based FRET identifies binding intensities in PPARγ1 protein-protein interactions in living cells.

Trümper V, von Knethen A, Preuß A, Ermilov E, Hackbarth S, Kuchler L, Gunne S, Schäfer A, Bornhütter T, Vereb G, Ujlaky-Nagy L, Brüne B, Röder B, Schindler M, Parnham MJ, Knape T.

Theranostics. 2019 Jul 28;9(19):5444-5463. doi: 10.7150/thno.29367. eCollection 2019.


Glyoxalase 1 expression is downregulated in preimplantation blastocysts of diabetic rabbits.

Seeling T, Haucke E, Navarrete Santos A, Grybel KJ, Gürke J, Pendzialek SM, Schindler M, Simm A, Navarrete Santos A.

Reprod Domest Anim. 2019 Sep;54 Suppl 3:4-11. doi: 10.1111/rda.13462.


Platelets Aggregate With Neutrophils and Promote Skin Pathology in Psoriasis.

Herster F, Bittner Z, Codrea MC, Archer NK, Heister M, Löffler MW, Heumos S, Wegner J, Businger R, Schindler M, Stegner D, Schäkel K, Grabbe S, Ghoreschi K, Miller LS, Weber ANR.

Front Immunol. 2019 Aug 16;10:1867. doi: 10.3389/fimmu.2019.01867. eCollection 2019.


Exercise hypertension: Link to myocardial fibrosis in athletes?

Halle M, Esefeld K, Schindler M, Schunkert H.

Eur J Prev Cardiol. 2019 Aug 14:2047487319868795. doi: 10.1177/2047487319868795. [Epub ahead of print] No abstract available.


Analysis of IFITM-IFITM Interactions by a Flow Cytometry-Based FRET Assay.

Winkler M, Wrensch F, Bosch P, Knoth M, Schindler M, Gärtner S, Pöhlmann S.

Int J Mol Sci. 2019 Aug 8;20(16). pii: E3859. doi: 10.3390/ijms20163859.


Temporal trends in incidence of childhood cancer in Switzerland, 1985-2014.

Sommer G, Schindler M, Redmond S, Pfeiffer V, Konstantinoudis G, Ammann RA, Ansari M, Hengartner H, Michel G, Kuehni CE; Swiss Paediatric Oncology Group (SPOG).

Cancer Epidemiol. 2019 Aug;61:157-164. doi: 10.1016/j.canep.2019.06.002. Epub 2019 Jul 4.


[Neck pain: which physical therapies are recommended ?]

Lima Faria L, Berney S, Tartarat-Chapitre M, Schindler M.

Rev Med Suisse. 2019 Jun 19;15(656):1266-1271. French.


Iron and manganese present in underground water promote biochemical, genotoxic, and behavioral alterations in zebrafish (Danio rerio).

Marins K, Lazzarotto LMV, Boschetti G, Bertoncello KT, Sachett A, Schindler MSZ, Chitolina R, Regginato A, Zanatta AP, Siebel AM, Magro JD, Zanatta L.

Environ Sci Pollut Res Int. 2019 Aug;26(23):23555-23570. doi: 10.1007/s11356-019-05621-0. Epub 2019 Jun 15.


Exercise in Heart Failure-What Is the Optimal Dose to Improve Pathophysiology and Exercise Capacity?

Schindler MJ, Adams V, Halle M.

Curr Heart Fail Rep. 2019 Aug;16(4):98-107. doi: 10.1007/s11897-019-00428-z. Review.


An Initiative to Reduce Unnecessary Gadolinium-Based Contrast in Multiple Sclerosis Patients.

Rudie JD, Mattay RR, Schindler M, Steingall S, Cook TS, Loevner LA, Schnall MD, Mamourian AC, Bilello M.

J Am Coll Radiol. 2019 Sep;16(9 Pt A):1158-1164. doi: 10.1016/j.jacr.2019.04.005. Epub 2019 May 16.


The Value of Engaging the Public in CHATing About Healthcare Priorities: A Response to Recent Commentaries.

Danis M, Goold SD, Schindler M, Hurst SA.

Int J Health Policy Manag. 2019 Apr 1;8(4):250-252. doi: 10.15171/ijhpm.2018.113. No abstract available.


Pembrolizumab Treatment for Progressive Multifocal Leukoencephalopathy.

Cortese I, Muranski P, Enose-Akahata Y, Ha SK, Smith B, Monaco M, Ryschkewitsch C, Major EO, Ohayon J, Schindler MK, Beck E, Reoma LB, Jacobson S, Reich DS, Nath A.

N Engl J Med. 2019 Apr 25;380(17):1597-1605. doi: 10.1056/NEJMoa1815039. Epub 2019 Apr 10.


Genome-wide identification of alternative splicing events that regulate protein transport across the secretory pathway.

Neumann A, Schindler M, Olofsson D, Wilhelmi I, Schürmann A, Heyd F.

J Cell Sci. 2019 Apr 25;132(8). pii: jcs230201. doi: 10.1242/jcs.230201.


The formation of spinel-group minerals in contaminated soils: the sequestration of metal(loid)s by unexpected incidental nanoparticles.

Schindler M, Mantha H, Hochella MF Jr.

Geochem Trans. 2019 Mar 13;20(1):1. doi: 10.1186/s12932-019-0061-3.


[Multihospital use of imaging techniques in decentralized trauma care].

Brand J, Bernegger A, Pressinger D, Schindler M, Neubauer T.

Unfallchirurg. 2019 Apr;122(4):328-332. doi: 10.1007/s00113-019-0628-6. German.


Robust, atlas-free, automatic segmentation of brain MRI in health and disease.

Selvaganesan K, Whitehead E, DeAlwis PM, Schindler MK, Inati S, Saad ZS, Ohayon JE, Cortese ICM, Smith B, Steven Jacobson, Nath A, Reich DS, Inati S, Nair G.

Heliyon. 2019 Feb 18;5(2):e01226. doi: 10.1016/j.heliyon.2019.e01226. eCollection 2019 Feb.


Antinociceptive and anti-inflammatory activities of Philodendron bipinnatifidum Schott ex Endl (Araceae).

Scapinello J, Müller LG, Schindler MSZ, Anzollin GS, Siebel AM, Boligon AA, Niero R, Saraiva TES, Maus NP, Betti AH, Oliveira JV, Magro JD, de Oliveira D.

J Ethnopharmacol. 2019 May 23;236:21-30. doi: 10.1016/j.jep.2019.02.037. Epub 2019 Feb 22.


Release of Immunomodulatory Ebola Virus Glycoprotein-Containing Microvesicles Is Suppressed by Tetherin in a Species-Specific Manner.

Nehls J, Businger R, Hoffmann M, Brinkmann C, Fehrenbacher B, Schaller M, Maurer B, Schönfeld C, Kramer D, Hailfinger S, Pöhlmann S, Schindler M.

Cell Rep. 2019 Feb 12;26(7):1841-1853.e6. doi: 10.1016/j.celrep.2019.01.065.


Running performance in a timed city run and body composition: A cross-sectional study in more than 3000 runners.

Herrmann FR, Graf C, Karsegard VL, Mareschal J, Achamrah N, Delsoglio M, Schindler M, Pichard C, Genton L.

Nutrition. 2019 May;61:1-7. doi: 10.1016/j.nut.2018.10.022. Epub 2018 Oct 24.


Endoscopic optical coherence tomography with wide field-of-view for the morphological and functional assessment of the human tympanic membrane.

Kirsten L, Schindler M, Morgenstern J, Erkkilä MT, Golde J, Walther J, Rottmann P, Kemper M, Bornitz M, Neudert M, Zahnert T, Koch E.

J Biomed Opt. 2018 Dec;24(3):1-11. doi: 10.1117/1.JBO.24.3.031017.


Delineating Areas of Past Environmental Degradation near Smelters using Rock Coatings: A Case Study at Rouyn-Noranda, Quebec.

Leverington DW, Schindler M.

Sci Rep. 2018 Nov 26;8(1):17364. doi: 10.1038/s41598-018-35742-4.


Trophoblastic microRNAs are downregulated in a diabetic pregnancy through an inhibition of Drosha.

Pendzialek SM, Knelangen JM, Schindler M, Gürke J, Grybel KJ, Gocza E, Fischer B, Navarrete Santos A.

Mol Cell Endocrinol. 2019 Jan 15;480:167-179. doi: 10.1016/j.mce.2018.11.002. Epub 2018 Nov 14.


Tetherin Inhibits Nipah Virus but Not Ebola Virus Replication in Fruit Bat Cells.

Hoffmann M, Nehlmeier I, Brinkmann C, Krähling V, Behner L, Moldenhauer AS, Krüger N, Nehls J, Schindler M, Hoenen T, Maisner A, Becker S, Pöhlmann S.

J Virol. 2019 Jan 17;93(3). pii: e01821-18. doi: 10.1128/JVI.01821-18. Print 2019 Feb 1.


Herpesvirus trigger accelerates neuroinflammation in a nonhuman primate model of multiple sclerosis.

Leibovitch EC, Caruso B, Ha SK, Schindler MK, Lee NJ, Luciano NJ, Billioux BJ, Guy JR, Yen C, Sati P, Silva AC, Reich DS, Jacobson S.

Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):11292-11297. doi: 10.1073/pnas.1811974115. Epub 2018 Oct 15.


A short periconceptional exposure to maternal type-1 diabetes is sufficient to disrupt the feto-placental phenotype in a rabbit model.

Rousseau-Ralliard D, Couturier-Tarrade A, Thieme R, Brat R, Rolland A, Boileau P, Aubrière MC, Daniel N, Dahirel M, Derisoud E, Fournier N, Schindler M, Duranthon V, Fischer B, Santos AN, Chavatte-Palmer P.

Mol Cell Endocrinol. 2019 Jan 15;480:42-53. doi: 10.1016/j.mce.2018.10.010. Epub 2018 Oct 9.


Automated Integration of Multimodal MRI for the Probabilistic Detection of the Central Vein Sign in White Matter Lesions.

Dworkin JD, Sati P, Solomon A, Pham DL, Watts R, Martin ML, Ontaneda D, Schindler MK, Reich DS, Shinohara RT.

AJNR Am J Neuroradiol. 2018 Oct;39(10):1806-1813. doi: 10.3174/ajnr.A5765. Epub 2018 Sep 13.


Epidemiology of blood culture-proven bacterial sepsis in children in Switzerland: a population-based cohort study.

Agyeman PKA, Schlapbach LJ, Giannoni E, Stocker M, Posfay-Barbe KM, Heininger U, Schindler M, Korten I, Konetzny G, Niederer-Loher A, Kahlert CR, Donas A, Leone A, Hasters P, Relly C, Baer W, Kuehni CE, Aebi C, Berger C; Swiss Pediatric Sepsis Study.

Lancet Child Adolesc Health. 2017 Oct;1(2):124-133. doi: 10.1016/S2352-4642(17)30010-X. Epub 2017 Jul 21.


Swiss-CHAT: Citizens Discuss Priorities for Swiss Health Insurance Coverage.

Hurst SA, Schindler M, Goold SD, Danis M.

Int J Health Policy Manag. 2018 Aug 1;7(8):746-754. doi: 10.15171/ijhpm.2018.15.


Impulse response timing differences in BOLD and CBV weighted fMRI.

de Zwart JA, van Gelderen P, Schindler MK, Sati P, Liu J, Reich DS, Duyn JH.

Neuroimage. 2018 Nov 1;181:292-300. doi: 10.1016/j.neuroimage.2018.07.011. Epub 2018 Jul 5.


Spontaneously Flowing Crystal of Self-Propelled Particles.

Briand G, Schindler M, Dauchot O.

Phys Rev Lett. 2018 May 18;120(20):208001. doi: 10.1103/PhysRevLett.120.208001.


Activated integrins identify functional antigen-specific CD8+ T cells within minutes after antigen stimulation.

Dimitrov S, Gouttefangeas C, Besedovsky L, Jensen ATR, Chandran PA, Rusch E, Businger R, Schindler M, Lange T, Born J, Rammensee HG.

Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):E5536-E5545. doi: 10.1073/pnas.1720714115. Epub 2018 May 29.


Views and experiences with regard to antibiotic use of hospitalized patients in five European countries: a qualitative descriptive study.

Zanichelli V, Monnier AA, Tebano G, Stanić BM, Gyssens IC, Pulcini C, Vlahović-Palčevski V, Schindler M, Harbarth S, Hulscher M, Huttner BD.

Clin Microbiol Infect. 2019 Feb;25(2):249.e7-249.e12. doi: 10.1016/j.cmi.2018.04.030. Epub 2018 May 17.


Identification of Chronic Active Multiple Sclerosis Lesions on 3T MRI.

Absinta M, Sati P, Fechner A, Schindler MK, Nair G, Reich DS.

AJNR Am J Neuroradiol. 2018 Jul;39(7):1233-1238. doi: 10.3174/ajnr.A5660. Epub 2018 May 3.


ESCRT machinery components are required for Orthobunyavirus particle production in Golgi compartments.

Barbosa NS, Mendonça LR, Dias MVS, Pontelli MC, da Silva EZM, Criado MF, da Silva-Januário ME, Schindler M, Jamur MC, Oliver C, Arruda E, daSilva LLP.

PLoS Pathog. 2018 May 3;14(5):e1007047. doi: 10.1371/journal.ppat.1007047. eCollection 2018 May.


Spatiotemporal distribution of fibrinogen in marmoset and human inflammatory demyelination.

Lee NJ, Ha SK, Sati P, Absinta M, Luciano NJ, Lefeuvre JA, Schindler MK, Leibovitch EC, Ryu JK, Petersen MA, Silva AC, Jacobson S, Akassoglou K, Reich DS.

Brain. 2018 Jun 1;141(6):1637-1649. doi: 10.1093/brain/awy082.


A GXXXA Motif in the Transmembrane Domain of the Ebola Virus Glycoprotein Is Required for Tetherin Antagonism.

González-Hernández M, Hoffmann M, Brinkmann C, Nehls J, Winkler M, Schindler M, Pöhlmann S.

J Virol. 2018 Jun 13;92(13). pii: e00403-18. doi: 10.1128/JVI.00403-18. Print 2018 Jul 1.


Solidarity and cost management: Swiss citizens' reasons for priorities regarding health insurance coverage.

Schindler M, Danis M, Goold SD, Hurst SA.

Health Expect. 2018 Oct;21(5):858-869. doi: 10.1111/hex.12680. Epub 2018 Apr 14.


How well are Swiss French physicians prepared for future practice in primary care?

Junod Perron N, Audetat MC, Mazouri S, Schindler M, Haller DM, Sommer J.

BMC Med Educ. 2018 Apr 4;18(1):65. doi: 10.1186/s12909-018-1168-4.


Domains of the Hepatitis B Virus Small Surface Protein S Mediating Oligomerization.

Suffner S, Gerstenberg N, Patra M, Ruibal P, Orabi A, Schindler M, Bruss V.

J Virol. 2018 May 14;92(11). pii: e02232-17. doi: 10.1128/JVI.02232-17. Print 2018 Jun 1.


Early insights into the characteristics and evolution of clinical parameters in a cohort of patients prescribed sacubitril/valsartan in Germany.

Wachter R, Viriato D, Klebs S, Grunow SS, Schindler M, Engelhard J, Proenca CC, Calado F, Schlienger R, Dworak M, Balas B, Bruce Wirta S.

Postgrad Med. 2018 Apr;130(3):308-316. doi: 10.1080/00325481.2018.1442090. Epub 2018 Feb 28.


Overweight in childhood cancer survivors: the Swiss Childhood Cancer Survivor Study.

Belle FN, Weiss A, Schindler M, Goutaki M, Bochud M, Zimmermann K, von der Weid N, Ammann RA, Kuehni CE.

Am J Clin Nutr. 2018 Jan 1;107(1):3-11. doi: 10.1093/ajcn/nqx006.


Links between seawater flooding, soil ammonia oxidiser communities and their response to changes in salinity.

Nacke H, Schöning I, Schindler M, Schrumpf M, Daniel R, Nicol GW, Prosser JI.

FEMS Microbiol Ecol. 2017 Nov 1;93(11). doi: 10.1093/femsec/fix144.


Dual role of the chromatin-binding factor PHF13 in the pre- and post-integration phases of HIV-1 replication.

Hofmann S, Dehn S, Businger R, Bolduan S, Schneider M, Debyser Z, Brack-Werner R, Schindler M.

Open Biol. 2017 Oct;7(10). pii: 170115. doi: 10.1098/rsob.170115.


Agonism of free fatty acid receptors 1 and 4 generates peptide YY-mediated inhibitory responses in mouse colon.

Moodaley R, Smith DM, Tough IR, Schindler M, Cox HM.

Br J Pharmacol. 2017 Dec;174(23):4508-4522. doi: 10.1111/bph.14054. Epub 2017 Nov 8.


T cells with low CD2 levels express reduced restriction factors and are preferentially infected in therapy naïve chronic HIV-1 patients.

Bolduan S, Koppensteiner H, Businger R, Rebensburg S, Kunze C, Brack-Werner R, Draenert R, Schindler M.

J Int AIDS Soc. 2017 Sep 19;20(1):21865. doi: 10.7448/IAS.20.1.21865.


Long-term pulmonary disease among Swiss childhood cancer survivors.

Kasteler R, Weiss A, Schindler M, Sommer G, Latzin P, von der Weid NX, Ammann RA, Kuehni CE; Swiss Pediatric Oncology Group (SPOG).

Pediatr Blood Cancer. 2018 Jan;65(1). doi: 10.1002/pbc.26749. Epub 2017 Sep 4.


The Long-Term Effect of the Periconception Period on the Embryo's Epigenetic Profile and Phenotype: The Role of Maternal Disease Such as Diabetes and How the Effect Is Mediated (Example from a Rabbit Model).

Fischer B, Schindler M, Mareike Pendzialek S, Gürke J, Haucke E, Grybel KJ, Thieme R, Santos AN.

Adv Exp Med Biol. 2017;1014:107-115. doi: 10.1007/978-3-319-62414-3_6. Review.


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