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Items: 1 to 50 of 52

1.

Frontline Science: Acyl-CoA synthetase 1 exacerbates lipotoxic inflammasome activation in primary macrophages.

Kalugotla G, He L, Weber KJ, Daemen S, Reller A, Razani B, Schilling JD.

J Leukoc Biol. 2019 Jun 5. doi: 10.1002/JLB.3HI0219-045RR. [Epub ahead of print]

PMID:
31166619
2.

PPARγ Deficiency Suppresses the Release of IL-1β and IL-1α in Macrophages via a Type 1 IFN-Dependent Mechanism.

Weber KJ, Sauer M, He L, Tycksen E, Kalugotla G, Razani B, Schilling JD.

J Immunol. 2018 Oct 1;201(7):2054-2069. doi: 10.4049/jimmunol.1800224. Epub 2018 Aug 24.

PMID:
30143592
3.

A novel genetic marker of decreased inflammation and improved survival after acute myocardial infarction.

Coverstone ED, Bach RG, Chen L, Bierut LJ, Li AY, Lenzini PA, O'Neill HC, Spertus JA, Sucharov CC, Stitzel JA, Schilling JD, Cresci S.

Basic Res Cardiol. 2018 Aug 10;113(5):38. doi: 10.1007/s00395-018-0697-7.

PMID:
30097758
4.

The Hemodynamic Profile of GI Bleeding in Continuous-Flow LVADs: Is it All About the Right Ventricle?

Sparrow CT, Schilling JD.

J Card Fail. 2018 Aug;24(8):494-495. doi: 10.1016/j.cardfail.2018.07.007. Epub 2018 Aug 2. No abstract available.

PMID:
30076881
5.

Modulation of subsets of cardiac B lymphocytes improves cardiac function after acute injury.

Adamo L, Staloch LJ, Rocha-Resende C, Matkovich SJ, Jiang W, Bajpai G, Weinheimer CJ, Kovacs A, Schilling JD, Barger PM, Bhattacharya D, Mann DL.

JCI Insight. 2018 Jun 7;3(11). pii: 120137. doi: 10.1172/jci.insight.120137. eCollection 2018 Jun 7.

6.

Intersection of Pulmonary Hypertension and Right Ventricular Dysfunction in Patients on Left Ventricular Assist Device Support: Is There a Role for Pulmonary Vasodilators?

Sparrow CT, LaRue SJ, Schilling JD.

Circ Heart Fail. 2018 Jan;11(1):e004255. doi: 10.1161/CIRCHEARTFAILURE.117.004255. Review.

PMID:
29321132
7.

Sildenafil in Left Ventricular Assist Device Is Safe and Well-Tolerated.

Ravichandran AK, LaRue SJ, Novak E, Joseph SA, Schilling JD.

ASAIO J. 2018 Mar/Apr;64(2):280-281. doi: 10.1097/MAT.0000000000000626.

PMID:
28692527
8.

Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis.

Sergin I, Evans TD, Zhang X, Bhattacharya S, Stokes CJ, Song E, Ali S, Dehestani B, Holloway KB, Micevych PS, Javaheri A, Crowley JR, Ballabio A, Schilling JD, Epelman S, Weihl CC, Diwan A, Fan D, Zayed MA, Razani B.

Nat Commun. 2017 Jun 7;8:15750. doi: 10.1038/ncomms15750.

9.

Inhibition of mTOR reduces lipotoxic cell death in primary macrophages through an autophagy-independent mechanism.

He L, Weber KJ, Diwan A, Schilling JD.

J Leukoc Biol. 2016 Nov;100(5):1113-1124. Epub 2016 Jun 16.

10.

Integrating immunometabolism and macrophage diversity.

Artyomov MN, Sergushichev A, Schilling JD.

Semin Immunol. 2016 Oct;28(5):417-424. doi: 10.1016/j.smim.2016.10.004. Epub 2016 Oct 19. Review.

11.

Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation.

Huang SC, Smith AM, Everts B, Colonna M, Pearce EL, Schilling JD, Pearce EJ.

Immunity. 2016 Oct 18;45(4):817-830. doi: 10.1016/j.immuni.2016.09.016.

13.

Slicing Into Human Translational Cardiovascular Biology.

Lavine KJ, Schilling JD.

JACC Basic Transl Sci. 2016 Apr 25;1(3):168-169. doi: 10.1016/j.jacbts.2016.03.007. eCollection 2016 Apr. No abstract available.

14.

Glutamine Modulates Macrophage Lipotoxicity.

He L, Weber KJ, Schilling JD.

Nutrients. 2016 Apr 12;8(4):215. doi: 10.3390/nu8040215.

15.

Pre-Operative Right Ventricular Dysfunction Is Associated With Gastrointestinal Bleeding in Patients Supported With Continuous-Flow Left Ventricular Assist Devices.

Sparrow CT, Nassif ME, Raymer DS, Novak E, LaRue SJ, Schilling JD.

JACC Heart Fail. 2015 Dec;3(12):956-64. doi: 10.1016/j.jchf.2015.09.009. Epub 2015 Nov 11.

16.

Prognostic utility of novel biomarkers of cardiovascular stress in patients with aortic stenosis undergoing valve replacement.

Lindman BR, Breyley JG, Schilling JD, Vatterott AM, Zajarias A, Maniar HS, Damiano RJ Jr, Moon MR, Lawton JS, Gage BF, Sintek MA, Aquino A, Holley CL, Patel NM, Lawler C, Lasala JM, Novak E.

Heart. 2015 Sep;101(17):1382-8. doi: 10.1136/heartjnl-2015-307742. Epub 2015 Jun 2.

17.

The mitochondria in diabetic heart failure: from pathogenesis to therapeutic promise.

Schilling JD.

Antioxid Redox Signal. 2015 Jun 10;22(17):1515-26. doi: 10.1089/ars.2015.6294. Epub 2015 Apr 15. Review.

18.

Treatment of secondary pulmonary hypertension with bosentan after left ventricular assist device implantation.

LaRue SJ, Garcia-Cortes R, Nassif ME, Vader JM, Ray S, Ravichandran A, Rasalingham R, Silvestry SC, Ewald GA, Wang IW, Schilling JD.

Cardiovasc Ther. 2015 Apr;33(2):50-5. doi: 10.1111/1755-5922.12111.

PMID:
25759010
19.

ATG16L1 deficiency in macrophages drives clearance of uropathogenic E. coli in an IL-1β-dependent manner.

Symington JW, Wang C, Twentyman J, Owusu-Boaitey N, Schwendener R, Núñez G, Schilling JD, Mysorekar IU.

Mucosal Immunol. 2015 Nov;8(6):1388-99. doi: 10.1038/mi.2015.7. Epub 2015 Feb 11.

20.

Distinct lysosome phenotypes influence inflammatory function in peritoneal and bone marrow-derived macrophages.

Weber K, Schilling JD.

Int J Inflam. 2014;2014:154936. doi: 10.1155/2014/154936. Epub 2014 Dec 23.

21.

Distinct macrophage lineages contribute to disparate patterns of cardiac recovery and remodeling in the neonatal and adult heart.

Lavine KJ, Epelman S, Uchida K, Weber KJ, Nichols CG, Schilling JD, Ornitz DM, Randolph GJ, Mann DL.

Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):16029-34. doi: 10.1073/pnas.1406508111. Epub 2014 Oct 27. Erratum in: Proc Natl Acad Sci U S A. 2016 Mar 8;113(10):E1414. Dosage error in article text.

22.

Lysosomes integrate metabolic-inflammatory cross-talk in primary macrophage inflammasome activation.

Weber K, Schilling JD.

J Biol Chem. 2014 Mar 28;289(13):9158-71. doi: 10.1074/jbc.M113.531202. Epub 2014 Feb 15.

23.

Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation.

Epelman S, Lavine KJ, Beaudin AE, Sojka DK, Carrero JA, Calderon B, Brija T, Gautier EL, Ivanov S, Satpathy AT, Schilling JD, Schwendener R, Sergin I, Razani B, Forsberg EC, Yokoyama WM, Unanue ER, Colonna M, Randolph GJ, Mann DL.

Immunity. 2014 Jan 16;40(1):91-104. doi: 10.1016/j.immuni.2013.11.019.

24.

Hemolysis in left ventricular assist device: a retrospective analysis of outcomes.

Ravichandran AK, Parker J, Novak E, Joseph SM, Schilling JD, Ewald GA, Silvestry S.

J Heart Lung Transplant. 2014 Jan;33(1):44-50. doi: 10.1016/j.healun.2013.08.019. Epub 2013 Nov 14.

PMID:
24418733
25.

Rituximab is associated with improved survival in cardiac allograft patients with antibody-mediated rejection: a single center review.

Ravichandran AK, Schilling JD, Novak E, Pfeifer J, Ewald GA, Joseph SM.

Clin Transplant. 2013 Nov-Dec;27(6):961-7. doi: 10.1111/ctr.12277. Epub 2013 Nov 9.

PMID:
24304378
26.

TLR4 activation under lipotoxic conditions leads to synergistic macrophage cell death through a TRIF-dependent pathway.

Schilling JD, Machkovech HM, He L, Diwan A, Schaffer JE.

J Immunol. 2013 Feb 1;190(3):1285-96. doi: 10.4049/jimmunol.1202208. Epub 2012 Dec 28.

27.

Palmitate and lipopolysaccharide trigger synergistic ceramide production in primary macrophages.

Schilling JD, Machkovech HM, He L, Sidhu R, Fujiwara H, Weber K, Ory DS, Schaffer JE.

J Biol Chem. 2013 Feb 1;288(5):2923-32. doi: 10.1074/jbc.M112.419978. Epub 2012 Dec 18.

28.

Macrophages modulate cardiac function in lipotoxic cardiomyopathy.

Schilling JD, Machkovech HM, Kim AH, Schwendener R, Schaffer JE.

Am J Physiol Heart Circ Physiol. 2012 Dec 1;303(11):H1366-73. doi: 10.1152/ajpheart.00111.2012. Epub 2012 Oct 5. Erratum in: Am J Physiol Heart Circ Physiol. 2013 Feb 15;304(4):H632. Schwedwener, Reto [corrected to Schwendener, Reto].

29.

Diabetic cardiomyopathy: bench to bedside.

Schilling JD, Mann DL.

Heart Fail Clin. 2012 Oct;8(4):619-31. doi: 10.1016/j.hfc.2012.06.007. Epub 2012 Aug 9. Review.

30.

Fatty acid synthase modulates homeostatic responses to myocardial stress.

Razani B, Zhang H, Schulze PC, Schilling JD, Verbsky J, Lodhi IJ, Topkara VK, Feng C, Coleman T, Kovacs A, Kelly DP, Saffitz JE, Dorn GW 2nd, Nichols CG, Semenkovich CF.

J Biol Chem. 2011 Sep 2;286(35):30949-61. doi: 10.1074/jbc.M111.230508. Epub 2011 Jul 8.

31.

Cardiac lipin 1 expression is regulated by the peroxisome proliferator activated receptor γ coactivator 1α/estrogen related receptor axis.

Mitra MS, Schilling JD, Wang X, Jay PY, Huss JM, Su X, Finck BN.

J Mol Cell Cardiol. 2011 Jul;51(1):120-8. doi: 10.1016/j.yjmcc.2011.04.009. Epub 2011 Apr 28.

32.

Legitimate data in remote monitoring.

Schilling JD.

Conf Proc IEEE Eng Med Biol Soc. 2009;2009:713-6. doi: 10.1109/IEMBS.2009.5332686.

PMID:
19963725
33.

Right coronary artery to coronary sinus fistula by transesophageal echocardiogram, cardiac magnetic resonance imaging, and coronary angiography.

Schilling JD, Billadello JJ.

Clin Cardiol. 2009 Jul;32(7):E29-30. doi: 10.1002/clc.20199. No abstract available.

34.

Intracellular bacterial biofilm-like pods in urinary tract infections.

Anderson GG, Palermo JJ, Schilling JD, Roth R, Heuser J, Hultgren SJ.

Science. 2003 Jul 4;301(5629):105-7.

35.

Toll-like receptor 4 on stromal and hematopoietic cells mediates innate resistance to uropathogenic Escherichia coli.

Schilling JD, Martin SM, Hung CS, Lorenz RG, Hultgren SJ.

Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4203-8. Epub 2003 Mar 24.

36.

CD14- and Toll-like receptor-dependent activation of bladder epithelial cells by lipopolysaccharide and type 1 piliated Escherichia coli.

Schilling JD, Martin SM, Hunstad DA, Patel KP, Mulvey MA, Justice SS, Lorenz RG, Hultgren SJ.

Infect Immun. 2003 Mar;71(3):1470-80.

37.

Recent advances in the molecular basis of pathogen recognition and host responses in the urinary tract.

Schilling JD, Hultgren SJ, Lorenz RG.

Int Rev Immunol. 2002 Jul-Oct;21(4-5):291-304. Review. No abstract available.

PMID:
12486816
39.
40.
41.

Dynamic interactions between host and pathogen during acute urinary tract infections.

Schilling JD, Mulvey MA, Hultgren SJ.

Urology. 2001 Jun;57(6 Suppl 1):56-61. Review.

PMID:
11378051
42.

Structure and function of Escherichia coli type 1 pili: new insight into the pathogenesis of urinary tract infections.

Schilling JD, Mulvey MA, Hultgren SJ.

J Infect Dis. 2001 Mar 1;183 Suppl 1:S36-40. Review. No abstract available.

PMID:
11171011
43.

Bacterial invasion augments epithelial cytokine responses to Escherichia coli through a lipopolysaccharide-dependent mechanism.

Schilling JD, Mulvey MA, Vincent CD, Lorenz RG, Hultgren SJ.

J Immunol. 2001 Jan 15;166(2):1148-55.

44.

Bad bugs and beleaguered bladders: interplay between uropathogenic Escherichia coli and innate host defenses.

Mulvey MA, Schilling JD, Martinez JJ, Hultgren SJ.

Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):8829-35. Review.

45.

Type 1 pilus-mediated bacterial invasion of bladder epithelial cells.

Martinez JJ, Mulvey MA, Schilling JD, Pinkner JS, Hultgren SJ.

EMBO J. 2000 Jun 15;19(12):2803-12.

46.

Bacterial pili: molecular mechanisms of pathogenesis.

Sauer FG, Mulvey MA, Schilling JD, Martinez JJ, Hultgren SJ.

Curr Opin Microbiol. 2000 Feb;3(1):65-72. Review.

PMID:
10679419
47.

Vitamin E levels in human atherosclerotic plaque: the influence of risk factors.

Killion SL, Hunter GC, Eskelson CD, Dubick MA, Putnam CW, Hall KA, Luedke CA, Misiorowski RL, Schilling JD, McIntyre KE.

Atherosclerosis. 1996 Oct 25;126(2):289-97.

PMID:
8902154
48.

Fc receptor-induced expression of Fas ligand on activated NK cells facilitates cell-mediated cytotoxicity and subsequent autocrine NK cell apoptosis.

Eischen CM, Schilling JD, Lynch DH, Krammer PH, Leibson PJ.

J Immunol. 1996 Apr 15;156(8):2693-9.

PMID:
8609385
49.

MR angiography of the foot and ankle.

Unger EC, Schilling JD, Awad AN, McIntyre KE, Yoshino MT, Pond GD, Darkazanli A, Hunter GC, Bernhard VM.

J Magn Reson Imaging. 1995 Jan-Feb;5(1):1-5.

PMID:
7696797
50.

Catheter-directed urokinase thrombolysis: an adjunct to PTA/surgery for management of lower extremity thromboembolic disease.

Schilling JD, Pond GD, Mulcahy MM, McIntyre KE, Hunter GC, Bernhard VM.

Angiology. 1994 Oct;45(10):851-60.

PMID:
7943936

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