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Items: 1 to 50 of 98

1.

Prioritization of Variants for Investigation of Genotype-Directed Nutrition in Human Superpopulations.

Nilsson PD, Newsome JM, Santos HM, Schiller MR.

Int J Mol Sci. 2019 Jul 18;20(14). pii: E3516. doi: 10.3390/ijms20143516.

2.

The carboxy-terminus, a key regulator of protein function.

Sharma S, Schiller MR.

Crit Rev Biochem Mol Biol. 2019 Apr;54(2):85-102. doi: 10.1080/10409238.2019.1586828. Epub 2019 May 20.

3.

Minimotifs dysfunction is pervasive in neurodegenerative disorders.

Sharma S, Young RJ, Chen J, Chen X, Oh EC, Schiller MR.

Alzheimers Dement (N Y). 2018 Jul 25;4:414-432. doi: 10.1016/j.trci.2018.06.005. eCollection 2018.

4.

Minimotif Miner 4: a million peptide minimotifs and counting.

Lyon KF, Cai X, Young RJ, Mamun AA, Rajasekaran S, Schiller MR.

Nucleic Acids Res. 2018 Jan 4;46(D1):D465-D470. doi: 10.1093/nar/gkx1085.

5.

The minimotif synthesis hypothesis for the origin of life.

Schiller MR.

J Transl Sci. 2016;2(5):289-296. doi: 10.15761/JTS.1000154. Epub 2016 Jul 19.

6.

TALEN gene editing takes aim on HIV.

Benjamin R, Berges BK, Solis-Leal A, Igbinedion O, Strong CL, Schiller MR.

Hum Genet. 2016 Sep;135(9):1059-70. doi: 10.1007/s00439-016-1678-2. Epub 2016 May 12. Review.

7.

The Functional Human C-Terminome.

Sharma S, Toledo O, Hedden M, Lyon KF, Brooks SB, David RP, Limtong J, Newsome JM, Novakovic N, Rajasekaran S, Thapar V, Williams SR, Schiller MR.

PLoS One. 2016 Apr 6;11(4):e0152731. doi: 10.1371/journal.pone.0152731. eCollection 2016.

8.

Natural variability of minimotifs in 1092 people indicates that minimotifs are targets of evolution.

Lyon KF, Strong CL, Schooler SG, Young RJ, Roy N, Ozar B, Bachmeier M 2nd, Rajasekaran S, Schiller MR.

Nucleic Acids Res. 2015 Jul 27;43(13):6399-412. doi: 10.1093/nar/gkv580. Epub 2015 Jun 11.

9.

Damaging the Integrated HIV Proviral DNA with TALENs.

Strong CL, Guerra HP, Mathew KR, Roy N, Simpson LR, Schiller MR.

PLoS One. 2015 May 6;10(5):e0125652. doi: 10.1371/journal.pone.0125652. eCollection 2015.

10.

The HIVToolbox 2 web system integrates sequence, structure, function and mutation analysis.

Sargeant DP, Deverasetty S, Strong CL, Alaniz IJ, Bartlett A, Brandon NR, Brooks SB, Brown FA, Bufi F, Chakarova M, David RP, Dobritch KM, Guerra HP, Hedden MW, Kumra R, Levitt KS, Mathew KR, Matti R, Maza DQ, Mistry S, Novakovic N, Pomerantz A, Portillo J, Rafalski TF, Rathnayake VR, Rezapour N, Songao S, Tuggle SL, Yousif S, Dorsky DI, Schiller MR.

PLoS One. 2014 Jun 2;9(6):e98810. doi: 10.1371/journal.pone.0098810. eCollection 2014.

11.

The Geogenomic Mutational Atlas of Pathogens (GoMAP) web system.

Sargeant DP, Hedden MW, Deverasetty S, Strong CL, Alaniz IJ, Bartlett AN, Brandon NR, Brooks SB, Brown FA, Bufi F, Chakarova M, David RP, Dobritch KM, Guerra HP, Levit KS, Mathew KR, Matti R, Maza DQ, Mistry S, Novakovic N, Pomerantz A, Rafalski TF, Rathnayake V, Rezapour N, Ross CA, Schooler SG, Songao S, Tuggle SL, Wing HJ, Yousif S, Schiller MR.

PLoS One. 2014 Mar 27;9(3):e92877. doi: 10.1371/journal.pone.0092877. eCollection 2014.

12.

Granularity analysis for mathematical proofs.

Schiller MR.

Top Cogn Sci. 2013 Apr;5(2):251-69. doi: 10.1111/tops.12012. Epub 2013 Mar 4.

13.

Secondary structure, a missing component of sequence-based minimotif definitions.

Sargeant DP, Gryk MR, Maciejewski MW, Thapar V, Kundeti V, Rajasekaran S, Romero P, Dunker K, Li SC, Kaneko T, Schiller MR.

PLoS One. 2012;7(12):e49957. doi: 10.1371/journal.pone.0049957. Epub 2012 Dec 7.

14.

Achieving high accuracy prediction of minimotifs.

Mi T, Rajasekaran S, Merlin JC, Gryk M, Schiller MR.

PLoS One. 2012;7(9):e45589. doi: 10.1371/journal.pone.0045589. Epub 2012 Sep 27.

15.

Reducing false-positive prediction of minimotifs with a genetic interaction filter.

Merlin JC, Rajasekaran S, Mi T, Schiller MR.

PLoS One. 2012;7(3):e32630. doi: 10.1371/journal.pone.0032630. Epub 2012 Mar 5.

16.

N-terminal Dbl domain of the RhoGEF, Kalirin.

Gorbatyuk VY, Schiller MR, Gorbatyuk OI, Barwinski M, Hoch JC.

J Biomol NMR. 2012 Mar;52(3):269-76. doi: 10.1007/s10858-012-9605-x. No abstract available.

17.

An Open-Source Sandbox for Increasing the Accessibility of Functional Programming to the Bioinformatics and Scientific Communities.

Fenwick M, Sesanker C, Schiller MR, Ellis HJ, Hinman ML, Vyas J, Gryk MR.

Proc Int Conf Inf Technol New Gener. 2012;2012:89-94.

18.

The human phosphotyrosine signaling network: evolution and hotspots of hijacking in cancer.

Li L, Tibiche C, Fu C, Kaneko T, Moran MF, Schiller MR, Li SS, Wang E.

Genome Res. 2012 Jul;22(7):1222-30. doi: 10.1101/gr.128819.111. Epub 2011 Dec 22.

19.

Minimotif Miner 3.0: database expansion and significantly improved reduction of false-positive predictions from consensus sequences.

Mi T, Merlin JC, Deverasetty S, Gryk MR, Bill TJ, Brooks AW, Lee LY, Rathnayake V, Ross CA, Sargeant DP, Strong CL, Watts P, Rajasekaran S, Schiller MR.

Nucleic Acids Res. 2012 Jan;40(Database issue):D252-60. doi: 10.1093/nar/gkr1189. Epub 2011 Dec 6.

20.

HIVToolbox, an integrated web application for investigating HIV.

Sargeant D, Deverasetty S, Luo Y, Villahoz Baleta A, Zobrist S, Rathnayake V, Russo JC, Vyas J, Muesing MA, Schiller MR.

PLoS One. 2011;6(5):e20122. doi: 10.1371/journal.pone.0020122. Epub 2011 May 25.

21.

SciReader enables reading of medical content with instantaneous definitions.

Gradie PR, Litster M, Thomas R, Vyas J, Schiller MR.

BMC Med Inform Decis Mak. 2011 Jan 25;11:4. doi: 10.1186/1472-6947-11-4.

22.

Loss-of-function mutations of ILDR1 cause autosomal-recessive hearing impairment DFNB42.

Borck G, Ur Rehman A, Lee K, Pogoda HM, Kakar N, von Ameln S, Grillet N, Hildebrand MS, Ahmed ZM, Nürnberg G, Ansar M, Basit S, Javed Q, Morell RJ, Nasreen N, Shearer AE, Ahmad A, Kahrizi K, Shaikh RS, Ali RA, Khan SN, Goebel I, Meyer NC, Kimberling WJ, Webster JA, Stephan DA, Schiller MR, Bahlo M, Najmabadi H, Gillespie PG, Nürnberg P, Wollnik B, Riazuddin S, Smith RJ, Ahmad W, Müller U, Hammerschmidt M, Friedman TB, Riazuddin S, Leal SM, Ahmad J, Kubisch C.

Am J Hum Genet. 2011 Feb 11;88(2):127-37. doi: 10.1016/j.ajhg.2010.12.011. Epub 2011 Jan 20.

23.

A computational tool for identifying minimotifs in protein-protein interactions and improving the accuracy of minimotif predictions.

Rajasekaran S, Merlin JC, Kundeti V, Mi T, Oommen A, Vyas J, Alaniz I, Chung K, Chowdhury F, Deverasatty S, Irvey TM, Lacambacal D, Lara D, Panchangam S, Rathnayake V, Watts P, Schiller MR.

Proteins. 2011 Jan;79(1):153-64. doi: 10.1002/prot.22868. Epub 2010 Oct 11.

24.
25.

Partitioning of minimotifs based on function with improved prediction accuracy.

Rajasekaran S, Mi T, Merlin JC, Oommen A, Gradie P, Schiller MR.

PLoS One. 2010 Aug 19;5(8):e12276. doi: 10.1371/journal.pone.0012276.

26.

MimoSA: a system for minimotif annotation.

Vyas J, Nowling RJ, Meusburger T, Sargeant D, Kadaveru K, Gryk MR, Kundeti V, Rajasekaran S, Schiller MR.

BMC Bioinformatics. 2010 Jun 16;11:328. doi: 10.1186/1471-2105-11-328.

27.

Loops govern SH2 domain specificity by controlling access to binding pockets.

Kaneko T, Huang H, Zhao B, Li L, Liu H, Voss CK, Wu C, Schiller MR, Li SS.

Sci Signal. 2010 May 4;3(120):ra34. doi: 10.1126/scisignal.2000796.

28.

VENN, a tool for titrating sequence conservation onto protein structures.

Vyas J, Gryk MR, Schiller MR.

Nucleic Acids Res. 2009 Oct;37(18):e124. doi: 10.1093/nar/gkp616. Epub 2009 Aug 5.

29.

A proposed syntax for Minimotif Semantics, version 1.

Vyas J, Nowling RJ, Maciejewski MW, Rajasekaran S, Gryk MR, Schiller MR.

BMC Genomics. 2009 Aug 5;10:360. doi: 10.1186/1471-2164-10-360.

30.

Structural conservation of a short, functional, peptide-sequence motif.

Fox-Erlich S, Schiller MR, Gryk MR.

Front Biosci (Landmark Ed). 2009 Jan 1;14:1143-51. Review.

31.

Minimotif miner 2nd release: a database and web system for motif search.

Rajasekaran S, Balla S, Gradie P, Gryk MR, Kadaveru K, Kundeti V, Maciejewski MW, Mi T, Rubino N, Vyas J, Schiller MR.

Nucleic Acids Res. 2009 Jan;37(Database issue):D185-90. doi: 10.1093/nar/gkn865. Epub 2008 Oct 31.

32.

Autonomous functions for the Sec14p/spectrin-repeat region of Kalirin.

Schiller MR, Ferraro F, Wang Y, Ma XM, McPherson CE, Sobota JA, Schiller NI, Mains RE, Eipper BA.

Exp Cell Res. 2008 Aug 15;314(14):2674-91. doi: 10.1016/j.yexcr.2008.05.011. Epub 2008 May 29.

33.

Viral infection and human disease--insights from minimotifs.

Kadaveru K, Vyas J, Schiller MR.

Front Biosci. 2008 May 1;13:6455-71. Review.

34.

Minimotif miner: a computational tool to investigate protein function, disease, and genetic diversity.

Schiller MR.

Curr Protoc Protein Sci. 2007 May;Chapter 2:Unit 2.12. doi: 10.1002/0471140864.ps0212s48.

PMID:
18429315
35.

RESP18, a homolog of the luminal domain IA-2, is found in dense core vesicles in pancreatic islet cells and is induced by high glucose.

Zhang G, Hirai H, Cai T, Miura J, Yu P, Huang H, Schiller MR, Swaim WD, Leapman RD, Notkins AL.

J Endocrinol. 2007 Nov;195(2):313-21.

PMID:
17951542
36.

High-throughput phosphotyrosine profiling using SH2 domains.

Machida K, Thompson CM, Dierck K, Jablonowski K, Kärkkäinen S, Liu B, Zhang H, Nash PD, Newman DK, Nollau P, Pawson T, Renkema GH, Saksela K, Schiller MR, Shin DG, Mayer BJ.

Mol Cell. 2007 Jun 22;26(6):899-915.

37.

Coupling receptor tyrosine kinases to Rho GTPases--GEFs what's the link.

Schiller MR.

Cell Signal. 2006 Nov;18(11):1834-43. Epub 2006 May 24. Review.

PMID:
16725310
38.

Regulation of RhoGEF activity by intramolecular and intermolecular SH3 domain interactions.

Schiller MR, Chakrabarti K, King GF, Schiller NI, Eipper BA, Maciejewski MW.

J Biol Chem. 2006 Jul 7;281(27):18774-86. Epub 2006 Apr 27.

39.

Minimotif Miner: a tool for investigating protein function.

Balla S, Thapar V, Verma S, Luong T, Faghri T, Huang CH, Rajasekaran S, del Campo JJ, Shinn JH, Mohler WA, Maciejewski MW, Gryk MR, Piccirillo B, Schiller SR, Schiller MR.

Nat Methods. 2006 Mar;3(3):175-7.

PMID:
16489333
40.

E-cheating: electronic plagiarism.

Schiller MR.

J Am Diet Assoc. 2005 Jul;105(7):1058, 1059-62. No abstract available.

PMID:
15983517
41.

Induction of lamellipodia by Kalirin does not require its guanine nucleotide exchange factor activity.

Schiller MR, Blangy A, Huang J, Mains RE, Eipper BA.

Exp Cell Res. 2005 Jul 15;307(2):402-17. Epub 2005 Apr 21.

PMID:
15950621
42.

Critical role for Kalirin in nerve growth factor signaling through TrkA.

Chakrabarti K, Lin R, Schiller NI, Wang Y, Koubi D, Fan YX, Rudkin BB, Johnson GR, Schiller MR.

Mol Cell Biol. 2005 Jun;25(12):5106-18.

43.
44.

Dietetic technicians report low to moderate levels of burnout.

Fall ML, Wolf KN, Schiller MR, Wilson SL.

J Am Diet Assoc. 2003 Nov;103(11):1520-2.

PMID:
14576719
45.

Rapid induction of dendritic spine morphogenesis by trans-synaptic ephrinB-EphB receptor activation of the Rho-GEF kalirin.

Penzes P, Beeser A, Chernoff J, Schiller MR, Eipper BA, Mains RE, Huganir RL.

Neuron. 2003 Jan 23;37(2):263-74.

46.
47.

Expression of multiple larger-sized transcripts for several genes in oligodendrogliomas: potential markers for glioma subtype.

Xu X, Joh HD, Pin S, Schiller NI, Prange C, Burger PC, Schiller MR.

Cancer Lett. 2001 Sep 28;171(1):67-77.

PMID:
11485829
48.
49.

Humoral autoreactivity to an alternatively spliced variant of ICA512/IA-2 in Type I diabetes.

Park YS, Kawasaki E, Kelemen K, Yu L, Schiller MR, Rewers M, Mizuta M, Eisenbarth GS, Hutton JC.

Diabetologia. 2000 Oct;43(10):1293-301.

PMID:
11079748
50.

Clinical nutrition managers have access to sources of empowerment.

Mislevy JM, Schiller MR, Wolf KN, Finn SC.

J Am Diet Assoc. 2000 Sep;100(9):1038-43.

PMID:
11019351

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