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Items: 28

1.

A cellular census of human lungs identifies novel cell states in health and in asthma.

Vieira Braga FA, Kar G, Berg M, Carpaij OA, Polanski K, Simon LM, Brouwer S, Gomes T, Hesse L, Jiang J, Fasouli ES, Efremova M, Vento-Tormo R, Talavera-López C, Jonker MR, Affleck K, Palit S, Strzelecka PM, Firth HV, Mahbubani KT, Cvejic A, Meyer KB, Saeb-Parsy K, Luinge M, Brandsma CA, Timens W, Angelidis I, Strunz M, Koppelman GH, van Oosterhout AJ, Schiller HB, Theis FJ, van den Berge M, Nawijn MC, Teichmann SA.

Nat Med. 2019 Jul;25(7):1153-1163. doi: 10.1038/s41591-019-0468-5. Epub 2019 Jun 17.

PMID:
31209336
2.

The Human Lung Cell Atlas: A High-Resolution Reference Map of the Human Lung in Health and Disease.

Schiller HB, Montoro DT, Simon LM, Rawlins EL, Meyer KB, Strunz M, Vieira Braga FA, Timens W, Koppelman GH, Budinger GRS, Burgess JK, Waghray A, van den Berge M, Theis FJ, Regev A, Kaminski N, Rajagopal J, Teichmann SA, Misharin AV, Nawijn MC.

Am J Respir Cell Mol Biol. 2019 Jul;61(1):31-41. doi: 10.1165/rcmb.2018-0416TR.

PMID:
30995076
3.

An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics.

Angelidis I, Simon LM, Fernandez IE, Strunz M, Mayr CH, Greiffo FR, Tsitsiridis G, Ansari M, Graf E, Strom TM, Nagendran M, Desai T, Eickelberg O, Mann M, Theis FJ, Schiller HB.

Nat Commun. 2019 Feb 27;10(1):963. doi: 10.1038/s41467-019-08831-9.

4.

Development and validation of response markers to predict survival and pleurodesis success in patients with malignant pleural effusion (PROMISE): a multicohort analysis.

Psallidas I, Kanellakis NI, Gerry S, Thézénas ML, Charles PD, Samsonova A, Schiller HB, Fischer R, Asciak R, Hallifax RJ, Mercer R, Dobson M, Dong T, Pavord ID, Collins GS, Kessler BM, Pass HI, Maskell N, Stathopoulos GT, Rahman NM.

Lancet Oncol. 2018 Jul;19(7):930-939. doi: 10.1016/S1470-2045(18)30294-8. Epub 2018 Jun 13.

PMID:
29908990
5.

Biotin-Chasing Assay to Evaluate uPAR Stability and Cleavage on the Surface of Cells.

Leksa V, Schiller HB, Stockinger H.

Methods Mol Biol. 2018;1731:39-47. doi: 10.1007/978-1-4939-7595-2_4.

PMID:
29318541
6.

Compartment-resolved Proteomic Analysis of Mouse Aorta during Atherosclerotic Plaque Formation Reveals Osteoclast-specific Protein Expression.

Wierer M, Prestel M, Schiller HB, Yan G, Schaab C, Azghandi S, Werner J, Kessler T, Malik R, Murgia M, Aherrahrou Z, Schunkert H, Dichgans M, Mann M.

Mol Cell Proteomics. 2018 Feb;17(2):321-334. doi: 10.1074/mcp.RA117.000315. Epub 2017 Dec 4.

7.

Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo.

Lehmann M, Korfei M, Mutze K, Klee S, Skronska-Wasek W, Alsafadi HN, Ota C, Costa R, Schiller HB, Lindner M, Wagner DE, Günther A, Königshoff M.

Eur Respir J. 2017 Aug 3;50(2). pii: 1602367. doi: 10.1183/13993003.02367-2016. Print 2017 Aug.

8.

The instructive extracellular matrix of the lung: basic composition and alterations in chronic lung disease.

Burgstaller G, Oehrle B, Gerckens M, White ES, Schiller HB, Eickelberg O.

Eur Respir J. 2017 Jul 5;50(1). pii: 1601805. doi: 10.1183/13993003.01805-2016. Print 2017 Jul. Review.

9.

Functional proteomics of cellular mechanosensing mechanisms.

Wasik AA, Schiller HB.

Semin Cell Dev Biol. 2017 Nov;71:118-128. doi: 10.1016/j.semcdb.2017.06.019. Epub 2017 Jul 1. Review.

PMID:
28676425
10.

Deep Proteome Profiling Reveals Common Prevalence of MZB1-Positive Plasma B Cells in Human Lung and Skin Fibrosis.

Schiller HB, Mayr CH, Leuschner G, Strunz M, Staab-Weijnitz C, Preisendörfer S, Eckes B, Moinzadeh P, Krieg T, Schwartz DA, Hatz RA, Behr J, Mann M, Eickelberg O.

Am J Respir Crit Care Med. 2017 Nov 15;196(10):1298-1310. doi: 10.1164/rccm.201611-2263OC.

PMID:
28654764
11.

αV-class integrins exert dual roles on α5β1 integrins to strengthen adhesion to fibronectin.

Bharadwaj M, Strohmeyer N, Colo GP, Helenius J, Beerenwinkel N, Schiller HB, Fässler R, Müller DJ.

Nat Commun. 2017 Jan 27;8:14348. doi: 10.1038/ncomms14348.

12.

Glutathione peroxidase 3 localizes to the epithelial lining fluid and the extracellular matrix in interstitial lung disease.

Schamberger AC, Schiller HB, Fernandez IE, Sterclova M, Heinzelmann K, Hennen E, Hatz R, Behr J, Vašáková M, Mann M, Eickelberg O, Staab-Weijnitz CA.

Sci Rep. 2016 Jul 20;6:29952. doi: 10.1038/srep29952.

13.

Association of CD147 and Calcium Exporter PMCA4 Uncouples IL-2 Expression from Early TCR Signaling.

Supper V, Schiller HB, Paster W, Forster F, Boulègue C, Mitulovic G, Leksa V, Ohradanova-Repic A, Machacek C, Schatzlmaier P, Zlabinger GJ, Stockinger H.

J Immunol. 2016 Feb 1;196(3):1387-99. doi: 10.4049/jimmunol.1501889. Epub 2016 Jan 4.

14.

Time- and compartment-resolved proteome profiling of the extracellular niche in lung injury and repair.

Schiller HB, Fernandez IE, Burgstaller G, Schaab C, Scheltema RA, Schwarzmayr T, Strom TM, Eickelberg O, Mann M.

Mol Syst Biol. 2015 Jul 14;11(7):819. doi: 10.15252/msb.20156123.

15.

Structural model of a CRISPR RNA-silencing complex reveals the RNA-target cleavage activity in Cmr4.

Benda C, Ebert J, Scheltema RA, Schiller HB, Baumgärtner M, Bonneau F, Mann M, Conti E.

Mol Cell. 2014 Oct 2;56(1):43-54. doi: 10.1016/j.molcel.2014.09.002.

16.

The late endosomal transporter CD222 directs the spatial distribution and activity of Lck.

Pfisterer K, Forster F, Paster W, Supper V, Ohradanova-Repic A, Eckerstorfer P, Zwirzitz A, Donner C, Boulegue C, Schiller HB, Ondrovičová G, Acuto O, Stockinger H, Leksa V.

J Immunol. 2014 Sep 15;193(6):2718-32. doi: 10.4049/jimmunol.1303349. Epub 2014 Aug 15.

17.

β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments.

Schiller HB, Hermann MR, Polleux J, Vignaud T, Zanivan S, Friedel CC, Sun Z, Raducanu A, Gottschalk KE, Théry M, Mann M, Fässler R.

Nat Cell Biol. 2013 Jun;15(6):625-36. doi: 10.1038/ncb2747. Epub 2013 May 26.

PMID:
23708002
18.

Mechanosensitivity and compositional dynamics of cell-matrix adhesions.

Schiller HB, Fässler R.

EMBO Rep. 2013 Jun;14(6):509-19. doi: 10.1038/embor.2013.49. Epub 2013 May 17. Review.

19.

Dissecting mannose 6-phosphate-insulin-like growth factor 2 receptor complexes that control activation and uptake of plasminogen in cells.

Leksa V, Pfisterer K, Ondrovičová G, Binder B, Lakatošová S, Donner C, Schiller HB, Zwirzitz A, Mrvová K, Pevala V, Kutejová E, Stockinger H.

J Biol Chem. 2012 Jun 29;287(27):22450-62. doi: 10.1074/jbc.M112.339663. Epub 2012 May 21.

20.

Quantitative proteomics of the integrin adhesome show a myosin II-dependent recruitment of LIM domain proteins.

Schiller HB, Friedel CC, Boulegue C, Fässler R.

EMBO Rep. 2011 Mar;12(3):259-66. doi: 10.1038/embor.2011.5. Epub 2011 Feb 11.

21.

Soluble M6P/IGF2R released by TACE controls angiogenesis via blocking plasminogen activation.

Leksa V, Loewe R, Binder B, Schiller HB, Eckerstorfer P, Forster F, Soler-Cardona A, Ondrovicová G, Kutejová E, Steinhuber E, Breuss J, Drach J, Petzelbauer P, Binder BR, Stockinger H.

Circ Res. 2011 Mar 18;108(6):676-85. doi: 10.1161/CIRCRESAHA.110.234732. Epub 2011 Jan 27.

PMID:
21273553
22.

Conformational control of integrin-subtype selectivity in isoDGR peptide motifs: a biological switch.

Frank AO, Otto E, Mas-Moruno C, Schiller HB, Marinelli L, Cosconati S, Bochen A, Vossmeyer D, Zahn G, Stragies R, Novellino E, Kessler H.

Angew Chem Int Ed Engl. 2010 Nov 22;49(48):9278-81. doi: 10.1002/anie.201004363. No abstract available.

PMID:
20957712
23.

The kindlins at a glance.

Karaköse E, Schiller HB, Fässler R.

J Cell Sci. 2010 Jul 15;123(Pt 14):2353-6. doi: 10.1242/jcs.064600. Review. No abstract available.

24.

Proximal human FOXP3 promoter transactivated by NF-kappaB and negatively controlled by feedback loop and SP3.

Eckerstorfer P, Novy M, Burgstaller-Muehlbacher S, Paster W, Schiller HB, Mayer H, Stockinger H.

Mol Immunol. 2010 Jul;47(11-12):2094-102. doi: 10.1016/j.molimm.2010.04.002. Epub 2010 May 11.

25.

Sequential cooperation of CD2 and CD48 in the buildup of the early TCR signalosome.

Muhammad A, Schiller HB, Forster F, Eckerstorfer P, Geyeregger R, Leksa V, Zlabinger GJ, Sibilia M, Sonnleitner A, Paster W, Stockinger H.

J Immunol. 2009 Jun 15;182(12):7672-80. doi: 10.4049/jimmunol.0800691.

26.

Mannose 6-phosphate/insulin-like growth factor 2 receptor limits cell invasion by controlling alphaVbeta3 integrin expression and proteolytic processing of urokinase-type plasminogen activator receptor.

Schiller HB, Szekeres A, Binder BR, Stockinger H, Leksa V.

Mol Biol Cell. 2009 Feb;20(3):745-56. doi: 10.1091/mbc.E08-06-0569. Epub 2008 Nov 26.

27.

LFA-1-mediated leukocyte adhesion regulated by interaction of CD43 with LFA-1 and CD147.

Khunkaewla P, Schiller HB, Paster W, Leksa V, Cermák L, Andera L, Horejsí V, Stockinger H.

Mol Immunol. 2008 Mar;45(6):1703-11. Epub 2007 Nov 9.

PMID:
17996943
28.

TGF-beta-induced apoptosis in endothelial cells mediated by M6P/IGFII-R and mini-plasminogen.

Leksa V, Godar S, Schiller HB, Fuertbauer E, Muhammad A, Slezakova K, Horejsi V, Steinlein P, Weidle UH, Binder BR, Stockinger H.

J Cell Sci. 2005 Oct 1;118(Pt 19):4577-86.

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