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Items: 34


The mammalian CTLH complex is an E3 ubiquitin ligase that targets its subunit muskelin for degradation.

Maitland MER, Onea G, Chiasson CA, Wang X, Ma J, Moor SE, Barber KR, Lajoie GA, Shaw GS, Schild-Poulter C.

Sci Rep. 2019 Jul 8;9(1):9864. doi: 10.1038/s41598-019-46279-5.


Regulation of c-Raf Stability through the CTLH Complex.

McTavish CJ, Bérubé-Janzen W, Wang X, Maitland MER, Salemi LM, Hess DA, Schild-Poulter C.

Int J Mol Sci. 2019 Feb 21;20(4). pii: E934. doi: 10.3390/ijms20040934.


Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

Abbasi S, Schild-Poulter C.

J Proteome Res. 2019 Mar 1;18(3):1064-1077. doi: 10.1021/acs.jproteome.8b00771. Epub 2019 Jan 14.


Inhibition of HDAC6 activity through interaction with RanBPM and its associated CTLH complex.

Salemi LM, Maitland MER, Yefet ER, Schild-Poulter C.

BMC Cancer. 2017 Jul 1;17(1):460. doi: 10.1186/s12885-017-3430-2.


Cell signalling pathway regulation by RanBPM: molecular insights and disease implications.

Salemi LM, Maitland MER, McTavish CJ, Schild-Poulter C.

Open Biol. 2017 Jun;7(6). pii: 170081. doi: 10.1098/rsob.170081. Review.


Biasing genome-editing events toward precise length deletions with an RNA-guided TevCas9 dual nuclease.

Wolfs JM, Hamilton TA, Lant JT, Laforet M, Zhang J, Salemi LM, Gloor GB, Schild-Poulter C, Edgell DR.

Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):14988-14993. doi: 10.1073/pnas.1616343114. Epub 2016 Dec 12.


Ku70 Serine 155 mediates Aurora B inhibition and activation of the DNA damage response.

Fell VL, Walden EA, Hoffer SM, Rogers SR, Aitken AS, Salemi LM, Schild-Poulter C.

Sci Rep. 2016 Nov 16;6:37194. doi: 10.1038/srep37194.


The Ku heterodimer: function in DNA repair and beyond.

Fell VL, Schild-Poulter C.

Mutat Res Rev Mutat Res. 2015 Jan-Mar;763:15-29. doi: 10.1016/j.mrrev.2014.06.002. Epub 2014 Jul 4. Review.


Characterization of RanBPM molecular determinants that control its subcellular localization.

Salemi LM, Loureiro SO, Schild-Poulter C.

PLoS One. 2015 Feb 6;10(2):e0117655. doi: 10.1371/journal.pone.0117655. eCollection 2015.


MegaTevs: single-chain dual nucleases for efficient gene disruption.

Wolfs JM, DaSilva M, Meister SE, Wang X, Schild-Poulter C, Edgell DR.

Nucleic Acids Res. 2014 Jul;42(13):8816-29. doi: 10.1093/nar/gku573. Epub 2014 Jul 10.


Aggresome formation is regulated by RanBPM through an interaction with HDAC6.

Salemi LM, Almawi AW, Lefebvre KJ, Schild-Poulter C.

Biol Open. 2014 May 2;3(6):418-30. doi: 10.1242/bio.20147021.


The I-TevI nuclease and linker domains contribute to the specificity of monomeric TALENs.

Kleinstiver BP, Wang L, Wolfs JM, Kolaczyk T, McDowell B, Wang X, Schild-Poulter C, Bogdanove AJ, Edgell DR.

G3 (Bethesda). 2014 Apr 16;4(6):1155-65. doi: 10.1534/g3.114.011445.


Regulation of stress-inducible phosphoprotein 1 nuclear retention by protein inhibitor of activated STAT PIAS1.

Soares IN, Caetano FA, Pinder J, Rodrigues BR, Beraldo FH, Ostapchenko VG, Durette C, Pereira GS, Lopes MH, Queiroz-Hazarbassanov N, Cunha IW, Sanematsu PI, Suzuki S, Bleggi-Torres LF, Schild-Poulter C, Thibault P, Dellaire G, Martins VR, Prado VF, Prado MA.

Mol Cell Proteomics. 2013 Nov;12(11):3253-70. doi: 10.1074/mcp.M113.031005. Epub 2013 Aug 12.


RanBPM is an inhibitor of ERK signaling.

Atabakhsh E, Schild-Poulter C.

PLoS One. 2012;7(10):e47803. doi: 10.1371/journal.pone.0047803. Epub 2012 Oct 31.


Molecular pathway reconstruction and analysis of disturbed gene expression in depressed individuals who died by suicide.

Zhurov V, Stead JD, Merali Z, Palkovits M, Faludi G, Schild-Poulter C, Anisman H, Poulter MO.

PLoS One. 2012;7(10):e47581. doi: 10.1371/journal.pone.0047581. Epub 2012 Oct 22. Erratum in: PLoS One. 2013;8(2). doi:10.1371/annotation/a023885b-a395-4d6c-9f7c-fe255675f171.


RanBPM expression regulates transcriptional pathways involved in development and tumorigenesis.

Atabakhsh E, Wang JH, Wang X, Carter DE, Schild-Poulter C.

Am J Cancer Res. 2012;2(5):549-65. Epub 2012 Aug 20.


Ku regulates signaling to DNA damage response pathways through the Ku70 von Willebrand A domain.

Fell VL, Schild-Poulter C.

Mol Cell Biol. 2012 Jan;32(1):76-87. doi: 10.1128/MCB.05661-11. Epub 2011 Oct 28.


RanBPM has proapoptotic activities that regulate cell death pathways in response to DNA damage.

Atabakhsh E, Bryce DM, Lefebvre KJ, Schild-Poulter C.

Mol Cancer Res. 2009 Dec;7(12):1962-72. doi: 10.1158/1541-7786.MCR-09-0098. Epub 2009 Dec 8.


Association of autoantibodies with Ku and DNA repair proteins in connective tissue diseases.

Schild-Poulter C, Su A, Shih A, Kelly OP, Fritzler MJ, Goldstein R, Haché RJ.

Rheumatology (Oxford). 2008 Feb;47(2):165-71. doi: 10.1093/rheumatology/kem338.


DNA-PK phosphorylation sites on Oct-1 promote cell survival following DNA damage.

Schild-Poulter C, Shih A, Tantin D, Yarymowich NC, Soubeyrand S, Sharp PA, Haché RJ.

Oncogene. 2007 Jun 7;26(27):3980-8. Epub 2007 Jan 8.


The octamer binding transcription factor Oct-1 is a stress sensor.

Tantin D, Schild-Poulter C, Wang V, Haché RJ, Sharp PA.

Cancer Res. 2005 Dec 1;65(23):10750-8.


Structured DNA promotes phosphorylation of p53 by DNA-dependent protein kinase at serine 9 and threonine 18.

Soubeyrand S, Schild-Poulter C, Haché RJ.

Eur J Biochem. 2004 Sep;271(18):3776-84.


Stimulation of preadipocyte differentiation by steroid through targeting of an HDAC1 complex.

Wiper-Bergeron N, Wu D, Pope L, Schild-Poulter C, Haché RJ.

EMBO J. 2003 May 1;22(9):2135-45.


Differential DNA binding of Ku antigen determines its involvement in DNA replication.

Schild-Poulter C, Matheos D, Novac O, Cui B, Giffin W, Ruiz MT, Price GB, Zannis-Hadjopoulos M, Haché RJ.

DNA Cell Biol. 2003 Feb;22(2):65-78.


Evidence implicating Ku antigen as a structural factor in RNA polymerase II-mediated transcription.

Bertinato J, Tomlinson JJ, Schild-Poulter C, Haché RJ.

Gene. 2003 Jan 2;302(1-2):53-64.


Activation and autoregulation of DNA-PK from structured single-stranded DNA and coding end hairpins.

Soubeyrand S, Torrance H, Giffin W, Gong W, Schild-Poulter C, Haché RJ.

Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9605-10. Epub 2001 Jul 31.


The binding of Ku antigen to homeodomain proteins promotes their phosphorylation by DNA-dependent protein kinase.

Schild-Poulter C, Pope L, Giffin W, Kochan JC, Ngsee JK, Traykova-Andonova M, Haché RJ.

J Biol Chem. 2001 May 18;276(20):16848-56. Epub 2001 Feb 20.


Nuclear localization of Ku antigen is promoted independently by basic motifs in the Ku70 and Ku80 subunits.

Bertinato J, Schild-Poulter C, Haché RJ.

J Cell Sci. 2001 Jan;114(Pt 1):89-99.


Regulation of the vitellogenin gene B1 promoter after transfer into hepatocytes in primary cultures.

Marilley D, Robyr D, Schild-Poulter C, Wahli W.

Mol Cell Endocrinol. 1998 Jun 25;141(1-2):79-93.


Recruitment of octamer transcription factors to DNA by glucocorticoid receptor.

Préfontaine GG, Lemieux ME, Giffin W, Schild-Poulter C, Pope L, LaCasse E, Walker P, Haché RJ.

Mol Cell Biol. 1998 Jun;18(6):3416-30.


Nucleosome assembly on the human c-fos promoter interferes with transcription factor binding.

Schild-Poulter C, Sassone-Corsi P, Granger-Schnarr M, Schnarr M.

Nucleic Acids Res. 1996 Dec 1;24(23):4751-8.


Fate of linear and supercoiled multinucleosomic templates during transcription.

ten Heggeler-Bordier B, Schild-Poulter C, Chapel S, Wahli W.

EMBO J. 1995 Jun 1;14(11):2561-9.

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