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Items: 1 to 50 of 91

1.

Congenital Transmission of Trypanosoma cruzi: A Review About the Interactions Between the Parasite, the Placenta, the Maternal and the Fetal/Neonatal Immune Responses.

Kemmerling U, Osuna A, Schijman AG, Truyens C.

Front Microbiol. 2019 Aug 14;10:1854. doi: 10.3389/fmicb.2019.01854. eCollection 2019. Review.

2.

Role of nucleic acid amplification assays in monitoring treatment response in chagas disease: Usefulness in clinical trials.

Sulleiro E, Muñoz-Calderon A, Schijman AG.

Acta Trop. 2019 Jul 31;199:105120. doi: 10.1016/j.actatropica.2019.105120. [Epub ahead of print] Review.

PMID:
31376368
3.

Detection of anti-Trypanosoma cruzi antibodies by chimeric antigens in chronic Chagas disease-individuals from endemic South American countries.

Del-Rei RP, Leony LM, Celedon PAF, Zanchin NIT, Reis MGD, Gomes YM, Schijman AG, Longhi SA, Santos FLN.

PLoS One. 2019 Apr 18;14(4):e0215623. doi: 10.1371/journal.pone.0215623. eCollection 2019.

4.

Association study between CCR2-CCR5 genes polymorphisms and chronic Chagas heart disease in Wichi and in admixed populations from Argentina.

Juiz NA, Estupiñán E, Hernández D, Garcilazo A, Chadi R, Morales Sanfurgo G, Schijman AG, Longhi SA, González CI.

PLoS Negl Trop Dis. 2019 Jan 16;13(1):e0007033. doi: 10.1371/journal.pntd.0007033. eCollection 2019 Jan.

5.

Usefulness of Serial Blood Sampling and PCR Replicates for Treatment Monitoring of Patients with Chronic Chagas Disease.

Parrado R, Ramirez JC, de la Barra A, Alonso-Vega C, Juiz N, Ortiz L, Illanes D, Torrico F, Gascon J, Alves F, Flevaud L, Garcia L, Schijman AG, Ribeiro I.

Antimicrob Agents Chemother. 2019 Jan 29;63(2). pii: e01191-18. doi: 10.1128/AAC.01191-18. Print 2019 Feb.

6.

The burden of congenital Chagas disease and implementation of molecular diagnostic tools in Latin America.

Picado A, Cruz I, Redard-Jacot M, Schijman AG, Torrico F, Sosa-Estani S, Katz Z, Ndung'u JM.

BMJ Glob Health. 2018 Oct 11;3(5):e001069. doi: 10.1136/bmjgh-2018-001069. eCollection 2018.

7.

Differential infectivity of two Trypanosoma cruzi strains in placental cells and tissue.

Medina L, Castillo C, Liempi A, Herbach M, Cabrera G, Valenzuela L, Galanti N, de Los Angeles Curto M, Schijman AG, Kemmerling U.

Acta Trop. 2018 Oct;186:35-40. doi: 10.1016/j.actatropica.2018.07.001. Epub 2018 Jul 6.

PMID:
30018029
8.

Introducing automation to the molecular diagnosis of Trypanosoma cruzi infection: A comparative study of sample treatments, DNA extraction methods and real-time PCR assays.

Abras A, Ballart C, Llovet T, Roig C, Gutiérrez C, Tebar S, Berenguer P, Pinazo MJ, Posada E, Gascón J, Schijman AG, Gállego M, Muñoz C.

PLoS One. 2018 Apr 17;13(4):e0195738. doi: 10.1371/journal.pone.0195738. eCollection 2018.

9.

Nitric oxide synthase and oxidative-nitrosative stress play a key role in placental infection by Trypanosoma cruzi.

Triquell MF, Díaz-Luján C, Romanini MC, Ramirez JC, Paglini-Oliva P, Schijman AG, Fretes RE.

Am J Reprod Immunol. 2018 Jul;80(1):e12852. doi: 10.1111/aji.12852. Epub 2018 Mar 25.

PMID:
29577492
10.

Alterations in Placental Gene Expression of Pregnant Women with Chronic Chagas Disease.

Juiz NA, Torrejón I, Burgos M, Torres AMF, Duffy T, Cayo NM, Tabasco A, Salvo M, Longhi SA, Schijman AG.

Am J Pathol. 2018 Jun;188(6):1345-1353. doi: 10.1016/j.ajpath.2018.02.011. Epub 2018 Mar 12.

PMID:
29545200
11.

Molecular diagnosis of Trypanosoma cruzi.

Schijman AG.

Acta Trop. 2018 Aug;184:59-66. doi: 10.1016/j.actatropica.2018.02.019. Epub 2018 Feb 21. Review.

PMID:
29476727
12.

New insights into Trypanosoma cruzi evolution, genotyping and molecular diagnostics from satellite DNA sequence analysis.

Ramírez JC, Torres C, Curto MLA, Schijman AG.

PLoS Negl Trop Dis. 2017 Dec 18;11(12):e0006139. doi: 10.1371/journal.pntd.0006139. eCollection 2017 Dec.

13.

First external quality assurance program for bloodstream Real-Time PCR monitoring of treatment response in clinical trials of Chagas disease.

Ramírez JC, Parrado R, Sulleiro E, de la Barra A, Rodríguez M, Villarroel S, Irazu L, Alonso-Vega C, Alves F, Curto MA, García L, Ortiz L, Torrico F, Gascón J, Flevaud L, Molina I, Ribeiro I, Schijman AG.

PLoS One. 2017 Nov 27;12(11):e0188550. doi: 10.1371/journal.pone.0188550. eCollection 2017.

14.

Analytical sensitivity and specificity of a loop-mediated isothermal amplification (LAMP) kit prototype for detection of Trypanosoma cruzi DNA in human blood samples.

Besuschio SA, Llano Murcia M, Benatar AF, Monnerat S, Cruz I, Picado A, Curto MLÁ, Kubota Y, Wehrendt DP, Pavia P, Mori Y, Puerta C, Ndung'u JM, Schijman AG.

PLoS Negl Trop Dis. 2017 Jul 20;11(7):e0005779. doi: 10.1371/journal.pntd.0005779. eCollection 2017 Jul.

15.

Molecular diagnostics for Chagas disease: up to date and novel methodologies.

Alonso-Padilla J, Gallego M, Schijman AG, Gascon J.

Expert Rev Mol Diagn. 2017 Jul;17(7):699-710. doi: 10.1080/14737159.2017.1338566. Epub 2017 Jun 9. Review.

PMID:
28582629
16.

Immune complexes in chronic Chagas disease patients are formed by exovesicles from Trypanosoma cruzi carrying the conserved MASP N-terminal region.

Díaz Lozano IM, De Pablos LM, Longhi SA, Zago MP, Schijman AG, Osuna A.

Sci Rep. 2017 Mar 15;7:44451. doi: 10.1038/srep44451.

17.

Different genotypes of Trypanosoma cruzi produce distinctive placental environment genetic response in chronic experimental infection.

Juiz NA, Solana ME, Acevedo GR, Benatar AF, Ramirez JC, da Costa PA, Macedo AM, Longhi SA, Schijman AG.

PLoS Negl Trop Dis. 2017 Mar 8;11(3):e0005436. doi: 10.1371/journal.pntd.0005436. eCollection 2017 Mar.

18.

Subtelomeric I-SceI-Mediated Double-Strand Breaks Are Repaired by Homologous Recombination in Trypanosoma cruzi.

Chiurillo MA, Moraes Barros RR, Souza RT, Marini MM, Antonio CR, Cortez DR, Curto MÁ, Lorenzi HA, Schijman AG, Ramirez JL, da Silveira JF.

Front Microbiol. 2016 Dec 22;7:2041. doi: 10.3389/fmicb.2016.02041. eCollection 2016.

19.

Identification of Trypanosoma cruzi Discrete Typing Units (DTUs) in Latin-American migrants in Barcelona (Spain).

Abras A, Gállego M, Muñoz C, Juiz NA, Ramírez JC, Cura CI, Tebar S, Fernández-Arévalo A, Pinazo MJ, de la Torre L, Posada E, Navarro F, Espinal P, Ballart C, Portús M, Gascón J, Schijman AG.

Parasitol Int. 2017 Apr;66(2):83-88. doi: 10.1016/j.parint.2016.12.003. Epub 2016 Dec 7.

PMID:
27940065
20.

Molecular characterization of trypanosomatid infections in wild howler monkeys (Alouatta caraya) in northeastern Argentina.

Martínez MF, Kowalewski MM, Salomón OD, Schijman AG.

Int J Parasitol Parasites Wildl. 2016 May 11;5(2):198-206. doi: 10.1016/j.ijppaw.2016.05.001. eCollection 2016 Aug.

21.

The C-terminal region of Trypanosoma cruzi MASPs is antigenic and secreted via exovesicles.

De Pablos LM, Díaz Lozano IM, Jercic MI, Quinzada M, Giménez MJ, Calabuig E, Espino AM, Schijman AG, Zulantay I, Apt W, Osuna A.

Sci Rep. 2016 Jun 8;6:27293. doi: 10.1038/srep27293.

22.

Serological based monitoring of a cohort of patients with chronic Chagas disease treated with benznidazole in a highly endemic area of northern Argentina.

Niborski LL, Grippo V, Lafón SO, Levitus G, García-Bournissen F, Ramirez JC, Burgos JM, Bisio M, Juiz NA, Ayala V, Coppede M, Herrera V, López C, Contreras A, Gómez KA, Elean JC, Mujica HD, Schijman AG, Levin MJ, Longhi SA.

Mem Inst Oswaldo Cruz. 2016 May 24;111(6):365-71. doi: 10.1590/0074-02760160006.

23.

Chagas' disease in Aboriginal and Creole communities from the Gran Chaco Region of Argentina: Seroprevalence and molecular parasitological characterization.

Lucero RH, Brusés BL, Cura CI, Formichelli LB, Juiz N, Fernández GJ, Bisio M, Deluca GD, Besuschio S, Hernández DO, Schijman AG.

Infect Genet Evol. 2016 Jul;41:84-92. doi: 10.1016/j.meegid.2016.03.028. Epub 2016 Apr 4.

PMID:
27057620
24.

Pharmacokinetic and pharmacodynamic responses in adult patients with Chagas disease treated with a new formulation of benznidazole.

Fernández ML, Marson ME, Ramirez JC, Mastrantonio G, Schijman AG, Altcheh J, Riarte AR, Bournissen FG.

Mem Inst Oswaldo Cruz. 2016 Mar;111(3):218-21. doi: 10.1590/0074-02760150401. Epub 2016 Mar 15.

25.

Human Polymorphisms in Placentally Expressed Genes and Their Association With Susceptibility to Congenital Trypanosoma cruzi Infection.

Juiz NA, Cayo NM, Burgos M, Salvo ME, Nasser JR, Búa J, Longhi SA, Schijman AG.

J Infect Dis. 2016 Apr 15;213(8):1299-306. doi: 10.1093/infdis/jiv561. Epub 2015 Nov 23.

PMID:
26597259
26.

Analytical Validation of Quantitative Real-Time PCR Methods for Quantification of Trypanosoma cruzi DNA in Blood Samples from Chagas Disease Patients.

Ramírez JC, Cura CI, da Cruz Moreira O, Lages-Silva E, Juiz N, Velázquez E, Ramírez JD, Alberti A, Pavia P, Flores-Chávez MD, Muñoz-Calderón A, Pérez-Morales D, Santalla J, Marcos da Matta Guedes P, Peneau J, Marcet P, Padilla C, Cruz-Robles D, Valencia E, Crisante GE, Greif G, Zulantay I, Costales JA, Alvarez-Martínez M, Martínez NE, Villarroel R, Villarroel S, Sánchez Z, Bisio M, Parrado R, Maria da Cunha Galvão L, Jácome da Câmara AC, Espinoza B, Alarcón de Noya B, Puerta C, Riarte A, Diosque P, Sosa-Estani S, Guhl F, Ribeiro I, Aznar C, Britto C, Yadón ZE, Schijman AG.

J Mol Diagn. 2015 Sep;17(5):605-15. doi: 10.1016/j.jmoldx.2015.04.010.

27.

A flow cytometer-based method to simultaneously assess activity and selectivity of compounds against the intracellular forms of Trypanosoma cruzi.

Miranda CG, Solana ME, Curto MLA, Lammel EM, Schijman AG, Alba Soto CD.

Acta Trop. 2015 Dec;152:8-16. doi: 10.1016/j.actatropica.2015.08.004. Epub 2015 Aug 10.

PMID:
26272680
28.

Target Product Profile (TPP) for Chagas Disease Point-of-Care Diagnosis and Assessment of Response to Treatment.

Porrás AI, Yadon ZE, Altcheh J, Britto C, Chaves GC, Flevaud L, Martins-Filho OA, Ribeiro I, Schijman AG, Shikanai-Yasuda MA, Sosa-Estani S, Stobbaerts E, Zicker F.

PLoS Negl Trop Dis. 2015 Jun 4;9(6):e0003697. doi: 10.1371/journal.pntd.0003697. eCollection 2015 Jun. No abstract available.

29.

Multiplex Real-Time PCR Assay Using TaqMan Probes for the Identification of Trypanosoma cruzi DTUs in Biological and Clinical Samples.

Cura CI, Duffy T, Lucero RH, Bisio M, Péneau J, Jimenez-Coello M, Calabuig E, Gimenez MJ, Valencia Ayala E, Kjos SA, Santalla J, Mahaney SM, Cayo NM, Nagel C, Barcán L, Málaga Machaca ES, Acosta Viana KY, Brutus L, Ocampo SB, Aznar C, Cuba Cuba CA, Gürtler RE, Ramsey JM, Ribeiro I, VandeBerg JL, Yadon ZE, Osuna A, Schijman AG.

PLoS Negl Trop Dis. 2015 May 19;9(5):e0003765. doi: 10.1371/journal.pntd.0003765. eCollection 2015 May.

30.

First report of a family outbreak of Chagas disease in French Guiana and posttreatment follow-up.

Blanchet D, Brenière SF, Schijman AG, Bisio M, Simon S, Véron V, Mayence C, Demar-Pierre M, Djossou F, Aznar C.

Infect Genet Evol. 2014 Dec;28:245-50. doi: 10.1016/j.meegid.2014.10.004. Epub 2014 Oct 14.

PMID:
25448161
31.

Drug discovery for Chagas disease should consider Trypanosoma cruzi strain diversity.

Zingales B, Miles MA, Moraes CB, Luquetti A, Guhl F, Schijman AG, Ribeiro I; Drugs for Neglected Disease Initiative; Chagas Clinical Research Platform Meeting.

Mem Inst Oswaldo Cruz. 2014 Sep;109(6):828-33. Epub 2014 Aug 22.

32.

Geographic variation of Trypanosoma cruzi discrete typing units from Triatoma infestans at different spatial scales.

Fernández Mdel P, Cecere MC, Lanati LA, Lauricella MA, Schijman AG, Gürtler RE, Cardinal MV.

Acta Trop. 2014 Dec;140:10-8. doi: 10.1016/j.actatropica.2014.07.014. Epub 2014 Aug 1.

PMID:
25090650
33.

Cloning and expression of transgenes using linear vectors in Trypanosoma cruzi.

Curto Mde L, Lorenzi HA, Moraes Barros RR, Souza RT, Levin MJ, Da Silveira JF, Schijman AG.

Int J Parasitol. 2014 Jun;44(7):447-56. doi: 10.1016/j.ijpara.2014.03.009. Epub 2014 Apr 20.

PMID:
24759431
34.

High levels of Trypanosoma cruzi DNA determined by qPCR and infectiousness to Triatoma infestans support dogs and cats are major sources of parasites for domestic transmission.

Enriquez GF, Bua J, Orozco MM, Wirth S, Schijman AG, Gürtler RE, Cardinal MV.

Infect Genet Evol. 2014 Jul;25:36-43. doi: 10.1016/j.meegid.2014.04.002. Epub 2014 Apr 13.

PMID:
24732410
35.

Biological markers for evaluating therapeutic efficacy in Chagas disease, a systematic review.

Pinazo MJ, Thomas MC, Bua J, Perrone A, Schijman AG, Viotti RJ, Ramsey JM, Ribeiro I, Sosa-Estani S, López MC, Gascon J.

Expert Rev Anti Infect Ther. 2014 Apr;12(4):479-96. doi: 10.1586/14787210.2014.899150. Review.

PMID:
24621252
36.

Early molecular diagnosis of acute Chagas disease after transplantation with organs from Trypanosoma cruzi-infected donors.

Cura CI, Lattes R, Nagel C, Gimenez MJ, Blanes M, Calabuig E, Iranzo A, Barcan LA, Anders M, Schijman AG.

Am J Transplant. 2013 Dec;13(12):3253-61. doi: 10.1111/ajt.12487. Epub 2013 Oct 30.

37.

Towards a paradigm shift in the treatment of chronic Chagas disease.

Viotti R, Alarcón de Noya B, Araujo-Jorge T, Grijalva MJ, Guhl F, López MC, Ramsey JM, Ribeiro I, Schijman AG, Sosa-Estani S, Torrico F, Gascon J; Latin American Network for Chagas Disease, NHEPACHA.

Antimicrob Agents Chemother. 2014;58(2):635-9. doi: 10.1128/AAC.01662-13. Epub 2013 Nov 18.

38.

Benznidazole treatment of chagasic encephalitis in pregnant woman with AIDS.

Bisio M, Altcheh J, Lattner J, Moscatelli G, Fink V, Burgos JM, Bournissen FG, Schijman AG, Freilij H.

Emerg Infect Dis. 2013;19(9):1490-2. doi: 10.3201/eid1909.130667.

39.

Evaluation of nifurtimox treatment of chronic Chagas disease by means of several parasitological methods.

Muñoz C, Zulantay I, Apt W, Ortiz S, Schijman AG, Bisio M, Ferrada V, Herrera C, Martínez G, Solari A.

Antimicrob Agents Chemother. 2013 Sep;57(9):4518-23. doi: 10.1128/AAC.00227-13. Epub 2013 Jul 8.

40.

Impairment in natural killer cells editing of immature dendritic cells by infection with a virulent Trypanosoma cruzi population.

Batalla EI, Pino Martínez AM, Poncini CV, Duffy T, Schijman AG, González Cappa SM, Alba Soto CD.

J Innate Immun. 2013;5(5):494-504. doi: 10.1159/000350242. Epub 2013 May 8.

41.

New sylvatic hosts of Trypanosoma cruzi and their reservoir competence in the humid Chaco of Argentina: a longitudinal study.

Orozco MM, Enriquez GF, Alvarado-Otegui JA, Cardinal MV, Schijman AG, Kitron U, Gürtler RE.

Am J Trop Med Hyg. 2013 May;88(5):872-82. doi: 10.4269/ajtmh.12-0519. Epub 2013 Mar 25.

42.

Detection of Trypanosoma cruzi infection in naturally infected dogs and cats using serological, parasitological and molecular methods.

Enriquez GF, Cardinal MV, Orozco MM, Schijman AG, Gürtler RE.

Acta Trop. 2013 Jun;126(3):211-7. doi: 10.1016/j.actatropica.2013.03.001. Epub 2013 Mar 13.

43.

Analytical performance of a multiplex Real-Time PCR assay using TaqMan probes for quantification of Trypanosoma cruzi satellite DNA in blood samples.

Duffy T, Cura CI, Ramirez JC, Abate T, Cayo NM, Parrado R, Bello ZD, Velazquez E, Muñoz-Calderon A, Juiz NA, Basile J, Garcia L, Riarte A, Nasser JR, Ocampo SB, Yadon ZE, Torrico F, de Noya BA, Ribeiro I, Schijman AG.

PLoS Negl Trop Dis. 2013;7(1):e2000. doi: 10.1371/journal.pntd.0002000. Epub 2013 Jan 17.

44.

Discrete typing units of Trypanosoma cruzi identified in rural dogs and cats in the humid Argentinean Chaco.

Enriquez GF, Cardinal MV, Orozco MM, Lanati L, Schijman AG, Gürtler RE.

Parasitology. 2013 Mar;140(3):303-8. doi: 10.1017/S003118201200159X. Epub 2012 Oct 12.

45.

Direct molecular identification of Trypanosoma cruzi discrete typing units in domestic and peridomestic Triatoma infestans and Triatoma sordida from the Argentine Chaco.

Maffey L, Cardinal MV, Ordóñez-Krasnowski PC, Lanati LA, Lauricella MA, Schijman AG, Gürtler RE.

Parasitology. 2012 Oct;139(12):1570-9. doi: 10.1017/S0031182012000856. Epub 2012 Jul 19.

46.

Evaluation of in-house ELISA using Trypanosoma cruzi lysate and recombinant antigens for diagnosis of Chagas disease and discrimination of its clinical forms.

Longhi SA, Brandariz SB, Lafon SO, Niborski LL, Luquetti AO, Schijman AG, Levin MJ, Gómez KA.

Am J Trop Med Hyg. 2012 Aug;87(2):267-71. doi: 10.4269/ajtmh.2012.11-0533.

47.

Sensitive and specific detection of Trypanosoma cruzi DNA in clinical specimens using a multi-target real-time PCR approach.

Qvarnstrom Y, Schijman AG, Veron V, Aznar C, Steurer F, da Silva AJ.

PLoS Negl Trop Dis. 2012;6(7):e1689. doi: 10.1371/journal.pntd.0001689. Epub 2012 Jul 3.

48.

The sylvatic transmission cycle of Trypanosoma cruzi in a rural area in the humid Chaco of Argentina.

Alvarado-Otegui JA, Ceballos LA, Orozco MM, Enriquez GF, Cardinal MV, Cura C, Schijman AG, Kitron U, Gürtler RE.

Acta Trop. 2012 Oct;124(1):79-86. doi: 10.1016/j.actatropica.2012.06.010. Epub 2012 Jul 3.

49.

Association of Bartonella spp bacteremia with Chagas cardiomyopathy, endocarditis and arrhythmias in patients from South America.

Corrêa FG, Pontes CL, Verzola RM, Mateos JC, Velho PE, Schijman AG, Selistre-de-Araujo HS.

Braz J Med Biol Res. 2012 Jul;45(7):644-51. Epub 2012 May 17.

50.

Trypanosoma cruzi discrete typing units in Chagas disease patients from endemic and non-endemic regions of Argentina.

Cura CI, Lucero RH, Bisio M, Oshiro E, Formichelli LB, Burgos JM, Lejona S, Brusés BL, Hernández DO, Severini GV, Velazquez E, Duffy T, Anchart E, Lattes R, Altcheh J, Freilij H, Diez M, Nagel C, Vigliano C, Favaloro L, Favaloro RR, Merino DE, Sosa-Estani S, Schijman AG.

Parasitology. 2012 Apr;139(4):516-21. doi: 10.1017/S0031182011002186. Epub 2012 Feb 6.

PMID:
22309735

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