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Items: 26

1.

II. In vitro evidence that (-)-OSU6162 and (+)-OSU6162 produce their behavioral effects through 5-HT2A serotonin and D2 dopamine receptors.

Burstein ES, Carlsson ML, Owens M, Ma JN, Schiffer HH, Carlsson A, Hacksell U.

J Neural Transm (Vienna). 2011 Nov;118(11):1523-33. doi: 10.1007/s00702-011-0701-y. Epub 2011 Aug 25.

PMID:
21866391
2.

Differential regulation of muscarinic M1 receptors by orthosteric and allosteric ligands.

Davis CN, Bradley SR, Schiffer HH, Friberg M, Koch K, Tolf BR, Bonhaus DW, Lameh J.

BMC Pharmacol. 2009 Dec 2;9:14. doi: 10.1186/1471-2210-9-14.

3.

AC-260584, an orally bioavailable M(1) muscarinic receptor allosteric agonist, improves cognitive performance in an animal model.

Bradley SR, Lameh J, Ohrmund L, Son T, Bajpai A, Nguyen D, Friberg M, Burstein ES, Spalding TA, Ott TR, Schiffer HH, Tabatabaei A, McFarland K, Davis RE, Bonhaus DW.

Neuropharmacology. 2010 Feb;58(2):365-73. doi: 10.1016/j.neuropharm.2009.10.003. Epub 2009 Oct 14.

PMID:
19835892
4.

Identification and characterization of novel small-molecule protease-activated receptor 2 agonists.

Gardell LR, Ma JN, Seitzberg JG, Knapp AE, Schiffer HH, Tabatabaei A, Davis CN, Owens M, Clemons B, Wong KK, Lund B, Nash NR, Gao Y, Lameh J, Schmelzer K, Olsson R, Burstein ES.

J Pharmacol Exp Ther. 2008 Dec;327(3):799-808. doi: 10.1124/jpet.108.142570. Epub 2008 Sep 3.

PMID:
18768780
5.

The human angiotensin AT(1) receptor supports G protein-independent extracellular signal-regulated kinase 1/2 activation and cellular proliferation.

Hansen JL, Aplin M, Hansen JT, Christensen GL, Bonde MM, Schneider M, Haunsø S, Schiffer HH, Burstein ES, Weiner DM, Sheikh SP.

Eur J Pharmacol. 2008 Aug 20;590(1-3):255-63. doi: 10.1016/j.ejphar.2008.05.010. Epub 2008 May 20.

PMID:
18565507
6.

Broad modulation of neuropathic pain states by a selective estrogen receptor beta agonist.

Piu F, Cheevers C, Hyldtoft L, Gardell LR, Del Tredici AL, Andersen CB, Fairbairn LC, Lund BW, Gustafsson M, Schiffer HH, Donello JE, Olsson R, Gil DW, Brann MR.

Eur J Pharmacol. 2008 Aug 20;590(1-3):423-9. doi: 10.1016/j.ejphar.2008.05.015. Epub 2008 May 23.

PMID:
18559275
7.

Pharmacological characterization of AC-262536, a novel selective androgen receptor modulator.

Piu F, Gardell LR, Son T, Schlienger N, Lund BW, Schiffer HH, Vanover KE, Davis RE, Olsson R, Bradley SR.

J Steroid Biochem Mol Biol. 2008 Mar;109(1-2):129-37. doi: 10.1016/j.jsbmb.2007.11.001. Epub 2007 Nov 22.

PMID:
18164613
8.

Monitoring interactions between receptor tyrosine kinases and their downstream effector proteins in living cells using bioluminescence resonance energy transfer.

Tan PK, Wang J, Littler PL, Wong KK, Sweetnam TA, Keefe W, Nash NR, Reding EC, Piu F, Brann MR, Schiffer HH.

Mol Pharmacol. 2007 Dec;72(6):1440-6. Epub 2007 Aug 22.

PMID:
17715395
9.

Identification of the atypical L-type Ca2+ channel blocker diltiazem and its metabolites as ghrelin receptor agonists.

Ma JN, Schiffer HH, Knapp AE, Wang J, Wong KK, Currier EA, Owens M, Nash NR, Gardell LR, Brann MR, Olsson R, Burstein ES.

Mol Pharmacol. 2007 Aug;72(2):380-6. Epub 2007 May 2.

PMID:
17475811
10.

Pharmacology and signaling properties of epidermal growth factor receptor isoforms studied by bioluminescence resonance energy transfer.

Schiffer HH, Reding EC, Fuhs SR, Lu Q, Piu F, Wong S, Littler PL, Weiner DM, Keefe W, Tan PK, Nash NR, Knapp AE, Olsson R, Brann MR.

Mol Pharmacol. 2007 Feb;71(2):508-18. Epub 2006 Sep 12.

PMID:
16968809
11.

Association of the human kainate receptor GluR7 gene (GRIK3) with recurrent major depressive disorder.

Schiffer HH, Heinemann SF.

Am J Med Genet B Neuropsychiatr Genet. 2007 Jan 5;144B(1):20-6.

PMID:
16958029
12.

Integrative functional assays, chemical genomics and high throughput screening: harnessing signal transduction pathways to a common HTS readout.

Burstein ES, Piu F, Ma JN, Weissman JT, Currier EA, Nash NR, Weiner DM, Spalding TA, Schiffer HH, Del Tredici AL, Brann MR.

Curr Pharm Des. 2006;12(14):1717-29.

PMID:
16712484
13.

Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist.

Vanover KE, Weiner DM, Makhay M, Veinbergs I, Gardell LR, Lameh J, Del Tredici AL, Piu F, Schiffer HH, Ott TR, Burstein ES, Uldam AK, Thygesen MB, Schlienger N, Andersson CM, Son TY, Harvey SC, Powell SB, Geyer MA, Tolf BR, Brann MR, Davis RE.

J Pharmacol Exp Ther. 2006 May;317(2):910-8. Epub 2006 Feb 9.

PMID:
16469866
14.

Characterization of the Mas-related gene family: structural and functional conservation of human and rhesus MrgX receptors.

Burstein ES, Ott TR, Feddock M, Ma JN, Fuhs S, Wong S, Schiffer HH, Brann MR, Nash NR.

Br J Pharmacol. 2006 Jan;147(1):73-82.

15.

Pharmacology of polymorphic variants of the human 5-HT1A receptor.

Del Tredici AL, Schiffer HH, Burstein ES, Lameh J, Mohell N, Hacksell U, Brann MR, Weiner DM.

Biochem Pharmacol. 2004 Feb 1;67(3):479-90.

PMID:
15037200
16.

Distribution analysis of nonsynonymous polymorphisms within the G-protein-coupled receptor gene family.

Lee A, Rana BK, Schiffer HH, Schork NJ, Brann MR, Insel PA, Weiner DM.

Genomics. 2003 Mar;81(3):245-8.

PMID:
12659808
17.

Glutamate receptor genes: susceptibility factors in schizophrenia and depressive disorders?

Schiffer HH.

Mol Neurobiol. 2002 Apr;25(2):191-212. Review.

PMID:
11936559
18.

The role of RNA editing of kainate receptors in synaptic plasticity and seizures.

Vissel B, Royle GA, Christie BR, Schiffer HH, Ghetti A, Tritto T, Perez-Otano I, Radcliffe RA, Seamans J, Sejnowski T, Wehner JM, Collins AC, O'Gorman S, Heinemann SF.

Neuron. 2001 Jan;29(1):217-27.

19.

Unequal expression of allelic kainate receptor GluR7 mRNAs in human brains.

Schiffer HH, Swanson GT, Masliah E, Heinemann SF.

J Neurosci. 2000 Dec 15;20(24):9025-33.

20.

A quantitative method to detect RNA editing events.

Schiffer HH, Heinemann SF.

Anal Biochem. 1999 Dec 15;276(2):257-60. No abstract available.

PMID:
10603250
21.

Generation and analysis of GluR5(Q636R) kainate receptor mutant mice.

Sailer A, Swanson GT, Pérez-Otaño I, O'Leary L, Malkmus SA, Dyck RH, Dickinson-Anson H, Schiffer HH, Maron C, Yaksh TL, Gage FH, O'Gorman S, Heinemann SF.

J Neurosci. 1999 Oct 15;19(20):8757-64.

23.

Vacuolar/lysosomal proteolysis: proteases, substrates, mechanisms.

Knop M, Schiffer HH, Rupp S, Wolf DH.

Curr Opin Cell Biol. 1993 Dec;5(6):990-6. Review.

PMID:
8129953
26.

Lysosomal and non-lysosomal proteolysis in the eukaryotic cell: studies on yeast.

Heinemeyer W, Simeon A, Hirsch HH, Schiffer HH, Teichert U, Wolf DH.

Biochem Soc Trans. 1991 Aug;19(3):724-5. Review. No abstract available.

PMID:
1783206

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