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Items: 1 to 50 of 175

1.

Biofabrication of Cell-Derived Nanovesicles: A Potential Alternative to Extracellular Vesicles for Regenerative Medicine.

Ilahibaks NF, Lei Z, Mol EA, Deshantri AK, Jiang L, Schiffelers RM, Vader P, Sluijter JPG.

Cells. 2019 Nov 25;8(12). pii: E1509. doi: 10.3390/cells8121509.

2.

Bacterial membrane vesicles as promising vaccine candidates.

Jiang L, Schinkel M, van Essen M, Schiffelers RM.

Eur J Pharm Biopharm. 2019 Dec;145:1-6. doi: 10.1016/j.ejpb.2019.09.021. Epub 2019 Sep 24. Review.

PMID:
31560955
3.

A head-to-head comparison of conjugation methods for VHHs: Random maleimide-thiol coupling versus controlled click chemistry.

van Moorsel MVA, Urbanus RT, Verhoef S, Koekman CA, Vink M, Vermonden T, Maas C, Pasterkamp G, Schiffelers RM.

Int J Pharm X. 2019 Jun 21;1:100020. doi: 10.1016/j.ijpx.2019.100020. eCollection 2019 Dec.

4.

Development and characterization of liposomal formulation of bortezomib.

Deshantri AK, Metselaar JM, Zagkou S, Storm G, Mandhane SN, Fens MHAM, Schiffelers RM.

Int J Pharm X. 2019 Mar 23;1:100011. doi: 10.1016/j.ijpx.2019.100011. eCollection 2019 Dec.

5.

Tumor Seeding During Colonoscopy as a Possible Cause for Metachronous Colorectal Cancer.

Backes Y, Seerden TCJ, van Gestel RSFE, Kranenburg O, Ubink I, Schiffelers RM, van Straten D, van der Capellen MS, van de Weerd S, de Leng WWJ, Siersema PD, Offerhaus GJA, Morsink FH, Ramphal W, Terhaar Sive Droste J, van Lent AUG, Geesing JMJ, Vleggaar FP, Elias SG, Lacle MM, Moons LMG.

Gastroenterology. 2019 Nov;157(5):1222-1232.e4. doi: 10.1053/j.gastro.2019.07.062. Epub 2019 Aug 13.

PMID:
31419435
6.

Red Blood Cells: Chasing Interactions.

Pretini V, Koenen MH, Kaestner L, Fens MHAM, Schiffelers RM, Bartels M, Van Wijk R.

Front Physiol. 2019 Jul 31;10:945. doi: 10.3389/fphys.2019.00945. eCollection 2019. Review.

7.

Drug Delivery with Extracellular Vesicles: From Imagination to Innovation.

de Jong OG, Kooijmans SAA, Murphy DE, Jiang L, Evers MJW, Sluijter JPG, Vader P, Schiffelers RM.

Acc Chem Res. 2019 Jul 16;52(7):1761-1770. doi: 10.1021/acs.accounts.9b00109. Epub 2019 Jun 5.

8.

Interfering with endolysosomal trafficking enhances release of bioactive exosomes.

Ortega FG, Roefs MT, de Miguel Perez D, Kooijmans SA, de Jong OG, Sluijter JP, Schiffelers RM, Vader P.

Nanomedicine. 2019 Aug;20:102014. doi: 10.1016/j.nano.2019.102014. Epub 2019 May 30.

9.

Density, heterogeneity and deformability of red cells as markers of clinical severity in hereditary spherocytosis.

Huisjes R, Makhro A, Llaudet-Planas E, Hertz L, Petkova-Kirova P, Verhagen LP, Pignatelli S, Rab MA, Schiffelers RM, Seiler E, van Solinge WW, Vives Corrons JL, Mañú-Pereira M, Kaestner L, Bogdanova A, van Wijk R.

Haematologica. 2019 May 30. pii: haematol.2018.188151. doi: 10.3324/haematol.2018.188151. [Epub ahead of print]

10.

Anti-Inflammatory Properties of Plant Derived Natural Products - A Systematic Review.

Allijn IE, Brinkhuis RP, Storm G, Schiffelers RM.

Curr Med Chem. 2019;26(24):4506-4536. doi: 10.2174/0929867325666190523123357.

PMID:
31119997
11.

3D Bioprinting: from Benches to Translational Applications.

Heinrich MA, Liu W, Jimenez A, Yang J, Akpek A, Liu X, Pi Q, Mu X, Hu N, Schiffelers RM, Prakash J, Xie J, Zhang YS.

Small. 2019 Jun;15(23):e1805510. doi: 10.1002/smll.201805510. Epub 2019 Apr 29. Review.

PMID:
31033203
12.

Routine Blood Tests Do Not Predict Survival in Patients with Glioblastoma-Multivariable Analysis of 497 Patients.

Maas SLN, Draaisma K, Snijders TJ, Senders JT, Berendsen S, Seute T, Schiffelers RM, van Solinge WW, Ten Berg MJ, Robe PA, Broekman MLD.

World Neurosurg. 2019 Jun;126:e1081-e1091. doi: 10.1016/j.wneu.2019.03.053. Epub 2019 Mar 14.

PMID:
30880204
13.

Extracellular vesicle-based therapeutics: natural versus engineered targeting and trafficking.

Murphy DE, de Jong OG, Brouwer M, Wood MJ, Lavieu G, Schiffelers RM, Vader P.

Exp Mol Med. 2019 Mar 15;51(3):32. doi: 10.1038/s12276-019-0223-5. Review.

14.

Liposomes with asymmetric bilayers produced from inverse emulsions for nucleic acid delivery.

de Matos MBC, Miranda BS, Rizky Nuari Y, Storm G, Leneweit G, Schiffelers RM, Kok RJ.

J Drug Target. 2019 Jun - Jul;27(5-6):681-689. doi: 10.1080/1061186X.2019.1579819. Epub 2019 Feb 27.

PMID:
30744482
15.

Liposomal dexamethasone inhibits tumor growth in an advanced human-mouse hybrid model of multiple myeloma.

Deshantri AK, Fens MH, Ruiter RWJ, Metselaar JM, Storm G, van Bloois L, Varela-Moreira A, Mandhane SN, Mutis T, Martens ACM, Groen RWJ, Schiffelers RM.

J Control Release. 2019 Feb 28;296:232-240. doi: 10.1016/j.jconrel.2019.01.028. Epub 2019 Jan 22.

PMID:
30682443
16.

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.

Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer NN, Baxter AA, Bebawy M, Beckham C, Bedina Zavec A, Benmoussa A, Berardi AC, Bergese P, Bielska E, Blenkiron C, Bobis-Wozowicz S, Boilard E, Boireau W, Bongiovanni A, Borràs FE, Bosch S, Boulanger CM, Breakefield X, Breglio AM, Brennan MÁ, Brigstock DR, Brisson A, Broekman ML, Bromberg JF, Bryl-Górecka P, Buch S, Buck AH, Burger D, Busatto S, Buschmann D, Bussolati B, Buzás EI, Byrd JB, Camussi G, Carter DR, Caruso S, Chamley LW, Chang YT, Chen C, Chen S, Cheng L, Chin AR, Clayton A, Clerici SP, Cocks A, Cocucci E, Coffey RJ, Cordeiro-da-Silva A, Couch Y, Coumans FA, Coyle B, Crescitelli R, Criado MF, D'Souza-Schorey C, Das S, Datta Chaudhuri A, de Candia P, De Santana EF, De Wever O, Del Portillo HA, Demaret T, Deville S, Devitt A, Dhondt B, Di Vizio D, Dieterich LC, Dolo V, Dominguez Rubio AP, Dominici M, Dourado MR, Driedonks TA, Duarte FV, Duncan HM, Eichenberger RM, Ekström K, El Andaloussi S, Elie-Caille C, Erdbrügger U, Falcón-Pérez JM, Fatima F, Fish JE, Flores-Bellver M, Försönits A, Frelet-Barrand A, Fricke F, Fuhrmann G, Gabrielsson S, Gámez-Valero A, Gardiner C, Gärtner K, Gaudin R, Gho YS, Giebel B, Gilbert C, Gimona M, Giusti I, Goberdhan DC, Görgens A, Gorski SM, Greening DW, Gross JC, Gualerzi A, Gupta GN, Gustafson D, Handberg A, Haraszti RA, Harrison P, Hegyesi H, Hendrix A, Hill AF, Hochberg FH, Hoffmann KF, Holder B, Holthofer H, Hosseinkhani B, Hu G, Huang Y, Huber V, Hunt S, Ibrahim AG, Ikezu T, Inal JM, Isin M, Ivanova A, Jackson HK, Jacobsen S, Jay SM, Jayachandran M, Jenster G, Jiang L, Johnson SM, Jones JC, Jong A, Jovanovic-Talisman T, Jung S, Kalluri R, Kano SI, Kaur S, Kawamura Y, Keller ET, Khamari D, Khomyakova E, Khvorova A, Kierulf P, Kim KP, Kislinger T, Klingeborn M, Klinke DJ 2nd, Kornek M, Kosanović MM, Kovács ÁF, Krämer-Albers EM, Krasemann S, Krause M, Kurochkin IV, Kusuma GD, Kuypers S, Laitinen S, Langevin SM, Languino LR, Lannigan J, Lässer C, Laurent LC, Lavieu G, Lázaro-Ibáñez E, Le Lay S, Lee MS, Lee YXF, Lemos DS, Lenassi M, Leszczynska A, Li IT, Liao K, Libregts SF, Ligeti E, Lim R, Lim SK, Linē A, Linnemannstöns K, Llorente A, Lombard CA, Lorenowicz MJ, Lörincz ÁM, Lötvall J, Lovett J, Lowry MC, Loyer X, Lu Q, Lukomska B, Lunavat TR, Maas SL, Malhi H, Marcilla A, Mariani J, Mariscal J, Martens-Uzunova ES, Martin-Jaular L, Martinez MC, Martins VR, Mathieu M, Mathivanan S, Maugeri M, McGinnis LK, McVey MJ, Meckes DG Jr, Meehan KL, Mertens I, Minciacchi VR, Möller A, Møller Jørgensen M, Morales-Kastresana A, Morhayim J, Mullier F, Muraca M, Musante L, Mussack V, Muth DC, Myburgh KH, Najrana T, Nawaz M, Nazarenko I, Nejsum P, Neri C, Neri T, Nieuwland R, Nimrichter L, Nolan JP, Nolte-'t Hoen EN, Noren Hooten N, O'Driscoll L, O'Grady T, O'Loghlen A, Ochiya T, Olivier M, Ortiz A, Ortiz LA, Osteikoetxea X, Østergaard O, Ostrowski M, Park J, Pegtel DM, Peinado H, Perut F, Pfaffl MW, Phinney DG, Pieters BC, Pink RC, Pisetsky DS, Pogge von Strandmann E, Polakovicova I, Poon IK, Powell BH, Prada I, Pulliam L, Quesenberry P, Radeghieri A, Raffai RL, Raimondo S, Rak J, Ramirez MI, Raposo G, Rayyan MS, Regev-Rudzki N, Ricklefs FL, Robbins PD, Roberts DD, Rodrigues SC, Rohde E, Rome S, Rouschop KM, Rughetti A, Russell AE, Saá P, Sahoo S, Salas-Huenuleo E, Sánchez C, Saugstad JA, Saul MJ, Schiffelers RM, Schneider R, Schøyen TH, Scott A, Shahaj E, Sharma S, Shatnyeva O, Shekari F, Shelke GV, Shetty AK, Shiba K, Siljander PR, Silva AM, Skowronek A, Snyder OL 2nd, Soares RP, Sódar BW, Soekmadji C, Sotillo J, Stahl PD, Stoorvogel W, Stott SL, Strasser EF, Swift S, Tahara H, Tewari M, Timms K, Tiwari S, Tixeira R, Tkach M, Toh WS, Tomasini R, Torrecilhas AC, Tosar JP, Toxavidis V, Urbanelli L, Vader P, van Balkom BW, van der Grein SG, Van Deun J, van Herwijnen MJ, Van Keuren-Jensen K, van Niel G, van Royen ME, van Wijnen AJ, Vasconcelos MH, Vechetti IJ Jr, Veit TD, Vella LJ, Velot É, Verweij FJ, Vestad B, Viñas JL, Visnovitz T, Vukman KV, Wahlgren J, Watson DC, Wauben MH, Weaver A, Webber JP, Weber V, Wehman AM, Weiss DJ, Welsh JA, Wendt S, Wheelock AM, Wiener Z, Witte L, Wolfram J, Xagorari A, Xander P, Xu J, Yan X, Yáñez-Mó M, Yin H, Yuana Y, Zappulli V, Zarubova J, Žėkas V, Zhang JY, Zhao Z, Zheng L, Zheutlin AR, Zickler AM, Zimmermann P, Zivkovic AM, Zocco D, Zuba-Surma EK.

J Extracell Vesicles. 2018 Nov 23;7(1):1535750. doi: 10.1080/20013078.2018.1535750. eCollection 2018.

17.

Liposomal drug delivery in an in vitro 3D bone marrow model for multiple myeloma.

Braham MV, Deshantri AK, Minnema MC, Öner FC, Schiffelers RM, Fens MH, Alblas J.

Int J Nanomedicine. 2018 Nov 29;13:8105-8118. doi: 10.2147/IJN.S184262. eCollection 2018.

18.

The fluid membrane determines mechanics of erythrocyte extracellular vesicles and is softened in hereditary spherocytosis.

Vorselen D, van Dommelen SM, Sorkin R, Piontek MC, Schiller J, Döpp ST, Kooijmans SAA, van Oirschot BA, Versluijs BA, Bierings MB, van Wijk R, Schiffelers RM, Wuite GJL, Roos WH.

Nat Commun. 2018 Nov 23;9(1):4960. doi: 10.1038/s41467-018-07445-x.

19.

Effect of Formulation and Processing Parameters on the Size of mPEG- b-p(HPMA-Bz) Polymeric Micelles.

Bagheri M, Bresseleers J, Varela-Moreira A, Sandre O, Meeuwissen SA, Schiffelers RM, Metselaar JM, van Nostrum CF, van Hest JCM, Hennink WE.

Langmuir. 2018 Dec 18;34(50):15495-15506. doi: 10.1021/acs.langmuir.8b03576. Epub 2018 Nov 26.

20.

Thermosensitive liposomes for triggered release of cytotoxic proteins.

de Matos MBC, Beztsinna N, Heyder C, Fens MHAM, Mastrobattista E, Schiffelers RM, Leneweit G, Kok RJ.

Eur J Pharm Biopharm. 2018 Nov;132:211-221. doi: 10.1016/j.ejpb.2018.09.010. Epub 2018 Sep 14.

21.

Nanomedicines for the treatment of hematological malignancies.

Deshantri AK, Varela Moreira A, Ecker V, Mandhane SN, Schiffelers RM, Buchner M, Fens MHAM.

J Control Release. 2018 Oct 10;287:194-215. doi: 10.1016/j.jconrel.2018.08.034. Epub 2018 Aug 28. Review.

PMID:
30165140
22.

Nanomechanics of Extracellular Vesicles Reveals Vesiculation Pathways.

Sorkin R, Huisjes R, Bošković F, Vorselen D, Pignatelli S, Ofir-Birin Y, Freitas Leal JK, Schiller J, Mullick D, Roos WH, Bosman G, Regev-Rudzki N, Schiffelers RM, Wuite GJL.

Small. 2018 Sep;14(39):e1801650. doi: 10.1002/smll.201801650. Epub 2018 Aug 30.

PMID:
30160371
23.

Squeezing for Life - Properties of Red Blood Cell Deformability.

Huisjes R, Bogdanova A, van Solinge WW, Schiffelers RM, Kaestner L, van Wijk R.

Front Physiol. 2018 Jun 1;9:656. doi: 10.3389/fphys.2018.00656. eCollection 2018. Review.

24.

Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles.

Steenbeek SC, Pham TV, de Ligt J, Zomer A, Knol JC, Piersma SR, Schelfhorst T, Huisjes R, Schiffelers RM, Cuppen E, Jimenez CR, van Rheenen J.

EMBO J. 2018 Aug 1;37(15). pii: e98357. doi: 10.15252/embj.201798357. Epub 2018 Jun 14.

25.

Environmental impact of switching from the synthetic glucocorticoid prednisolone to the natural alkaloid berberine.

Allijn IE, Oldenkamp R, Storm G, Ragas AMJ, Schiffelers RM.

PLoS One. 2018 Jun 14;13(6):e0199095. doi: 10.1371/journal.pone.0199095. eCollection 2018.

26.

Quantitative measurement of red cell surface protein expression reveals new biomarkers for hereditary spherocytosis.

Huisjes R, Satchwell TJ, Verhagen LP, Schiffelers RM, van Solinge WW, Toye AM, van Wijk R.

Int J Lab Hematol. 2018 Aug;40(4):e74-e77. doi: 10.1111/ijlh.12841. Epub 2018 May 10. No abstract available.

PMID:
29746727
27.

Insights into maleimide-thiol conjugation chemistry: Conditions for efficient surface functionalization of nanoparticles for receptor targeting.

Martínez-Jothar L, Doulkeridou S, Schiffelers RM, Sastre Torano J, Oliveira S, van Nostrum CF, Hennink WE.

J Control Release. 2018 Jul 28;282:101-109. doi: 10.1016/j.jconrel.2018.03.002. Epub 2018 Mar 9.

PMID:
29526739
28.

Recombinant phosphatidylserine-binding nanobodies for targeting of extracellular vesicles to tumor cells: a plug-and-play approach.

Kooijmans SAA, Gitz-Francois JJJM, Schiffelers RM, Vader P.

Nanoscale. 2018 Feb 1;10(5):2413-2426. doi: 10.1039/c7nr06966a.

29.

Extracellular vesicles in diagnostics and therapy of the ischaemic heart: Position Paper from the Working Group on Cellular Biology of the Heart of the European Society of Cardiology.

Sluijter JPG, Davidson SM, Boulanger CM, Buzás EI, de Kleijn DPV, Engel FB, Giricz Z, Hausenloy DJ, Kishore R, Lecour S, Leor J, Madonna R, Perrino C, Prunier F, Sahoo S, Schiffelers RM, Schulz R, Van Laake LW, Ytrehus K, Ferdinandy P.

Cardiovasc Res. 2018 Jan 1;114(1):19-34. doi: 10.1093/cvr/cvx211. Review.

30.

Bioinspired Cell-Derived Nanovesicles versus Exosomes as Drug Delivery Systems: a Cost-Effective Alternative.

Goh WJ, Zou S, Ong WY, Torta F, Alexandra AF, Schiffelers RM, Storm G, Wang JW, Czarny B, Pastorin G.

Sci Rep. 2017 Oct 30;7(1):14322. doi: 10.1038/s41598-017-14725-x.

31.

Cellular uptake of extracellular vesicles is mediated by clathrin-independent endocytosis and macropinocytosis.

Costa Verdera H, Gitz-Francois JJ, Schiffelers RM, Vader P.

J Control Release. 2017 Nov 28;266:100-108. doi: 10.1016/j.jconrel.2017.09.019. Epub 2017 Sep 14.

32.

Microbubbles-Assisted Ultrasound Triggers the Release of Extracellular Vesicles.

Yuana Y, Jiang L, Lammertink BHA, Vader P, Deckers R, Bos C, Schiffelers RM, Moonen CT.

Int J Mol Sci. 2017 Jul 25;18(8). pii: E1610. doi: 10.3390/ijms18081610.

33.

Tumour-bound RNA-laden exosomes.

Kooijmans SAA, Vader P, Schiffelers RM.

Nat Biomed Eng. 2017 Aug;1(8):634-636. doi: 10.1038/s41551-017-0119-4. No abstract available.

PMID:
31015606
34.

Functional Delivery of Lipid-Conjugated siRNA by Extracellular Vesicles.

O'Loughlin AJ, Mäger I, de Jong OG, Varela MA, Schiffelers RM, El Andaloussi S, Wood MJA, Vader P.

Mol Ther. 2017 Jul 5;25(7):1580-1587. doi: 10.1016/j.ymthe.2017.03.021. Epub 2017 Apr 6.

35.

Obstacles and opportunities in the functional analysis of extracellular vesicle RNA - an ISEV position paper.

Mateescu B, Kowal EJ, van Balkom BW, Bartel S, Bhattacharyya SN, Buzás EI, Buck AH, de Candia P, Chow FW, Das S, Driedonks TA, Fernández-Messina L, Haderk F, Hill AF, Jones JC, Van Keuren-Jensen KR, Lai CP, Lässer C, Liegro ID, Lunavat TR, Lorenowicz MJ, Maas SL, Mäger I, Mittelbrunn M, Momma S, Mukherjee K, Nawaz M, Pegtel DM, Pfaffl MW, Schiffelers RM, Tahara H, Théry C, Tosar JP, Wauben MH, Witwer KW, Nolte-'t Hoen EN.

J Extracell Vesicles. 2017 Mar 7;6(1):1286095. doi: 10.1080/20013078.2017.1286095. eCollection 2017.

36.

In Situ Gelling Liquid Crystalline System as Local siRNA Delivery System.

Borgheti-Cardoso LN, Kooijmans SAA, Fens MHAM, van der Meel R, Vicentini FTMC, Fantini MCA, Bentley MVLB, Schiffelers RM.

Mol Pharm. 2017 May 1;14(5):1681-1690. doi: 10.1021/acs.molpharmaceut.6b01141. Epub 2017 Mar 28.

PMID:
28291360
37.

Extracellular vesicles for nucleic acid delivery: progress and prospects for safe RNA-based gene therapy.

Jiang L, Vader P, Schiffelers RM.

Gene Ther. 2017 Mar;24(3):157-166. doi: 10.1038/gt.2017.8. Epub 2017 Jan 31. Review.

PMID:
28140387
38.

Liposome encapsulated berberine treatment attenuates cardiac dysfunction after myocardial infarction.

Allijn IE, Czarny BMS, Wang X, Chong SY, Weiler M, da Silva AE, Metselaar JM, Lam CSP, Pastorin G, de Kleijn DPV, Storm G, Wang JW, Schiffelers RM.

J Control Release. 2017 Feb 10;247:127-133. doi: 10.1016/j.jconrel.2016.12.042. Epub 2017 Jan 5.

PMID:
28065862
39.

Interaction of Extracellular Vesicles with Endothelial Cells Under Physiological Flow Conditions.

van Dommelen SM, Fish M, Barendrecht AD, Schiffelers RM, Eniola-Adefeso O, Vader P.

Methods Mol Biol. 2017;1545:205-213.

PMID:
27943217
40.

Liposomal prednisolone inhibits tumor growth in a spontaneous mouse mammary carcinoma model.

Deshantri AK, Kooijmans SA, Kuijpers SA, Coimbra M, Hoeppener A, Storm G, Fens MH, Schiffelers RM.

J Control Release. 2016 Dec 10;243:243-249. doi: 10.1016/j.jconrel.2016.10.016. Epub 2016 Oct 20.

PMID:
27773734
41.

ADDR editorial "Biologically-inspired drug delivery systems".

Vader P, Schiffelers RM.

Adv Drug Deliv Rev. 2016 Nov 15;106(Pt A):1-2. doi: 10.1016/j.addr.2016.10.004. No abstract available.

PMID:
27794378
42.

Extracellular vesicles for drug delivery.

Vader P, Mol EA, Pasterkamp G, Schiffelers RM.

Adv Drug Deliv Rev. 2016 Nov 15;106(Pt A):148-156. doi: 10.1016/j.addr.2016.02.006. Epub 2016 Feb 27. Review.

PMID:
26928656
43.

Modulation of tissue tropism and biological activity of exosomes and other extracellular vesicles: New nanotools for cancer treatment.

Kooijmans SAA, Schiffelers RM, Zarovni N, Vago R.

Pharmacol Res. 2016 Sep;111:487-500. doi: 10.1016/j.phrs.2016.07.006. Epub 2016 Jul 6. Review.

PMID:
27394168
44.

Head-to-Head Comparison of Anti-Inflammatory Performance of Known Natural Products In Vitro.

Allijn IE, Vaessen SF, Quarles van Ufford LC, Beukelman KJ, de Winther MP, Storm G, Schiffelers RM.

PLoS One. 2016 May 10;11(5):e0155325. doi: 10.1371/journal.pone.0155325. eCollection 2016.

45.

Comparison of pharmaceutical nanoformulations for curcumin: Enhancement of aqueous solubility and carrier retention.

Allijn IE, Schiffelers RM, Storm G.

Int J Pharm. 2016 Jun 15;506(1-2):407-13. doi: 10.1016/j.ijpharm.2016.04.070. Epub 2016 Apr 29.

PMID:
27139142
46.

Lipid-based Transfection Reagents Exhibit Cryo-induced Increase in Transfection Efficiency.

Sork H, Nordin JZ, Turunen JJ, Wiklander OP, Bestas B, Zaghloul EM, Margus H, Padari K, Duru AD, Corso G, Bost J, Vader P, Pooga M, Smith CE, Wood MJ, Schiffelers RM, Hällbrink M, Andaloussi SE.

Mol Ther Nucleic Acids. 2016 Mar 8;5:e290. doi: 10.1038/mtna.2016.8.

47.

Cetuximab treatment alters the content of extracellular vesicles released from tumor cells.

van Dommelen SM, van der Meel R, van Solinge WW, Coimbra M, Vader P, Schiffelers RM.

Nanomedicine (Lond). 2016 Apr;11(8):881-90. doi: 10.2217/nnm-2015-0009. Epub 2016 Mar 16.

PMID:
27021928
48.

Display of GPI-anchored anti-EGFR nanobodies on extracellular vesicles promotes tumour cell targeting.

Kooijmans SA, Aleza CG, Roffler SR, van Solinge WW, Vader P, Schiffelers RM.

J Extracell Vesicles. 2016 Mar 14;5:31053. doi: 10.3402/jev.v5.31053. eCollection 2016.

49.

PEGylated and targeted extracellular vesicles display enhanced cell specificity and circulation time.

Kooijmans SAA, Fliervoet LAL, van der Meel R, Fens MHAM, Heijnen HFG, van Bergen En Henegouwen PMP, Vader P, Schiffelers RM.

J Control Release. 2016 Feb 28;224:77-85. doi: 10.1016/j.jconrel.2016.01.009. Epub 2016 Jan 7.

PMID:
26773767
50.

Silencing of protease-activated receptors attenuates synovitis and cartilage damage following a joint bleed in haemophilic mice.

Nieuwenhuizen L, Schutgens RE, Coeleveld K, Mastbergen SC, Schiffelers RM, Roosendaal G, Biesma DH, Lafeber FP.

Haemophilia. 2016 Jan;22(1):152-9. doi: 10.1111/hae.12770. Epub 2015 Jul 20.

PMID:
26189554

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