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Items: 1 to 50 of 173

1.

Intestinal bacterial indicator phylotypes associate with impaired DNA double-stranded break sensors but augmented skeletal bone micro-structure.

Maier I, Liu J, Ruegger PM, Deutschmann J, Patsch JM, Helbich TH, Borneman J, Schiestl RH.

Carcinogenesis. 2019 Dec 16. pii: bgz204. doi: 10.1093/carcin/bgz204. [Epub ahead of print]

PMID:
31840161
2.

A novel probiotic, Lactobacillus johnsonii 456, resists acid and can persist in the human gut beyond the initial ingestion period.

Davoren MJ, Liu J, Castellanos J, Rodríguez-Malavé NI, Schiestl RH.

Gut Microbes. 2019;10(4):458-480. doi: 10.1080/19490976.2018.1547612. Epub 2018 Dec 22.

3.

Retraction Note to: Mouse models of intestinal inflammation and cancer.

Westbrook AM, Szakmary A, Schiestl RH.

Arch Toxicol. 2018 Nov;92(11):3441. doi: 10.1007/s00204-018-2312-y.

PMID:
30267108
4.

Glyphosate-based herbicides and cancer risk: a post-IARC decision review of potential mechanisms, policy and avenues of research.

Davoren MJ, Schiestl RH.

Carcinogenesis. 2018 Oct 8;39(10):1207-1215. doi: 10.1093/carcin/bgy105. Review.

PMID:
30060078
5.

Involvement of UDP-Glucuronosyltransferases and Sulfotransferases in the Excretion and Tissue Distribution of Resveratrol in Mice.

Böhmdorfer M, Szakmary A, Schiestl RH, Vaquero J, Riha J, Brenner S, Thalhammer T, Szekeres T, Jäger W.

Nutrients. 2017 Dec 12;9(12). pii: E1347. doi: 10.3390/nu9121347.

6.

MEF2C protects bone marrow B-lymphoid progenitors during stress haematopoiesis.

Wang W, Org T, Montel-Hagen A, Pioli PD, Duan D, Israely E, Malkin D, Su T, Flach J, Kurdistani SK, Schiestl RH, Mikkola HK.

Nat Commun. 2016 Aug 10;7:12376. doi: 10.1038/ncomms12376.

7.

Mouse models of intestinal inflammation and cancer.

Westbrook AM, Szakmary A, Schiestl RH.

Arch Toxicol. 2016 Sep;90(9):2109-2130. doi: 10.1007/s00204-016-1747-2. Epub 2016 Jun 16. Review. Retraction in: Arch Toxicol. 2018 Nov;92(11):3441.

PMID:
27311821
8.

Mouse models for radiation-induced cancers.

Rivina L, Davoren MJ, Schiestl RH.

Mutagenesis. 2016 Sep;31(5):491-509. doi: 10.1093/mutage/gew019. Epub 2016 May 21. Review.

9.

Chemopreventive Metabolites Are Correlated with a Change in Intestinal Microbiota Measured in A-T Mice and Decreased Carcinogenesis.

Cheema AK, Maier I, Dowdy T, Wang Y, Singh R, Ruegger PM, Borneman J, Fornace AJ Jr, Schiestl RH.

PLoS One. 2016 Apr 13;11(4):e0151190. doi: 10.1371/journal.pone.0151190. eCollection 2016.

10.

Requirement of POL3 and POL4 on non-homologous and microhomology-mediated end joining in rad50/xrs2 mutants of Saccharomyces cerevisiae.

Galli A, Chan CY, Parfenova L, Cervelli T, Schiestl RH.

Mutagenesis. 2015 Nov;30(6):841-9. doi: 10.1093/mutage/gev046. Epub 2015 Jun 29.

11.
12.

IL-13 overexpression in mouse lungs triggers systemic genotoxicity in peripheral blood.

Chapmana AM, Malkin DJ, Camacho J, Schiestl RH.

Mutat Res. 2014 Nov;769:100-7.

13.

Lymphoma caused by intestinal microbiota.

Yamamoto ML, Schiestl RH.

Int J Environ Res Public Health. 2014 Sep 1;11(9):9038-49. doi: 10.3390/ijerph110909038. Review.

14.

Radiation-induced myeloid leukemia in murine models.

Rivina L, Davoren M, Schiestl RH.

Hum Genomics. 2014 Jul 25;8:13. doi: 10.1186/1479-7364-8-13. Review.

15.

Intestinal microbiome and lymphoma development.

Yamamoto ML, Schiestl RH.

Cancer J. 2014 May-Jun;20(3):190-4. doi: 10.1097/PPO.0000000000000047. Review.

16.

Intestinal microbiota reduces genotoxic endpoints induced by high-energy protons.

Maier I, Berry DM, Schiestl RH.

Radiat Res. 2014 Jan;181(1):45-53. doi: 10.1667/RR13352.1. Epub 2014 Jan 7.

PMID:
24397477
17.

Intestinal bacteria modify lymphoma incidence and latency by affecting systemic inflammatory state, oxidative stress, and leukocyte genotoxicity.

Yamamoto ML, Maier I, Dang AT, Berry D, Liu J, Ruegger PM, Yang JI, Soto PA, Presley LL, Reliene R, Westbrook AM, Wei B, Loy A, Chang C, Braun J, Borneman J, Schiestl RH.

Cancer Res. 2013 Jul 15;73(14):4222-32. doi: 10.1158/0008-5472.CAN-13-0022.

18.
19.

Effects of side-stream tobacco smoke and smoke extract on glutathione- and oxidative DNA damage repair-deficient mice and blood cells.

Yamamoto ML, Chapman AM, Schiestl RH.

Mutat Res. 2013 Sep;749(1-2):58-65. doi: 10.1016/j.mrfmmm.2013.05.003. Epub 2013 Jun 5.

20.

Transcriptome analysis of a rotenone model of parkinsonism reveals complex I-tied and -untied toxicity mechanisms common to neurodegenerative diseases.

Cabeza-Arvelaiz Y, Schiestl RH.

PLoS One. 2012;7(9):e44700. doi: 10.1371/journal.pone.0044700. Epub 2012 Sep 7.

21.

Analysis of striatal transcriptome in mice overexpressing human wild-type alpha-synuclein supports synaptic dysfunction and suggests mechanisms of neuroprotection for striatal neurons.

Cabeza-Arvelaiz Y, Fleming SM, Richter F, Masliah E, Chesselet MF, Schiestl RH.

Mol Neurodegener. 2011 Dec 13;6:83. doi: 10.1186/1750-1326-6-83.

22.

Intracellular and extracellular factors influencing Cr(VI) and Cr(III) genotoxicity.

Sobol Z, Schiestl RH.

Environ Mol Mutagen. 2012 Mar;53(2):94-100. doi: 10.1002/em.20679. Epub 2011 Oct 21.

PMID:
22020802
23.

Combined preconditioning and in vivo chemoselection with 6-thioguanine alone achieves highly efficient reconstitution of normal hematopoiesis with HPRT-deficient bone marrow.

Hacke K, Szakmary A, Cuddihy AR, Rozengurt N, Lemp NA, Aubrecht J, Lawson GW, Rao NP, Crooks GM, Schiestl RH, Kasahara N.

Exp Hematol. 2012 Jan;40(1):3-13.e3. doi: 10.1016/j.exphem.2011.09.009. Epub 2011 Oct 12.

24.

The role of tumour necrosis factor-α and tumour necrosis factor receptor signalling in inflammation-associated systemic genotoxicity.

Westbrook AM, Wei B, Hacke K, Xia M, Braun J, Schiestl RH.

Mutagenesis. 2012 Jan;27(1):77-86. doi: 10.1093/mutage/ger063. Epub 2011 Oct 6.

25.

A high G418-resistant neo(R) transgenic mouse and mouse embryonic fibroblast (MEF) feeder layers for cytotoxicity and gene targeting in vivo and in vitro.

Aubrecht J, Goad ME, Czopik AK, Lerner CP, Johnson KA, Simpson EM, Schiestl RH.

Drug Chem Toxicol. 2011 Oct;34(4):433-9. doi: 10.3109/01480545.2010.544316. Epub 2011 Jul 11.

PMID:
21740348
26.

Intestinal inflammation induces genotoxicity to extraintestinal tissues and cell types in mice.

Westbrook AM, Wei B, Braun J, Schiestl RH.

Int J Cancer. 2011 Oct 15;129(8):1815-25. doi: 10.1002/ijc.26146. Epub 2011 Aug 2.

27.

Effect of rad50 mutation on illegitimate recombination in Saccharomyces cerevisiae.

Chan CY, Zhu J, Schiestl RH.

Mol Genet Genomics. 2011 Jun;285(6):471-84. doi: 10.1007/s00438-011-0619-y. Epub 2011 Apr 22.

PMID:
21512733
28.

High throughput screening of small molecule libraries for modifiers of radiation responses.

Kim K, Damoiseaux R, Norris AJ, Rivina L, Bradley K, Jung ME, Gatti RA, Schiestl RH, McBride WH.

Int J Radiat Biol. 2011 Aug;87(8):839-45. doi: 10.3109/09553002.2011.560994. Epub 2011 Mar 14.

29.

Effects of 1 GeV/nucleon ⁵⁶Fe particles on longevity, carcinogenesis and neuromotor ability in Atm-deficient mice.

Yamamoto ML, Hafer K, Reliene R, Fleming S, Kelly O, Hacke K, Schiestl RH.

Radiat Res. 2011 Feb;175(2):231-9. Epub 2010 Nov 23.

PMID:
21268717
30.

Yeast DEL assay detects protection against radiation-induced cytotoxicity and genotoxicity: adaptation of a microtiter plate version.

Hafer K, Rivina Y, Schiestl RH.

Radiat Res. 2010 Dec;174(6):719-26. doi: 10.1667/RR2059.1. Epub 2010 Sep 20.

31.

Genomic instability in mice is greater in Fanconi anemia caused by deficiency of Fancd2 than Fancg.

Reliene R, Yamamoto ML, Rao PN, Schiestl RH.

Cancer Res. 2010 Dec 1;70(23):9703-10. doi: 10.1158/0008-5472.CAN-09-1022. Epub 2010 Nov 30.

32.

Effects of 1 GeV/nucleon (56)Fe Particles on Longevity, Carcinogenesis and Neuromotor Ability in Atm-Deficient Mice.

Yamamoto ML, Hafer K, Reliene R, Fleming S, Kelly O, Hacke K, Schiestl RH.

Radiat Res. 2010 Nov 23. [Epub ahead of print]

PMID:
21091324
33.

New and emerging technologies for genetic toxicity testing.

Lynch AM, Sasaki JC, Elespuru R, Jacobson-Kram D, Thybaud V, De Boeck M, Aardema MJ, Aubrecht J, Benz RD, Dertinger SD, Douglas GR, White PA, Escobar PA, Fornace A Jr, Honma M, Naven RT, Rusling JF, Schiestl RH, Walmsley RM, Yamamura E, van Benthem J, Kim JH.

Environ Mol Mutagen. 2011 Apr;52(3):205-23. doi: 10.1002/em.20614. Epub 2010 Aug 25. Review.

PMID:
20740635
34.

Ty1 integrase overexpression leads to integration of non-Ty1 DNA fragments into the genome of Saccharomyces cerevisiae.

Friedl AA, Kiechle M, Maxeiner HG, Schiestl RH, Eckardt-Schupp F.

Mol Genet Genomics. 2010 Oct;284(4):231-42. doi: 10.1007/s00438-010-0561-4. Epub 2010 Jul 31. Review.

35.

Small-animal PET/CT for monitoring the development and response to chemotherapy of thymic lymphoma in Trp53-/- mice.

Walter MA, Hildebrandt IJ, Hacke K, Kesner AL, Kelly O, Lawson GW, Phelps ME, Czernin J, Weber WA, Schiestl RH.

J Nucl Med. 2010 Aug;51(8):1285-92. doi: 10.2967/jnumed.109.073585. Epub 2010 Jul 21.

36.
37.

Mechanisms of intestinal inflammation and development of associated cancers: lessons learned from mouse models.

Westbrook AM, Szakmary A, Schiestl RH.

Mutat Res. 2010 Jul-Sep;705(1):40-59. doi: 10.1016/j.mrrev.2010.03.001. Epub 2010 Mar 16. Review.

38.

Atm-deficient mice exhibit increased sensitivity to dextran sulfate sodium-induced colitis characterized by elevated DNA damage and persistent immune activation.

Westbrook AM, Schiestl RH.

Cancer Res. 2010 Mar 1;70(5):1875-84. doi: 10.1158/0008-5472.CAN-09-2584. Epub 2010 Feb 23.

39.

Titanium dioxide nanoparticles induce DNA damage and genetic instability in vivo in mice.

Trouiller B, Reliene R, Westbrook A, Solaimani P, Schiestl RH.

Cancer Res. 2009 Nov 15;69(22):8784-9. doi: 10.1158/0008-5472.CAN-09-2496. Epub 2009 Nov 3.

40.

The pol3-t hyperrecombination phenotype and DNA damage-induced recombination in Saccharomyces cerevisiae is RAD50 dependent.

Galli A, Hafer K, Cervelli T, Schiestl RH.

J Biomed Biotechnol. 2009;2009:312710. doi: 10.1155/2009/312710. Epub 2009 Oct 12.

41.

More damaging than we think: systemic effects of intestinal inflammation.

Westbrook AM, Wei B, Braun J, Schiestl RH.

Cell Cycle. 2009 Aug 15;8(16):2482-3. Epub 2009 Aug 15. No abstract available.

43.

Intestinal mucosal inflammation leads to systemic genotoxicity in mice.

Westbrook AM, Wei B, Braun J, Schiestl RH.

Cancer Res. 2009 Jun 1;69(11):4827-34. doi: 10.1158/0008-5472.CAN-08-4416.

44.

N-acetyl cysteine protects against ionizing radiation-induced DNA damage but not against cell killing in yeast and mammals.

Reliene R, Pollard JM, Sobol Z, Trouiller B, Gatti RA, Schiestl RH.

Mutat Res. 2009 Jun 1;665(1-2):37-43. doi: 10.1016/j.mrfmmm.2009.02.016. Epub 2009 Mar 13.

PMID:
19427509
45.

Ionizing radiation induces microhomology-mediated end joining in trans in yeast and mammalian cells.

Scuric Z, Chan CY, Hafer K, Schiestl RH.

Radiat Res. 2009 Apr;171(4):454-63. doi: 10.1667/RR1329.1.

46.

Biological aspects of dichlorofluorescein measurement of cellular reactive oxygen species.

Hafer K, Schiestl RH.

Radiat Res. 2008 Sep;170(3):408. doi: 10.1667/RR1439c.1. No abstract available.

PMID:
18763872
47.

Effects of human Werner helicase on intrachromosomal homologous recombination mediated DNA deletions in mice.

Yamamoto ML, Reliene R, Oshima J, Schiestl RH.

Mutat Res. 2008 Sep 26;644(1-2):11-6. doi: 10.1016/j.mrfmmm.2008.06.008. Epub 2008 Jul 1.

PMID:
18639560
48.

Pol3 is involved in nonhomologous end-joining in Saccharomyces cerevisiae.

Chan CY, Galli A, Schiestl RH.

DNA Repair (Amst). 2008 Sep 1;7(9):1531-41. doi: 10.1016/j.dnarep.2008.05.008. Epub 2008 Jul 7.

PMID:
18606574
49.
50.

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