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Core lipid, surface lipid and apolipoprotein composition analysis of lipoprotein particles as a function of particle size in one workflow integrating asymmetric flow field-flow fractionation and liquid chromatography-tandem mass spectrometry.

Kuklenyik Z, Jones JI, Gardner MS, Schieltz DM, Parks BA, Toth CA, Rees JC, Andrews ML, Carter K, Lehtikoski AK, McWilliams LG, Williamson YM, Bierbaum KP, Pirkle JL, Barr JR.

PLoS One. 2018 Apr 10;13(4):e0194797. doi: 10.1371/journal.pone.0194797. eCollection 2018.


Surfaceome Analysis Protocol for the Identification of Novel Bordetella pertussis Antigens.

Williamson YM, Whitmon J, West-Deadwyler R, Moura H, Woolfitt AR, Rees J, Schieltz DM, Barr JR.

Methods Mol Biol. 2018;1722:3-20. doi: 10.1007/978-1-4939-7553-2_1.


High throughput quantification of apolipoproteins A-I and B-100 by isotope dilution MS targeting fast trypsin releasable peptides without reduction and alkylation.

Parks BA, Schieltz DM, Andrews ML, Gardner MS, Rees JC, Toth CA, Jones JI, McWilliams LG, Kuklenyik Z, Pirkle JL, Barr JR.

Proteomics Clin Appl. 2017 Jul;11(7-8). doi: 10.1002/prca.201600128. Epub 2017 Apr 3.


Complete Genome Sequences of Four Bordetella pertussis Vaccine Reference Strains from Serum Institute of India.

Weigand MR, Peng Y, Loparev V, Johnson T, Juieng P, Gairola S, Kumar R, Shaligram U, Gowrishankar R, Moura H, Rees J, Schieltz DM, Williamson Y, Woolfitt A, Barr J, Tondella ML, Williams MM.

Genome Announc. 2016 Dec 22;4(6). pii: e01404-16. doi: 10.1128/genomeA.01404-16.


On-column trypsin digestion coupled with LC-MS/MS for quantification of apolipoproteins.

Toth CA, Kuklenyik Z, Jones JI, Parks BA, Gardner MS, Schieltz DM, Rees JC, Andrews ML, McWilliams LG, Pirkle JL, Barr JR.

J Proteomics. 2017 Jan 6;150:258-267. doi: 10.1016/j.jprot.2016.09.011. Epub 2016 Sep 23.


Recommended Mass Spectrometry-Based Strategies to Identify Ricin-Containing Samples.

Kalb SR, Schieltz DM, Becher F, Astot C, Fredriksson SÅ, Barr JR.

Toxins (Basel). 2015 Nov 25;7(12):4881-94. doi: 10.3390/toxins7124854.


A Proteomic Characterization of Bordetella pertussis Clinical Isolates Associated with a California State Pertussis Outbreak.

Williamson YM, Moura H, Whitmon J, Woolfitt AR, Schieltz DM, Rees JC, Guo S, Kirkham H, Bouck D, Ades EW, Tondella ML, Carlone GM, Sampson JS, Barr JR.

Int J Proteomics. 2015;2015:536537. doi: 10.1155/2015/536537. Epub 2015 May 24.


Simultaneous Identification and Susceptibility Determination to Multiple Antibiotics of Staphylococcus aureus by Bacteriophage Amplification Detection Combined with Mass Spectrometry.

Rees JC, Pierce CL, Schieltz DM, Barr JR.

Anal Chem. 2015 Jul 7;87(13):6769-77. doi: 10.1021/acs.analchem.5b00959. Epub 2015 Jun 8.


Quantification of ricin, RCA and comparison of enzymatic activity in 18 Ricinus communis cultivars by isotope dilution mass spectrometry.

Schieltz DM, McWilliams LG, Kuklenyik Z, Prezioso SM, Carter AJ, Williamson YM, McGrath SC, Morse SA, Barr JR.

Toxicon. 2015 Mar;95:72-83. doi: 10.1016/j.toxicon.2015.01.003. Epub 2015 Jan 7.


A gel-free proteomic-based method for the characterization of Bordetella pertussis clinical isolates.

Williamson YM, Moura H, Simmons K, Whitmon J, Melnick N, Rees J, Woolfitt A, Schieltz DM, Tondella ML, Ades E, Sampson J, Carlone G, Barr JR.

J Microbiol Methods. 2012 Aug;90(2):119-33. doi: 10.1016/j.mimet.2012.04.007. Epub 2012 Apr 18.


A rapid method for capture and identification of immunogenic proteins in Bordetella pertussis enriched membranes fractions: a fast-track strategy applicable to other microorganisms.

West R, Whitmon J, Williamson YM, Moura H, Nelson M, Melnick N, Tondella ML, Schieltz D, Rees J, Woolfitt AR, Barr JR, Ades EW, Carlone GM, Sampson JS.

J Proteomics. 2012 Mar 16;75(6):1966-72. doi: 10.1016/j.jprot.2011.12.034. Epub 2012 Jan 5.


A historical and proteomic analysis of botulinum neurotoxin type/G.

Terilli RR, Moura H, Woolfitt AR, Rees J, Schieltz DM, Barr JR.

BMC Microbiol. 2011 Oct 18;11:232. doi: 10.1186/1471-2180-11-232.


Detection and quantification of ricin in beverages using isotope dilution tandem mass spectrometry.

McGrath SC, Schieltz DM, McWilliams LG, Pirkle JL, Barr JR.

Anal Chem. 2011 Apr 15;83(8):2897-905. doi: 10.1021/ac102571f. Epub 2011 Mar 23.


Analysis of active ricin and castor bean proteins in a ricin preparation, castor bean extract, and surface swabs from a public health investigation.

Schieltz DM, McGrath SC, McWilliams LG, Rees J, Bowen MD, Kools JJ, Dauphin LA, Gomez-Saladin E, Newton BN, Stang HL, Vick MJ, Thomas J, Pirkle JL, Barr JR.

Forensic Sci Int. 2011 Jun 15;209(1-3):70-9. doi: 10.1016/j.forsciint.2010.12.013. Epub 2011 Jan 19.


The Zds proteins control entry into mitosis and target protein phosphatase 2A to the Cdc25 phosphatase.

Wicky S, Tjandra H, Schieltz D, Yates J 3rd, Kellogg DR.

Mol Biol Cell. 2011 Jan 1;22(1):20-32. doi: 10.1091/mbc.E10-06-0487. Epub 2010 Nov 30.


Mass spectrometric analysis of multiple pertussis toxins and toxoids.

Williamson YM, Moura H, Schieltz D, Rees J, Woolfitt AR, Pirkle JL, Sampson JS, Tondella ML, Ades E, Carlone G, Barr JR.

J Biomed Biotechnol. 2010;2010:942365. doi: 10.1155/2010/942365. Epub 2010 May 23.


Digestion of Insoluble Protein Fractions for Multidimensional Protein Identification Technology (MuDPIT) Analysis.

Schieltz DM, Washburn MP.

CSH Protoc. 2006 Oct 1;2006(5). pii: pdb.prot4556. doi: 10.1101/pdb.prot4556.


Analysis of Complex Protein Mixtures Using Multidimensional Protein Identification Technology (MuDPIT).

Schieltz DM, Washburn MP.

CSH Protoc. 2006 Oct 1;2006(5). pii: pdb.prot4555. doi: 10.1101/pdb.prot4555.


Tandem Mass Spectrometry Analysis Using the ThermoFinnigan LCQ System.

Schieltz DM, Washburn MP, Hays LG.

CSH Protoc. 2006 Oct 1;2006(5). pii: pdb.prot4554. doi: 10.1101/pdb.prot4554.


Analysis of Complex Protein Mixtures Using Nano-LC Coupled to MS/MS.

Schieltz DM, Washburn MP, Hays LG.

CSH Protoc. 2006 Oct 1;2006(5). pii: pdb.prot4553. doi: 10.1101/pdb.prot4553.


The use of mass spectrometry in proteomics: database searching.

Schieltz DM, Washburn MP, Hays LG.

CSH Protoc. 2006 Oct 1;2006(5). pii: pdb.ip5. doi: 10.1101/pdb.ip5. No abstract available.


Polyglutamine-expanded spinocerebellar ataxia-7 protein disrupts normal SAGA and SLIK histone acetyltransferase activity.

McMahon SJ, Pray-Grant MG, Schieltz D, Yates JR 3rd, Grant PA.

Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8478-82. Epub 2005 Jun 2.


Chd1 chromodomain links histone H3 methylation with SAGA- and SLIK-dependent acetylation.

Pray-Grant MG, Daniel JA, Schieltz D, Yates JR 3rd, Grant PA.

Nature. 2005 Jan 27;433(7024):434-8. Epub 2005 Jan 12.


Biochemical and genetic characterization of Yra1p in budding yeast.

Kashyap AK, Schieltz D, Yates J 3rd, Kellogg DR.

Yeast. 2005 Jan 15;22(1):43-56.


Analysis of high-mannose-type oligosaccharides by microliquid chromatography-mass spectrometry and capillary electrophoresis.

Koller A, Khandurina J, Li J, Kreps J, Schieltz D, Guttman A.

Electrophoresis. 2004 Jul;25(13):2003-9.


Deubiquitination of histone H2B by a yeast acetyltransferase complex regulates transcription.

Daniel JA, Torok MS, Sun ZW, Schieltz D, Allis CD, Yates JR 3rd, Grant PA.

J Biol Chem. 2004 Jan 16;279(3):1867-71. Epub 2003 Dec 3.


Direct identification of proteins in ultracomplex mixtures. Applications to proteome analysis.

Schieltz DM, Yates JR 3rd.

Methods Mol Biol. 2003;211:235-45. No abstract available.


The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.

Pray-Grant MG, Schieltz D, McMahon SJ, Wood JM, Kennedy EL, Cook RG, Workman JL, Yates JR 3rd, Grant PA.

Mol Cell Biol. 2002 Dec;22(24):8774-86.


One-step affinity purification of the yeast ribosome and its associated proteins and mRNAs.

Inada T, Winstall E, Tarun SZ Jr, Yates JR 3rd, Schieltz D, Sachs AB.

RNA. 2002 Jul;8(7):948-58.


Proteomic survey of metabolic pathways in rice.

Koller A, Washburn MP, Lange BM, Andon NL, Deciu C, Haynes PA, Hays L, Schieltz D, Ulaszek R, Wei J, Wolters D, Yates JR 3rd.

Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11969-74. Epub 2002 Aug 5.


Analysis of quantitative proteomic data generated via multidimensional protein identification technology.

Washburn MP, Ulaszek R, Deciu C, Schieltz DM, Yates JR 3rd.

Anal Chem. 2002 Apr 1;74(7):1650-7.


Dynamic interaction of DNA damage checkpoint protein Rad53 with chromatin assembly factor Asf1.

Emili A, Schieltz DM, Yates JR 3rd, Hartwell LH.

Mol Cell. 2001 Jan;7(1):13-20.


A novel multiple affinity purification tag and its use in identification of proteins associated with a cyclin-CDK complex.

Honey S, Schneider BL, Schieltz DM, Yates JR, Futcher B.

Nucleic Acids Res. 2001 Feb 15;29(4):E24.


Serine 727 phosphorylation and activation of cytosolic phospholipase A2 by MNK1-related protein kinases.

Hefner Y, Borsch-Haubold AG, Murakami M, Wilde JI, Pasquet S, Schieltz D, Ghomashchi F, Yates JR 3rd, Armstrong CG, Paterson A, Cohen P, Fukunaga R, Hunter T, Kudo I, Watson SP, Gelb MH.

J Biol Chem. 2000 Dec 1;275(48):37542-51.


Direct analysis of proteins in mixtures. Application to protein complexes.

Yates JR 3rd, Link AJ, Schieltz D.

Methods Mol Biol. 2000;146:17-26. Review. No abstract available.


Structural analysis of protein prenyl groups and associated C-terminal modifications.

Whitten ME, Yokoyama K, Schieltz D, Ghomashchi F, Lam D, Yates JR 3rd, Palczewski K, Gelb MH.

Methods Enzymol. 2000;316:436-51. No abstract available.


Identification and characterization of five new subunits of TRAPP.

Sacher M, Barrowman J, Schieltz D, Yates JR 3rd, Ferro-Novick S.

Eur J Cell Biol. 2000 Feb;79(2):71-80. Erratum in: Eur J Cell Biol. 2000 Jul;79(7):520.


The ADA complex is a distinct histone acetyltransferase complex in Saccharomyces cerevisiae.

Eberharter A, Sterner DE, Schieltz D, Hassan A, Yates JR 3rd, Berger SL, Workman JL.

Mol Cell Biol. 1999 Oct;19(10):6621-31.


Direct analysis of protein complexes using mass spectrometry.

Link AJ, Eng J, Schieltz DM, Carmack E, Mize GJ, Morris DR, Garvik BM, Yates JR 3rd.

Nat Biotechnol. 1999 Jul;17(7):676-82.


Mgm101p is a novel component of the mitochondrial nucleoid that binds DNA and is required for the repair of oxidatively damaged mitochondrial DNA.

Meeusen S, Tieu Q, Wong E, Weiss E, Schieltz D, Yates JR, Nunnari J.

J Cell Biol. 1999 Apr 19;145(2):291-304.


Preparing 2-D protein extracts from yeast.

Schieltz DM.

Methods Mol Biol. 1999;112:31-4. Review. No abstract available.


The ATM-related cofactor Tra1 is a component of the purified SAGA complex.

Grant PA, Schieltz D, Pray-Grant MG, Yates JR 3rd, Workman JL.

Mol Cell. 1998 Dec;2(6):863-7.


The septins are required for the mitosis-specific activation of the Gin4 kinase.

Carroll CW, Altman R, Schieltz D, Yates JR, Kellogg D.

J Cell Biol. 1998 Nov 2;143(3):709-17.


Tra1p is a component of the yeast Ada.Spt transcriptional regulatory complexes.

Saleh A, Schieltz D, Ting N, McMahon SB, Litchfield DW, Yates JR 3rd, Lees-Miller SP, Cole MD, Brandl CJ.

J Biol Chem. 1998 Oct 9;273(41):26559-65.


A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation.

Grant PA, Schieltz D, Pray-Grant MG, Steger DJ, Reese JC, Yates JR 3rd, Workman JL.

Cell. 1998 Jul 10;94(1):45-53.


TRAPP, a highly conserved novel complex on the cis-Golgi that mediates vesicle docking and fusion.

Sacher M, Jiang Y, Barrowman J, Scarpa A, Burston J, Zhang L, Schieltz D, Yates JR 3rd, Abeliovich H, Ferro-Novick S.

EMBO J. 1998 May 1;17(9):2494-503.


Direct analysis of protein mixtures by tandem mass spectrometry.

Yates JR 3rd, McCormack AL, Schieltz D, Carmack E, Link A.

J Protein Chem. 1997 Jul;16(5):495-7.


Direct analysis and identification of proteins in mixtures by LC/MS/MS and database searching at the low-femtomole level.

McCormack AL, Schieltz DM, Goode B, Yang S, Barnes G, Drubin D, Yates JR 3rd.

Anal Chem. 1997 Feb 15;69(4):767-76.


Future prospects for the analysis of complex biological systems using micro-column liquid chromatography-electrospray tandem mass spectrometry.

Yates JR 3rd, McCormack AL, Link AJ, Schieltz D, Eng J, Hays L.

Analyst. 1996 Jul;121(7):65R-76R. Review.


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