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Items: 1 to 50 of 107

1.

Tenomodulin regulates matrix remodeling of mouse tendon stem/progenitor cells in an ex vivo collagen I gel model.

Yin H, Caceres MD, Yan Z, Schieker M, Nerlich M, Docheva D.

Biochem Biophys Res Commun. 2019 May 14;512(4):691-697. doi: 10.1016/j.bbrc.2019.03.063. Epub 2019 Mar 25.

2.

A Perfusion Bioreactor System for Cell Seeding and Oxygen-Controlled Cultivation of Three-Dimensional Cell Cultures.

Schmid J, Schwarz S, Meier-Staude R, Sudhop S, Clausen-Schaumann H, Schieker M, Huber R.

Tissue Eng Part C Methods. 2018 Oct;24(10):585-595. doi: 10.1089/ten.TEC.2018.0204.

3.

In Vitro Comparison of 2D-Cell Culture and 3D-Cell Sheets of Scleraxis-Programmed Bone Marrow Derived Mesenchymal Stem Cells to Primary Tendon Stem/Progenitor Cells for Tendon Repair.

Hsieh CF, Yan Z, Schumann RG, Milz S, Pfeifer CG, Schieker M, Docheva D.

Int J Mol Sci. 2018 Aug 2;19(8). pii: E2272. doi: 10.3390/ijms19082272.

4.

IL-6, IL-1β, and TNF-α only in combination influence the osteoporotic phenotype in Crohn's patients via bone formation and bone resorption.

Blaschke M, Koepp R, Cortis J, Komrakova M, Schieker M, Hempel U, Siggelkow H.

Adv Clin Exp Med. 2018 Jan;27(1):45-56. doi: 10.17219/acem/67561.

5.

Correction: Viable adhered Staphylococcus aureus highly reduced on novel antimicrobial sutures using chlorhexidine and octenidine to avoid surgical site infection (SSI).

Obermeier A, Schneider J, Harrasser N, Tübel J, Mühlhofer H, Pförringer D, Deimling CV, Foehr P, Kiefel B, Krämer C, Stemberger A, Schieker M, Burgkart R, von Eisenhart-Rothe R.

PLoS One. 2018 Feb 15;13(2):e0193284. doi: 10.1371/journal.pone.0193284. eCollection 2018.

6.

Functionalized thermosensitive hydrogel combined with tendon stem/progenitor cells as injectable cell delivery carrier for tendon tissue engineering.

Yin H, Yan Z, Bauer RJ, Peng J, Schieker M, Nerlich M, Docheva D.

Biomed Mater. 2018 Mar 16;13(3):034107. doi: 10.1088/1748-605X/aaadd1.

PMID:
29417934
7.

Viable adhered Staphylococcus aureus highly reduced on novel antimicrobial sutures using chlorhexidine and octenidine to avoid surgical site infection (SSI).

Obermeier A, Schneider J, Harrasser N, Tübel J, Mühlhofer H, Pförringer D, Deimling CV, Foehr P, Kiefel B, Krämer C, Stemberger A, Schieker M, Burgkart R, von Eisenhart-Rothe R.

PLoS One. 2018 Jan 9;13(1):e0190912. doi: 10.1371/journal.pone.0190912. eCollection 2018. Erratum in: PLoS One. 2018 Feb 15;13(2):e0193284.

8.

Tenomodulin is essential for prevention of adipocyte accumulation and fibrovascular scar formation during early tendon healing.

Lin D, Alberton P, Caceres MD, Volkmer E, Schieker M, Docheva D.

Cell Death Dis. 2017 Oct 12;8(10):e3116. doi: 10.1038/cddis.2017.510.

9.

Mechanical and biological effects of infiltration with biopolymers on 3D printed tricalciumphosphate scaffolds.

Cornelsen M, Probst FA, Schwarz C, Burian E, Tröltzsch M, Otto S, Saller MM, Schieker M, Seitz H.

Dent Mater J. 2017 Sep 26;36(5):553-559. doi: 10.4012/dmj.2016-306. Epub 2017 Jul 26.

10.

Tenomodulin is Required for Tendon Endurance Running and Collagen I Fibril Adaptation to Mechanical Load.

Dex S, Alberton P, Willkomm L, Söllradl T, Bago S, Milz S, Shakibaei M, Ignatius A, Bloch W, Clausen-Schaumann H, Shukunami C, Schieker M, Docheva D.

EBioMedicine. 2017 Jun;20:240-254. doi: 10.1016/j.ebiom.2017.05.003. Epub 2017 May 5.

11.

Effect of hypoxia on the proliferation of porcine bone marrow-derived mesenchymal stem cells and adipose-derived mesenchymal stem cells in 2- and 3-dimensional culture.

Burian E, Probst F, Palla B, Riedel C, Saller MM, Cornelsen M, König F, Schieker M, Otto S.

J Craniomaxillofac Surg. 2017 Mar;45(3):414-419. doi: 10.1016/j.jcms.2016.12.014. Epub 2016 Dec 20.

PMID:
28110999
12.

Periodontal ligament cells as alternative source for cell-based therapy of tendon injuries: in vivo study of full-size Achilles tendon defect in a rat model.

Hsieh CF, Alberton P, Loffredo-Verde E, Volkmer E, Pietschmann M, Müller PE, Schieker M, Docheva D.

Eur Cell Mater. 2016 Oct 20;32:228-240.

13.

Oxygen mapping: Probing a novel seeding strategy for bone tissue engineering.

Westphal I, Jedelhauser C, Liebsch G, Wilhelmi A, Aszodi A, Schieker M.

Biotechnol Bioeng. 2017 Apr;114(4):894-902. doi: 10.1002/bit.26202. Epub 2016 Nov 17.

14.

Value of a coordinated management of osteoporosis via Fracture Liaison Service for the treatment of orthogeriatric patients.

Schray D, Neuerburg C, Stein J, Gosch M, Schieker M, Böcker W, Kammerlander C.

Eur J Trauma Emerg Surg. 2016 Oct;42(5):559-564. Epub 2016 Jul 25.

PMID:
27458065
15.

Scaffold-free Scleraxis-programmed tendon progenitors aid in significantly enhanced repair of full-size Achilles tendon rupture.

Hsieh CF, Alberton P, Loffredo-Verde E, Volkmer E, Pietschmann M, Müller P, Schieker M, Docheva D.

Nanomedicine (Lond). 2016 May;11(9):1153-67. doi: 10.2217/nnm.16.34. Epub 2016 Apr 13.

16.

Efficacy and safety of extracorporeal shock wave therapy for orthopedic conditions: a systematic review on studies listed in the PEDro database.

Schmitz C, Császár NB, Milz S, Schieker M, Maffulli N, Rompe JD, Furia JP.

Br Med Bull. 2015;116:115-38. doi: 10.1093/bmb/ldv047. Epub 2015 Nov 18. Review.

17.

Structural and mechanical properties of the proliferative zone of the developing murine growth plate cartilage assessed by atomic force microscopy.

Prein C, Warmbold N, Farkas Z, Schieker M, Aszodi A, Clausen-Schaumann H.

Matrix Biol. 2016 Mar;50:1-15. doi: 10.1016/j.matbio.2015.10.001. Epub 2015 Oct 8.

18.

In vitro evaluation of novel antimicrobial coatings for surgical sutures using octenidine.

Obermeier A, Schneider J, Föhr P, Wehner S, Kühn KD, Stemberger A, Schieker M, Burgkart R.

BMC Microbiol. 2015 Sep 24;15:186. doi: 10.1186/s12866-015-0523-4.

19.

Mechanical stimulation of human tendon stem/progenitor cells results in upregulation of matrix proteins, integrins and MMPs, and activation of p38 and ERK1/2 kinases.

Popov C, Burggraf M, Kreja L, Ignatius A, Schieker M, Docheva D.

BMC Mol Biol. 2015 Mar 13;16:6. doi: 10.1186/s12867-015-0036-6.

20.

Loss of tenomodulin results in reduced self-renewal and augmented senescence of tendon stem/progenitor cells.

Alberton P, Dex S, Popov C, Shukunami C, Schieker M, Docheva D.

Stem Cells Dev. 2015 Mar 1;24(5):597-609. doi: 10.1089/scd.2014.0314. Epub 2014 Dec 10.

21.

Influence of osteogenic stimulation and VEGF treatment on in vivo bone formation in hMSC-seeded cancellous bone scaffolds.

Lenze U, Pohlig F, Seitz S, Ern C, Milz S, Docheva D, Schieker M.

BMC Musculoskelet Disord. 2014 Oct 16;15:350. doi: 10.1186/1471-2474-15-350.

22.

Mesenchymal stem cells from osteoporotic patients reveal reduced migration and invasion upon stimulation with BMP-2 or BMP-7.

Haasters F, Docheva D, Gassner C, Popov C, Böcker W, Mutschler W, Schieker M, Prall WC.

Biochem Biophys Res Commun. 2014 Sep 12;452(1):118-23. doi: 10.1016/j.bbrc.2014.08.055. Epub 2014 Aug 21.

23.

Sox2 is a potent inhibitor of osteogenic and adipogenic differentiation in human mesenchymal stem cells.

Schönitzer V, Wirtz R, Ulrich V, Berger T, Karl A, Mutschler W, Schieker M, Böcker W.

Cell Reprogram. 2014 Oct;16(5):355-65. doi: 10.1089/cell.2014.0006. Epub 2014 Aug 15.

PMID:
25127284
24.

In vivo mesenchymal stem cell tracking with PET using the dopamine type 2 receptor and 18F-fallypride.

Schönitzer V, Haasters F, Käsbauer S, Ulrich V, Mille E, Gildehaus FJ, Carlsen J, Pape M, Beck R, Delker A, Böning G, Mutschler W, Böcker W, Schieker M, Bartenstein P.

J Nucl Med. 2014 Aug;55(8):1342-7. doi: 10.2967/jnumed.113.134775. Epub 2014 Jul 14.

25.

Aged human mesenchymal stem cells: the duration of bone morphogenetic protein-2 stimulation determines induction or inhibition of osteogenic differentiation.

Heggebö J, Haasters F, Polzer H, Schwarz C, Saller MM, Mutschler W, Schieker M, Prall WC.

Orthop Rev (Pavia). 2014 Jun 3;6(2):5242. doi: 10.4081/or.2014.5242. eCollection 2014 Apr 22.

26.

Novel high efficient coatings for anti-microbial surgical sutures using chlorhexidine in fatty acid slow-release carrier systems.

Obermeier A, Schneider J, Wehner S, Matl FD, Schieker M, von Eisenhart-Rothe R, Stemberger A, Burgkart R.

PLoS One. 2014 Jul 1;9(7):e101426. doi: 10.1371/journal.pone.0101426. eCollection 2014.

27.

MicroRNA-23a mediates post-transcriptional regulation of CXCL12 in bone marrow stromal cells.

Arabanian LS, Fierro FA, Stölzel F, Heder C, Poitz DM, Strasser RH, Wobus M, Borhäuser M, Ferrer RA, Platzbecker U, Schieker M, Docheva D, Ehninger G, Illmer T.

Haematologica. 2014 Jun;99(6):997-1005. doi: 10.3324/haematol.2013.097675. Epub 2014 Feb 28.

28.

[Prevalence and management of osteoporosis in trauma surgery. Implementation of national guidelines during inpatient fracture treatment].

Haasters F, Prall WC, Himmler M, Polzer H, Schieker M, Mutschler W.

Unfallchirurg. 2015 Feb;118(2):138-45. doi: 10.1007/s00113-013-2500-4. German.

PMID:
24414093
29.

MiR-134-mediated β1 integrin expression and function in mesenchymal stem cells.

Poitz DM, Stölzel F, Arabanian L, Friedrichs J, Docheva D, Schieker M, Fierro FA, Platzbecker U, Ordemann R, Werner C, Bornhäuser M, Strasser RH, Ehninger G, Illmer T.

Biochim Biophys Acta. 2013 Dec;1833(12):3396-3404. doi: 10.1016/j.bbamcr.2013.10.003. Epub 2013 Oct 15.

30.

Mesenchymal stem cells from osteoporotic patients feature impaired signal transduction but sustained osteoinduction in response to BMP-2 stimulation.

Prall WC, Haasters F, Heggebö J, Polzer H, Schwarz C, Gassner C, Grote S, Anz D, Jäger M, Mutschler W, Schieker M.

Biochem Biophys Res Commun. 2013 Nov 1;440(4):617-22. doi: 10.1016/j.bbrc.2013.09.114. Epub 2013 Oct 5.

PMID:
24099772
31.

[Osteoid osteoma of the talus: a rare cause for pain in the ankle joint].

Polzer H, Polzer S, Schieker M, Mutschler W, Regauer M.

Unfallchirurg. 2014 Jul;117(7):666-9. doi: 10.1007/s00113-013-2481-3. German.

PMID:
23949192
32.

Uncovering the cellular and molecular changes in tendon stem/progenitor cells attributed to tendon aging and degeneration.

Kohler J, Popov C, Klotz B, Alberton P, Prall WC, Haasters F, Müller-Deubert S, Ebert R, Klein-Hitpass L, Jakob F, Schieker M, Docheva D.

Aging Cell. 2013 Dec;12(6):988-99. doi: 10.1111/acel.12124. Epub 2013 Jul 22.

33.

Overexpression of dnIKK in mesenchymal stem cells leads to increased migration and decreased invasion upon TNFα stimulation.

Haasters F, Prall WC, Westphal I, Böcker W, Padula D, Mutschler W, Docheva D, Schieker M.

Biochem Biophys Res Commun. 2013 Jun 28;436(2):265-70. doi: 10.1016/j.bbrc.2013.05.091. Epub 2013 Jun 4.

PMID:
23743204
34.

Poloxamer-based hydrogels hardening at body core temperature as carriers for cell based therapies: in vitro and in vivo analysis.

Volkmer E, Leicht U, Moritz M, Schwarz C, Wiese H, Milz S, Matthias P, Schloegl W, Friess W, Goettlinger M, Augat P, Schieker M.

J Mater Sci Mater Med. 2013 Sep;24(9):2223-34. doi: 10.1007/s10856-013-4966-6. Epub 2013 May 28.

PMID:
23712537
35.

Comparison of different strategies for in vivo seeding of prevascularized scaffolds.

Polzer H, Volkmer E, Saller MM, Prall WC, Haasters F, Drosse I, Wilhelmi A, Mutschler W, Schieker M.

Tissue Eng Part C Methods. 2014 Jan;20(1):11-8. doi: 10.1089/ten.TEC.2012.0740. Epub 2013 May 21.

PMID:
23594127
36.

Probing the interaction forces of prostate cancer cells with collagen I and bone marrow derived stem cells on the single cell level.

Sariisik E, Docheva D, Padula D, Popov C, Opfer J, Schieker M, Clausen-Schaumann H, Benoit M.

PLoS One. 2013;8(3):e57706. doi: 10.1371/journal.pone.0057706. Epub 2013 Mar 5. Erratum in: PLoS One. 2013.8(10). doi:10.1371/annotation/d7f2081e-8756-4253-a066-7fb084cd0759.

37.

Study protocol: the effect of whole body vibration on acute unilateral unstable lateral ankle sprain- a biphasic randomized controlled trial.

Baumbach SF, Fasser M, Polzer H, Sieb M, Regauer M, Mutschler W, Schieker M, Blauth M.

BMC Musculoskelet Disord. 2013 Jan 14;14:22. doi: 10.1186/1471-2474-14-22.

38.

Polypropylene meshes coated with a polysaccharide based bioadhesive for intra-abdominal mesh fixation in a rabbit model.

Ladurner R, Drosse I, Chiapponi C, Bürklein D, Jansson V, Kokott A, Hoffmann B, Ziegler G, Mustchler W, Mussack T, Schieker M.

Surg Endosc. 2013 Jun;27(6):1991-6. doi: 10.1007/s00464-012-2699-0. Epub 2013 Jan 9.

PMID:
23299133
39.

Comparison of tenocytes and mesenchymal stem cells seeded on biodegradable scaffolds in a full-size tendon defect model.

Pietschmann MF, Frankewycz B, Schmitz P, Docheva D, Sievers B, Jansson V, Schieker M, Müller PE.

J Mater Sci Mater Med. 2013 Jan;24(1):211-20. doi: 10.1007/s10856-012-4791-3. Epub 2012 Oct 23.

PMID:
23090834
40.

Porosity and mechanically optimized PLGA based in situ hardening systems.

Schloegl W, Marschall V, Witting MY, Volkmer E, Drosse I, Leicht U, Schieker M, Wiggenhorn M, Schaubhut F, Zahler S, Friess W.

Eur J Pharm Biopharm. 2012 Nov;82(3):554-62. doi: 10.1016/j.ejpb.2012.08.006. Epub 2012 Aug 28.

PMID:
22947486
41.

Collagen type I and decorin expression in tenocytes depend on the cell isolation method.

Wagenhäuser MU, Pietschmann MF, Sievers B, Docheva D, Schieker M, Jansson V, Müller PE.

BMC Musculoskelet Disord. 2012 Aug 8;13:140. doi: 10.1186/1471-2474-13-140.

42.

Overcoming hypoxia in 3D culture systems for tissue engineering of bone in vitro using an automated, oxygen-triggered feedback loop.

Volkmer E, Otto S, Polzer H, Saller M, Trappendreher D, Zagar D, Hamisch S, Ziegler G, Wilhelmi A, Mutschler W, Schieker M.

J Mater Sci Mater Med. 2012 Nov;23(11):2793-801. doi: 10.1007/s10856-012-4725-0. Epub 2012 Jul 29.

PMID:
22843167
43.

Increased stemness and migration of human mesenchymal stem cells in hypoxia is associated with altered integrin expression.

Saller MM, Prall WC, Docheva D, Schönitzer V, Popov T, Anz D, Clausen-Schaumann H, Mutschler W, Volkmer E, Schieker M, Polzer H.

Biochem Biophys Res Commun. 2012 Jun 29;423(2):379-85. doi: 10.1016/j.bbrc.2012.05.134. Epub 2012 Jun 1.

PMID:
22664105
44.

[Alterations of cell phenotype in Dupuytren's disease--an in vitro analysis].

Docheva D, Vaerst B, Deiler S, Giunta RE, Schieker M, Volkmer E.

Handchir Mikrochir Plast Chir. 2012 Apr;44(2):59-66. doi: 10.1055/s-0032-1309025. Epub 2012 Apr 11. German.

PMID:
22495955
45.

First inducible transgene expression in porcine large animal models.

Klymiuk N, Böcker W, Schönitzer V, Bähr A, Radic T, Fröhlich T, Wünsch A, Keßler B, Kurome M, Schilling E, Herbach N, Wanke R, Nagashima H, Mutschler W, Arnold GJ, Schwinzer R, Schieker M, Wolf E.

FASEB J. 2012 Mar;26(3):1086-99. doi: 10.1096/fj.11-185041. Epub 2011 Dec 1.

PMID:
22138035
46.

Residual transglutaminase in collagen - effects, detection, quantification, and removal.

Schloegl W, Klein A, Fürst R, Leicht U, Volkmer E, Schieker M, Jus S, Guebitz GM, Stachel I, Meyer M, Wiggenhorn M, Friess W.

Eur J Pharm Biopharm. 2012 Feb;80(2):282-8. doi: 10.1016/j.ejpb.2011.10.018. Epub 2011 Nov 4.

PMID:
22079174
47.

Molecular cloning and functional characterization of the porcine extracellular domain of Receptor Activator of NF-κB Ligand (sRANKL).

Böcker W, Radic T, Schönitzer V, Haasters F, Mutschler W, Schieker M.

Gene. 2012 Jan 15;492(1):296-304. doi: 10.1016/j.gene.2011.08.008. Epub 2011 Sep 16.

PMID:
22062001
48.

In situ guided tissue regeneration in musculoskeletal diseases and aging : Implementing pathology into tailored tissue engineering strategies.

Jakob F, Ebert R, Rudert M, Nöth U, Walles H, Docheva D, Schieker M, Meinel L, Groll J.

Cell Tissue Res. 2012 Mar;347(3):725-35. doi: 10.1007/s00441-011-1237-z. Epub 2011 Oct 20. Review.

49.

Conversion of human bone marrow-derived mesenchymal stem cells into tendon progenitor cells by ectopic expression of scleraxis.

Alberton P, Popov C, Prägert M, Kohler J, Shukunami C, Schieker M, Docheva D.

Stem Cells Dev. 2012 Apr 10;21(6):846-58. doi: 10.1089/scd.2011.0150. Epub 2011 Oct 11.

50.

Long-term detection of fluorescently labeled human mesenchymal stem cell in vitro and in vivo by semi-automated microscopy.

Polzer H, Volkmer E, Saller MM, Prall WC, Haasters F, Drosse I, Anz D, Mutschler W, Schieker M.

Tissue Eng Part C Methods. 2012 Feb;18(2):156-65. doi: 10.1089/ten.TEC.2011.0275. Epub 2011 Dec 13.

PMID:
21951128

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