Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 117


Insights into the assembly and activation of the microtubule nucleator γ-TuRC.

Liu P, Zupa E, Neuner A, Böhler A, Loerke J, Flemming D, Ruppert T, Rudack T, Peter C, Spahn C, Gruss OJ, Pfeffer S, Schiebel E.

Nature. 2019 Dec 19. doi: 10.1038/s41586-019-1896-6. [Epub ahead of print]


The balance between KIFC3 and EG5 tetrameric kinesins controls the onset of mitotic spindle assembly.

Hata S, Pastor Peidro A, Panic M, Liu P, Atorino E, Funaya C, Jäkle U, Pereira G, Schiebel E.

Nat Cell Biol. 2019 Sep;21(9):1138-1151. doi: 10.1038/s41556-019-0382-6. Epub 2019 Sep 2.


The human phosphatase CDC14A modulates primary cilium length by regulating centrosomal actin nucleation.

Uddin B, Partscht P, Chen NP, Neuner A, Weiß M, Hardt R, Jafarpour A, Heßling B, Ruppert T, Lorenz H, Pereira G, Schiebel E.

EMBO Rep. 2019 Jan;20(1). pii: e46544. doi: 10.15252/embr.201846544. Epub 2018 Nov 22.


The microtubule polymerase Stu2 promotes oligomerization of the γ-TuSC for cytoplasmic microtubule nucleation.

Gunzelmann J, Rüthnick D, Lin TC, Zhang W, Neuner A, Jäkle U, Schiebel E.

Elife. 2018 Sep 17;7. pii: e39932. doi: 10.7554/eLife.39932.


Electrochemical, Spectroelectrochemical, Mößbauer, and EPR Spectroscopic Studies on Ferrocenyl-Substituted Tritylium Dyes.

Oßwald S, Casper LA, Anders P, Schiebel E, Demeshko S, Winter RF.

Chemistry. 2018 Aug 27;24(48):12524-12538. doi: 10.1002/chem.201802364. Epub 2018 Jul 26.


Duplication and Nuclear Envelope Insertion of the Yeast Microtubule Organizing Centre, the Spindle Pole Body.

Rüthnick D, Schiebel E.

Cells. 2018 May 10;7(5). pii: E42. doi: 10.3390/cells7050042. Review.


MISP regulates the IQGAP1/Cdc42 complex to collectively orchestrate spindle orientation and mitotic progression.

Vodicska B, Cerikan B, Schiebel E, Hoffmann I.

Sci Rep. 2018 Apr 20;8(1):6330. doi: 10.1038/s41598-018-24682-8.


STED nanoscopy of the centrosome linker reveals a CEP68-organized, periodic rootletin network anchored to a C-Nap1 ring at centrioles.

Vlijm R, Li X, Panic M, Rüthnick D, Hata S, Herrmannsdörfer F, Kuner T, Heilemann M, Engelhardt J, Hell SW, Schiebel E.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2246-E2253. doi: 10.1073/pnas.1716840115. Epub 2018 Feb 20.


Brr6 and Brl1 locate to nuclear pore complex assembly sites to promote their biogenesis.

Zhang W, Neuner A, Rüthnick D, Sachsenheimer T, Lüchtenborg C, Brügger B, Schiebel E.

J Cell Biol. 2018 Mar 5;217(3):877-894. doi: 10.1083/jcb.201706024. Epub 2018 Feb 9.


Polo-like kinase Cdc5 regulates Spc72 recruitment to spindle pole body in the methylotrophic yeast Ogataea polymorpha.

Maekawa H, Neuner A, Rüthnick D, Schiebel E, Pereira G, Kaneko Y.

Elife. 2017 Aug 30;6. pii: e24340. doi: 10.7554/eLife.24340.


Characterization of spindle pole body duplication reveals a regulatory role for nuclear pore complexes.

Rüthnick D, Neuner A, Dietrich F, Kirrmaier D, Engel U, Knop M, Schiebel E.

J Cell Biol. 2017 Aug 7;216(8):2425-2442. doi: 10.1083/jcb.201612129. Epub 2017 Jun 28.


Human phosphatase CDC14A regulates actin organization through dephosphorylation of epithelial protein lost in neoplasm.

Chen NP, Uddin B, Hardt R, Ding W, Panic M, Lucibello I, Kammerer P, Ruppert T, Schiebel E.

Proc Natl Acad Sci U S A. 2017 May 16;114(20):5201-5206. doi: 10.1073/pnas.1619356114. Epub 2017 May 2.


A ternary membrane protein complex anchors the spindle pole body in the nuclear envelope in budding yeast.

Kupke T, Malsam J, Schiebel E.

J Biol Chem. 2017 May 19;292(20):8447-8458. doi: 10.1074/jbc.M117.780601. Epub 2017 Mar 29.


Mechanism of cell-intrinsic adaptation to Adams-Oliver Syndrome gene DOCK6 disruption highlights ubiquitin-like modifier ISG15 as a regulator of RHO GTPases.

Cerikan B, Schiebel E.

Small GTPases. 2019 May;10(3):210-217. doi: 10.1080/21541248.2017.1297882. Epub 2017 Mar 13.


MOZART1 and γ-tubulin complex receptors are both required to turn γ-TuSC into an active microtubule nucleation template.

Lin TC, Neuner A, Flemming D, Liu P, Chinen T, Jäkle U, Arkowitz R, Schiebel E.

J Cell Biol. 2016 Dec 19;215(6):823-840. Epub 2016 Dec 5.


DOCK6 inactivation highlights ISGylation as RHO-GTPase balancer.

Cerikan B, Schiebel E.

Cell Cycle. 2017 Feb 16;16(4):304-305. doi: 10.1080/15384101.2016.1256153. Epub 2016 Nov 10. No abstract available.


Cell-Intrinsic Adaptation Arising from Chronic Ablation of a Key Rho GTPase Regulator.

Cerikan B, Shaheen R, Colo GP, Gläßer C, Hata S, Knobeloch KP, Alkuraya FS, Fässler R, Schiebel E.

Dev Cell. 2016 Oct 10;39(1):28-43. doi: 10.1016/j.devcel.2016.08.020. Epub 2016 Sep 29.


Mitotic exit: Determining the PP2A dephosphorylation program.

Pereira G, Schiebel E.

J Cell Biol. 2016 Aug 29;214(5):499-501. doi: 10.1083/jcb.201608019. Epub 2016 Aug 22.


Proximity mapping of human separase by the BioID approach.

Agircan FG, Hata S, Nussbaum-Krammer C, Atorino E, Schiebel E.

Biochem Biophys Res Commun. 2016 Sep 16;478(2):656-62. doi: 10.1016/j.bbrc.2016.08.002. Epub 2016 Aug 3.


Redox regulation of SUMO enzymes is required for ATM activity and survival in oxidative stress.

Stankovic-Valentin N, Drzewicka K, König C, Schiebel E, Melchior F.

EMBO J. 2016 Jun 15;35(12):1312-29. doi: 10.15252/embj.201593404. Epub 2016 May 12.


Duplication of the Yeast Spindle Pole Body Once per Cell Cycle.

Rüthnick D, Schiebel E.

Mol Cell Biol. 2016 Apr 15;36(9):1324-31. doi: 10.1128/MCB.00048-16. Print 2016 May. Review.


Human phosphatase CDC14A is recruited to the cell leading edge to regulate cell migration and adhesion.

Chen NP, Uddin B, Voit R, Schiebel E.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):990-5. doi: 10.1073/pnas.1515605113. Epub 2016 Jan 8.


Genome editing through large insertion leads to the skipping of targeted exon.

Uddin B, Chen NP, Panic M, Schiebel E.

BMC Genomics. 2015 Dec 21;16:1082. doi: 10.1186/s12864-015-2284-8.


The γ-tubulin-specific inhibitor gatastatin reveals temporal requirements of microtubule nucleation during the cell cycle.

Chinen T, Liu P, Shioda S, Pagel J, Cerikan B, Lin TC, Gruss O, Hayashi Y, Takeno H, Shima T, Okada Y, Hayakawa I, Hayashi Y, Kigoshi H, Usui T, Schiebel E.

Nat Commun. 2015 Oct 27;6:8722. doi: 10.1038/ncomms9722.


Kar1 binding to Sfi1 C-terminal regions anchors the SPB bridge to the nuclear envelope.

Seybold C, Elserafy M, Rüthnick D, Ozboyaci M, Neuner A, Flottmann B, Heilemann M, Wade RC, Schiebel E.

J Cell Biol. 2015 Jun 22;209(6):843-61. doi: 10.1083/jcb.201412050. Epub 2015 Jun 15.


The centrosomal linker and microtubules provide dual levels of spatial coordination of centrosomes.

Panic M, Hata S, Neuner A, Schiebel E.

PLoS Genet. 2015 May 22;11(5):e1005243. doi: 10.1371/journal.pgen.1005243. eCollection 2015 May.


Compartment-specific aggregases direct distinct nuclear and cytoplasmic aggregate deposition.

Miller SB, Ho CT, Winkler J, Khokhrina M, Neuner A, Mohamed MY, Guilbride DL, Richter K, Lisby M, Schiebel E, Mogk A, Bukau B.

EMBO J. 2015 Mar 12;34(6):778-97. doi: 10.15252/embj.201489524. Epub 2015 Feb 11.


Targeting of γ-tubulin complexes to microtubule organizing centers: conservation and divergence.

Lin TC, Neuner A, Schiebel E.

Trends Cell Biol. 2015 May;25(5):296-307. doi: 10.1016/j.tcb.2014.12.002. Epub 2014 Dec 24. Review.


Sensors at centrosomes reveal determinants of local separase activity.

Agircan FG, Schiebel E.

PLoS Genet. 2014 Oct 9;10(10):e1004672. doi: 10.1371/journal.pgen.1004672. eCollection 2014 Oct.


Separate to operate: control of centrosome positioning and separation.

Agircan FG, Schiebel E, Mardin BR.

Philos Trans R Soc Lond B Biol Sci. 2014 Sep 5;369(1650). pii: 20130461. doi: 10.1098/rstb.2013.0461. Review.


Molecular mechanisms that restrict yeast centrosome duplication to one event per cell cycle.

Elserafy M, Šarić M, Neuner A, Lin TC, Zhang W, Seybold C, Sivashanmugam L, Schiebel E.

Curr Biol. 2014 Jul 7;24(13):1456-66. doi: 10.1016/j.cub.2014.05.032. Epub 2014 Jun 19.


Cell-cycle dependent phosphorylation of yeast pericentrin regulates γ-TuSC-mediated microtubule nucleation.

Lin TC, Neuner A, Schlosser YT, Scharf AN, Weber L, Schiebel E.

Elife. 2014 Apr 30;3:e02208. doi: 10.7554/eLife.02208.


GTP regulates the microtubule nucleation activity of γ-tubulin.

Gombos L, Neuner A, Berynskyy M, Fava LL, Wade RC, Sachse C, Schiebel E.

Nat Cell Biol. 2013 Nov;15(11):1317-27. doi: 10.1038/ncb2863. Epub 2013 Oct 27.


Spindle pole bodies.

Seybold C, Schiebel E.

Curr Biol. 2013 Oct 7;23(19):R858-60. doi: 10.1016/j.cub.2013.07.024. No abstract available.


EGF-induced centrosome separation promotes mitotic progression and cell survival.

Mardin BR, Isokane M, Cosenza MR, Krämer A, Ellenberg J, Fry AM, Schiebel E.

Dev Cell. 2013 May 13;25(3):229-40. doi: 10.1016/j.devcel.2013.03.012. Epub 2013 May 2.


Tandem fluorescent protein timers for in vivo analysis of protein dynamics.

Khmelinskii A, Keller PJ, Bartosik A, Meurer M, Barry JD, Mardin BR, Kaufmann A, Trautmann S, Wachsmuth M, Pereira G, Huber W, Schiebel E, Knop M.

Nat Biotechnol. 2012 Jun 24;30(7):708-14. doi: 10.1038/nbt.2281.


An extended γ-tubulin ring functions as a stable platform in microtubule nucleation.

Erlemann S, Neuner A, Gombos L, Gibeaux R, Antony C, Schiebel E.

J Cell Biol. 2012 Apr 2;197(1):59-74. doi: 10.1083/jcb.201111123.


Breaking the ties that bind: new advances in centrosome biology.

Mardin BR, Schiebel E.

J Cell Biol. 2012 Apr 2;197(1):11-8. doi: 10.1083/jcb.201108006. Review.


Human Mob1 proteins are required for cytokinesis by controlling microtubule stability.

Florindo C, Perdigão J, Fesquet D, Schiebel E, Pines J, Tavares AA.

J Cell Sci. 2012 Jul 1;125(Pt 13):3085-90. doi: 10.1242/jcs.097147. Epub 2012 Mar 27.


The CENP-A chaperone Scm3 becomes enriched at kinetochores in anaphase independently of CENP-A incorporation.

Luconi L, Araki Y, Erlemann S, Schiebel E.

Cell Cycle. 2011 Oct 1;10(19):3369-78. doi: 10.4161/cc.10.19.17663. Epub 2011 Oct 1.


Targeting of Nbp1 to the inner nuclear membrane is essential for spindle pole body duplication.

Kupke T, Di Cecco L, Müller HM, Neuner A, Adolf F, Wieland F, Nickel W, Schiebel E.

EMBO J. 2011 Jul 22;30(16):3337-52. doi: 10.1038/emboj.2011.242.


Plk1 controls the Nek2A-PP1γ antagonism in centrosome disjunction.

Mardin BR, Agircan FG, Lange C, Schiebel E.

Curr Biol. 2011 Jul 12;21(13):1145-51. doi: 10.1016/j.cub.2011.05.047. Epub 2011 Jun 30.


Phosphorylation of the yeast γ-tubulin Tub4 regulates microtubule function.

Lin TC, Gombos L, Neuner A, Sebastian D, Olsen JV, Hrle A, Benda C, Schiebel E.

PLoS One. 2011 May 5;6(5):e19700. doi: 10.1371/journal.pone.0019700.


Directional switching of the kinesin Cin8 through motor coupling.

Roostalu J, Hentrich C, Bieling P, Telley IA, Schiebel E, Surrey T.

Science. 2011 Apr 1;332(6025):94-9. doi: 10.1126/science.1199945. Epub 2011 Feb 24.


Artificial tethering to nuclear pores promotes partitioning of extrachromosomal DNA during yeast asymmetric cell division.

Khmelinskii A, Meurer M, Knop M, Schiebel E.

Curr Biol. 2011 Jan 11;21(1):R17-8. doi: 10.1016/j.cub.2010.11.034.


Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction.

Mardin BR, Lange C, Baxter JE, Hardy T, Scholz SR, Fry AM, Schiebel E.

Nat Cell Biol. 2010 Dec;12(12):1166-76. doi: 10.1038/ncb2120. Epub 2010 Nov 14.


Cdc14: a highly conserved family of phosphatases with non-conserved functions?

Mocciaro A, Schiebel E.

J Cell Sci. 2010 Sep 1;123(Pt 17):2867-76. doi: 10.1242/jcs.074815. Review.


Segregation of yeast nuclear pores.

Khmelinskii A, Keller PJ, Lorenz H, Schiebel E, Knop M.

Nature. 2010 Jul 22;466(7305):E1. doi: 10.1038/nature09255.


Vertebrate cells genetically deficient for Cdc14A or Cdc14B retain DNA damage checkpoint proficiency but are impaired in DNA repair.

Mocciaro A, Berdougo E, Zeng K, Black E, Vagnarelli P, Earnshaw W, Gillespie D, Jallepalli P, Schiebel E.

J Cell Biol. 2010 May 17;189(4):631-9. doi: 10.1083/jcb.200910057.


Cell cycle control of spindle elongation.

Roostalu J, Schiebel E, Khmelinskii A.

Cell Cycle. 2010 Mar 15;9(6):1084-90. Epub 2010 Mar 15. Review.


Supplemental Content

Loading ...
Support Center