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MRI-derived radiomics: methodology and clinical applications in the field of pelvic oncology.

Schick U, Lucia F, Dissaux G, Visvikis D, Badic B, Masson I, Pradier O, Bourbonne V, Hatt M.

Br J Radiol. 2019 Oct 10:20190105. doi: 10.1259/bjr.20190105. [Epub ahead of print]


Radiotherapy mucositis in head and neck cancer: prevention by low-energy surface laser.

Bourbonne V, Otz J, Bensadoun RJ, Dissaux G, Lucia F, Leclere JC, Pradier O, Schick U.

BMJ Support Palliat Care. 2019 Sep 16. pii: bmjspcare-2019-001851. doi: 10.1136/bmjspcare-2019-001851. [Epub ahead of print]


MRI-Derived Radiomics to Guide Post-operative Management for High-Risk Prostate Cancer.

Bourbonne V, Vallières M, Lucia F, Doucet L, Visvikis D, Tissot V, Pradier O, Hatt M, Schick U.

Front Oncol. 2019 Aug 27;9:807. doi: 10.3389/fonc.2019.00807. eCollection 2019.


Cancer of the oesophagus and lymph nodes management in the neoadjuvant or definitive radiochemotherapy setting.

Bourbonné V, Pradier O, Schick U, Servagi-Vernat S.

Cancer Radiother. 2019 Oct;23(6-7):682-687. doi: 10.1016/j.canrad.2019.07.130. Epub 2019 Sep 3. Review.


Radiomics: Data Are Also Images.

Hatt M, Le Rest CC, Tixier F, Badic B, Schick U, Visvikis D.

J Nucl Med. 2019 Sep;60(Suppl 2):38S-44S. doi: 10.2967/jnumed.118.220582.


Multicentric validation of radiomics findings: challenges and opportunities.

Hatt M, Lucia F, Schick U, Visvikis D.

EBioMedicine. 2019 Sep;47:20-21. doi: 10.1016/j.ebiom.2019.08.054. Epub 2019 Aug 29. No abstract available.


Prospective four years of evaluation of erectile function after low-dose-rate prostate brachytherapy using baseline IIEF-5 > 16.

Schoentgen N, Marolleau J, Delage F, Coquet JB, Fourcade A, Callerot P, Serey-Eiffel S, Malhaire JP, Pradier O, Schick U, Fournier G, Valeri A.

J Contemp Brachytherapy. 2019 Jun;11(3):195-200. doi: 10.5114/jcb.2019.85793. Epub 2019 Jun 28.


Foci of Programmed Cell Death-Ligand 1 (PD-L1)-positive Tumor Areas With Tumor-infiltrating Leukocytes (TILs) Evocative of a PD-1/PD-L1-related Adaptive Immune Resistance are Frequent in Merkel Cell Carcinoma.

Bénigni P, Guénolé M, Bonsang B, Marcorelles P, Schick U, Uguen A.

Appl Immunohistochem Mol Morphol. 2019 Jul 23. doi: 10.1097/PAI.0000000000000792. [Epub ahead of print]


Prediction of response to immune checkpoint inhibitor therapy using 18F-FDG PET/CT in patients with melanoma.

Amrane K, Le Goupil D, Quere G, Delcroix O, Gouva S, Schick U, Salaun PY, Abgral R, Alavi Z, Keromnes N, Querellou S.

Medicine (Baltimore). 2019 Jul;98(29):e16417. doi: 10.1097/MD.0000000000016417.


PD-L1 Copy Number Variation Does Not Correlate With PD-L1 Expression or Response to Anti-PD-1 Immunotherapy In Patients With Advanced Melanomas.

Pérottet J, Le Goff E, Legoupil D, Quéré G, Schick U, Marcorelles P, Uguen A.

Appl Immunohistochem Mol Morphol. 2019 Jul 18. doi: 10.1097/PAI.0000000000000712. [Epub ahead of print]


Brain invasion in meningiomas: does surgical sampling impact specimen characteristics and histology?

Timme M, Thomas C, Spille DC, Stummer W, Ebel H, Ewelt C, Hans FJ, Schick U, Puchner M, Wildförster U, Bruns B, Trost HA, Holling M, Grauer O, Hess K, Brokinkel B.

Neurosurg Rev. 2019 Jun 3. doi: 10.1007/s10143-019-01125-0. [Epub ahead of print]


Low-level laser therapy in treatment of chemoradiotherapy-induced mucositis in head and neck cancer: results of a randomised, triple blind, multicentre phase III trial.

Legouté F, Bensadoun RJ, Seegers V, Pointreau Y, Caron D, Lang P, Prévost A, Martin L, Schick U, Morvant B, Capitain O, Calais G, Jadaud E.

Radiat Oncol. 2019 May 22;14(1):83. doi: 10.1186/s13014-019-1292-2.


Inter-observer and segmentation method variability of textural analysis in pre-therapeutic FDG PET/CT in head and neck cancer.

Guezennec C, Bourhis D, Orlhac F, Robin P, Corre JB, Delcroix O, Gobel Y, Schick U, Salaün PY, Abgral R.

PLoS One. 2019 Mar 28;14(3):e0214299. doi: 10.1371/journal.pone.0214299. eCollection 2019.


Diagnostic value of PET textural indices for malignancy of FDG-avid adrenal lesions.

Thuillier P, Bourhis D, Schick U, Alavi Z, Guezennec C, Robin P, Kerlan V, Salaun PY, Abgral R.

Q J Nucl Med Mol Imaging. 2019 Mar 25. doi: 10.23736/S1824-4785.19.03138-8. [Epub ahead of print]


Diagnostic Value of FDG PET-CT Quantitative Parameters and Deauville-Like 5 Point-Scale in Predicting Malignancy of Focal Thyroid Incidentaloma.

Thuillier P, Bourhis D, Roudaut N, Crouzeix G, Alavi Z, Schick U, Robin P, Kerlan V, Salaun PY, Abgral R.

Front Med (Lausanne). 2019 Feb 12;6:24. doi: 10.3389/fmed.2019.00024. eCollection 2019.


Dose to the penile bulb and individual patient anatomy are predictive of erectile dysfunction in men treated with 125I low dose rate brachytherapy for localized prostate cancer.

Chasseray M, Dissaux G, Bourbonne V, Boussion N, Goasduff G, Malloreau J, Malhaire JP, Fournier G, Tissot V, Pradier O, Valeri A, Schick U.

Acta Oncol. 2019 Jul;58(7):1029-1035. doi: 10.1080/0284186X.2019.1574981. Epub 2019 Feb 14.


Intensity-modulated radiotherapy for prostate cancer with seminal vesicle involvement (T3b): A multicentric retrospective analysis.

Goupy F, Supiot S, Pasquier D, Latorzeff I, Schick U, Monpetit E, Martinage G, Hervé C, Le Proust B, Castelli J, de Crevoisier R.

PLoS One. 2019 Jan 25;14(1):e0210514. doi: 10.1371/journal.pone.0210514. eCollection 2019.


Prognostic value of textural indices extracted from pretherapeutic 18-F FDG-PET/CT in head and neck squamous cell carcinoma.

Guezennec C, Robin P, Orlhac F, Bourhis D, Delcroix O, Gobel Y, Rousset J, Schick U, Salaün PY, Abgral R.

Head Neck. 2019 Feb;41(2):495-502. doi: 10.1002/hed.25433. Epub 2018 Dec 14.


External validation of a combined PET and MRI radiomics model for prediction of recurrence in cervical cancer patients treated with chemoradiotherapy.

Lucia F, Visvikis D, Vallières M, Desseroit MC, Miranda O, Robin P, Bonaffini PA, Alfieri J, Masson I, Mervoyer A, Reinhold C, Pradier O, Hatt M, Schick U.

Eur J Nucl Med Mol Imaging. 2019 Apr;46(4):864-877. doi: 10.1007/s00259-018-4231-9. Epub 2018 Dec 7.


A density assignment method for dose monitoring in head-and-neck radiotherapy.

Barateau A, Perichon N, Castelli J, Schick U, Henry O, Chajon E, Simon A, Lafond C, De Crevoisier R.

Strahlenther Onkol. 2019 Feb;195(2):175-185. doi: 10.1007/s00066-018-1379-y. Epub 2018 Oct 9.


[Image-guided radiotherapy for gynaecological cancer].

Lucia F, Schick U, Pradier O, Espenel S, de Crevoisier R, Chargari C.

Cancer Radiother. 2018 Oct;22(6-7):608-616. doi: 10.1016/j.canrad.2018.06.011. Epub 2018 Aug 17. Review. French.


Prostate Volume Segmentation in TRUS Using Hybrid Edge-Bhattacharyya Active Surfaces.

Jaouen V, Bert J, Mountris KA, Boussion N, Schick U, Pradier O, Valeri A, Visvikis D.

IEEE Trans Biomed Eng. 2019 Apr;66(4):920-933. doi: 10.1109/TBME.2018.2865428. Epub 2018 Aug 14.


Optimized radiotherapy to improve clinical outcomes for locally advanced lung cancer.

Jaksic N, Chajon E, Bellec J, Corre R, Ricordel C, de Latour B, Lena H, Schick U, de Crevoisier R, Castelli J.

Radiat Oncol. 2018 Aug 13;13(1):147. doi: 10.1186/s13014-018-1094-y.


Combined ATR and DNA-PK Inhibition Radiosensitizes Tumor Cells Independently of Their p53 Status.

Hafsi H, Dillon MT, Barker HE, Kyula JN, Schick U, Paget JT, Smith HG, Pedersen M, McLaughlin M, Harrington KJ.

Front Oncol. 2018 Jul 13;8:245. doi: 10.3389/fonc.2018.00245. eCollection 2018.


Inhomogeneous tumor dose distribution provides better local control than homogeneous distribution in stereotactic radiotherapy for brain metastases.

Lucia F, Key S, Dissaux G, Goasduff G, Lucia AS, Ollivier L, Pradier O, Schick U.

Radiother Oncol. 2019 Jan;130:132-138. doi: 10.1016/j.radonc.2018.06.039. Epub 2018 Jul 17.


FGFR1:TACC1 fusion is a frequent event in molecularly defined extraventricular neurocytoma.

Sievers P, Stichel D, Schrimpf D, Sahm F, Koelsche C, Reuss DE, Wefers AK, Reinhardt A, Huang K, Ebrahimi A, Hou Y, Pajtler KW, Pfister SM, Hasselblatt M, Stummer W, Schick U, Hartmann C, Hagel C, Staszewski O, Reifenberger G, Beschorner R, Coras R, Keyvani K, Kohlhof P, Diomedi-Camassei F, Herold-Mende C, Giangaspero F, Rushing E, Giannini C, Korshunov A, Jones DTW, von Deimling A.

Acta Neuropathol. 2018 Aug;136(2):293-302. doi: 10.1007/s00401-018-1882-3. Epub 2018 Jul 5.


Evaluation of the "Quadrella" at 3 years: New index to assess functional and oncological performance specific to prostate brachytherapy.

Coquet JB, Delage F, Fourcade A, Callerot P, Goasduff G, Boussion N, Rousseau B, Serey-Eiffel S, Malhaire JP, Pradier O, Schick U, Fournier G, Valeri A.

Brachytherapy. 2018 Sep - Oct;17(5):782-787. doi: 10.1016/j.brachy.2018.05.007. Epub 2018 Jun 21.


A Mismatch Repair-Deficient Hepatoid Adenocarcinoma of the Lung Responding to Anti-PD-L1 Durvalumab Therapy Despite no PD-L1 Expression.

Basse V, Schick U, Guéguen P, Le Maréchal C, Quintin-Roué I, Descourt R, Simon H, Uguen A, Quéré G.

J Thorac Oncol. 2018 Jul;13(7):e120-e122. doi: 10.1016/j.jtho.2018.03.004. No abstract available.


Generalization and fine mapping of red blood cell trait genetic associations to multi-ethnic populations: The PAGE Study.

Jo Hodonsky C, Schurmann C, Schick UM, Kocarnik J, Tao R, van Rooij FJ, Wassel C, Buyske S, Fornage M, Hindorff LA, Floyd JS, Ganesh SK, Lin DY, North KE, Reiner AP, Loos RJ, Kooperberg C, Avery CL.

Am J Hematol. 2018 Jun 15. doi: 10.1002/ajh.25161. [Epub ahead of print]


Diffuse Astrocytoma, IDH-Wildtype: A Dissolving Diagnosis.

Hasselblatt M, Jaber M, Reuss D, Grauer O, Bibo A, Terwey S, Schick U, Ebel H, Niederstadt T, Stummer W, von Deimling A, Paulus W.

J Neuropathol Exp Neurol. 2018 Jun 1;77(6):422-425. doi: 10.1093/jnen/nly012.


Incorporating spatial dose metrics in machine learning-based normal tissue complication probability (NTCP) models of severe acute dysphagia resulting from head and neck radiotherapy.

Dean J, Wong K, Gay H, Welsh L, Jones AB, Schick U, Oh JH, Apte A, Newbold K, Bhide S, Harrington K, Deasy J, Nutting C, Gulliford S.

Clin Transl Radiat Oncol. 2018 Jan;8:27-39. doi: 10.1016/j.ctro.2017.11.009. Epub 2017 Nov 21.


Prediction of outcome using pretreatment 18F-FDG PET/CT and MRI radiomics in locally advanced cervical cancer treated with chemoradiotherapy.

Lucia F, Visvikis D, Desseroit MC, Miranda O, Malhaire JP, Robin P, Pradier O, Hatt M, Schick U.

Eur J Nucl Med Mol Imaging. 2018 May;45(5):768-786. doi: 10.1007/s00259-017-3898-7. Epub 2017 Dec 9.


Mismatch repair-deficient colorectal cancer: a model of immunogenic and immune cell-rich tumor despite nonsignificant programmed cell death ligand-1 expression in tumor cells.

Le Flahec G, Badic B, Guibourg B, Doucet L, Bail JP, Marcorelles P, Schick U, Uguen A.

Hum Pathol. 2018 Feb;72:135-143. doi: 10.1016/j.humpath.2017.09.019. Epub 2017 Dec 5.


Target definition in salvage postoperative radiotherapy for prostate cancer: 18F-fluorocholine PET/CT assessment of local recurrence.

El Kabbaj O, Robin P, Bourhis D, Dissaux G, Rosenfelder N, Valeri A, Fournier G, Salaun PY, Pradier O, Malhaire JP, Abgral R, Schick U.

Acta Oncol. 2018 Mar;57(3):375-381. doi: 10.1080/0284186X.2017.1385843. Epub 2017 Oct 6.


CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits.

Macé A, Tuke MA, Deelen P, Kristiansson K, Mattsson H, Nõukas M, Sapkota Y, Schick U, Porcu E, Rüeger S, McDaid AF, Porteous D, Winkler TW, Salvi E, Shrine N, Liu X, Ang WQ, Zhang W, Feitosa MF, Venturini C, van der Most PJ, Rosengren A, Wood AR, Beaumont RN, Jones SE, Ruth KS, Yaghootkar H, Tyrrell J, Havulinna AS, Boers H, Mägi R, Kriebel J, Müller-Nurasyid M, Perola M, Nieminen M, Lokki ML, Kähönen M, Viikari JS, Geller F, Lahti J, Palotie A, Koponen P, Lundqvist A, Rissanen H, Bottinger EP, Afaq S, Wojczynski MK, Lenzini P, Nolte IM, Sparsø T, Schupf N, Christensen K, Perls TT, Newman AB, Werge T, Snieder H, Spector TD, Chambers JC, Koskinen S, Melbye M, Raitakari OT, Lehtimäki T, Tobin MD, Wain LV, Sinisalo J, Peters A, Meitinger T, Martin NG, Wray NR, Montgomery GW, Medland SE, Swertz MA, Vartiainen E, Borodulin K, Männistö S, Murray A, Bochud M, Jacquemont S, Rivadeneira F, Hansen TF, Oldehinkel AJ, Mangino M, Province MA, Deloukas P, Kooner JS, Freathy RM, Pennell C, Feenstra B, Strachan DP, Lettre G, Hirschhorn J, Cusi D, Heid IM, Hayward C, Männik K, Beckmann JS, Loos RJF, Nyholt DR, Metspalu A, Eriksson JG, Weedon MN, Salomaa V, Franke L, Reymond A, Frayling TM, Kutalik Z.

Nat Commun. 2017 Sep 29;8(1):744. doi: 10.1038/s41467-017-00556-x.


Clinical Validation of a Pixon-Based Reconstruction Method Allowing a Twofold Reduction in Planar Images Time of 111In-Pentetreotide Somatostatin Receptor Scintigraphy.

Thuillier P, Bourhis D, Robin P, Keromnes N, Schick U, Le Roux PY, Kerlan V, Chaumet-Riffaud P, Salaün PY, Abgral R.

Front Med (Lausanne). 2017 Aug 30;4:143. doi: 10.3389/fmed.2017.00143. eCollection 2017.


[Radiotherapy quality and risk manager role optimization in 2017].

Ponsard N, Brusadin G, Schick U.

Cancer Radiother. 2017 Oct;21(6-7):670-672. doi: 10.1016/j.canrad.2017.07.025. Epub 2017 Aug 30. French.


[Role of induction chemotherapy in head and neck cancer: Cons].

Huguet F, Schick U, Pointreau Y.

Cancer Radiother. 2017 Oct;21(6-7):510-514. doi: 10.1016/j.canrad.2017.07.020. French.


[Role and interest of induction chemotherapy for head and neck cancers].

Pointreau Y, Schick U, Huguet F.

Cancer Radiother. 2017 Oct;21(6-7):505-509. doi: 10.1016/j.canrad.2017.07.034. Epub 2017 Aug 31. French.


[Radiotherapy for head and neck squamous cell carcinoma: State of the art and future directions].

Schick U, Huguet F, Pointreau Y, Pradier O.

Cancer Radiother. 2017 Oct;21(6-7):498-504. doi: 10.1016/j.canrad.2017.07.032. Epub 2017 Aug 31. Review. French.


Cosmetic Outcome and Chronic Breast Toxicity After Intraoperative Radiation Therapy (IORT) as a Single Modality or as a Boost Using the Intrabeam® Device: A Prospective Study.

Key S, Miglierini P, Dupré PF, Guilbert S, Lucia AS, Abgral R, Conan-Charlet V, Uguen A, Pradier O, Schick U.

Ann Surg Oncol. 2017 Sep;24(9):2547-2555. doi: 10.1245/s10434-017-5920-5. Epub 2017 Jun 12.


Prolonged Overall Treatment Time and Lack of Skin Rash Negatively Impact Overall Survival in Locally Advanced Head and Neck Cancer Patients Treated with Radiotherapy and Concomitant Cetuximab.

Roman J, Dissaux G, Gouillou M, Gobel Y, Potard G, Leclere JC, Conan-Charlet V, Gujral D, Abgral R, Guibourg B, Pradier O, Schick U.

Target Oncol. 2017 Aug;12(4):505-512. doi: 10.1007/s11523-017-0499-0.


A Rare Case of ROS1 and ALK Double Rearranged Non-Small Cell Lung Cancer.

Uguen A, Schick U, Quéré G.

J Thorac Oncol. 2017 Jun;12(6):e71-e72. doi: 10.1016/j.jtho.2017.02.007. No abstract available.


[Radiotherapy volume delineation based on (18F)-fluorodeoxyglucose positron emission tomography for locally advanced or inoperable oesophageal cancer].

Encaoua J, Abgral R, Leleu C, El Kabbaj O, Caradec P, Bourhis D, Pradier O, Schick U.

Cancer Radiother. 2017 Jun;21(4):267-275. doi: 10.1016/j.canrad.2016.12.004. Epub 2017 May 9. French.


Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos.

Hodonsky CJ, Jain D, Schick UM, Morrison JV, Brown L, McHugh CP, Schurmann C, Chen DD, Liu YM, Auer PL, Laurie CA, Taylor KD, Browning BL, Li Y, Papanicolaou G, Rotter JI, Kurita R, Nakamura Y, Browning SR, Loos RJF, North KE, Laurie CC, Thornton TA, Pankratz N, Bauer DE, Sofer T, Reiner AP.

PLoS Genet. 2017 Apr 28;13(4):e1006760. doi: 10.1371/journal.pgen.1006760. eCollection 2017 Apr.


Correlation between fluorodeoxyglucose hotspots on pretreatment positron emission tomography/CT and preferential sites of local relapse after chemoradiotherapy for head and neck squamous cell carcinoma.

Chaput A, Calais J, Robin P, Thureau S, Bourhis D, Modzelewski R, Schick U, Vera P, Salaün PY, Abgral R.

Head Neck. 2017 Jun;39(6):1155-1165. doi: 10.1002/hed.24738. Epub 2017 Mar 6.


Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease.

Webb TR, Erdmann J, Stirrups KE, Stitziel NO, Masca NG, Jansen H, Kanoni S, Nelson CP, Ferrario PG, König IR, Eicher JD, Johnson AD, Hamby SE, Betsholtz C, Ruusalepp A, Franzén O, Schadt EE, Björkegren JL, Weeke PE, Auer PL, Schick UM, Lu Y, Zhang H, Dube MP, Goel A, Farrall M, Peloso GM, Won HH, Do R, van Iperen E, Kruppa J, Mahajan A, Scott RA, Willenborg C, Braund PS, van Capelleveen JC, Doney AS, Donnelly LA, Asselta R, Merlini PA, Duga S, Marziliano N, Denny JC, Shaffer C, El-Mokhtari NE, Franke A, Heilmann S, Hengstenberg C, Hoffmann P, Holmen OL, Hveem K, Jansson JH, Jöckel KH, Kessler T, Kriebel J, Laugwitz KL, Marouli E, Martinelli N, McCarthy MI, Van Zuydam NR, Meisinger C, Esko T, Mihailov E, Escher SA, Alver M, Moebus S, Morris AD, Virtamo J, Nikpay M, Olivieri O, Provost S, AlQarawi A, Robertson NR, Akinsansya KO, Reilly DF, Vogt TF, Yin W, Asselbergs FW, Kooperberg C, Jackson RD, Stahl E, Müller-Nurasyid M, Strauch K, Varga TV, Waldenberger M; Wellcome Trust Case Control Consortium, Zeng L, Chowdhury R, Salomaa V, Ford I, Jukema JW, Amouyel P, Kontto J; MORGAM Investigators, Nordestgaard BG, Ferrières J, Saleheen D, Sattar N, Surendran P, Wagner A, Young R, Howson JM, Butterworth AS, Danesh J, Ardissino D, Bottinger EP, Erbel R, Franks PW, Girelli D, Hall AS, Hovingh GK, Kastrati A, Lieb W, Meitinger T, Kraus WE, Shah SH, McPherson R, Orho-Melander M, Melander O, Metspalu A, Palmer CN, Peters A, Rader DJ, Reilly MP, Loos RJ, Reiner AP, Roden DM, Tardif JC, Thompson JR, Wareham NJ, Watkins H, Willer CJ, Samani NJ, Schunkert H, Deloukas P, Kathiresan S; Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators.

J Am Coll Cardiol. 2017 Feb 21;69(7):823-836. doi: 10.1016/j.jacc.2016.11.056.


Prospective analysis of neuropsychological deficits following resection of benign skull base meningiomas.

Zweckberger K, Hallek E, Vogt L, Giese H, Schick U, Unterberg AW.

J Neurosurg. 2017 Dec;127(6):1242-1248. doi: 10.3171/2016.10.JNS161936. Epub 2017 Feb 10.


Cerebral amyloidoma is characterized by B-cell clonality and a stable clinical course.

Heß K, Purrucker J, Hegenbart U, Brokinkel B, Berndt R, Keyvani K, Monoranu CM, Löhr M, Reifenberger G, Munoz-Bendix C, Kalla J, Groß J, Schick U, Kollmer J, Klapper W, Röcken C, Hasselblatt M, Paulus W.

Brain Pathol. 2018 Mar;28(2):234-239. doi: 10.1111/bpa.12493. Epub 2017 Mar 13.


Genome-wide association of white blood cell counts in Hispanic/Latino Americans: the Hispanic Community Health Study/Study of Latinos.

Jain D, Hodonsky CJ, Schick UM, Morrison JV, Minnerath S, Brown L, Schurmann C, Liu Y, Auer PL, Laurie CA, Taylor KD, Browning BL, Papanicolaou G, Browning SR, Loos RJF, North KE, Thyagarajan B, Laurie CC, Thornton TA, Sofer T, Reiner AP.

Hum Mol Genet. 2017 Mar 15;26(6):1193-1204. doi: 10.1093/hmg/ddx024.

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