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Items: 1 to 50 of 134


Force-induced conformational changes in PIEZO1.

Lin YC, Guo YR, Miyagi A, Levring J, MacKinnon R, Scheuring S.

Nature. 2019 Sep;573(7773):230-234. doi: 10.1038/s41586-019-1499-2. Epub 2019 Aug 21.


Professionals' Perceptions: "Why is Lead Poisoning Prevalent in Lancaster County?"

Okatch H, Cherney M, Mokshefsky B, Kuon M, Scheuring S, Ritchey E, Chen J.

Int J Environ Res Public Health. 2019 Jun 27;16(13). pii: E2281. doi: 10.3390/ijerph16132281.


Heterogeneous and rate-dependent streptavidin-biotin unbinding revealed by high-speed force spectroscopy and atomistic simulations.

Rico F, Russek A, González L, Grubmüller H, Scheuring S.

Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6594-6601. doi: 10.1073/pnas.1816909116. Epub 2019 Mar 19.


Advances in high-speed atomic force microscopy (HS-AFM) reveal dynamics of transmembrane channels and transporters.

Heath GR, Scheuring S.

Curr Opin Struct Biol. 2019 Aug;57:93-102. doi: 10.1016/ Epub 2019 Mar 14. Review.


Fifteen years of Servitude et Grandeur to the application of a biophysical technique in medicine: The tale of AFMBioMed.

Pellequer JL, Parot P, Navajas D, Kumar S, Svetličić V, Scheuring S, Hu J, Li B, Engler A, Sousa S, Lekka M, Szymoński M, Schillers H, Odorico M, Lafont F, Janel S, Rico F.

J Mol Recognit. 2019 Mar;32(3):e2773. doi: 10.1002/jmr.2773. Epub 2018 Dec 18.


High-speed AFM height spectroscopy reveals µs-dynamics of unlabeled biomolecules.

Heath GR, Scheuring S.

Nat Commun. 2018 Nov 26;9(1):4983. doi: 10.1038/s41467-018-07512-3.


An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel.

Marchesi A, Gao X, Adaixo R, Rheinberger J, Stahlberg H, Nimigean C, Scheuring S.

Nat Commun. 2018 Sep 28;9(1):3978. doi: 10.1038/s41467-018-06414-8.


A novel phase-shift-based amplitude detector for a high-speed atomic force microscope.

Miyagi A, Scheuring S.

Rev Sci Instrum. 2018 Aug;89(8):083704. doi: 10.1063/1.5038095.


Structural titration of receptor ion channel GLIC gating by HS-AFM.

Ruan Y, Kao K, Lefebvre S, Marchesi A, Corringer PJ, Hite RK, Scheuring S.

Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10333-10338. doi: 10.1073/pnas.1805621115. Epub 2018 Sep 4.


High-Speed Force Spectroscopy for Single Protein Unfolding.

Sumbul F, Marchesi A, Takahashi H, Scheuring S, Rico F.

Methods Mol Biol. 2018;1814:243-264. doi: 10.1007/978-1-4939-8591-3_15.


α-Helix Unwinding as Force Buffer in Spectrins.

Takahashi H, Rico F, Chipot C, Scheuring S.

ACS Nano. 2018 Mar 27;12(3):2719-2727. doi: 10.1021/acsnano.7b08973. Epub 2018 Feb 6.


High-Speed Atomic Force Microscopy Reveals the Inner Workings of the MinDE Protein Oscillator.

Miyagi A, Ramm B, Schwille P, Scheuring S.

Nano Lett. 2018 Jan 10;18(1):288-296. doi: 10.1021/acs.nanolett.7b04128. Epub 2017 Dec 18.


Lysenin Toxin Membrane Insertion Is pH-Dependent but Independent of Neighboring Lysenins.

Munguira ILB, Takahashi H, Casuso I, Scheuring S.

Biophys J. 2017 Nov 7;113(9):2029-2036. doi: 10.1016/j.bpj.2017.08.056.


High-frequency microrheology reveals cytoskeleton dynamics in living cells.

Rigato A, Miyagi A, Scheuring S, Rico F.

Nat Phys. 2017 Aug;13(8):771-775. doi: 10.1038/nphys4104. Epub 2017 May 1.


Applications of high-speed atomic force microscopy to real-time visualization of dynamic biomolecular processes.

Uchihashi T, Scheuring S.

Biochim Biophys Acta Gen Subj. 2018 Feb;1862(2):229-240. doi: 10.1016/j.bbagen.2017.07.010. Epub 2017 Jul 15. Review.


Standardized Nanomechanical Atomic Force Microscopy Procedure (SNAP) for Measuring Soft and Biological Samples.

Schillers H, Rianna C, Schäpe J, Luque T, Doschke H, Wälte M, Uriarte JJ, Campillo N, Michanetzis GPA, Bobrowska J, Dumitru A, Herruzo ET, Bovio S, Parot P, Galluzzi M, Podestà A, Puricelli L, Scheuring S, Missirlis Y, Garcia R, Odorico M, Teulon JM, Lafont F, Lekka M, Rico F, Rigato A, Pellequer JL, Oberleithner H, Navajas D, Radmacher M.

Sci Rep. 2017 Jul 11;7(1):5117. doi: 10.1038/s41598-017-05383-0.


Dynamic subunit turnover in ESCRT-III assemblies is regulated by Vps4 to mediate membrane remodelling during cytokinesis.

Mierzwa BE, Chiaruttini N, Redondo-Morata L, von Filseck JM, König J, Larios J, Poser I, Müller-Reichert T, Scheuring S, Roux A, Gerlich DW.

Nat Cell Biol. 2017 Jul;19(7):787-798. doi: 10.1038/ncb3559. Epub 2017 Jun 12.


Dynamic remodeling of the dynamin helix during membrane constriction.

Colom A, Redondo-Morata L, Chiaruttini N, Roux A, Scheuring S.

Proc Natl Acad Sci U S A. 2017 May 23;114(21):5449-5454. doi: 10.1073/pnas.1619578114. Epub 2017 May 8.


Real-time Visualization of Phospholipid Degradation by Outer Membrane Phospholipase A using High-Speed Atomic Force Microscopy.

Rangl M, Rima L, Klement J, Miyagi A, Keller S, Scheuring S.

J Mol Biol. 2017 Apr 7;429(7):977-986. doi: 10.1016/j.jmb.2017.03.004. Epub 2017 Mar 7.


Engineering a pH responsive pore forming protein.

Kisovec M, Rezelj S, Knap P, Cajnko MM, Caserman S, Flašker A, Žnidaršič N, Repič M, Mavri J, Ruan Y, Scheuring S, Podobnik M, Anderluh G.

Sci Rep. 2017 Feb 8;7:42231. doi: 10.1038/srep42231.


Direct visualization of glutamate transporter elevator mechanism by high-speed AFM.

Ruan Y, Miyagi A, Wang X, Chami M, Boudker O, Scheuring S.

Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1584-1588. doi: 10.1073/pnas.1616413114. Epub 2017 Jan 30.


Temperature-Controlled High-Speed AFM: Real-Time Observation of Ripple Phase Transitions.

Takahashi H, Miyagi A, Redondo-Morata L, Scheuring S.

Small. 2016 Nov;12(44):6106-6113. doi: 10.1002/smll.201601549. Epub 2016 Sep 20.


Real-time visualization of conformational changes within single MloK1 cyclic nucleotide-modulated channels.

Rangl M, Miyagi A, Kowal J, Stahlberg H, Nimigean CM, Scheuring S.

Nat Commun. 2016 Sep 20;7:12789. doi: 10.1038/ncomms12789.


Effect of Statins on the Nanomechanical Properties of Supported Lipid Bilayers.

Redondo-Morata L, Lea Sanford R, Andersen OS, Scheuring S.

Biophys J. 2016 Jul 26;111(2):363-372. doi: 10.1016/j.bpj.2016.06.016.


Identification of a Membrane-bound Prepore Species Clarifies the Lytic Mechanism of Actinoporins.

Morante K, Bellomio A, Gil-Cartón D, Redondo-Morata L, Sot J, Scheuring S, Valle M, González-Mañas JM, Tsumoto K, Caaveiro JMM.

J Biol Chem. 2016 Sep 9;291(37):19210-19219. doi: 10.1074/jbc.M116.734053. Epub 2016 Jul 21.


High-speed atomic force microscopy shows that annexin V stabilizes membranes on the second timescale.

Miyagi A, Chipot C, Rangl M, Scheuring S.

Nat Nanotechnol. 2016 Sep;11(9):783-90. doi: 10.1038/nnano.2016.89. Epub 2016 Jun 6.


Automated force controller for amplitude modulation atomic force microscopy.

Miyagi A, Scheuring S.

Rev Sci Instrum. 2016 May;87(5):053705. doi: 10.1063/1.4950777.


Listeriolysin O Membrane Damaging Activity Involves Arc Formation and Lineaction -- Implication for Listeria monocytogenes Escape from Phagocytic Vacuole.

Ruan Y, Rezelj S, Bedina Zavec A, Anderluh G, Scheuring S.

PLoS Pathog. 2016 Apr 22;12(4):e1005597. doi: 10.1371/journal.ppat.1005597. eCollection 2016 Apr.


Temperature-Switchable Control of Ligand Display on Adlayers of Mixed Poly(lysine)-g-(PEO) and Poly(lysine)-g-(ligand-modified poly-N-isopropylacrylamide).

Dalier F, Eghiaian F, Scheuring S, Marie E, Tribet C.

Biomacromolecules. 2016 May 9;17(5):1727-36. doi: 10.1021/acs.biomac.6b00136. Epub 2016 Apr 12.


Glasslike Membrane Protein Diffusion in a Crowded Membrane.

Munguira I, Casuso I, Takahashi H, Rico F, Miyagi A, Chami M, Scheuring S.

ACS Nano. 2016 Feb 23;10(2):2584-90. doi: 10.1021/acsnano.5b07595. Epub 2016 Feb 11.


Corrigendum to "High-speed atomic force microscopy: Imaging and force spectroscopy" [FEBS Lett. 588 (19) (2014) 3631-3638].

Eghiaian F, Rico F, Colom A, Casuso I, Scheuring S.

FEBS Lett. 2015 May 22;589(12):1389. doi: 10.1016/j.febslet.2015.04.027. No abstract available.


Relaxation of Loaded ESCRT-III Spiral Springs Drives Membrane Deformation.

Chiaruttini N, Redondo-Morata L, Colom A, Humbert F, Lenz M, Scheuring S, Roux A.

Cell. 2015 Nov 5;163(4):866-79. doi: 10.1016/j.cell.2015.10.017. Epub 2015 Oct 29.


Atomic Force Microscopy Mechanical Mapping of Micropatterned Cells Shows Adhesion Geometry-Dependent Mechanical Response on Local and Global Scales.

Rigato A, Rico F, Eghiaian F, Piel M, Scheuring S.

ACS Nano. 2015 Jun 23;9(6):5846-56. doi: 10.1021/acsnano.5b00430. Epub 2015 Jun 2.


Structural, mechanical, and dynamical variability of the actin cortex in living cells.

Eghiaian F, Rigato A, Scheuring S.

Biophys J. 2015 Mar 24;108(6):1330-1340. doi: 10.1016/j.bpj.2015.01.016.


Cannabinoid-induced actomyosin contractility shapes neuronal morphology and growth.

Roland AB, Ricobaraza A, Carrel D, Jordan BM, Rico F, Simon A, Humbert-Claude M, Ferrier J, McFadden MH, Scheuring S, Lenkei Z.

Elife. 2014 Sep 15;3:e03159. doi: 10.7554/eLife.03159.


High-speed atomic force microscopy: imaging and force spectroscopy.

Eghiaian F, Rico F, Colom A, Casuso I, Scheuring S.

FEBS Lett. 2014 Oct 1;588(19):3631-8. doi: 10.1016/j.febslet.2014.06.028. Epub 2014 Jun 14. Review. Erratum in: FEBS Lett. 2015 May 22;589(12):1389.


Light harvesting by lamellar chromatophores in Rhodospirillum photometricum.

Chandler DE, Strümpfer J, Sener M, Scheuring S, Schulten K.

Biophys J. 2014 Jun 3;106(11):2503-10. doi: 10.1016/j.bpj.2014.04.030.


The architecture of Rhodobacter sphaeroides chromatophores.

Scheuring S, Nevo R, Liu LN, Mangenot S, Charuvi D, Boudier T, Prima V, Hubert P, Sturgis JN, Reich Z.

Biochim Biophys Acta. 2014 Aug;1837(8):1263-70. doi: 10.1016/j.bbabio.2014.03.011. Epub 2014 Mar 28.


Mechanics of proteins with a focus on atomic force microscopy.

Rico F, Rigato A, Picas L, Scheuring S.

J Nanobiotechnology. 2013;11 Suppl 1:S3. doi: 10.1186/1477-3155-11-S1-S3. Epub 2013 Dec 10.


Filming biomolecular processes by high-speed atomic force microscopy.

Ando T, Uchihashi T, Scheuring S.

Chem Rev. 2014 Mar 26;114(6):3120-88. doi: 10.1021/cr4003837. Epub 2014 Jan 30. Review. No abstract available.


Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1.

Kowal J, Chami M, Baumgartner P, Arheit M, Chiu PL, Rangl M, Scheuring S, Schröder GF, Nimigean CM, Stahlberg H.

Nat Commun. 2014;5:3106. doi: 10.1038/ncomms4106.


High-speed force spectroscopy unfolds titin at the velocity of molecular dynamics simulations.

Rico F, Gonzalez L, Casuso I, Puig-Vidal M, Scheuring S.

Science. 2013 Nov 8;342(6159):741-3. doi: 10.1126/science.1239764.


High-speed atomic force microscopy tracks toxin action.

Scheuring S.

Biophys J. 2013 Sep 17;105(6):1292. doi: 10.1016/j.bpj.2013.08.004. No abstract available.


Cellular capsules as a tool for multicellular spheroid production and for investigating the mechanics of tumor progression in vitro.

Alessandri K, Sarangi BR, Gurchenkov VV, Sinha B, Kießling TR, Fetler L, Rico F, Scheuring S, Lamaze C, Simon A, Geraldo S, Vignjevic D, Doméjean H, Rolland L, Funfak A, Bibette J, Bremond N, Nassoy P.

Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):14843-8. doi: 10.1073/pnas.1309482110. Epub 2013 Aug 26.


A hybrid high-speed atomic force-optical microscope for visualizing single membrane proteins on eukaryotic cells.

Colom A, Casuso I, Rico F, Scheuring S.

Nat Commun. 2013;4:2155. doi: 10.1038/ncomms3155.


Investigation of photosynthetic membrane structure using atomic force microscopy.

Liu LN, Scheuring S.

Trends Plant Sci. 2013 May;18(5):277-86. doi: 10.1016/j.tplants.2013.03.001. Epub 2013 Apr 2. Review.


Structural and mechanical heterogeneity of the erythrocyte membrane reveals hallmarks of membrane stability.

Picas L, Rico F, Deforet M, Scheuring S.

ACS Nano. 2013 Feb 26;7(2):1054-63. doi: 10.1021/nn303824j. Epub 2013 Jan 30.


High-speed atomic force microscopy: cooperative adhesion and dynamic equilibrium of junctional microdomain membrane proteins.

Colom A, Casuso I, Boudier T, Scheuring S.

J Mol Biol. 2012 Oct 19;423(2):249-56. doi: 10.1016/j.jmb.2012.07.004. Epub 2012 Jul 14.


Characterization of the motion of membrane proteins using high-speed atomic force microscopy.

Casuso I, Khao J, Chami M, Paul-Gilloteaux P, Husain M, Duneau JP, Stahlberg H, Sturgis JN, Scheuring S.

Nat Nanotechnol. 2012 Aug;7(8):525-9. doi: 10.1038/nnano.2012.109. Epub 2012 Jul 8.


Software for drift compensation, particle tracking and particle analysis of high-speed atomic force microscopy image series.

Husain M, Boudier T, Paul-Gilloteaux P, Casuso I, Scheuring S.

J Mol Recognit. 2012 May;25(5):292-8. doi: 10.1002/jmr.2187.


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