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Items: 1 to 50 of 189

1.

Transient improvement of cerebellar oligodendroglial development in a neonatal hyperoxia model by PDGFA treatment.

Scheuer T, Klein LS, Bührer C, Endesfelder S, Schmitz T.

Dev Neurobiol. 2019 Jan 23. doi: 10.1002/dneu.22667. [Epub ahead of print]

PMID:
30674088
2.

Neonatal Hyperoxia Perturbs Neuronal Development in the Cerebellum.

Scheuer T, Sharkovska Y, Tarabykin V, Marggraf K, Brockmöller V, Bührer C, Endesfelder S, Schmitz T.

Mol Neurobiol. 2018 May;55(5):3901-3915. doi: 10.1007/s12035-017-0612-5. Epub 2017 May 25.

PMID:
28547531
3.

Corrigendum: Oxygen impairs oligodendroglial development via oxidative stress and reduced expression of HIF-1α.

Brill C, Scheuer T, Bührer C, Endesfelder S, Schmitz T.

Sci Rep. 2017 May 12;7:46800. doi: 10.1038/srep46800. No abstract available.

4.

Oxygen impairs oligodendroglial development via oxidative stress and reduced expression of HIF-1α.

Brill C, Scheuer T, Bührer C, Endesfelder S, Schmitz T.

Sci Rep. 2017 Feb 23;7:43000. doi: 10.1038/srep43000. Erratum in: Sci Rep. 2017 May 12;7:46800.

5.

Neuroprotection by Caffeine in Hyperoxia-Induced Neonatal Brain Injury.

Endesfelder S, Weichelt U, Strauß E, Schlör A, Sifringer M, Scheuer T, Bührer C, Schmitz T.

Int J Mol Sci. 2017 Jan 18;18(1). pii: E187. doi: 10.3390/ijms18010187.

6.

Association of rare missense variants in the second intracellular loop of NaV1.7 sodium channels with familial autism.

Rubinstein M, Patowary A, Stanaway IB, McCord E, Nesbitt RR, Archer M, Scheuer T, Nickerson D, Raskind WH, Wijsman EM, Bernier R, Catterall WA, Brkanac Z.

Mol Psychiatry. 2018 Feb;23(2):231-239. doi: 10.1038/mp.2016.222. Epub 2016 Dec 13.

7.

Calcium sensor regulation of the CaV2.1 Ca2+ channel contributes to long-term potentiation and spatial learning.

Nanou E, Scheuer T, Catterall WA.

Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):13209-13214. Epub 2016 Oct 31.

8.

Structural basis for inhibition of a voltage-gated Ca2+ channel by Ca2+ antagonist drugs.

Tang L, Gamal El-Din TM, Swanson TM, Pryde DC, Scheuer T, Zheng N, Catterall WA.

Nature. 2016 Sep 1;537(7618):117-121. doi: 10.1038/nature19102. Epub 2016 Aug 24.

9.

Calcium sensor regulation of the CaV2.1 Ca2+ channel contributes to short-term synaptic plasticity in hippocampal neurons.

Nanou E, Sullivan JM, Scheuer T, Catterall WA.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):1062-7. doi: 10.1073/pnas.1524636113. Epub 2016 Jan 11.

10.

Altered short-term synaptic plasticity and reduced muscle strength in mice with impaired regulation of presynaptic CaV2.1 Ca2+ channels.

Nanou E, Yan J, Whitehead NP, Kim MJ, Froehner SC, Scheuer T, Catterall WA.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):1068-73. doi: 10.1073/pnas.1524650113. Epub 2016 Jan 11.

11.

Phosphorylation sites in the Hook domain of CaVβ subunits differentially modulate CaV1.2 channel function.

Brunet S, Emrick MA, Sadilek M, Scheuer T, Catterall WA.

J Mol Cell Cardiol. 2015 Oct;87:248-56. doi: 10.1016/j.yjmcc.2015.08.006. Epub 2015 Aug 10.

12.

Dissecting the phenotypes of Dravet syndrome by gene deletion.

Rubinstein M, Han S, Tai C, Westenbroek RE, Hunker A, Scheuer T, Catterall WA.

Brain. 2015 Aug;138(Pt 8):2219-33. doi: 10.1093/brain/awv142. Epub 2015 May 27.

13.

Oligodendroglial maldevelopment in the cerebellum after postnatal hyperoxia and its prevention by minocycline.

Scheuer T, Brockmöller V, Blanco Knowlton M, Weitkamp JH, Ruhwedel T, Mueller S, Endesfelder S, Bührer C, Schmitz T.

Glia. 2015 Oct;63(10):1825-39. doi: 10.1002/glia.22847. Epub 2015 May 12.

14.

Sleep impairment and reduced interneuron excitability in a mouse model of Dravet Syndrome.

Kalume F, Oakley JC, Westenbroek RE, Gile J, de la Iglesia HO, Scheuer T, Catterall WA.

Neurobiol Dis. 2015 May;77:141-54. doi: 10.1016/j.nbd.2015.02.016. Epub 2015 Mar 10.

15.

Modulation of CaV2.1 channels by neuronal calcium sensor-1 induces short-term synaptic facilitation.

Yan J, Leal K, Magupalli VG, Nanou E, Martinez GQ, Scheuer T, Catterall WA.

Mol Cell Neurosci. 2014 Nov;63:124-31.

16.

Basal and β-adrenergic regulation of the cardiac calcium channel CaV1.2 requires phosphorylation of serine 1700.

Fu Y, Westenbroek RE, Scheuer T, Catterall WA.

Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16598-603. doi: 10.1073/pnas.1419129111. Epub 2014 Nov 3.

17.

Genetic background modulates impaired excitability of inhibitory neurons in a mouse model of Dravet syndrome.

Rubinstein M, Westenbroek RE, Yu FH, Jones CJ, Scheuer T, Catterall WA.

Neurobiol Dis. 2015 Jan;73:106-17. doi: 10.1016/j.nbd.2014.09.017. Epub 2014 Oct 2.

18.

Tracking S4 movement by gating pore currents in the bacterial sodium channel NaChBac.

Gamal El-Din TM, Scheuer T, Catterall WA.

J Gen Physiol. 2014 Aug;144(2):147-57. doi: 10.1085/jgp.201411210.

19.

Impaired excitability of somatostatin- and parvalbumin-expressing cortical interneurons in a mouse model of Dravet syndrome.

Tai C, Abe Y, Westenbroek RE, Scheuer T, Catterall WA.

Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):E3139-48. doi: 10.1073/pnas.1411131111. Epub 2014 Jul 14.

20.

Reciprocal changes in phosphorylation and methylation of mammalian brain sodium channels in response to seizures.

Baek JH, Rubinstein M, Scheuer T, Trimmer JS.

J Biol Chem. 2014 May 30;289(22):15363-73. doi: 10.1074/jbc.M114.562785. Epub 2014 Apr 15.

21.

Bacterial sodium channels: models for eukaryotic sodium and calcium channels.

Scheuer T.

Handb Exp Pharmacol. 2014;221:269-91. doi: 10.1007/978-3-642-41588-3_13. Review.

PMID:
24737241
22.

Enhancement of inhibitory neurotransmission by GABAA receptors having α2,3-subunits ameliorates behavioral deficits in a mouse model of autism.

Han S, Tai C, Jones CJ, Scheuer T, Catterall WA.

Neuron. 2014 Mar 19;81(6):1282-1289. doi: 10.1016/j.neuron.2014.01.016.

23.

Differential regulation of CaV1.2 channels by cAMP-dependent protein kinase bound to A-kinase anchoring proteins 15 and 79/150.

Fuller MD, Fu Y, Scheuer T, Catterall WA.

J Gen Physiol. 2014 Mar;143(3):315-24. doi: 10.1085/jgp.201311075.

24.

Minocycline protects the immature white matter against hyperoxia.

Schmitz T, Krabbe G, Weikert G, Scheuer T, Matheus F, Wang Y, Mueller S, Kettenmann H, Matyash V, Bührer C, Endesfelder S.

Exp Neurol. 2014 Apr;254:153-65. doi: 10.1016/j.expneurol.2014.01.017. Epub 2014 Jan 31.

PMID:
24491957
25.

Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.

Tang L, Gamal El-Din TM, Payandeh J, Martinez GQ, Heard TM, Scheuer T, Zheng N, Catterall WA.

Nature. 2014 Jan 2;505(7481):56-61. doi: 10.1038/nature12775. Epub 2013 Nov 24.

26.

Phosphorylation sites required for regulation of cardiac calcium channels in the fight-or-flight response.

Fu Y, Westenbroek RE, Scheuer T, Catterall WA.

Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19621-6. doi: 10.1073/pnas.1319421110. Epub 2013 Nov 11. Erratum in: Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):3895.

27.

Distinct global shifts in genomic binding profiles of limb malformation-associated HOXD13 mutations.

Ibrahim DM, Hansen P, Rödelsperger C, Stiege AC, Doelken SC, Horn D, Jäger M, Janetzki C, Krawitz P, Leschik G, Wagner F, Scheuer T, Schmidt-von Kegler M, Seemann P, Timmermann B, Robinson PN, Mundlos S, Hecht J.

Genome Res. 2013 Dec;23(12):2091-102. doi: 10.1101/gr.157610.113. Epub 2013 Aug 30.

28.

Localization of sodium channel subtypes in mouse ventricular myocytes using quantitative immunocytochemistry.

Westenbroek RE, Bischoff S, Fu Y, Maier SK, Catterall WA, Scheuer T.

J Mol Cell Cardiol. 2013 Nov;64:69-78. doi: 10.1016/j.yjmcc.2013.08.004. Epub 2013 Aug 24.

29.

A gating charge interaction required for late slow inactivation of the bacterial sodium channel NavAb.

Gamal El-Din TM, Martinez GQ, Payandeh J, Scheuer T, Catterall WA.

J Gen Physiol. 2013 Sep;142(3):181-90. doi: 10.1085/jgp.201311012.

30.

Distribution and function of sodium channel subtypes in human atrial myocardium.

Kaufmann SG, Westenbroek RE, Maass AH, Lange V, Renner A, Wischmeyer E, Bonz A, Muck J, Ertl G, Catterall WA, Scheuer T, Maier SKG.

J Mol Cell Cardiol. 2013 Aug;61:133-141. doi: 10.1016/j.yjmcc.2013.05.006. Epub 2013 May 20.

31.

Sudden unexpected death in a mouse model of Dravet syndrome.

Kalume F, Westenbroek RE, Cheah CS, Yu FH, Oakley JC, Scheuer T, Catterall WA.

J Clin Invest. 2013 Apr;123(4):1798-808. doi: 10.1172/JCI66220. Epub 2013 Mar 25.

32.

Synergistic GABA-enhancing therapy against seizures in a mouse model of Dravet syndrome.

Oakley JC, Cho AR, Cheah CS, Scheuer T, Catterall WA.

J Pharmacol Exp Ther. 2013 May;345(2):215-24. doi: 10.1124/jpet.113.203331. Epub 2013 Feb 19.

33.

Ca2+-independent activation of Ca2+/calmodulin-dependent protein kinase II bound to the C-terminal domain of CaV2.1 calcium channels.

Magupalli VG, Mochida S, Yan J, Jiang X, Westenbroek RE, Nairn AC, Scheuer T, Catterall WA.

J Biol Chem. 2013 Feb 15;288(7):4637-48. doi: 10.1074/jbc.M112.369058. Epub 2012 Dec 19.

34.

Increased intracellular magnesium attenuates β-adrenergic stimulation of the cardiac Ca(V)1.2 channel.

Brunet S, Scheuer T, Catterall WA.

J Gen Physiol. 2013 Jan;141(1):85-94. doi: 10.1085/jgp.201210864. Epub 2012 Dec 17.

35.

Fine-tuning synaptic plasticity by modulation of Ca(V)2.1 channels with Ca2+ sensor proteins.

Leal K, Mochida S, Scheuer T, Catterall WA.

Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):17069-74. doi: 10.1073/pnas.1215172109. Epub 2012 Oct 1.

36.

Autistic-like behaviour in Scn1a+/- mice and rescue by enhanced GABA-mediated neurotransmission.

Han S, Tai C, Westenbroek RE, Yu FH, Cheah CS, Potter GB, Rubenstein JL, Scheuer T, de la Iglesia HO, Catterall WA.

Nature. 2012 Sep 20;489(7416):385-90. doi: 10.1038/nature11356. Epub 2012 Aug 22.

37.

Mapping the interaction site for a β-scorpion toxin in the pore module of domain III of voltage-gated Na(+) channels.

Zhang JZ, Yarov-Yarovoy V, Scheuer T, Karbat I, Cohen L, Gordon D, Gurevitz M, Catterall WA.

J Biol Chem. 2012 Aug 31;287(36):30719-28. doi: 10.1074/jbc.M112.370742. Epub 2012 Jul 2.

38.

Crystal structure of a voltage-gated sodium channel in two potentially inactivated states.

Payandeh J, Gamal El-Din TM, Scheuer T, Zheng N, Catterall WA.

Nature. 2012 May 20;486(7401):135-9. doi: 10.1038/nature11077.

39.

Asynchronous Ca2+ current conducted by voltage-gated Ca2+ (CaV)-2.1 and CaV2.2 channels and its implications for asynchronous neurotransmitter release.

Few AP, Nanou E, Watari H, Sullivan JM, Scheuer T, Catterall WA.

Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):E452-60. doi: 10.1073/pnas.1121103109. Epub 2012 Jan 23.

40.

Structural basis for gating charge movement in the voltage sensor of a sodium channel.

Yarov-Yarovoy V, DeCaen PG, Westenbroek RE, Pan CY, Scheuer T, Baker D, Catterall WA.

Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):E93-102. doi: 10.1073/pnas.1118434109. Epub 2011 Dec 12.

41.

Molecular determinants of modulation of CaV2.1 channels by visinin-like protein 2.

Nanou E, Martinez GQ, Scheuer T, Catterall WA.

J Biol Chem. 2012 Jan 2;287(1):504-13. doi: 10.1074/jbc.M111.292581. Epub 2011 Nov 10.

42.

Gating charge interactions with the S1 segment during activation of a Na+ channel voltage sensor.

DeCaen PG, Yarov-Yarovoy V, Scheuer T, Catterall WA.

Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18825-30. doi: 10.1073/pnas.1116449108. Epub 2011 Oct 31.

43.

Molecular determinants of CaV2.1 channel regulation by calcium-binding protein-1.

Few AP, Nanou E, Scheuer T, Catterall WA.

J Biol Chem. 2011 Dec 9;286(49):41917-23. doi: 10.1074/jbc.M111.292417. Epub 2011 Sep 29.

44.

Mapping the receptor site for alpha-scorpion toxins on a Na+ channel voltage sensor.

Wang J, Yarov-Yarovoy V, Kahn R, Gordon D, Gurevitz M, Scheuer T, Catterall WA.

Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15426-31. doi: 10.1073/pnas.1112320108. Epub 2011 Aug 29. Erratum in: Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3645.

45.

Structure-function map of the receptor site for β-scorpion toxins in domain II of voltage-gated sodium channels.

Zhang JZ, Yarov-Yarovoy V, Scheuer T, Karbat I, Cohen L, Gordon D, Gurevitz M, Catterall WA.

J Biol Chem. 2011 Sep 23;286(38):33641-51. doi: 10.1074/jbc.M111.282509. Epub 2011 Jul 27.

46.

The crystal structure of a voltage-gated sodium channel.

Payandeh J, Scheuer T, Zheng N, Catterall WA.

Nature. 2011 Jul 10;475(7356):353-8. doi: 10.1038/nature10238.

47.

Functional roles of a C-terminal signaling complex of CaV1 channels and A-kinase anchoring protein 15 in brain neurons.

Marshall MR, Clark JP 3rd, Westenbroek R, Yu FH, Scheuer T, Catterall WA.

J Biol Chem. 2011 Apr 8;286(14):12627-39. doi: 10.1074/jbc.M110.175257. Epub 2011 Jan 11.

48.

Deletion of the distal C terminus of CaV1.2 channels leads to loss of beta-adrenergic regulation and heart failure in vivo.

Fu Y, Westenbroek RE, Yu FH, Clark JP 3rd, Marshall MR, Scheuer T, Catterall WA.

J Biol Chem. 2011 Apr 8;286(14):12617-26. doi: 10.1074/jbc.M110.175307. Epub 2011 Jan 7.

49.

Regulation of sodium channel activity by phosphorylation.

Scheuer T.

Semin Cell Dev Biol. 2011 Apr;22(2):160-5. doi: 10.1016/j.semcdb.2010.10.002. Epub 2010 Oct 13. Review.

50.

Molecular mechanism of calcium channel regulation in the fight-or-flight response.

Fuller MD, Emrick MA, Sadilek M, Scheuer T, Catterall WA.

Sci Signal. 2010 Sep 28;3(141):ra70. doi: 10.1126/scisignal.2001152.

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