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Items: 1 to 50 of 392

1.

Adiponectin modulates ventral tegmental area dopamine neuron activity and anxiety-related behavior through AdipoR1.

Sun F, Lei Y, You J, Li C, Sun L, Garza J, Zhang D, Guo M, Scherer PE, Lodge D, Lu XY.

Mol Psychiatry. 2018 Jul 9. doi: 10.1038/s41380-018-0102-9. [Epub ahead of print]

PMID:
29988086
2.

Skin aging as a mechanical phenomenon: The main weak links.

Kruglikov IL, Scherer PE.

Nutr Healthy Aging. 2018 Jun 15;4(4):291-307. doi: 10.3233/NHA-170037.

3.

Loss of Tbk1 kinase activity protects mice from diet-induced metabolic dysfunction.

Cruz VH, Arner EN, Wynne KW, Scherer PE, Brekken RA.

Mol Metab. 2018 Jun 11. pii: S2212-8778(18)30420-4. doi: 10.1016/j.molmet.2018.06.007. [Epub ahead of print]

4.

Reversible De-differentiation of Mature White Adipocytes into Preadipocyte-like Precursors during Lactation.

Wang QA, Song A, Chen W, Schwalie PC, Zhang F, Vishvanath L, Jiang L, Ye R, Shao M, Tao C, Gupta RK, Deplancke B, Scherer PE.

Cell Metab. 2018 Jun 8. pii: S1550-4131(18)30329-2. doi: 10.1016/j.cmet.2018.05.022. [Epub ahead of print]

PMID:
29909970
5.

Hepatocyte toll-like receptor 4 deficiency protects against alcohol-induced fatty liver disease.

Jia L, Chang X, Qian S, Liu C, Lord CC, Ahmed N, Lee CE, Lee S, Gautron L, Mitchell MC, Horton JD, Scherer PE, Elmquist JK.

Mol Metab. 2018 May 23. pii: S2212-8778(18)30014-0. doi: 10.1016/j.molmet.2018.05.015. [Epub ahead of print]

6.

Glucose-regulated protein 78 is essential for cardiac myocyte survival.

Wang X, Bi X, Zhang G, Deng Y, Luo X, Xu L, Scherer PE, Ferdous A, Fu G, Gillette TG, Lee AS, Jiang X, Wang ZV.

Cell Death Differ. 2018 Apr 17. doi: 10.1038/s41418-018-0109-4. [Epub ahead of print]

PMID:
29666470
7.

Differential glucose requirement in skin homeostasis and injury identifies a therapeutic target for psoriasis.

Zhang Z, Zi Z, Lee EE, Zhao J, Contreras DC, South AP, Abel ED, Chong BF, Vandergriff T, Hosler GA, Scherer PE, Mettlen M, Rathmell JC, DeBerardinis RJ, Wang RC.

Nat Med. 2018 May;24(5):617-627. doi: 10.1038/s41591-018-0003-0. Epub 2018 Apr 16.

PMID:
29662201
8.

New zoning laws enforced by glucagon.

Kusminski CM, Scherer PE.

Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):4308-4310. doi: 10.1073/pnas.1804203115. Epub 2018 Apr 9. No abstract available.

PMID:
29632201
9.

Specific Hepatic Sphingolipids Relate to Insulin Resistance, Oxidative Stress, and Inflammation in Nonalcoholic Steatohepatitis.

Apostolopoulou M, Gordillo R, Koliaki C, Gancheva S, Jelenik T, De Filippo E, Herder C, Markgraf D, Jankowiak F, Esposito I, Schlensak M, Scherer PE, Roden M.

Diabetes Care. 2018 Jun;41(6):1235-1243. doi: 10.2337/dc17-1318. Epub 2018 Mar 30.

PMID:
29602794
10.

Adipocyte Xbp1s overexpression drives uridine production and reduces obesity.

Deng Y, Wang ZV, Gordillo R, Zhu Y, Ali A, Zhang C, Wang X, Shao M, Zhang Z, Iyengar P, Gupta RK, Horton JD, Hill JA, Scherer PE.

Mol Metab. 2018 May;11:1-17. doi: 10.1016/j.molmet.2018.02.013. Epub 2018 Mar 2.

11.

PPARγ and its Role in Adipocyte Homeostasis and Thiazolidinedione-Mediated Insulin Sensitization.

Wang QA, Zhang F, Jiang L, Ye R, An Y, Shao M, Tao C, Gupta RK, Scherer PE.

Mol Cell Biol. 2018 Feb 26. pii: MCB.00677-17. doi: 10.1128/MCB.00677-17. [Epub ahead of print]

PMID:
29483301
12.

Hyaluronan in adipogenesis, adipose tissue physiology and systemic metabolism.

Zhu Y, Kruglikov IL, Akgul Y, Scherer PE.

Matrix Biol. 2018 Feb 16. pii: S0945-053X(17)30379-7. doi: 10.1016/j.matbio.2018.02.012. [Epub ahead of print] Review.

13.

Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity.

Ye R, Gordillo R, Shao M, Onodera T, Chen Z, Chen S, Lin X, SoRelle JA, Li X, Tang M, Keller MP, Kuliawat R, Attie AD, Gupta RK, Holland WL, Beutler B, Herz J, Scherer PE.

J Clin Invest. 2018 Mar 1;128(3):1178-1189. doi: 10.1172/JCI97702. Epub 2018 Feb 19.

14.

An Adipose Tissue Atlas: An Image-Guided Identification of Human-like BAT and Beige Depots in Rodents.

Zhang F, Hao G, Shao M, Nham K, An Y, Wang Q, Zhu Y, Kusminski CM, Hassan G, Gupta RK, Zhai Q, Sun X, Scherer PE, Oz OK.

Cell Metab. 2018 Jan 9;27(1):252-262.e3. doi: 10.1016/j.cmet.2017.12.004.

PMID:
29320705
15.

Adipose tissue: The dysfunctional adipocyte - a cancer cell's best friend.

Zhang Z, Scherer PE.

Nat Rev Endocrinol. 2018 Mar;14(3):132-134. doi: 10.1038/nrendo.2017.174. Epub 2018 Jan 5. No abstract available.

PMID:
29302078
16.

Conditional MitoTimer reporter mice for assessment of mitochondrial structure, oxidative stress, and mitophagy.

Wilson RJ, Drake JC, Cui D, Zhang M, Perry HM, Kashatus JA, Kusminski CM, Scherer PE, Kashatus DF, Okusa MD, Yan Z.

Mitochondrion. 2017 Dec 20. pii: S1567-7249(17)30196-4. doi: 10.1016/j.mito.2017.12.008. [Epub ahead of print]

17.

Acute loss of adipose tissue-derived adiponectin triggers immediate metabolic deterioration in mice.

Xia JY, Sun K, Hepler C, Ghaben AL, Gupta RK, An YA, Holland WL, Morley TS, Adams AC, Gordillo R, Kusminski CM, Scherer PE.

Diabetologia. 2018 Apr;61(4):932-941. doi: 10.1007/s00125-017-4516-8. Epub 2017 Dec 9.

PMID:
29224189
18.

Immunologic and endocrine functions of adipose tissue: implications for kidney disease.

Zhu Q, Scherer PE.

Nat Rev Nephrol. 2018 Feb;14(2):105-120. doi: 10.1038/nrneph.2017.157. Epub 2017 Dec 4. Review.

PMID:
29199276
19.

Nav1.8 neurons are involved in limiting acute phase responses to dietary fat.

Udit S, Burton M, Rutkowski JM, Lee S, Bookout AL, Scherer PE, Elmquist JK, Gautron L.

Mol Metab. 2017 Oct;6(10):1081-1091. doi: 10.1016/j.molmet.2017.07.012. Epub 2017 Aug 4. Review.

20.

Hepatic GALE Regulates Whole-Body Glucose Homeostasis by Modulating Tff3 Expression.

Zhu Y, Zhao S, Deng Y, Gordillo R, Ghaben AL, Shao M, Zhang F, Xu P, Li Y, Cao H, Zagnitko O, Scott DA, Gupta RK, Xing C, Zhang BB, Lin HV, Scherer PE.

Diabetes. 2017 Nov;66(11):2789-2799. doi: 10.2337/db17-0323. Epub 2017 Sep 6.

21.

General theory of skin reinforcement.

Kruglikov IL, Scherer PE.

PLoS One. 2017 Aug 10;12(8):e0182865. doi: 10.1371/journal.pone.0182865. eCollection 2017.

22.

MitoNEET-dependent formation of intermitochondrial junctions.

Vernay A, Marchetti A, Sabra A, Jauslin TN, Rosselin M, Scherer PE, Demaurex N, Orci L, Cosson P.

Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):8277-8282. doi: 10.1073/pnas.1706643114. Epub 2017 Jul 17.

23.

Retrograde Lymph Flow Leads to Chylothorax in Transgenic Mice with Lymphatic Malformations.

Nitschké M, Bell A, Karaman S, Amouzgar M, Rutkowski JM, Scherer PE, Alitalo K, McDonald DM.

Am J Pathol. 2017 Sep;187(9):1984-1997. doi: 10.1016/j.ajpath.2017.05.009. Epub 2017 Jul 3.

PMID:
28683257
24.

Adiponectin is an endogenous anti-fibrotic mediator and therapeutic target.

Marangoni RG, Masui Y, Fang F, Korman B, Lord G, Lee J, Lakota K, Wei J, Scherer PE, Otvos L, Yamauchi T, Kubota N, Kadowaki T, Asano Y, Sato S, Tourtellotte WG, Varga J.

Sci Rep. 2017 Jun 30;7(1):4397. doi: 10.1038/s41598-017-04162-1.

25.

Dapagliflozin suppresses glucagon signaling in rodent models of diabetes.

Wang MY, Yu X, Lee Y, McCorkle SK, Chen S, Li J, Wang ZV, Davidson JA, Scherer PE, Holland WL, Unger RH, Roth MG.

Proc Natl Acad Sci U S A. 2017 Jun 20;114(25):6611-6616. doi: 10.1073/pnas.1705845114. Epub 2017 Jun 5.

26.

Cyclin D1 Restrains Oncogene-Induced Autophagy by Regulating the AMPK-LKB1 Signaling Axis.

Casimiro MC, Di Sante G, Di Rocco A, Loro E, Pupo C, Pestell TG, Bisetto S, Velasco-Velázquez MA, Jiao X, Li Z, Kusminski CM, Seifert EL, Wang C, Ly D, Zheng B, Shen CH, Scherer PE, Pestell RG.

Cancer Res. 2017 Jul 1;77(13):3391-3405. doi: 10.1158/0008-5472.CAN-16-0425. Epub 2017 May 18.

27.

Adipocyte-myofibroblast transition as a possible pathophysiological step in androgenetic alopecia.

Kruglikov IL, Scherer PE.

Exp Dermatol. 2017 Jun;26(6):522-523. doi: 10.1111/exd.13379.

PMID:
28482134
28.

Angiopoietin-2 in white adipose tissue improves metabolic homeostasis through enhanced angiogenesis.

An YA, Sun K, Joffin N, Zhang F, Deng Y, Donzé O, Kusminski CM, Scherer PE.

Elife. 2017 Mar 29;6. pii: e24071. doi: 10.7554/eLife.24071.

29.

Structural biology: Receptors grease the metabolic wheels.

Holland WL, Scherer PE.

Nature. 2017 Apr 6;544(7648):42-44. doi: 10.1038/nature21900. Epub 2017 Mar 22. No abstract available.

PMID:
28329767
30.

Short-Term Versus Long-Term Effects of Adipocyte Toll-Like Receptor 4 Activation on Insulin Resistance in Male Mice.

Tao C, Holland WL, Wang QA, Shao M, Jia L, Sun K, Lin X, Kuo YC, Johnson JA, Gordillo R, Elmquist JK, Scherer PE.

Endocrinology. 2017 May 1;158(5):1260-1270. doi: 10.1210/en.2017-00024.

31.

An adipo-biliary-uridine axis that regulates energy homeostasis.

Deng Y, Wang ZV, Gordillo R, An Y, Zhang C, Liang Q, Yoshino J, Cautivo KM, De Brabander J, Elmquist JK, Horton JD, Hill JA, Klein S, Scherer PE.

Science. 2017 Mar 17;355(6330). pii: eaaf5375. doi: 10.1126/science.aaf5375. Epub 2017 Mar 16.

32.

Inducible overexpression of adiponectin receptors highlight the roles of adiponectin-induced ceramidase signaling in lipid and glucose homeostasis.

Holland WL, Xia JY, Johnson JA, Sun K, Pearson MJ, Sharma AX, Quittner-Strom E, Tippetts TS, Gordillo R, Scherer PE.

Mol Metab. 2017 Jan 12;6(3):267-275. doi: 10.1016/j.molmet.2017.01.002. eCollection 2017 Mar.

33.

VEGF-A-Expressing Adipose Tissue Shows Rapid Beiging and Enhanced Survival After Transplantation and Confers IL-4-Independent Metabolic Improvements.

Park J, Kim M, Sun K, An YA, Gu X, Scherer PE.

Diabetes. 2017 Jun;66(6):1479-1490. doi: 10.2337/db16-1081. Epub 2017 Mar 2.

34.

Pas de Deux: Glucagon and Thyroid Hormone Moving in Perfect Synchrony.

Ghaben AL, Scherer PE.

Circ Res. 2017 Mar 3;120(5):762-764. doi: 10.1161/CIRCRESAHA.117.310452. Review. No abstract available.

35.

microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism.

Hajarnis S, Lakhia R, Yheskel M, Williams D, Sorourian M, Liu X, Aboudehen K, Zhang S, Kersjes K, Galasso R, Li J, Kaimal V, Lockton S, Davis S, Flaten A, Johnson JA, Holland WL, Kusminski CM, Scherer PE, Harris PC, Trudel M, Wallace DP, Igarashi P, Lee EC, Androsavich JR, Patel V.

Nat Commun. 2017 Feb 16;8:14395. doi: 10.1038/ncomms14395.

36.

The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis.

Crewe C, An YA, Scherer PE.

J Clin Invest. 2017 Jan 3;127(1):74-82. doi: 10.1172/JCI88883. Epub 2017 Jan 3. Review.

37.

Alterations in pancreatic β cell function and Trypanosoma cruzi infection: evidence from human and animal studies.

Dufurrena Q, Amjad FM, Scherer PE, Weiss LM, Nagajyothi J, Roth J, Tanowitz HB, Kuliawat R.

Parasitol Res. 2017 Mar;116(3):827-838. doi: 10.1007/s00436-016-5350-5. Epub 2016 Dec 24. Review.

38.

Adipose Tissue: A Safe Haven for Parasites?

Tanowitz HB, Scherer PE, Mota MM, Figueiredo LM.

Trends Parasitol. 2017 Apr;33(4):276-284. doi: 10.1016/j.pt.2016.11.008. Epub 2016 Dec 19. Review.

39.

Fasting selectively blocks development of acute lymphoblastic leukemia via leptin-receptor upregulation.

Lu Z, Xie J, Wu G, Shen J, Collins R, Chen W, Kang X, Luo M, Zou Y, Huang LJ, Amatruda JF, Slone T, Winick N, Scherer PE, Zhang CC.

Nat Med. 2017 Jan;23(1):79-90. doi: 10.1038/nm.4252. Epub 2016 Dec 12.

PMID:
27941793
40.

Serum Amyloid A3 Gene Expression in Adipocytes is an Indicator of the Interaction with Macrophages.

Sanada Y, Yamamoto T, Satake R, Yamashita A, Kanai S, Kato N, van de Loo FA, Nishimura F, Scherer PE, Yanaka N.

Sci Rep. 2016 Dec 8;6:38697. doi: 10.1038/srep38697.

41.

Adiponectin alters renal calcium and phosphate excretion through regulation of klotho expression.

Rutkowski JM, Pastor J, Sun K, Park SK, Bobulescu IA, Chen CT, Moe OW, Scherer PE.

Kidney Int. 2017 Feb;91(2):324-337. doi: 10.1016/j.kint.2016.09.016. Epub 2016 Nov 30.

42.

SF-1 expression in the hypothalamus is required for beneficial metabolic effects of exercise.

Fujikawa T, Castorena CM, Pearson M, Kusminski CM, Ahmed N, Battiprolu PK, Kim KW, Lee S, Hill JA, Scherer PE, Holland WL, Elmquist JK.

Elife. 2016 Nov 22;5. pii: e18206. doi: 10.7554/eLife.18206.

43.

Adipose HIF-1α causes obesity by suppressing brown adipose tissue thermogenesis.

Jun JC, Devera R, Unnikrishnan D, Shin MK, Bevans-Fonti S, Yao Q, Rathore A, Younas H, Halberg N, Scherer PE, Polotsky VY.

J Mol Med (Berl). 2017 Mar;95(3):287-297. doi: 10.1007/s00109-016-1480-6. Epub 2016 Oct 14.

45.

Adiponectin potentiates the acute effects of leptin in arcuate Pomc neurons.

Sun J, Gao Y, Yao T, Huang Y, He Z, Kong X, Yu KJ, Wang RT, Guo H, Yan J, Chang Y, Chen H, Scherer PE, Liu T, Williams KW.

Mol Metab. 2016 Aug 18;5(10):882-891. doi: 10.1016/j.molmet.2016.08.007. eCollection 2016 Oct.

46.

Sex differences in adult rat insulin and glucose responses to arginine: programming effects of neonatal separation, hypoxia, and hypothermia.

Gehrand AL, Hoeynck B, Jablonski M, Leonovicz C, Ye R, Scherer PE, Raff H.

Physiol Rep. 2016 Sep;4(18). pii: e12972.

47.

Connexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals.

Zhu Y, Gao Y, Tao C, Shao M, Zhao S, Huang W, Yao T, Johnson JA, Liu T, Cypess AM, Gupta O, Holland WL, Gupta RK, Spray DC, Tanowitz HB, Cao L, Lynes MD, Tseng YH, Elmquist JK, Williams KW, Lin HV, Scherer PE.

Cell Metab. 2016 Sep 13;24(3):420-433. doi: 10.1016/j.cmet.2016.08.005.

48.

Adiponectin: Just Along for the Ride?

Turer AT, Scherer PE.

Circ Res. 2016 Jul 22;119(3):407-8. doi: 10.1161/CIRCRESAHA.116.309226. No abstract available.

49.

Adiponectin protects against incident hypertension independent of body fat distribution: observations from the Dallas Heart Study.

Peri-Okonny PA, Ayers C, Maalouf N, Das SR, de Lemos JA, Berry JD, Turer AT, Neeland IJ, Scherer PE, Vongpatanasin W.

Diabetes Metab Res Rev. 2017 Feb;33(2). doi: 10.1002/dmrr.2840. Epub 2016 Aug 18.

50.

Skin aging: are adipocytes the next target?

Kruglikov IL, Scherer PE.

Aging (Albany NY). 2016 Jul;8(7):1457-69. doi: 10.18632/aging.100999. Review.

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