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Items: 23


Programming of CD8 T Cell Quantity and Polyfunctionality by Direct IL-1 Signals.

Sarkar S, Yuzefpolskiy Y, Xiao H, Baumann FM, Yim S, Lee DJ, Schenten D, Kalia V.

J Immunol. 2018 Dec 15;201(12):3641-3650. doi: 10.4049/jimmunol.1800906. Epub 2018 Nov 19.


Rapid fucosylation of intestinal epithelium sustains host-commensal symbiosis in sickness.

Pickard JM, Maurice CF, Kinnebrew MA, Abt MC, Schenten D, Golovkina TV, Bogatyrev SR, Ismagilov RF, Pamer EG, Turnbaugh PJ, Chervonsky AV.

Nature. 2014 Oct 30;514(7524):638-41. doi: 10.1038/nature13823. Epub 2014 Oct 1.


T cell-intrinsic role of IL-6 signaling in primary and memory responses.

Nish SA, Schenten D, Wunderlich FT, Pope SD, Gao Y, Hoshi N, Yu S, Yan X, Lee HK, Pasman L, Brodsky I, Yordy B, Zhao H, Brüning J, Medzhitov R.

Elife. 2014 May 19;3:e01949. doi: 10.7554/eLife.01949.


A20-deficient mast cells exacerbate inflammatory responses in vivo.

Heger K, Fierens K, Vahl JC, Aszodi A, Peschke K, Schenten D, Hammad H, Beyaert R, Saur D, van Loo G, Roers A, Lambrecht BN, Kool M, Schmidt-Supprian M.

PLoS Biol. 2014 Jan;12(1):e1001762. doi: 10.1371/journal.pbio.1001762. Epub 2014 Jan 14.


Signaling through the adaptor molecule MyD88 in CD4+ T cells is required to overcome suppression by regulatory T cells.

Schenten D, Nish SA, Yu S, Yan X, Lee HK, Brodsky I, Pasman L, Yordy B, Wunderlich FT, Brüning JC, Zhao H, Medzhitov R.

Immunity. 2014 Jan 16;40(1):78-90. doi: 10.1016/j.immuni.2013.10.023. Erratum in: Immunity. 2014 May 15;40(5):814.


Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective immunity.

Palm NW, Rosenstein RK, Yu S, Schenten DD, Florsheim E, Medzhitov R.

Immunity. 2013 Nov 14;39(5):976-85. doi: 10.1016/j.immuni.2013.10.006. Epub 2013 Oct 24.


Signals via the adaptor MyD88 in B cells and DCs make distinct and synergistic contributions to immune activation and tissue damage in lupus.

Teichmann LL, Schenten D, Medzhitov R, Kashgarian M, Shlomchik MJ.

Immunity. 2013 Mar 21;38(3):528-40. doi: 10.1016/j.immuni.2012.11.017. Epub 2013 Mar 14.


MyD88 signalling in colonic mononuclear phagocytes drives colitis in IL-10-deficient mice.

Hoshi N, Schenten D, Nish SA, Walther Z, Gagliani N, Flavell RA, Reizis B, Shen Z, Fox JG, Iwasaki A, Medzhitov R.

Nat Commun. 2012;3:1120. doi: 10.1038/ncomms2113.


IL-1R-MyD88 signaling in keratinocyte transformation and carcinogenesis.

Cataisson C, Salcedo R, Hakim S, Moffitt BA, Wright L, Yi M, Stephens R, Dai RM, Lyakh L, Schenten D, Yuspa HS, Trinchieri G.

J Exp Med. 2012 Aug 27;209(9):1689-702. doi: 10.1084/jem.20101355. Epub 2012 Aug 20.


DNA polymerase ζ generates tandem mutations in immunoglobulin variable regions.

Saribasak H, Maul RW, Cao Z, Yang WW, Schenten D, Kracker S, Gearhart PJ.

J Exp Med. 2012 Jun 4;209(6):1075-81. doi: 10.1084/jem.20112234. Epub 2012 May 21.


Langerhans cells require MyD88-dependent signals for Candida albicans response but not for contact hypersensitivity or migration.

Haley K, Igyártó BZ, Ortner D, Bobr A, Kashem S, Schenten D, Kaplan DH.

J Immunol. 2012 May 1;188(9):4334-9. doi: 10.4049/jimmunol.1102759. Epub 2012 Mar 21.


Aging enhances the basal production of IL-6 and CCL2 in vascular smooth muscle cells.

Song Y, Shen H, Schenten D, Shan P, Lee PJ, Goldstein DR.

Arterioscler Thromb Vasc Biol. 2012 Jan;32(1):103-9. doi: 10.1161/ATVBAHA.111.236349. Epub 2011 Oct 27.


The control of adaptive immune responses by the innate immune system.

Schenten D, Medzhitov R.

Adv Immunol. 2011;109:87-124. doi: 10.1016/B978-0-12-387664-5.00003-0. Review.


B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice.

Chu Y, Vahl JC, Kumar D, Heger K, Bertossi A, Wójtowicz E, Soberon V, Schenten D, Mack B, Reutelshöfer M, Beyaert R, Amann K, van Loo G, Schmidt-Supprian M.

Blood. 2011 Feb 17;117(7):2227-36. doi: 10.1182/blood-2010-09-306019. Epub 2010 Nov 18.


MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity.

Kleinridders A, Schenten D, Könner AC, Belgardt BF, Mauer J, Okamura T, Wunderlich FT, Medzhitov R, Brüning JC.

Cell Metab. 2009 Oct;10(4):249-59. doi: 10.1016/j.cmet.2009.08.013.


Pol zeta ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability.

Schenten D, Kracker S, Esposito G, Franco S, Klein U, Murphy M, Alt FW, Rajewsky K.

J Exp Med. 2009 Feb 16;206(2):477-90. doi: 10.1084/jem.20080669. Epub 2009 Feb 9.


DNA polymerase kappa deficiency does not affect somatic hypermutation in mice.

Schenten D, Gerlach VL, Guo C, Velasco-Miguel S, Hladik CL, White CL, Friedberg EC, Rajewsky K, Esposito G.

Eur J Immunol. 2002 Nov;32(11):3152-60.


Determinants of neutralization resistance in the envelope glycoproteins of a simian-human immunodeficiency virus passaged in vivo.

Etemad-Moghadam B, Sun Y, Nicholson EK, Karlsson GB, Schenten D, Sodroski J.

J Virol. 1999 Oct;73(10):8873-9.


Effects of soluble CD4 on simian immunodeficiency virus infection of CD4-positive and CD4-negative cells.

Schenten D, Marcon L, Karlsson GB, Parolin C, Kodama T, Gerard N, Sodroski J.

J Virol. 1999 Jul;73(7):5373-80.


The envelope glycoprotein ectodomains determine the efficiency of CD4+ T lymphocyte depletion in simian-human immunodeficiency virus-infected macaques.

Karlsson GB, Halloran M, Schenten D, Lee J, Racz P, Tenner-Racz K, Manola J, Gelman R, Etemad-Moghadam B, Desjardins E, Wyatt R, Gerard NP, Marcon L, Margolin D, Fanton J, Axthelm MK, Letvin NL, Sodroski J.

J Exp Med. 1998 Sep 21;188(6):1159-71.


Characterization of simian-human immunodeficiency virus envelope glycoprotein epitopes recognized by neutralizing antibodies from infected monkeys.

Etemad-Moghadam B, Karlsson GB, Halloran M, Sun Y, Schenten D, Fernandes M, Letvin NL, Sodroski J.

J Virol. 1998 Oct;72(10):8437-45.

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