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Items: 1 to 50 of 149

1.

Habituation Learning Is a Widely Affected Mechanism in Drosophila Models of Intellectual Disability and Autism Spectrum Disorders.

Fenckova M, Blok LER, Asztalos L, Goodman DP, Cizek P, Singgih EL, Glennon JC, IntHout J, Zweier C, Eichler EE, von Reyn CR, Bernier RA, Asztalos Z, Schenck A.

Biol Psychiatry. 2019 Aug 15;86(4):294-305. doi: 10.1016/j.biopsych.2019.04.029. Epub 2019 May 9.

2.

Intellectual disability and autism spectrum disorders 'on the fly': insights from Drosophila.

Coll-Tané M, Krebbers A, Castells-Nobau A, Zweier C, Schenck A.

Dis Model Mech. 2019 May 13;12(5). pii: dmm039180. doi: 10.1242/dmm.039180. Review.

3.

Molecular Recognition of Structures Is Key in the Polymerization of Patterned Barnacle Adhesive Sequences.

So CR, Yates EA, Estrella LA, Fears KP, Schenck AM, Yip CM, Wahl KJ.

ACS Nano. 2019 May 28;13(5):5172-5183. doi: 10.1021/acsnano.8b09194. Epub 2019 Apr 26.

PMID:
30986028
4.

A Drosophila Mitochondrial Complex I Deficiency Phenotype Array.

Foriel S, Renkema GH, Lasarzewski Y, Berkhout J, Rodenburg RJ, Smeitink JAM, Beyrath J, Schenck A.

Front Genet. 2019 Mar 27;10:245. doi: 10.3389/fgene.2019.00245. eCollection 2019.

5.

The histone methyltransferase G9a regulates tolerance to oxidative stress-induced energy consumption.

Riahi H, Brekelmans C, Foriel S, Merkling SH, Lyons TA, Itskov PM, Kleefstra T, Ribeiro C, van Rij RP, Kramer JM, Schenck A.

PLoS Biol. 2019 Mar 12;17(3):e2006146. doi: 10.1371/journal.pbio.2006146. eCollection 2019 Mar.

6.

Building capacity for Public Health 3.0: introducing implementation science into an MPH curriculum.

Ramaswamy R, Mosnier J, Reed K, Powell BJ, Schenck AP.

Implement Sci. 2019 Feb 28;14(1):18. doi: 10.1186/s13012-019-0866-6.

7.

Peroxisome-associated Sgroppino links fat metabolism with survival after RNA virus infection in Drosophila.

Merkling SH, Riahi H, Overheul GJ, Schenck A, van Rij RP.

Sci Rep. 2019 Feb 14;9(1):2065. doi: 10.1038/s41598-019-38559-x.

8.

Conserved regulation of neurodevelopmental processes and behavior by FoxP in Drosophila.

Castells-Nobau A, Eidhof I, Fenckova M, Brenman-Suttner DB, Scheffer-de Gooyert JM, Christine S, Schellevis RL, van der Laan K, Quentin C, van Ninhuijs L, Hofmann F, Ejsmont R, Fisher SE, Kramer JM, Sigrist SJ, Simon AF, Schenck A.

PLoS One. 2019 Feb 12;14(2):e0211652. doi: 10.1371/journal.pone.0211652. eCollection 2019.

9.

Integrative network and brain expression analysis reveals mechanistic modules in ataxia.

Eidhof I, van de Warrenburg BP, Schenck A.

J Med Genet. 2019 May;56(5):283-292. doi: 10.1136/jmedgenet-2018-105703. Epub 2018 Dec 27.

10.

Cross-species models of attention-deficit/hyperactivity disorder and autism spectrum disorder: lessons from CNTNAP2, ADGRL3, and PARK2.

Dalla Vecchia E, Mortimer N, Palladino VS, Kittel-Schneider S, Lesch KP, Reif A, Schenck A, Norton WHJ.

Psychiatr Genet. 2019 Feb;29(1):1-17. doi: 10.1097/YPG.0000000000000211. Review.

PMID:
30376466
11.

SnapShot: Biology of Genetic Ataxias.

Eidhof I, van de Warrenburg BP, Schenck A.

Cell. 2018 Oct 18;175(3):890-890.e1. doi: 10.1016/j.cell.2018.10.017. Review.

PMID:
30340048
12.

Senior PharmAssist: Less Hospital Use with Enrollment in an Innovative Community-Based Program.

Herity LB, Upchurch G, Schenck AP.

J Am Geriatr Soc. 2018 Dec;66(12):2394-2400. doi: 10.1111/jgs.15617. Epub 2018 Oct 11.

PMID:
30306540
13.

Proceedings of the fifth international RASopathies symposium: When development and cancer intersect.

Rauen KA, Schoyer L, Schill L, Stronach B, Albeck J, Andresen BS, Cavé H, Ellis M, Fruchtman SM, Gelb BD, Gibson CC, Gripp K, Hefner E, Huang WYC, Itkin M, Kerr B, Linardic CM, McMahon M, Oberlander B, Perlstein E, Ratner N, Rogers L, Schenck A, Shankar S, Shvartsman S, Stevenson DA, Stites EC, Stork PJS, Sun C, Therrien M, Ullian EM, Widemann BC, Yeh E, Zampino G, Zenker M, Timmer W, McCormick F.

Am J Med Genet A. 2018 Dec;176(12):2924-2929. doi: 10.1002/ajmg.a.40632. Epub 2018 Oct 10.

PMID:
30302932
14.

GDAP2 mutations implicate susceptibility to cellular stress in a new form of cerebellar ataxia.

Eidhof I, Baets J, Kamsteeg EJ, Deconinck T, van Ninhuijs L, Martin JJ, Schüle R, Züchner S, De Jonghe P, Schenck A, van de Warrenburg BP.

Brain. 2018 Sep 1;141(9):2592-2604. doi: 10.1093/brain/awy198.

PMID:
30084953
15.

Feeding difficulties, a key feature of the Drosophila NDUFS4 mitochondrial disease model.

Foriel S, Beyrath J, Eidhof I, Rodenburg RJ, Schenck A, Smeitink JAM.

Dis Model Mech. 2018 Mar 27;11(3). pii: dmm032482. doi: 10.1242/dmm.032482.

16.

High-throughput Analysis of Locomotor Behavior in the Drosophila Island Assay.

Eidhof I, Fenckova M, Elurbe DM, van de Warrenburg B, Castells Nobau A, Schenck A.

J Vis Exp. 2017 Nov 5;(129). doi: 10.3791/55892.

17.

Functional convergence of histone methyltransferases EHMT1 and KMT2C involved in intellectual disability and autism spectrum disorder.

Koemans TS, Kleefstra T, Chubak MC, Stone MH, Reijnders MRF, de Munnik S, Willemsen MH, Fenckova M, Stumpel CTRM, Bok LA, Sifuentes Saenz M, Byerly KA, Baughn LB, Stegmann APA, Pfundt R, Zhou H, van Bokhoven H, Schenck A, Kramer JM.

PLoS Genet. 2017 Oct 25;13(10):e1006864. doi: 10.1371/journal.pgen.1006864. eCollection 2017 Oct.

18.

Drosophila Courtship Conditioning As a Measure of Learning and Memory.

Koemans TS, Oppitz C, Donders RAT, van Bokhoven H, Schenck A, Keleman K, Kramer JM.

J Vis Exp. 2017 Jun 5;(124). doi: 10.3791/55808.

19.

Two Algorithms for High-throughput and Multi-parametric Quantification of Drosophila Neuromuscular Junction Morphology.

Castells-Nobau A, Nijhof B, Eidhof I, Wolf L, Scheffer-de Gooyert JM, Monedero I, Torroja L, van der Laak JAWM, Schenck A.

J Vis Exp. 2017 May 3;(123). doi: 10.3791/55395.

20.

Targeted sequencing identifies 91 neurodevelopmental-disorder risk genes with autism and developmental-disability biases.

Stessman HA, Xiong B, Coe BP, Wang T, Hoekzema K, Fenckova M, Kvarnung M, Gerdts J, Trinh S, Cosemans N, Vives L, Lin J, Turner TN, Santen G, Ruivenkamp C, Kriek M, van Haeringen A, Aten E, Friend K, Liebelt J, Barnett C, Haan E, Shaw M, Gecz J, Anderlid BM, Nordgren A, Lindstrand A, Schwartz C, Kooy RF, Vandeweyer G, Helsmoortel C, Romano C, Alberti A, Vinci M, Avola E, Giusto S, Courchesne E, Pramparo T, Pierce K, Nalabolu S, Amaral DG, Scheffer IE, Delatycki MB, Lockhart PJ, Hormozdiari F, Harich B, Castells-Nobau A, Xia K, Peeters H, Nordenskjöld M, Schenck A, Bernier RA, Eichler EE.

Nat Genet. 2017 Apr;49(4):515-526. doi: 10.1038/ng.3792. Epub 2017 Feb 13.

21.

A homozygous FITM2 mutation causes a deafness-dystonia syndrome with motor regression and signs of ichthyosis and sensory neuropathy.

Zazo Seco C, Castells-Nobau A, Joo SH, Schraders M, Foo JN, van der Voet M, Velan SS, Nijhof B, Oostrik J, de Vrieze E, Katana R, Mansoor A, Huynen M, Szklarczyk R, Oti M, Tranebjærg L, van Wijk E, Scheffer-de Gooyert JM, Siddique S, Baets J, de Jonghe P, Kazmi SA, Sadananthan SA, van de Warrenburg BP, Khor CC, Göpfert MC, Qamar R, Schenck A, Kremer H, Siddiqi S.

Dis Model Mech. 2017 Feb 1;10(2):105-118. doi: 10.1242/dmm.026476. Epub 2016 Dec 15.

22.

National Institutes of Health Pathways to Prevention Workshop: Advancing Research to Prevent Youth Suicide.

Little TD, Roche KM, Chow SM, Schenck AP, Byam LA.

Ann Intern Med. 2016 Dec 6;165(11):795-799. doi: 10.7326/M16-1568. Epub 2016 Oct 4.

PMID:
27699417
23.

BOD1 Is Required for Cognitive Function in Humans and Drosophila.

Esmaeeli-Nieh S, Fenckova M, Porter IM, Motazacker MM, Nijhof B, Castells-Nobau A, Asztalos Z, Weißmann R, Behjati F, Tzschach A, Felbor U, Scherthan H, Sayfati SM, Ropers HH, Kahrizi K, Najmabadi H, Swedlow JR, Schenck A, Kuss AW.

PLoS Genet. 2016 May 11;12(5):e1006022. doi: 10.1371/journal.pgen.1006022. eCollection 2016 May.

24.

A New Fiji-Based Algorithm That Systematically Quantifies Nine Synaptic Parameters Provides Insights into Drosophila NMJ Morphometry.

Nijhof B, Castells-Nobau A, Wolf L, Scheffer-de Gooyert JM, Monedero I, Torroja L, Coromina L, van der Laak JA, Schenck A.

PLoS Comput Biol. 2016 Mar 21;12(3):e1004823. doi: 10.1371/journal.pcbi.1004823. eCollection 2016 Mar.

25.

Disruption of POGZ Is Associated with Intellectual Disability and Autism Spectrum Disorders.

Stessman HAF, Willemsen MH, Fenckova M, Penn O, Hoischen A, Xiong B, Wang T, Hoekzema K, Vives L, Vogel I, Brunner HG, van der Burgt I, Ockeloen CW, Schuurs-Hoeijmakers JH, Klein Wassink-Ruiter JS, Stumpel C, Stevens SJC, Vles HS, Marcelis CM, van Bokhoven H, Cantagrel V, Colleaux L, Nicouleau M, Lyonnet S, Bernier RA, Gerdts J, Coe BP, Romano C, Alberti A, Grillo L, Scuderi C, Nordenskjöld M, Kvarnung M, Guo H, Xia K, Piton A, Gerard B, Genevieve D, Delobel B, Lehalle D, Perrin L, Prieur F, Thevenon J, Gecz J, Shaw M, Pfundt R, Keren B, Jacquette A, Schenck A, Eichler EE, Kleefstra T.

Am J Hum Genet. 2016 Mar 3;98(3):541-552. doi: 10.1016/j.ajhg.2016.02.004.

26.

De novo loss-of-function mutations in WAC cause a recognizable intellectual disability syndrome and learning deficits in Drosophila.

Lugtenberg D, Reijnders MR, Fenckova M, Bijlsma EK, Bernier R, van Bon BW, Smeets E, Vulto-van Silfhout AT, Bosch D, Eichler EE, Mefford HC, Carvill GL, Bongers EM, Schuurs-Hoeijmakers JH, Ruivenkamp CA, Santen GW, van den Maagdenberg AM, Peeters-Scholte CM, Kuenen S, Verstreken P, Pfundt R, Yntema HG, de Vries PF, Veltman JA, Hoischen A, Gilissen C, de Vries BB, Schenck A, Kleefstra T, Vissers LE.

Eur J Hum Genet. 2016 Aug;24(8):1145-53. doi: 10.1038/ejhg.2015.282. Epub 2016 Jan 13.

27.

Systematic Phenomics Analysis Deconvolutes Genes Mutated in Intellectual Disability into Biologically Coherent Modules.

Kochinke K, Zweier C, Nijhof B, Fenckova M, Cizek P, Honti F, Keerthikumar S, Oortveld MA, Kleefstra T, Kramer JM, Webber C, Huynen MA, Schenck A.

Am J Hum Genet. 2016 Jan 7;98(1):149-64. doi: 10.1016/j.ajhg.2015.11.024.

28.

Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration.

Dubos A, Castells-Nobau A, Meziane H, Oortveld MA, Houbaert X, Iacono G, Martin C, Mittelhaeuser C, Lalanne V, Kramer JM, Bhukel A, Quentin C, Slabbert J, Verstreken P, Sigrist SJ, Messaddeq N, Birling MC, Selloum M, Stunnenberg HG, Humeau Y, Schenck A, Herault Y.

Hum Mol Genet. 2015 Dec 1;24(23):6736-55. doi: 10.1093/hmg/ddv380. Epub 2015 Sep 16.

29.

Converging evidence does not support GIT1 as an ADHD risk gene.

Klein M, van der Voet M, Harich B, van Hulzen KJ, Onnink AM, Hoogman M, Guadalupe T, Zwiers M, Groothuismink JM, Verberkt A, Nijhof B, Castells-Nobau A, Faraone SV, Buitelaar JK, Schenck A, Arias-Vasquez A, Franke B; Psychiatric Genomics Consortium ADHD Working Group.

Am J Med Genet B Neuropsychiatr Genet. 2015 Sep;168(6):492-507. doi: 10.1002/ajmg.b.32327. Epub 2015 Jun 10.

PMID:
26061966
30.

ADHD-associated dopamine transporter, latrophilin and neurofibromin share a dopamine-related locomotor signature in Drosophila.

van der Voet M, Harich B, Franke B, Schenck A.

Mol Psychiatry. 2016 Apr;21(4):565-73. doi: 10.1038/mp.2015.55. Epub 2015 May 12.

31.

The epigenetic regulator G9a mediates tolerance to RNA virus infection in Drosophila.

Merkling SH, Bronkhorst AW, Kramer JM, Overheul GJ, Schenck A, Van Rij RP.

PLoS Pathog. 2015 Apr 16;11(4):e1004692. doi: 10.1371/journal.ppat.1004692. eCollection 2015 Apr.

32.

Building the evidence for decision-making: the relationship between local public health capacity and community mortality.

Schenck AP, Meyer AM, Kuo TM, Cilenti D.

Am J Public Health. 2015 Apr;105 Suppl 2:S211-6. doi: 10.2105/AJPH.2014.302500. Epub 2015 Feb 17.

33.

Mitochondrial diseases: Drosophila melanogaster as a model to evaluate potential therapeutics.

Foriel S, Willems P, Smeitink J, Schenck A, Beyrath J.

Int J Biochem Cell Biol. 2015 Jun;63:60-5. doi: 10.1016/j.biocel.2015.01.024. Epub 2015 Feb 7. Review.

PMID:
25666557
34.

Physical Activity Levels During Acute Inpatient Admission After Hip Fracture are Very Low.

Davenport SJ, Arnold M, Hua C, Schenck A, Batten S, Taylor NF.

Physiother Res Int. 2015 Sep;20(3):174-81. doi: 10.1002/pri.1616. Epub 2014 Dec 4.

PMID:
25475700
35.

Effects of performance improvement programs on preparedness capacities.

Davis MV, Bevc CA, Schenck AP.

Public Health Rep. 2014;129 Suppl 4:19-27.

36.

Comparative effectiveness of follow-up imaging approaches in pancreatic cancer.

Reeder-Hayes KE, Freburger J, Feaganes J, Peacock Hinton S, Henderson LM, Massing M, Schenck AP, Stearns SC, Carpenter WR, Chen RC, Khandani AH.

J Comp Eff Res. 2014 Sep;3(5):491-502. doi: 10.2217/cer.14.35.

PMID:
25350801
37.

Altered GPM6A/M6 dosage impairs cognition and causes phenotypes responsive to cholesterol in human and Drosophila.

Gregor A, Kramer JM, van der Voet M, Schanze I, Uebe S, Donders R, Reis A, Schenck A, Zweier C.

Hum Mutat. 2014 Dec;35(12):1495-505. doi: 10.1002/humu.22697.

PMID:
25224183
38.

Declining trends in local health department preparedness capacities.

Davis MV, Bevc CA, Schenck AP.

Am J Public Health. 2014 Nov;104(11):2233-8. doi: 10.2105/AJPH.2014.302159. Epub 2014 Sep 11.

39.

Affecting African American men's prostate cancer screening decision-making through a mobile tablet-mediated intervention.

Sultan DH, Rivers BM, Osongo BO, Wilson DS, Schenck A, Carvajal R, Rivers D, Roetzheim R, Green BL.

J Health Care Poor Underserved. 2014 Aug;25(3):1262-77. doi: 10.1353/hpu.2014.0148.

40.

Quality measures for hospice and palliative care: piloting the PEACE measures.

Schenck AP, Rokoske FS, Durham D, Cagle JG, Hanson LC.

J Palliat Med. 2014 Jul;17(7):769-75. doi: 10.1089/jpm.2013.0652. Epub 2014 Jun 12.

41.

Genome sequencing identifies major causes of severe intellectual disability.

Gilissen C, Hehir-Kwa JY, Thung DT, van de Vorst M, van Bon BW, Willemsen MH, Kwint M, Janssen IM, Hoischen A, Schenck A, Leach R, Klein R, Tearle R, Bo T, Pfundt R, Yntema HG, de Vries BB, Kleefstra T, Brunner HG, Vissers LE, Veltman JA.

Nature. 2014 Jul 17;511(7509):344-7. doi: 10.1038/nature13394. Epub 2014 Jun 4.

PMID:
24896178
42.

Drosophila models of early onset cognitive disorders and their clinical applications.

van der Voet M, Nijhof B, Oortveld MA, Schenck A.

Neurosci Biobehav Rev. 2014 Oct;46 Pt 2:326-42. doi: 10.1016/j.neubiorev.2014.01.013. Epub 2014 Mar 21. Review.

43.

The genetics of cognitive epigenetics.

Kleefstra T, Schenck A, Kramer JM, van Bokhoven H.

Neuropharmacology. 2014 May;80:83-94. doi: 10.1016/j.neuropharm.2013.12.025. Epub 2014 Jan 13. Review.

PMID:
24434855
44.

Ubiquitin ligase HUWE1 regulates axon branching through the Wnt/β-catenin pathway in a Drosophila model for intellectual disability.

Vandewalle J, Langen M, Zschätzsch M, Nijhof B, Kramer JM, Brems H, Bauters M, Lauwers E, Srahna M, Marynen P, Verstreken P, Schenck A, Hassan BA, Froyen G.

PLoS One. 2013 Nov 26;8(11):e81791. doi: 10.1371/journal.pone.0081791. eCollection 2013. Erratum in: PLoS One. 2014;9(1). doi:10.1371/annotation/5a4ac42e-a148-4a89-b148-e47de0d72d16. Zschaetzsch, Marlen [corrected to Zschätzsch, Marlen].

45.

Human intellectual disability genes form conserved functional modules in Drosophila.

Oortveld MA, Keerthikumar S, Oti M, Nijhof B, Fernandes AC, Kochinke K, Castells-Nobau A, van Engelen E, Ellenkamp T, Eshuis L, Galy A, van Bokhoven H, Habermann B, Brunner HG, Zweier C, Verstreken P, Huynen MA, Schenck A.

PLoS Genet. 2013 Oct;9(10):e1003911. doi: 10.1371/journal.pgen.1003911. Epub 2013 Oct 31.

46.

Restoring polyamines protects from age-induced memory impairment in an autophagy-dependent manner.

Gupta VK, Scheunemann L, Eisenberg T, Mertel S, Bhukel A, Koemans TS, Kramer JM, Liu KS, Schroeder S, Stunnenberg HG, Sinner F, Magnes C, Pieber TR, Dipt S, Fiala A, Schenck A, Schwaerzel M, Madeo F, Sigrist SJ.

Nat Neurosci. 2013 Oct;16(10):1453-60. doi: 10.1038/nn.3512. Epub 2013 Sep 1.

PMID:
23995066
47.

GATAD2B loss-of-function mutations cause a recognisable syndrome with intellectual disability and are associated with learning deficits and synaptic undergrowth in Drosophila.

Willemsen MH, Nijhof B, Fenckova M, Nillesen WM, Bongers EM, Castells-Nobau A, Asztalos L, Viragh E, van Bon BW, Tezel E, Veltman JA, Brunner HG, de Vries BB, de Ligt J, Yntema HG, van Bokhoven H, Isidor B, Le Caignec C, Lorino E, Asztalos Z, Koolen DA, Vissers LE, Schenck A, Kleefstra T.

J Med Genet. 2013 Aug;50(8):507-14. doi: 10.1136/jmedgenet-2012-101490. Epub 2013 May 4.

PMID:
23644463
48.

CEP89 is required for mitochondrial metabolism and neuronal function in man and fly.

van Bon BW, Oortveld MA, Nijtmans LG, Fenckova M, Nijhof B, Besseling J, Vos M, Kramer JM, de Leeuw N, Castells-Nobau A, Asztalos L, Viragh E, Ruiter M, Hofmann F, Eshuis L, Collavin L, Huynen MA, Asztalos Z, Verstreken P, Rodenburg RJ, Smeitink JA, de Vries BB, Schenck A.

Hum Mol Genet. 2013 Aug 1;22(15):3138-51. doi: 10.1093/hmg/ddt170. Epub 2013 Apr 10.

PMID:
23575228
49.

Integrating palliative care information and hospice referral in medicaid primary care.

Beyea A, Fischer J, Schenck A, Hanson LC.

J Palliat Med. 2013 Apr;16(4):376-82. doi: 10.1089/jpm.2012.0483. Epub 2013 Mar 5.

PMID:
23461299
50.

Homozygous and heterozygous disruptions of ANK3: at the crossroads of neurodevelopmental and psychiatric disorders.

Iqbal Z, Vandeweyer G, van der Voet M, Waryah AM, Zahoor MY, Besseling JA, Roca LT, Vulto-van Silfhout AT, Nijhof B, Kramer JM, Van der Aa N, Ansar M, Peeters H, Helsmoortel C, Gilissen C, Vissers LE, Veltman JA, de Brouwer AP, Frank Kooy R, Riazuddin S, Schenck A, van Bokhoven H, Rooms L.

Hum Mol Genet. 2013 May 15;22(10):1960-70. doi: 10.1093/hmg/ddt043. Epub 2013 Feb 5.

PMID:
23390136

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