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Items: 1 to 50 of 200

1.

A Retrospective Study Using the String of Pearls Tibial Plateau Levelling Osteotomy Locking Plate for the Treatment of Cranial Cruciate Ligament Disease.

McGregor RE, Buffa EA, Tan CJ, Schembri MA, Badcock CA, Lai A.

Vet Comp Orthop Traumatol. 2019 Jun 21. doi: 10.1055/s-0039-1692189. [Epub ahead of print]

PMID:
31226722
2.

Physical Extraction and Fast Protein Liquid Chromatography for Purifying Flagella Filament From Uropathogenic Escherichia coli for Immune Assay.

Acharya D, Sullivan MJ, Duell BL, Eveno T, Schembri MA, Ulett GC.

Front Cell Infect Microbiol. 2019 Apr 24;9:118. doi: 10.3389/fcimb.2019.00118. eCollection 2019.

3.

Unique structural features of a bacterial autotransporter adhesin suggest mechanisms for interaction with host macromolecules.

Paxman JJ, Lo AW, Sullivan MJ, Panjikar S, Kuiper M, Whitten AE, Wang G, Luan CH, Moriel DG, Tan L, Peters KM, Phan MD, Gee CL, Ulett GC, Schembri MA, Heras B.

Nat Commun. 2019 Apr 29;10(1):1967. doi: 10.1038/s41467-019-09814-6.

4.

Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonization.

Murthy AMV, Sullivan MJ, Nhu NTK, Lo AW, Phan MD, Peters KM, Boucher D, Schroder K, Beatson SA, Ulett GC, Schembri MA, Sweet MJ.

FASEB J. 2019 Jun;33(6):7437-7450. doi: 10.1096/fj.201802100R. Epub 2019 Mar 14.

PMID:
30869997
5.

Uropathogenic Escherichia coli employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination.

Stocks CJ, Phan MD, Achard MES, Nhu NTK, Condon ND, Gawthorne JA, Lo AW, Peters KM, McEwan AG, Kapetanovic R, Schembri MA, Sweet MJ.

Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6341-6350. doi: 10.1073/pnas.1820870116. Epub 2019 Mar 7.

6.

Author Correction: A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance.

Furlong EJ, Lo AW, Kurth F, Premkumar L, Totsika M, Achard MES, Halili MA, Heras B, Whitten AE, Choudhury HG, Schembri MA, Martin JL.

Nat Commun. 2019 Mar 1;10(1):976. doi: 10.1038/s41467-019-08920-9.

7.

Chemical Synergy between Ionophore PBT2 and Zinc Reverses Antibiotic Resistance.

Bohlmann L, De Oliveira DMP, El-Deeb IM, Brazel EB, Harbison-Price N, Ong CY, Rivera-Hernandez T, Ferguson SA, Cork AJ, Phan MD, Soderholm AT, Davies MR, Nimmo GR, Dougan G, Schembri MA, Cook GM, McEwan AG, von Itzstein M, McDevitt CA, Walker MJ.

MBio. 2018 Dec 11;9(6). pii: e02391-18. doi: 10.1128/mBio.02391-18.

8.

Clay nanoparticles co-deliver three antigens to promote potent immune responses against pathogenic Escherichia coli.

Chen W, Zuo H, Rolfe B, Schembri MA, Cobbold RN, Zhang B, Mahony TJ, Xu ZP.

J Control Release. 2018 Dec 28;292:196-209. doi: 10.1016/j.jconrel.2018.11.008. Epub 2018 Nov 7.

PMID:
30414464
9.

Discovery of mcr-1-Mediated Colistin Resistance in a Highly Virulent Escherichia coli Lineage.

Forde BM, Zowawi HM, Harris PNA, Roberts L, Ibrahim E, Shaikh N, Deshmukh A, Sid Ahmed MA, Al Maslamani M, Cottrell K, Trembizki E, Sundac L, Yu HH, Li J, Schembri MA, Whiley DM, Paterson DL, Beatson SA.

mSphere. 2018 Oct 10;3(5). pii: e00486-18. doi: 10.1128/mSphere.00486-18.

10.

Discovery of New Genes Involved in Curli Production by a Uropathogenic Escherichia coli Strain from the Highly Virulent O45:K1:H7 Lineage.

Nhu NTK, Phan MD, Peters KM, Lo AW, Forde BM, Min Chong T, Yin WF, Chan KG, Chromek M, Brauner A, Chapman MR, Beatson SA, Schembri MA.

MBio. 2018 Aug 21;9(4). pii: e01462-18. doi: 10.1128/mBio.01462-18.

11.

Identification and Characterization of a Phase-Variable Element That Regulates the Autotransporter UpaE in Uropathogenic Escherichia coli.

Battaglioli EJ, Goh KGK, Atruktsang TS, Schwartz K, Schembri MA, Welch RA.

MBio. 2018 Aug 7;9(4). pii: e01360-18. doi: 10.1128/mBio.01360-18.

12.

The urinary microbiome in patients with refractory urge incontinence and recurrent urinary tract infection.

Chen Z, Phan MD, Bates LJ, Peters KM, Mukerjee C, Moore KH, Schembri MA.

Int Urogynecol J. 2018 Dec;29(12):1775-1782. doi: 10.1007/s00192-018-3679-2. Epub 2018 Jun 26.

13.

A Novel Method of Serum Resistance by Escherichia coli That Causes Urosepsis.

Coggon CF, Jiang A, Goh KGK, Henderson IR, Schembri MA, Wells TJ.

MBio. 2018 Jun 26;9(3). pii: e00920-18. doi: 10.1128/mBio.00920-18.

14.

Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages.

M V Murthy A, Phan MD, Peters KM, Nhu NTK, Welch RA, Ulett GC, Schembri MA, Sweet MJ.

Virulence. 2018 Dec 31;9(1):967-980. doi: 10.1080/21505594.2018.1465786.

15.

Molecular basis for the folding of β-helical autotransporter passenger domains.

Yuan X, Johnson MD, Zhang J, Lo AW, Schembri MA, Wijeyewickrema LC, Pike RN, Huysmans GHM, Henderson IR, Leyton DL.

Nat Commun. 2018 Apr 11;9(1):1395. doi: 10.1038/s41467-018-03593-2.

16.

Intestinal Colonization Traits of Pandemic Multidrug-Resistant Escherichia coli ST131.

Sarkar S, Hutton ML, Vagenas D, Ruter R, Schüller S, Lyras D, Schembri MA, Totsika M.

J Infect Dis. 2018 Aug 14;218(6):979-990. doi: 10.1093/infdis/jiy031.

17.

Bacterial pathogenesis and interleukin-17: interconnecting mechanisms of immune regulation, host genetics, and microbial virulence that influence severity of infection.

Chamoun MN, Blumenthal A, Sullivan MJ, Schembri MA, Ulett GC.

Crit Rev Microbiol. 2018 Aug;44(4):465-486. doi: 10.1080/1040841X.2018.1426556. Epub 2018 Jan 18. Review.

PMID:
29345518
18.

For when bacterial infections persist: Toll-like receptor-inducible direct antimicrobial pathways in macrophages.

Stocks CJ, Schembri MA, Sweet MJ, Kapetanovic R.

J Leukoc Biol. 2018 Jan;103(1):35-51. doi: 10.1002/JLB.4RI0917-358R. Epub 2018 Jan 3. Review.

PMID:
29345056
19.

Whole genome analysis of cephalosporin-resistant Escherichia coli from bloodstream infections in Australia, New Zealand and Singapore: high prevalence of CMY-2 producers and ST131 carrying blaCTX-M-15 and blaCTX-M-27.

Harris PNA, Ben Zakour NL, Roberts LW, Wailan AM, Zowawi HM, Tambyah PA, Lye DC, Jureen R, Lee TH, Yin M, Izharuddin E, Looke D, Runnegar N, Rogers B, Bhally H, Crowe A, Schembri MA, Beatson SA, Paterson DL; MERINO Trial investigators.

J Antimicrob Chemother. 2018 Mar 1;73(3):634-642. doi: 10.1093/jac/dkx466.

PMID:
29253152
20.

Copper Ions and Coordination Complexes as Novel Carbapenem Adjuvants.

Djoko KY, Achard MES, Phan MD, Lo AW, Miraula M, Prombhul S, Hancock SJ, Peters KM, Sidjabat HE, Harris PN, Mitić N, Walsh TR, Anderson GJ, Shafer WM, Paterson DL, Schenk G, McEwan AG, Schembri MA.

Antimicrob Agents Chemother. 2018 Jan 25;62(2). pii: e02280-17. doi: 10.1128/AAC.02280-17. Print 2018 Feb.

21.

Modifications in the pmrB gene are the primary mechanism for the development of chromosomally encoded resistance to polymyxins in uropathogenic Escherichia coli.

Phan MD, Nhu NTK, Achard MES, Forde BM, Hong KW, Chong TM, Yin WF, Chan KG, West NP, Walker MJ, Paterson DL, Beatson SA, Schembri MA.

J Antimicrob Chemother. 2017 Oct 1;72(10):2729-2736. doi: 10.1093/jac/dkx204.

PMID:
29091192
22.

Genome-Wide Discovery of Genes Required for Capsule Production by Uropathogenic Escherichia coli.

Goh KGK, Phan MD, Forde BM, Chong TM, Yin WF, Chan KG, Ulett GC, Sweet MJ, Beatson SA, Schembri MA.

MBio. 2017 Oct 24;8(5). pii: e01558-17. doi: 10.1128/mBio.01558-17.

23.

Crystal Structures of Staphylococcus aureus Ketol-Acid Reductoisomerase in Complex with Two Transition State Analogues that Have Biocidal Activity.

Patel KM, Teran D, Zheng S, Kandale A, Garcia M, Lv Y, Schembri MA, McGeary RP, Schenk G, Guddat LW.

Chemistry. 2017 Dec 22;23(72):18289-18295. doi: 10.1002/chem.201704481. Epub 2017 Nov 30.

PMID:
28975665
24.

YeeJ is an inverse autotransporter from Escherichia coli that binds to peptidoglycan and promotes biofilm formation.

Martinez-Gil M, Goh KGK, Rackaityte E, Sakamoto C, Audrain B, Moriel DG, Totsika M, Ghigo JM, Schembri MA, Beloin C.

Sci Rep. 2017 Sep 12;7(1):11326. doi: 10.1038/s41598-017-10902-0.

25.

A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance.

Furlong EJ, Lo AW, Kurth F, Premkumar L, Totsika M, Achard MES, Halili MA, Heras B, Whitten AE, Choudhury HG, Schembri MA, Martin JL.

Nat Commun. 2017 Jul 19;8:16065. doi: 10.1038/ncomms16065. Erratum in: Nat Commun. 2019 Mar 1;10(1):976.

26.

Structure-function analyses of a pertussis-like toxin from pathogenic Escherichia coli reveal a distinct mechanism of inhibition of trimeric G-proteins.

Littler DR, Ang SY, Moriel DG, Kocan M, Kleifeld O, Johnson MD, Tran MT, Paton AW, Paton JC, Summers RJ, Schembri MA, Rossjohn J, Beddoe T.

J Biol Chem. 2017 Sep 8;292(36):15143-15158. doi: 10.1074/jbc.M117.796094. Epub 2017 Jun 29.

27.

Interplay between tolerance mechanisms to copper and acid stress in Escherichia coli.

Djoko KY, Phan MD, Peters KM, Walker MJ, Schembri MA, McEwan AG.

Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):6818-6823. doi: 10.1073/pnas.1620232114. Epub 2017 Jun 13.

28.

'Omic' Approaches to Study Uropathogenic Escherichia coli Virulence.

Lo AW, Moriel DG, Phan MD, Schulz BL, Kidd TJ, Beatson SA, Schembri MA.

Trends Microbiol. 2017 Sep;25(9):729-740. doi: 10.1016/j.tim.2017.04.006. Epub 2017 May 24. Review.

PMID:
28550944
29.

Novel genes associated with enhanced motility of Escherichia coli ST131.

Kakkanat A, Phan MD, Lo AW, Beatson SA, Schembri MA.

PLoS One. 2017 May 10;12(5):e0176290. doi: 10.1371/journal.pone.0176290. eCollection 2017.

30.

Bacterial pathogenesis: Remodelling recurrent infection.

Ulett GC, Schembri MA.

Nat Microbiol. 2016 Dec 20;2:16256. doi: 10.1038/nmicrobiol.2016.256. No abstract available.

PMID:
27995931
31.

A Novel Protective Vaccine Antigen from the Core Escherichia coli Genome.

Moriel DG, Tan L, Goh KG, Phan MD, Ipe DS, Lo AW, Peters KM, Ulett GC, Beatson SA, Schembri MA.

mSphere. 2016 Nov 23;1(6). pii: e00326-16. eCollection 2016 Nov-Dec.

32.

Identification of IncA/C Plasmid Replication and Maintenance Genes and Development of a Plasmid Multilocus Sequence Typing Scheme.

Hancock SJ, Phan MD, Peters KM, Forde BM, Chong TM, Yin WF, Chan KG, Paterson DL, Walsh TR, Beatson SA, Schembri MA.

Antimicrob Agents Chemother. 2017 Jan 24;61(2). pii: e01740-16. doi: 10.1128/AAC.01740-16. Print 2017 Feb.

33.

The cytochrome bd-I respiratory oxidase augments survival of multidrug-resistant Escherichia coli during infection.

Shepherd M, Achard ME, Idris A, Totsika M, Phan MD, Peters KM, Sarkar S, Ribeiro CA, Holyoake LV, Ladakis D, Ulett GC, Sweet MJ, Poole RK, McEwan AG, Schembri MA.

Sci Rep. 2016 Oct 21;6:35285. doi: 10.1038/srep35285.

34.

Differential Regulation of the Surface-Exposed and Secreted SslE Lipoprotein in Extraintestinal Pathogenic Escherichia coli.

Tan L, Moriel DG, Totsika M, Beatson SA, Schembri MA.

PLoS One. 2016 Sep 6;11(9):e0162391. doi: 10.1371/journal.pone.0162391. eCollection 2016.

35.

Effective assembly of fimbriae in Escherichia coli depends on the translocation assembly module nanomachine.

Stubenrauch C, Belousoff MJ, Hay ID, Shen HH, Lillington J, Tuck KL, Peters KM, Phan MD, Lo AW, Schembri MA, Strugnell RA, Waksman G, Lithgow T.

Nat Microbiol. 2016 May 16;1(7):16064. doi: 10.1038/nmicrobiol.2016.64.

PMID:
27572967
36.

Detection of intracellular bacteria in exfoliated urothelial cells from women with urge incontinence.

Cheng Y, Chen Z, Gawthorne JA, Mukerjee C, Varettas K, Mansfield KJ, Schembri MA, Moore KH.

Pathog Dis. 2016 Oct;74(7). pii: ftw067. doi: 10.1093/femspd/ftw067. Epub 2016 Jul 7.

PMID:
27402784
37.

Erratum for Ben Zakour et al., Sequential Acquisition of Virulence and Fluoroquinolone Resistance Has Shaped the Evolution of Escherichia coli ST131.

Ben Zakour NL, Alsheikh-Hussain AS, Ashcroft MM, Khanh Nhu NT, Roberts LW, Stanton-Cook M, Schembri MA, Beatson SA.

MBio. 2016 Jun 28;7(3). pii: e00958-16. doi: 10.1128/mBio.00958-16. No abstract available.

38.

Comprehensive analysis of type 1 fimbriae regulation in fimB-null strains from the multidrug resistant Escherichia coli ST131 clone.

Sarkar S, Roberts LW, Phan MD, Tan L, Lo AW, Peters KM, Paterson DL, Upton M, Ulett GC, Beatson SA, Totsika M, Schembri MA.

Mol Microbiol. 2016 Sep;101(6):1069-87. doi: 10.1111/mmi.13442. Epub 2016 Jul 15.

39.

Sequential Acquisition of Virulence and Fluoroquinolone Resistance Has Shaped the Evolution of Escherichia coli ST131.

Ben Zakour NL, Alsheikh-Hussain AS, Ashcroft MM, Khanh Nhu NT, Roberts LW, Stanton-Cook M, Schembri MA, Beatson SA.

MBio. 2016 Apr 26;7(2):e00347-16. doi: 10.1128/mBio.00347-16. Erratum in: MBio. 2016 Jun 28;7(3):null.

40.

Mechanisms Involved in Acquisition of blaNDM Genes by IncA/C2 and IncFIIY Plasmids.

Wailan AM, Sidjabat HE, Yam WK, Alikhan NF, Petty NK, Sartor AL, Williamson DA, Forde BM, Schembri MA, Beatson SA, Paterson DL, Walsh TR, Partridge SR.

Antimicrob Agents Chemother. 2016 Jun 20;60(7):4082-8. doi: 10.1128/AAC.00368-16. Print 2016 Jul.

41.

Molecular and Structural Characterization of a Novel Escherichia coli Interleukin Receptor Mimic Protein.

Moriel DG, Heras B, Paxman JJ, Lo AW, Tan L, Sullivan MJ, Dando SJ, Beatson SA, Ulett GC, Schembri MA.

MBio. 2016 Mar 15;7(2):e02046. doi: 10.1128/mBio.02046-15.

42.

Biofilms 2015: Multidisciplinary Approaches Shed Light into Microbial Life on Surfaces.

Visick KL, Schembri MA, Yildiz F, Ghigo JM.

J Bacteriol. 2016 Sep 9;198(19):2553-63. doi: 10.1128/JB.00156-16. Print 2016 Oct 1. Review.

43.

Biofilm formation by multidrug resistant Escherichia coli ST131 is dependent on type 1 fimbriae and assay conditions.

Sarkar S, Vagenas D, Schembri MA, Totsika M.

Pathog Dis. 2016 Apr;74(3). pii: ftw013. doi: 10.1093/femspd/ftw013. Epub 2016 Mar 2.

PMID:
26940589
44.

Crystal structure of Mycobacterium tuberculosis ketol-acid reductoisomerase at 1.0 Å resolution - a potential target for anti-tuberculosis drug discovery.

Lv Y, Kandale A, Wun SJ, McGeary RP, Williams SJ, Kobe B, Sieber V, Schembri MA, Schenk G, Guddat LW.

FEBS J. 2016 Apr;283(7):1184-96. doi: 10.1111/febs.13672. Epub 2016 Feb 18.

45.

Molecular Characterization of the Vacuolating Autotransporter Toxin in Uropathogenic Escherichia coli.

Nichols KB, Totsika M, Moriel DG, Lo AW, Yang J, Wurpel DJ, Rossiter AE, Strugnell RA, Henderson IR, Ulett GC, Beatson SA, Schembri MA.

J Bacteriol. 2016 Apr 28;198(10):1487-98. doi: 10.1128/JB.00791-15. Print 2016 May 15.

46.

Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages.

Kapetanovic R, Bokil NJ, Achard ME, Ong CL, Peters KM, Stocks CJ, Phan MD, Monteleone M, Schroder K, Irvine KM, Saunders BM, Walker MJ, Stacey KJ, McEwan AG, Schembri MA, Sweet MJ.

FASEB J. 2016 May;30(5):1901-12. doi: 10.1096/fj.201500061. Epub 2016 Feb 2.

PMID:
26839376
47.

Co-transcriptomic Analysis by RNA Sequencing to Simultaneously Measure Regulated Gene Expression in Host and Bacterial Pathogen.

Ravasi T, Mavromatis CH, Bokil NJ, Schembri MA, Sweet MJ.

Methods Mol Biol. 2016;1390:145-58. doi: 10.1007/978-1-4939-3335-8_10.

PMID:
26803628
48.

Lineage-Specific Methyltransferases Define the Methylome of the Globally Disseminated Escherichia coli ST131 Clone.

Forde BM, Phan MD, Gawthorne JA, Ashcroft MM, Stanton-Cook M, Sarkar S, Peters KM, Chan KG, Chong TM, Yin WF, Upton M, Schembri MA, Beatson SA.

MBio. 2015 Nov 17;6(6):e01602-15. doi: 10.1128/mBio.01602-15.

49.

Discovery and Characterization of Human-Urine Utilization by Asymptomatic-Bacteriuria-Causing Streptococcus agalactiae.

Ipe DS, Ben Zakour NL, Sullivan MJ, Beatson SA, Ulett KB, Benjamin WH Jr, Davies MR, Dando SJ, King NP, Cripps AW, Schembri MA, Dougan G, Ulett GC.

Infect Immun. 2015 Nov 9;84(1):307-19. doi: 10.1128/IAI.00938-15. Print 2016 Jan.

50.

The role of H4 flagella in Escherichia coli ST131 virulence.

Kakkanat A, Totsika M, Schaale K, Duell BL, Lo AW, Phan MD, Moriel DG, Beatson SA, Sweet MJ, Ulett GC, Schembri MA.

Sci Rep. 2015 Nov 9;5:16149. doi: 10.1038/srep16149.

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