Sort by
Items per page

Send to

Choose Destination

Search results

Items: 6


The upstream conserved regions (UCRs) mediate homo- and hetero-oligomerization of type 4 cyclic nucleotide phosphodiesterases (PDE4s).

Xie M, Blackman B, Scheitrum C, Mika D, Blanchard E, Lei T, Conti M, Richter W.

Biochem J. 2014 May 1;459(3):539-50. doi: 10.1042/BJ20131681.


Anchored PDE4 regulates chloride conductance in wild-type and ΔF508-CFTR human airway epithelia.

Blanchard E, Zlock L, Lao A, Mika D, Namkung W, Xie M, Scheitrum C, Gruenert DC, Verkman AS, Finkbeiner WE, Conti M, Richter W.

FASEB J. 2014 Feb;28(2):791-801. doi: 10.1096/fj.13-240861. Epub 2013 Nov 7.


Cyclic adenosine monophosphate phosphodiesterase type 4 protects against atrial arrhythmias.

Molina CE, Leroy J, Richter W, Xie M, Scheitrum C, Lee IO, Maack C, Rucker-Martin C, Donzeau-Gouge P, Verde I, Llach A, Hove-Madsen L, Conti M, Vandecasteele G, Fischmeister R.

J Am Coll Cardiol. 2012 Jun 12;59(24):2182-90. doi: 10.1016/j.jacc.2012.01.060.


Phosphodiesterase 4B in the cardiac L-type Ca²⁺ channel complex regulates Ca²⁺ current and protects against ventricular arrhythmias in mice.

Leroy J, Richter W, Mika D, Castro LR, Abi-Gerges A, Xie M, Scheitrum C, Lefebvre F, Schittl J, Mateo P, Westenbroek R, Catterall WA, Charpentier F, Conti M, Fischmeister R, Vandecasteele G.

J Clin Invest. 2011 Jul;121(7):2651-61. doi: 10.1172/JCI44747. Epub 2011 Jun 13.


Inactivation of multidrug resistance proteins disrupts both cellular extrusion and intracellular degradation of cAMP.

Xie M, Rich TC, Scheitrum C, Conti M, Richter W.

Mol Pharmacol. 2011 Aug;80(2):281-93. doi: 10.1124/mol.111.071134. Epub 2011 May 6.


Conserved expression and functions of PDE4 in rodent and human heart.

Richter W, Xie M, Scheitrum C, Krall J, Movsesian MA, Conti M.

Basic Res Cardiol. 2011 Mar;106(2):249-62. doi: 10.1007/s00395-010-0138-8. Epub 2010 Dec 16.

Supplemental Content

Loading ...
Support Center