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Items: 1 to 50 of 163

1.

Single-subject analysis of N400 event-related potential component with five different methods.

Kallionpää RE, Pesonen H, Scheinin A, Sandman N, Laitio R, Scheinin H, Revonsuo A, Valli K.

Int J Psychophysiol. 2019 Oct;144:14-24. doi: 10.1016/j.ijpsycho.2019.06.012. Epub 2019 Jun 19.

2.

Alterations in heart rate variability in patients with peripheral arterial disease requiring surgical revascularization have limited association with postoperative major adverse cardiovascular and cerebrovascular events.

Utriainen KT, Airaksinen JK, Polo OJ, Scheinin H, Laitio RM, Leino KA, Vahlberg TJ, Kuusela TA, Laitio TT.

PLoS One. 2018 Sep 13;13(9):e0203519. doi: 10.1371/journal.pone.0203519. eCollection 2018.

3.

Comparative effects of dexmedetomidine, propofol, sevoflurane, and S-ketamine on regional cerebral glucose metabolism in humans: a positron emission tomography study.

Laaksonen L, Kallioinen M, Långsjö J, Laitio T, Scheinin A, Scheinin J, Kaisti K, Maksimow A, Kallionpää RE, Rajala V, Johansson J, Kantonen O, Nyman M, Sirén S, Valli K, Revonsuo A, Solin O, Vahlberg T, Alkire M, Scheinin H.

Br J Anaesth. 2018 Jul;121(1):281-290. doi: 10.1016/j.bja.2018.04.008. Epub 2018 May 8.

4.

Spoken words are processed during dexmedetomidine-induced unresponsiveness.

Kallionpää RE, Scheinin A, Kallionpää RA, Sandman N, Kallioinen M, Laitio R, Laitio T, Kaskinoro K, Kuusela T, Revonsuo A, Scheinin H, Valli K.

Br J Anaesth. 2018 Jul;121(1):270-280. doi: 10.1016/j.bja.2018.04.032. Epub 2018 May 23.

5.

Dreaming and awareness during dexmedetomidine- and propofol-induced unresponsiveness.

Radek L, Kallionpää RE, Karvonen M, Scheinin A, Maksimow A, Långsjö J, Kaisti K, Vahlberg T, Revonsuo A, Scheinin H, Valli K.

Br J Anaesth. 2018 Jul;121(1):260-269. doi: 10.1016/j.bja.2018.03.014. Epub 2018 May 10.

6.

Using Positron Emission Tomography in Revealing the Mystery of General Anesthesia: Study Design Challenges and Opportunities.

Scheinin H, Alkire EC, Scheinin A, Alkire MT, Kantonen O, Långsjö J.

Methods Enzymol. 2018;603:279-303. doi: 10.1016/bs.mie.2018.01.025. Epub 2018 Mar 9.

PMID:
29673531
7.

Differentiating Drug-related and State-related Effects of Dexmedetomidine and Propofol on the Electroencephalogram.

Scheinin A, Kallionpää RE, Li D, Kallioinen M, Kaisti K, Långsjö J, Maksimow A, Vahlberg T, Valli K, Mashour GA, Revonsuo A, Scheinin H.

Anesthesiology. 2018 Jul;129(1):22-36. doi: 10.1097/ALN.0000000000002192.

PMID:
29642080
8.

Inhaled Xenon Attenuates Myocardial Damage in Comatose Survivors of Out-of-Hospital Cardiac Arrest: The Xe-Hypotheca Trial.

Arola O, Saraste A, Laitio R, Airaksinen J, Hynninen M, Bäcklund M, Ylikoski E, Wennervirta J, Pietilä M, Roine RO, Harjola VP, Niiranen J, Korpi K, Varpula M, Scheinin H, Maze M, Vahlberg T, Laitio T; Xe-HYPOTHECA Study Group.

J Am Coll Cardiol. 2017 Nov 28;70(21):2652-2660. doi: 10.1016/j.jacc.2017.09.1088.

9.

Effect of Inhaled Xenon on Cerebral White Matter Damage in Comatose Survivors of Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial.

Laitio R, Hynninen M, Arola O, Virtanen S, Parkkola R, Saunavaara J, Roine RO, Grönlund J, Ylikoski E, Wennervirta J, Bäcklund M, Silvasti P, Nukarinen E, Tiainen M, Saraste A, Pietilä M, Airaksinen J, Valanne L, Martola J, Silvennoinen H, Scheinin H, Harjola VP, Niiranen J, Korpi K, Varpula M, Inkinen O, Olkkola KT, Maze M, Vahlberg T, Laitio T.

JAMA. 2016 Mar 15;315(11):1120-8. doi: 10.1001/jama.2016.1933.

10.

[Is it possible to measure the depth of anesthesia using electroencephalogram?].

Yli-Hankala A, Scheinin H.

Duodecim. 2015;131(20):1929-36. Review. Finnish.

PMID:
26638347
11.

Detecting a dexmedetomidine-evoked reduction of noradrenaline release in the human brain with the alpha2C-adrenoceptor PET ligand [11C]ORM-13070.

Lehto J, Scheinin A, Johansson J, Marjamäki P, Arponen E, Scheinin H, Scheinin M.

Synapse. 2016 Feb;70(2):57-65. doi: 10.1002/syn.21872. Epub 2015 Nov 26.

PMID:
26562363
12.

Sensitivity of [(11)C]ORM-13070 to increased extracellular noradrenaline in the CNS - a PET study in human subjects.

Lehto J, Johansson J, Vuorilehto L, Luoto P, Arponen E, Scheinin H, Rouru J, Scheinin M.

Psychopharmacology (Berl). 2015 Nov;232(21-22):4169-78. doi: 10.1007/s00213-015-3941-y. Epub 2015 Apr 29.

PMID:
25918111
13.

Imaging of α2C-adrenoceptors in the living brain: a method to monitor noradrenaline release?

Scheinin M, Lehto J, Johansson J, Luoto P, Arponen E, Vuorilehto L, Scheinin H, Rouru J.

Springerplus. 2015 Jun 12;4(Suppl 1):L20. doi: 10.1186/2193-1801-4-S1-L20. eCollection 2015. No abstract available.

14.

White matter damage of the brain is associated with poor outcome in vascular surgery patients with claudication: a pilot study.

Virtanen S, Utriainen KT, Parkkola R, Airaksinen JK, Laitio R, Scheinin H, Hakovirta H, Laitio TT; BAROSLEEP Study Group.

Eur J Vasc Endovasc Surg. 2014 Dec;48(6):687-93. doi: 10.1016/j.ejvs.2014.08.025. Epub 2014 Oct 1.

15.

Validation of [(11) C]ORM-13070 as a PET tracer for alpha2c -adrenoceptors in the human brain.

Lehto J, Hirvonen MM, Johansson J, Kemppainen J, Luoto P, Naukkarinen T, Oikonen V, Arponen E, Rouru J, Sallinen J, Scheinin H, Vuorilehto L, Finnema SJ, Halldin C, Rinne JO, Scheinin M.

Synapse. 2015 Mar;69(3):172-81. doi: 10.1002/syn.21798. Epub 2015 Jan 8.

PMID:
25530024
16.

Intravenous ethanol increases dopamine release in the ventral striatum in humans: PET study using bolus-plus-infusion administration of [(11)C]raclopride.

Aalto S, Ingman K, Alakurtti K, Kaasinen V, Virkkala J, Någren K, Rinne JO, Scheinin H.

J Cereb Blood Flow Metab. 2015 Mar;35(3):424-31. doi: 10.1038/jcbfm.2014.209. Epub 2014 Dec 10.

17.

Directional connectivity between frontal and posterior brain regions is altered with increasing concentrations of propofol.

Maksimow A, Silfverhuth M, Långsjö J, Kaskinoro K, Georgiadis S, Jääskeläinen S, Scheinin H.

PLoS One. 2014 Nov 24;9(11):e113616. doi: 10.1371/journal.pone.0113616. eCollection 2014.

18.

Electroencephalogram reactivity to verbal command after dexmedetomidine, propofol and sevoflurane-induced unresponsiveness.

Kaskinoro K, Maksimow A, Georgiadis S, Långsjö J, Scheinin H, Karjalainen P, Jääskeläinen SK.

Anaesthesia. 2015 Feb;70(2):190-204. doi: 10.1111/anae.12868. Epub 2014 Sep 29.

19.

Sleep apnoea is associated with major cardiac events in peripheral arterial disease.

Utriainen KT, Airaksinen JK, Polo O, Laitio R, Pietilä MJ, Scheinin H, Vahlberg T, Leino KA, Kentala ES, Jalonen JR, Hakovirta H, Parkkola R, Virtanen S, Laitio TT.

Eur Respir J. 2014 Jun;43(6):1652-60. doi: 10.1183/09031936.00130913. Epub 2014 Feb 20.

20.

Harnessing anesthesia and brain imaging for the study of human consciousness.

Långsjo JW, Revonsuo A, Scheinin H.

Curr Pharm Des. 2014;20(26):4211-24. Review.

PMID:
24025060
21.

Feasibility and cardiac safety of inhaled xenon in combination with therapeutic hypothermia following out-of-hospital cardiac arrest.

Arola OJ, Laitio RM, Roine RO, Grönlund J, Saraste A, Pietilä M, Airaksinen J, Perttilä J, Scheinin H, Olkkola KT, Maze M, Laitio TT.

Crit Care Med. 2013 Sep;41(9):2116-24. doi: 10.1097/CCM.0b013e31828a4337.

PMID:
23896830
22.

Why does bispectral index monitoring not perform better?

Scheinin H, Långsjö JW.

Anesthesiology. 2013 May;118(5):1233-4. doi: 10.1097/ALN.0b013e318289b936. No abstract available.

PMID:
23612134
23.

Unrecognised obstructive sleep apnoea is common in severe peripheral arterial disease.

Utriainen KT, Airaksinen JK, Polo O, Raitakari OT, Pietilä MJ, Scheinin H, Helenius HY, Leino KA, Kentala ES, Jalonen JR, Hakovirta H, Salo TM, Laitio TT.

Eur Respir J. 2013 Mar;41(3):616-20. doi: 10.1183/09031936.00227611. Epub 2012 Jun 14.

24.

Striatal μ-opioid receptor availability predicts cold pressor pain threshold in healthy human subjects.

Hagelberg N, Aalto S, Tuominen L, Pesonen U, Någren K, Hietala J, Scheinin H, Pertovaara A, Martikainen IK.

Neurosci Lett. 2012 Jul 11;521(1):11-4. doi: 10.1016/j.neulet.2012.05.042. Epub 2012 May 20.

PMID:
22622175
25.

Returning from oblivion: imaging the neural core of consciousness.

Långsjö JW, Alkire MT, Kaskinoro K, Hayama H, Maksimow A, Kaisti KK, Aalto S, Aantaa R, Jääskeläinen SK, Revonsuo A, Scheinin H.

J Neurosci. 2012 Apr 4;32(14):4935-43. doi: 10.1523/JNEUROSCI.4962-11.2012.

26.

Heart rate variability dynamics during low-dose propofol and dexmedetomidine anesthesia.

Tarvainen MP, Georgiadis S, Laitio T, Lipponen JA, Karjalainen PA, Kaskinoro K, Scheinin H.

Ann Biomed Eng. 2012 Aug;40(8):1802-13. doi: 10.1007/s10439-012-0544-1. Epub 2012 Mar 15.

PMID:
22419196
27.

Consciousness lost and found: subjective experiences in an unresponsive state.

Noreika V, Jylhänkangas L, Móró L, Valli K, Kaskinoro K, Aantaa R, Scheinin H, Revonsuo A.

Brain Cogn. 2011 Dec;77(3):327-34. doi: 10.1016/j.bandc.2011.09.002. Epub 2011 Oct 8.

PMID:
21986366
28.

Wide inter-individual variability of bispectral index and spectral entropy at loss of consciousness during increasing concentrations of dexmedetomidine, propofol, and sevoflurane.

Kaskinoro K, Maksimow A, Långsjö J, Aantaa R, Jääskeläinen S, Kaisti K, Särkelä M, Scheinin H.

Br J Anaesth. 2011 Oct;107(4):573-80. doi: 10.1093/bja/aer196. Epub 2011 Jul 6.

29.

Renal effects of dexmedetomidine during coronary artery bypass surgery: a randomized placebo-controlled study.

Leino K, Hynynen M, Jalonen J, Salmenperä M, Scheinin H, Aantaa R; Dexmedetomidine in Cardiac Surgery Study Group.

BMC Anesthesiol. 2011 May 23;11:9. doi: 10.1186/1471-2253-11-9.

30.

Delta entropy of heart rate variability along with deepening anesthesia.

Mäenpää M, Laitio T, Kuusela T, Penttilä J, Kaisti K, Aalto S, Hinkka-Yli-Salomäki S, Scheinin H.

Anesth Analg. 2011 Mar;112(3):587-92. doi: 10.1213/ANE.0b013e318208074d. Epub 2011 Jan 13.

PMID:
21233497
31.

Analysis of heart rate variability dynamics during propofol and dexmedetomidine anesthesia.

Tarvainen MP, Georgiadis S, Lipponen JA, Laitio T, Karjalainen PA, Scheinin H, Kaskinoro K.

Conf Proc IEEE Eng Med Biol Soc. 2010;2010:1634-7. doi: 10.1109/IEMBS.2010.5626878.

PMID:
21096389
32.

Kalman smoother based time-varying spectrum estimation of EEG during single agent propofol anesthesia.

Georgiadis SD, Tarvainen MP, Kaskinoro K, Maksimow A, Kärki T, Jääskeläinen S, Scheinin H, Karjalainen PA.

Conf Proc IEEE Eng Med Biol Soc. 2009;2009:5709-12. doi: 10.1109/IEMBS.2009.5332660.

PMID:
19963912
33.

C957T polymorphism of the human dopamine D2 receptor gene predicts extrastriatal dopamine receptor availability in vivo.

Hirvonen MM, Lumme V, Hirvonen J, Pesonen U, Någren K, Vahlberg T, Scheinin H, Hietala J.

Prog Neuropsychopharmacol Biol Psychiatry. 2009 Jun 15;33(4):630-6. doi: 10.1016/j.pnpbp.2009.02.021. Epub 2009 Mar 11.

PMID:
19285111
34.

The effects of xenon anesthesia on the relationship between cerebral glucose metabolism and blood flow in healthy subjects: a positron emission tomography study.

Laitio RM, Långsjö JW, Aalto S, Kaisti KK, Salmi E, Maksimow A, Aantaa R, Oikonen V, Viljanen T, Parkkola R, Scheinin H.

Anesth Analg. 2009 Feb;108(2):593-600. doi: 10.1213/ane.0b013e31818ffc9d.

PMID:
19151294
35.

The effects of d-amphetamine on extrastriatal dopamine D2/D3 receptors: a randomized, double-blind, placebo-controlled PET study with [11C]FLB 457 in healthy subjects.

Aalto S, Hirvonen J, Kaasinen V, Hagelberg N, Kajander J, Någren K, Seppälä T, Rinne JO, Scheinin H, Hietala J.

Eur J Nucl Med Mol Imaging. 2009 Mar;36(3):475-83. doi: 10.1007/s00259-008-0969-9. Epub 2008 Nov 5.

PMID:
18985345
36.

Measurement of central mu-opioid receptor binding in vivo with PET and [11C]carfentanil: a test-retest study in healthy subjects.

Hirvonen J, Aalto S, Hagelberg N, Maksimow A, Ingman K, Oikonen V, Virkkala J, Någren K, Scheinin H.

Eur J Nucl Med Mol Imaging. 2009 Feb;36(2):275-86. doi: 10.1007/s00259-008-0935-6. Epub 2008 Sep 9.

PMID:
18779961
37.

Measurement of GABAA receptor binding in vivo with [11C]flumazenil: a test-retest study in healthy subjects.

Salmi E, Aalto S, Hirvonen J, Långsjö JW, Maksimow AT, Oikonen V, Metsähonkala L, Virkkala J, Någren K, Scheinin H.

Neuroimage. 2008 Jun;41(2):260-9. doi: 10.1016/j.neuroimage.2008.02.035. Epub 2008 Mar 4.

PMID:
18411060
38.

Xenon does not affect gamma-aminobutyric acid type A receptor binding in humans.

Salmi E, Laitio RM, Aalto S, Maksimow AT, Långsjö JW, Kaisti KK, Aantaa R, Oikonen V, Metsähonkala L, Någren K, Korpi ER, Scheinin H.

Anesth Analg. 2008 Jan;106(1):129-34, table of contents. doi: 10.1213/01.ane.0000287658.14763.13.

PMID:
18165567
39.

Bispectral index, entropy, and quantitative electroencephalogram during single-agent xenon anesthesia.

Laitio RM, Kaskinoro K, Särkelä MO, Kaisti KK, Salmi E, Maksimow A, Långsjö JW, Aantaa R, Kangas K, Jääskeläinen S, Scheinin H.

Anesthesiology. 2008 Jan;108(1):63-70.

PMID:
18156883
40.

The role of heart rate variability in risk stratification for adverse postoperative cardiac events.

Laitio T, Jalonen J, Kuusela T, Scheinin H.

Anesth Analg. 2007 Dec;105(6):1548-60. Review.

PMID:
18042846
41.

Electroencephalogram spindle activity during dexmedetomidine sedation and physiological sleep.

Huupponen E, Maksimow A, Lapinlampi P, Särkelä M, Saastamoinen A, Snapir A, Scheinin H, Scheinin M, Meriläinen P, Himanen SL, Jääskeläinen S.

Acta Anaesthesiol Scand. 2008 Feb;52(2):289-94. Epub 2007 Nov 14.

PMID:
18005372
42.

Effect of 3 g of intravenous paracetamol on post-operative analgesia, platelet function and liver enzymes in patients undergoing tonsillectomy under local anaesthesia.

Silvanto M, Munsterhjelm E, Savolainen S, Tiainen P, Niemi T, Ylikorkala O, Scheinin H, Olkkola KT.

Acta Anaesthesiol Scand. 2007 Oct;51(9):1147-54. Epub 2007 Aug 15.

PMID:
17711562
43.

Effects of xenon anesthesia on cerebral blood flow in humans: a positron emission tomography study.

Laitio RM, Kaisti KK, Låangsjö JW, Aalto S, Salmi E, Maksimow A, Aantaa R, Oikonen V, Sipilä H, Parkkola R, Scheinin H.

Anesthesiology. 2007 Jun;106(6):1128-33.

PMID:
17525587
44.

The effects of surgical levels of sevoflurane and propofol anaesthesia on heart rate variability.

Mäenpää M, Penttilä J, Laitio T, Kaisti K, Kuusela T, Hinkka S, Scheinin H.

Eur J Anaesthesiol. 2007 Jul;24(7):626-33. Epub 2007 Mar 12.

PMID:
17376251
45.

Assessing the depth of dexmedetomidine-induced sedation with electroencephalogram (EEG)-based spectral entropy.

Maksimow A, Snapir A, Särkelä M, Kentala E, Koskenvuo J, Posti J, Jääskeläinen SK, Hinkka-Yli-Salomäki S, Scheinin M, Scheinin H.

Acta Anaesthesiol Scand. 2007 Jan;51(1):22-30. Epub 2006 Nov 1.

PMID:
17073855
46.

Effects of low and high plasma concentrations of dexmedetomidine on myocardial perfusion and cardiac function in healthy male subjects.

Snapir A, Posti J, Kentala E, Koskenvuo J, Sundell J, Tuunanen H, Hakala K, Scheinin H, Knuuti J, Scheinin M.

Anesthesiology. 2006 Nov;105(5):902-10; quiz 1069-70.

PMID:
17065883
47.

Increase in high frequency EEG activity explains the poor performance of EEG spectral entropy monitor during S-ketamine anesthesia.

Maksimow A, Särkelä M, Långsjö JW, Salmi E, Kaisti KK, Yli-Hankala A, Hinkka-Yli-Salomäki S, Scheinin H, Jääskeläinen SK.

Clin Neurophysiol. 2006 Aug;117(8):1660-8. Epub 2006 Jun 27.

PMID:
16807101
48.

Estimation of cardiac output in a pharmacological trial using a simple method based on arterial blood pressure signal waveform: a comparison with pulmonary thermodilution and echocardiographic methods.

Penttilä J, Snapir A, Kentala E, Koskenvuo J, Posti J, Scheinin M, Scheinin H, Kuusela T.

Eur J Clin Pharmacol. 2006 Jun;62(6):401-7. Epub 2006 Mar 29.

PMID:
16570186
49.

Long-term alterations of heart rate dynamics after coronary artery bypass graft surgery.

Laitio TT, Huikuri HV, Koskenvuo J, Jalonen J, Mäkikallio TH, Helenius H, Kentala ES, Hartiala J, Scheinin H.

Anesth Analg. 2006 Apr;102(4):1026-31.

PMID:
16551892
50.

Sub-anaesthestic doses of ketamine impair cardiac parasympathetic regulation.

Penttilä J, Maenpaa M, Laitio T, Långsjö J, Hinkka S, Scheinin H.

Eur J Anaesthesiol. 2005 Oct;22(10):808-10. No abstract available.

PMID:
16211790

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