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Items: 1 to 50 of 82

1.

Landscape of ribosome-engaged transcript isoforms reveals extensive neuronal-cell-class-specific alternative splicing programs.

Furlanis E, Traunmüller L, Fucile G, Scheiffele P.

Nat Neurosci. 2019 Aug 26. doi: 10.1038/s41593-019-0465-5. [Epub ahead of print]

PMID:
31451803
2.

Architects of neuronal wiring.

Falkner S, Scheiffele P.

Science. 2019 May 3;364(6439):437-438. doi: 10.1126/science.aax3221. No abstract available.

PMID:
31048478
3.

The Yin and Yang of Arnt2 in Activity-Dependent Transcription.

Okur Z, Scheiffele P.

Neuron. 2019 Apr 17;102(2):270-272. doi: 10.1016/j.neuron.2019.04.006.

PMID:
30998895
4.

Elfn1-Induced Constitutive Activation of mGluR7 Determines Frequency-Dependent Recruitment of Somatostatin Interneurons.

Stachniak TJ, Sylwestrak EL, Scheiffele P, Hall BJ, Ghosh A.

J Neurosci. 2019 Jun 5;39(23):4461-4474. doi: 10.1523/JNEUROSCI.2276-18.2019. Epub 2019 Apr 2.

PMID:
30940718
5.

A Sam68-dependent alternative splicing program shapes postsynaptic protein complexes.

Witte H, Schreiner D, Scheiffele P.

Eur J Neurosci. 2019 Jun;49(11):1436-1453. doi: 10.1111/ejn.14332. Epub 2019 Jan 29.

PMID:
30589479
6.

Role of VTA dopamine neurons and neuroligin 3 in sociability traits related to nonfamiliar conspecific interaction.

Bariselli S, Hörnberg H, Prévost-Solié C, Musardo S, Hatstatt-Burklé L, Scheiffele P, Bellone C.

Nat Commun. 2018 Aug 9;9(1):3173. doi: 10.1038/s41467-018-05382-3.

7.

Regulation of striatal cells and goal-directed behavior by cerebellar outputs.

Xiao L, Bornmann C, Hatstatt-Burklé L, Scheiffele P.

Nat Commun. 2018 Aug 7;9(1):3133. doi: 10.1038/s41467-018-05565-y.

8.

Regulation of Neuronal Differentiation, Function, and Plasticity by Alternative Splicing.

Furlanis E, Scheiffele P.

Annu Rev Cell Dev Biol. 2018 Oct 6;34:451-469. doi: 10.1146/annurev-cellbio-100617-062826. Epub 2018 Jul 20. Review.

9.

Local and long-range circuit elements for cerebellar function.

Xiao L, Scheiffele P.

Curr Opin Neurobiol. 2018 Feb;48:146-152. doi: 10.1016/j.conb.2017.12.016. Epub 2018 Jan 6. Review.

PMID:
29316490
10.

Cellular Functions of the Autism Risk Factor PTCHD1 in Mice.

Tora D, Gomez AM, Michaud JF, Yam PT, Charron F, Scheiffele P.

J Neurosci. 2017 Dec 6;37(49):11993-12005. doi: 10.1523/JNEUROSCI.1393-17.2017. Epub 2017 Nov 8.

11.

Beyond proteome diversity: alternative splicing as a regulator of neuronal transcript dynamics.

Mauger O, Scheiffele P.

Curr Opin Neurobiol. 2017 Aug;45:162-168. doi: 10.1016/j.conb.2017.05.012. Epub 2017 Jun 10. Review.

12.

Correction: An alternative splicing switch shapes neurexin repertoires in principal neurons versus interneurons in the mouse hippocampus.

Nguyen TM, Schreiner D, Xiao L, Traunmüller L, Bornmann C, Scheiffele P.

Elife. 2017 Apr 25;6. pii: e28013. doi: 10.7554/eLife.28013. No abstract available.

13.

Targeted Intron Retention and Excision for Rapid Gene Regulation in Response to Neuronal Activity.

Mauger O, Lemoine F, Scheiffele P.

Neuron. 2016 Dec 21;92(6):1266-1278. doi: 10.1016/j.neuron.2016.11.032.

14.

An alternative splicing switch shapes neurexin repertoires in principal neurons versus interneurons in the mouse hippocampus.

Nguyen TM, Schreiner D, Xiao L, Traunmüller L, Bornmann C, Scheiffele P.

Elife. 2016 Dec 13;5. pii: e22757. doi: 10.7554/eLife.22757. Erratum in: Elife. 2017 Apr 25;6:.

15.

Distinct Defects in Synaptic Differentiation of Neocortical Neurons in Response to Prenatal Valproate Exposure.

Iijima Y, Behr K, Iijima T, Biemans B, Bischofberger J, Scheiffele P.

Sci Rep. 2016 Jun 6;6:27400. doi: 10.1038/srep27400.

16.

Synaptic Ménage à Trois.

Furlanis E, Scheiffele P.

Neuron. 2016 May 18;90(4):665-7. doi: 10.1016/j.neuron.2016.05.007. Review.

17.

Control of neuronal synapse specification by a highly dedicated alternative splicing program.

Traunmüller L, Gomez AM, Nguyen TM, Scheiffele P.

Science. 2016 May 20;352(6288):982-6. doi: 10.1126/science.aaf2397. Epub 2016 May 12.

18.

Astrocytes Assemble Thalamocortical Synapses by Bridging NRX1α and NL1 via Hevin.

Singh SK, Stogsdill JA, Pulimood NS, Dingsdale H, Kim YH, Pilaz LJ, Kim IH, Manhaes AC, Rodrigues WS Jr, Pamukcu A, Enustun E, Ertuz Z, Scheiffele P, Soderling SH, Silver DL, Ji RR, Medina AE, Eroglu C.

Cell. 2016 Jan 14;164(1-2):183-196. doi: 10.1016/j.cell.2015.11.034.

19.

Presynaptic spinophilin tunes neurexin signalling to control active zone architecture and function.

Muhammad K, Reddy-Alla S, Driller JH, Schreiner D, Rey U, Böhme MA, Hollmann C, Ramesh N, Depner H, Lützkendorf J, Matkovic T, Götz T, Bergeron DD, Schmoranzer J, Goettfert F, Holt M, Wahl MC, Hell SW, Scheiffele P, Walter AM, Loll B, Sigrist SJ.

Nat Commun. 2015 Oct 16;6:8362. doi: 10.1038/ncomms9362.

20.

Quantitative isoform-profiling of highly diversified recognition molecules.

Schreiner D, Simicevic J, Ahrné E, Schmidt A, Scheiffele P.

Elife. 2015 May 18;4:e07794. doi: 10.7554/eLife.07794.

21.

Potent degradation of neuronal miRNAs induced by highly complementary targets.

de la Mata M, Gaidatzis D, Vitanescu M, Stadler MB, Wentzel C, Scheiffele P, Filipowicz W, Großhans H.

EMBO Rep. 2015 Apr;16(4):500-11. doi: 10.15252/embr.201540078. Epub 2015 Feb 27.

22.

Alternative splicing coupled nonsense-mediated decay generates neuronal cell type-specific expression of SLM proteins.

Traunmüller L, Bornmann C, Scheiffele P.

J Neurosci. 2014 Dec 10;34(50):16755-61. doi: 10.1523/JNEUROSCI.3395-14.2014.

23.

Targeted combinatorial alternative splicing generates brain region-specific repertoires of neurexins.

Schreiner D, Nguyen TM, Russo G, Heber S, Patrignani A, Ahrné E, Scheiffele P.

Neuron. 2014 Oct 22;84(2):386-98. doi: 10.1016/j.neuron.2014.09.011. Epub 2014 Oct 2.

24.

Polymorphic receptors: neuronal functions and molecular mechanisms of diversification.

Schreiner D, Nguyen TM, Scheiffele P.

Curr Opin Neurobiol. 2014 Aug;27:25-30. doi: 10.1016/j.conb.2014.02.009. Epub 2014 Mar 6. Review.

PMID:
24608163
25.

Neuronal cell type-specific alternative splicing is regulated by the KH domain protein SLM1.

Iijima T, Iijima Y, Witte H, Scheiffele P.

J Cell Biol. 2014 Feb 3;204(3):331-42. doi: 10.1083/jcb.201310136. Epub 2014 Jan 27.

26.

Neurobiology of autism gene products: towards pathogenesis and drug targets.

Kleijer KT, Schmeisser MJ, Krueger DD, Boeckers TM, Scheiffele P, Bourgeron T, Brose N, Burbach JP.

Psychopharmacology (Berl). 2014 Mar;231(6):1037-62. doi: 10.1007/s00213-013-3403-3. Epub 2014 Jan 14. Review.

PMID:
24419271
27.

Neuroscience: Sculpting neuronal connectivity.

Sylwestrak E, Scheiffele P.

Nature. 2013 Nov 7;503(7474):42-3. doi: 10.1038/503042a. No abstract available.

PMID:
24201274
28.

What, where, and when: the importance of post-transcriptional regulation in the brain.

Kiebler MA, Scheiffele P, Ule J.

Front Neurosci. 2013 Oct 29;7:192. doi: 10.3389/fnins.2013.00192. eCollection 2013. No abstract available.

29.

mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking.

Wentzel C, Sommer JE, Nair R, Stiefvater A, Sibarita JB, Scheiffele P.

Neuron. 2013 Jun 19;78(6):1012-23. doi: 10.1016/j.neuron.2013.05.010.

30.

Preparing for your future as you grow.

Scheiffele P.

Neuron. 2013 Jun 5;78(5):751-2. doi: 10.1016/j.neuron.2013.05.031.

31.

Total synthesis of gelsemiol.

Burch P, Binaghi M, Scherer M, Wentzel C, Bossert D, Eberhardt L, Neuburger M, Scheiffele P, Gademann K.

Chemistry. 2013 Feb 18;19(8):2589-91. doi: 10.1002/chem.201203746. Epub 2013 Jan 10. No abstract available.

PMID:
23307641
32.

Neuroligin-1 controls synaptic abundance of NMDA-type glutamate receptors through extracellular coupling.

Budreck EC, Kwon OB, Jung JH, Baudouin S, Thommen A, Kim HS, Fukazawa Y, Harada H, Tabuchi K, Shigemoto R, Scheiffele P, Kim JH.

Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):725-30. doi: 10.1073/pnas.1214718110. Epub 2012 Dec 26.

33.

Growth cone MKK7 mRNA targeting regulates MAP1b-dependent microtubule bundling to control neurite elongation.

Feltrin D, Fusco L, Witte H, Moretti F, Martin K, Letzelter M, Fluri E, Scheiffele P, Pertz O.

PLoS Biol. 2012;10(12):e1001439. doi: 10.1371/journal.pbio.1001439. Epub 2012 Dec 4.

34.

Choreographing the axo-dendritic dance.

Scheiffele P, Iijima T.

Dev Cell. 2012 Nov 13;23(5):923-4. doi: 10.1016/j.devcel.2012.10.020.

35.

Shared synaptic pathophysiology in syndromic and nonsyndromic rodent models of autism.

Baudouin SJ, Gaudias J, Gerharz S, Hatstatt L, Zhou K, Punnakkal P, Tanaka KF, Spooren W, Hen R, De Zeeuw CI, Vogt K, Scheiffele P.

Science. 2012 Oct 5;338(6103):128-32. doi: 10.1126/science.1224159. Epub 2012 Sep 13.

36.

SAM68 regulates neuronal activity-dependent alternative splicing of neurexin-1.

Iijima T, Wu K, Witte H, Hanno-Iijima Y, Glatter T, Richard S, Scheiffele P.

Cell. 2011 Dec 23;147(7):1601-14. doi: 10.1016/j.cell.2011.11.028.

37.

Distinct mechanisms regulate GABAA receptor and gephyrin clustering at perisomatic and axo-axonic synapses on CA1 pyramidal cells.

Panzanelli P, Gunn BG, Schlatter MC, Benke D, Tyagarajan SK, Scheiffele P, Belelli D, Lambert JJ, Rudolph U, Fritschy JM.

J Physiol. 2011 Oct 15;589(Pt 20):4959-80. doi: 10.1113/jphysiol.2011.216028. Epub 2011 Aug 8.

38.

Development of axon-target specificity of ponto-cerebellar afferents.

Kalinovsky A, Boukhtouche F, Blazeski R, Bornmann C, Suzuki N, Mason CA, Scheiffele P.

PLoS Biol. 2011 Feb 8;9(2):e1001013. doi: 10.1371/journal.pbio.1001013.

39.

Neuroscience: Angelman syndrome connections.

Scheiffele P, Beg AA.

Nature. 2010 Dec 16;468(7326):907-8. doi: 10.1038/468907a. No abstract available.

PMID:
21164477
40.

Cortical control of adaptive locomotion in wild-type mice and mutant mice lacking the ephrin-Eph effector protein alpha2-chimaerin.

Asante CO, Chu A, Fisher M, Benson L, Beg A, Scheiffele P, Martin J.

J Neurophysiol. 2010 Dec;104(6):3189-202. doi: 10.1152/jn.00671.2010. Epub 2010 Sep 29.

41.

Recent excitements about excitatory synapses.

Scheiffele P, Yuzaki M.

Eur J Neurosci. 2010 Jul;32(2):179-80. doi: 10.1111/j.1460-9568.2010.07360.x. Epub 2010 Jul 14. No abstract available.

PMID:
20646054
42.

SnapShot: Neuroligin-neurexin complexes.

Baudouin S, Scheiffele P.

Cell. 2010 May 28;141(5):908, 908.e1. doi: 10.1016/j.cell.2010.05.024. No abstract available.

43.

Genetics and cell biology of building specific synaptic connectivity.

Shen K, Scheiffele P.

Annu Rev Neurosci. 2010;33:473-507. doi: 10.1146/annurev.neuro.051508.135302. Review.

44.

Flexible Accelerated STOP Tetracycline Operator-knockin (FAST): a versatile and efficient new gene modulating system.

Tanaka KF, Ahmari SE, Leonardo ED, Richardson-Jones JW, Budreck EC, Scheiffele P, Sugio S, Inamura N, Ikenaka K, Hen R.

Biol Psychiatry. 2010 Apr 15;67(8):770-3. doi: 10.1016/j.biopsych.2009.12.020. Epub 2010 Feb 16.

45.

Imaging synaptogenesis by measuring accumulation of synaptic proteins.

Dean C, Scheiffele P.

Cold Spring Harb Protoc. 2009 Nov;2009(11):pdb.prot5315. doi: 10.1101/pdb.prot5315.

PMID:
20150054
46.

An internal signal sequence directs intramembrane proteolysis of a cellular immunoglobulin domain protein.

Robakis T, Bak B, Lin SH, Bernard DJ, Scheiffele P.

J Biol Chem. 2008 Dec 26;283(52):36369-76. doi: 10.1074/jbc.M807527200. Epub 2008 Nov 3.

47.

Neuronal polarity, the establishment and function of neuronal subdomains, and how these are prominent targets of disease. Editorial overview.

Caroni P, Scheiffele P.

Curr Opin Neurobiol. 2008 Oct;18(5):469-71. doi: 10.1016/j.conb.2008.10.004. Epub 2008 Nov 6. No abstract available.

PMID:
18977302
48.

Neuroligin-1 is required for normal expression of LTP and associative fear memory in the amygdala of adult animals.

Kim J, Jung SY, Lee YK, Park S, Choi JS, Lee CJ, Kim HS, Choi YB, Scheiffele P, Bailey CH, Kandel ER, Kim JH.

Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):9087-92. doi: 10.1073/pnas.0803448105. Epub 2008 Jun 25.

49.

GABA and neuroligin signaling: linking synaptic activity and adhesion in inhibitory synapse development.

Huang ZJ, Scheiffele P.

Curr Opin Neurobiol. 2008 Feb;18(1):77-83. doi: 10.1016/j.conb.2008.05.008. Epub 2008 May 29. Review.

50.

Crystal structures of beta-neurexin 1 and beta-neurexin 2 ectodomains and dynamics of splice insertion sequence 4.

Koehnke J, Jin X, Trbovic N, Katsamba PS, Brasch J, Ahlsen G, Scheiffele P, Honig B, Palmer AG 3rd, Shapiro L.

Structure. 2008 Mar;16(3):410-21. doi: 10.1016/j.str.2007.12.024.

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