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Items: 1 to 50 of 100

1.

Serum amyloid A1 mediates myotube atrophy via Toll-like receptors.

Hahn A, Kny M, Pablo-Tortola C, Todiras M, Willenbrock M, Schmidt S, Schmoeckel K, Jorde I, Nowak M, Jarosch E, Sommer T, Bröker BM, Felix SB, Scheidereit C, Weber-Carstens S, Butter C, Luft FC, Fielitz J.

J Cachexia Sarcopenia Muscle. 2019 Aug 23. doi: 10.1002/jcsm.12491. [Epub ahead of print]

2.

Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma.

von Hoff L, Kärgel E, Franke V, McShane E, Schulz-Beiss KW, Patone G, Schleussner N, Kolesnichenko M, Hübner N, Daumke O, Selbach M, Akalin A, Mathas S, Scheidereit C.

Blood. 2019 Mar 28;133(13):1489-1494. doi: 10.1182/blood-2018-08-871293. Epub 2019 Jan 29.

PMID:
30696620
3.

The IκB kinase complex is a regulator of mRNA stability.

Mikuda N, Kolesnichenko M, Beaudette P, Popp O, Uyar B, Sun W, Tufan AB, Perder B, Akalin A, Chen W, Mertins P, Dittmar G, Hinz M, Scheidereit C.

EMBO J. 2018 Dec 14;37(24). pii: e98658. doi: 10.15252/embj.201798658. Epub 2018 Nov 22.

PMID:
30467221
4.

The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma.

Schleussner N, Merkel O, Costanza M, Liang HC, Hummel F, Romagnani C, Durek P, Anagnostopoulos I, Hummel M, Jöhrens K, Niedobitek A, Griffin PR, Piva R, Sczakiel HL, Woessmann W, Damm-Welk C, Hinze C, Stoiber D, Gillissen B, Turner SD, Kaergel E, von Hoff L, Grau M, Lenz G, Dörken B, Scheidereit C, Kenner L, Janz M, Mathas S.

Leukemia. 2018 Sep;32(9):1994-2007. doi: 10.1038/s41375-018-0045-9. Epub 2018 Mar 28.

5.

NF-κB Participates in Mouse Hair Cycle Control and Plays Distinct Roles in the Various Pelage Hair Follicle Types.

Krieger K, Millar SE, Mikuda N, Krahn I, Kloepper JE, Bertolini M, Scheidereit C, Paus R, Schmidt-Ullrich R.

J Invest Dermatol. 2018 Feb;138(2):256-264. doi: 10.1016/j.jid.2017.08.042. Epub 2017 Sep 20. Erratum in: J Invest Dermatol. 2018 Sep;138(9):2084.

6.

Endothelial NF-κB Blockade Abrogates ANCA-Induced GN.

Choi M, Schreiber A, Eulenberg-Gustavus C, Scheidereit C, Kamps J, Kettritz R.

J Am Soc Nephrol. 2017 Nov;28(11):3191-3204. doi: 10.1681/ASN.2016060690. Epub 2017 Jul 7.

7.

A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: Dominant roles of p50 and p52 revealed by genome-wide analyses.

de Oliveira KA, Kaergel E, Heinig M, Fontaine JF, Patone G, Muro EM, Mathas S, Hummel M, Andrade-Navarro MA, Hübner N, Scheidereit C.

Genome Med. 2016 Mar 17;8(1):28. doi: 10.1186/s13073-016-0280-5.

8.

Lhx2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth.

Tomann P, Paus R, Millar SE, Scheidereit C, Schmidt-Ullrich R.

Development. 2016 May 1;143(9):1512-22. doi: 10.1242/dev.130898. Epub 2016 Mar 7.

9.

Tubular Epithelial NF-κB Activity Regulates Ischemic AKI.

Markó L, Vigolo E, Hinze C, Park JK, Roël G, Balogh A, Choi M, Wübken A, Cording J, Blasig IE, Luft FC, Scheidereit C, Schmidt-Ott KM, Schmidt-Ullrich R, Müller DN.

J Am Soc Nephrol. 2016 Sep;27(9):2658-69. doi: 10.1681/ASN.2015070748. Epub 2016 Jan 28.

10.

RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway.

Murakawa Y, Hinz M, Mothes J, Schuetz A, Uhl M, Wyler E, Yasuda T, Mastrobuoni G, Friedel CC, Dölken L, Kempa S, Schmidt-Supprian M, Blüthgen N, Backofen R, Heinemann U, Wolf J, Scheidereit C, Landthaler M.

Nat Commun. 2015 Jul 14;6:7367. doi: 10.1038/ncomms8367.

11.

Quantitative dissection and modeling of the NF-κB p100-p105 module reveals interdependent precursor proteolysis.

Yılmaz ZB, Kofahl B, Beaudette P, Baum K, Ipenberg I, Weih F, Wolf J, Dittmar G, Scheidereit C.

Cell Rep. 2014 Dec 11;9(5):1756-1769. doi: 10.1016/j.celrep.2014.11.014. Epub 2014 Dec 4.

12.

Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma.

Kreher S, Bouhlel MA, Cauchy P, Lamprecht B, Li S, Grau M, Hummel F, Köchert K, Anagnostopoulos I, Jöhrens K, Hummel M, Hiscott J, Wenzel SS, Lenz P, Schneider M, Küppers R, Scheidereit C, Giefing M, Siebert R, Rajewsky K, Lenz G, Cockerill PN, Janz M, Dörken B, Bonifer C, Mathas S.

Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4513-22. doi: 10.1073/pnas.1406985111. Epub 2014 Oct 6.

13.

The IκB kinase complex in NF-κB regulation and beyond.

Hinz M, Scheidereit C.

EMBO Rep. 2014 Jan;15(1):46-61. doi: 10.1002/embr.201337983. Epub 2013 Dec 27. Review.

14.

IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL.

Nogai H, Wenzel SS, Hailfinger S, Grau M, Kaergel E, Seitz V, Wollert-Wulf B, Pfeifer M, Wolf A, Frick M, Dietze K, Madle H, Tzankov A, Hummel M, Dörken B, Scheidereit C, Janz M, Lenz P, Thome M, Lenz G.

Blood. 2013 Sep 26;122(13):2242-50. doi: 10.1182/blood-2013-06-508028. Epub 2013 Jul 18.

15.

It takes two to tango: IκBs, the multifunctional partners of NF-κB.

Hinz M, Arslan SÇ, Scheidereit C.

Immunol Rev. 2012 Mar;246(1):59-76. doi: 10.1111/j.1600-065X.2012.01102.x. Review.

PMID:
22435547
16.

The prevalence of TNFα-induced necrosis over apoptosis is determined by TAK1-RIP1 interplay.

Arslan SÇ, Scheidereit C.

PLoS One. 2011;6(10):e26069. doi: 10.1371/journal.pone.0026069. Epub 2011 Oct 10.

17.

Opposing roles of NF-κB in anti-cancer treatment outcome unveiled by cross-species investigations.

Jing H, Kase J, Dörr JR, Milanovic M, Lenze D, Grau M, Beuster G, Ji S, Reimann M, Lenz P, Hummel M, Dörken B, Lenz G, Scheidereit C, Schmitt CA, Lee S.

Genes Dev. 2011 Oct 15;25(20):2137-46. doi: 10.1101/gad.17620611. Epub 2011 Oct 6.

18.

A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.

Hinz M, Stilmann M, Arslan SÇ, Khanna KK, Dittmar G, Scheidereit C.

Mol Cell. 2010 Oct 8;40(1):63-74. doi: 10.1016/j.molcel.2010.09.008.

19.

A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IkappaB kinase activation.

Stilmann M, Hinz M, Arslan SC, Zimmer A, Schreiber V, Scheidereit C.

Mol Cell. 2009 Nov 13;36(3):365-78. doi: 10.1016/j.molcel.2009.09.032.

20.

Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction.

Zhang Y, Tomann P, Andl T, Gallant NM, Huelsken J, Jerchow B, Birchmeier W, Paus R, Piccolo S, Mikkola ML, Morrisey EE, Overbeek PA, Scheidereit C, Millar SE, Schmidt-Ullrich R.

Dev Cell. 2009 Jul;17(1):49-61. doi: 10.1016/j.devcel.2009.05.011.

21.

Identification of a chemokine receptor profile characteristic for mediastinal large B-cell lymphoma.

Rehm A, Anagnostopoulos I, Gerlach K, Broemer M, Scheidereit C, Jöhrens K, Hübler M, Hetzer R, Stein H, Lipp M, Dörken B, Höpken UE.

Int J Cancer. 2009 Nov 15;125(10):2367-74. doi: 10.1002/ijc.24652.

22.

Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation.

Oeckinghaus A, Wegener E, Welteke V, Ferch U, Arslan SC, Ruland J, Scheidereit C, Krappmann D.

EMBO J. 2007 Nov 14;26(22):4634-45. Epub 2007 Oct 18.

23.

Signal responsiveness of IkappaB kinases is determined by Cdc37-assisted transient interaction with Hsp90.

Hinz M, Broemer M, Arslan SC, Otto A, Mueller EC, Dettmer R, Scheidereit C.

J Biol Chem. 2007 Nov 2;282(44):32311-9. Epub 2007 Aug 29.

24.

High expression of RelA/p65 is associated with activation of nuclear factor-kappaB-dependent signaling in pancreatic cancer and marks a patient population with poor prognosis.

Weichert W, Boehm M, Gekeler V, Bahra M, Langrehr J, Neuhaus P, Denkert C, Imre G, Weller C, Hofmann HP, Niesporek S, Jacob J, Dietel M, Scheidereit C, Kristiansen G.

Br J Cancer. 2007 Aug 20;97(4):523-30. Epub 2007 Jul 10.

25.

Vascular endothelial cell-specific NF-kappaB suppression attenuates hypertension-induced renal damage.

Henke N, Schmidt-Ullrich R, Dechend R, Park JK, Qadri F, Wellner M, Obst M, Gross V, Dietz R, Luft FC, Scheidereit C, Muller DN.

Circ Res. 2007 Aug 3;101(3):268-76. Epub 2007 Jun 21.

PMID:
17585070
26.

Striking back at the activator: how IkappaB kinase terminates antigen receptor responses.

Hinz M, Scheidereit C.

Sci STKE. 2007 May 1;2007(384):pe19.

PMID:
17473308
27.

IkappaB kinase complexes: gateways to NF-kappaB activation and transcription.

Scheidereit C.

Oncogene. 2006 Oct 30;25(51):6685-705. Review.

PMID:
17072322
28.
29.

NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth.

Schmidt-Ullrich R, Tobin DJ, Lenhard D, Schneider P, Paus R, Scheidereit C.

Development. 2006 Mar;133(6):1045-57. Epub 2006 Feb 15.

30.

Elevated NF-kappaB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large-cell, and other peripheral T-cell lymphomas.

Mathas S, Jöhrens K, Joos S, Lietz A, Hummel F, Janz M, Jundt F, Anagnostopoulos I, Bommert K, Lichter P, Stein H, Scheidereit C, Dörken B.

Blood. 2005 Dec 15;106(13):4287-93. Epub 2005 Aug 25.

31.

Requirement of nuclear factor-kappaB in angiotensin II- and isoproterenol-induced cardiac hypertrophy in vivo.

Freund C, Schmidt-Ullrich R, Baurand A, Dunger S, Schneider W, Loser P, El-Jamali A, Dietz R, Scheidereit C, Bergmann MW.

Circulation. 2005 May 10;111(18):2319-25. Epub 2005 May 3.

PMID:
15870116
32.

Regulation of vascular smooth muscle cell proliferation: role of NF-kappaB revisited.

Mehrhof FB, Schmidt-Ullrich R, Dietz R, Scheidereit C.

Circ Res. 2005 May 13;96(9):958-64. Epub 2005 Apr 14.

PMID:
15831813
33.
34.

The effect of fever-like temperatures on neutrophil signaling.

Salanova B, Choi M, Rolle S, Wellner M, Scheidereit C, Luft FC, Kettritz R.

FASEB J. 2005 May;19(7):816-8. Epub 2005 Mar 8.

PMID:
15755871
35.

The IkappaB kinase complex and NF-kappaB act as master regulators of lipopolysaccharide-induced gene expression and control subordinate activation of AP-1.

Krappmann D, Wegener E, Sunami Y, Esen M, Thiel A, Mordmuller B, Scheidereit C.

Mol Cell Biol. 2004 Jul;24(14):6488-500.

36.

Reoxygenation after severe hypoxia induces cardiomyocyte hypertrophy in vitro: activation of CREB downstream of GSK3beta.

El Jamali A, Freund C, Rechner C, Scheidereit C, Dietz R, Bergmann MW.

FASEB J. 2004 Jul;18(10):1096-8. Epub 2004 May 20.

PMID:
15155564
37.
38.

A dual role for Ikk alpha in tooth development.

Ohazama A, Hu Y, Schmidt-Ullrich R, Cao Y, Scheidereit C, Karin M, Sharpe PT.

Dev Cell. 2004 Feb;6(2):219-27.

39.

Inhibition of NF-kappaB by a TAT-NEMO-binding domain peptide accelerates constitutive apoptosis and abrogates LPS-delayed neutrophil apoptosis.

Choi M, Rolle S, Wellner M, Cardoso MC, Scheidereit C, Luft FC, Kettritz R.

Blood. 2003 Sep 15;102(6):2259-67. Epub 2003 May 22.

40.

Inhibition of NF-kappaB essentially contributes to arsenic-induced apoptosis.

Mathas S, Lietz A, Janz M, Hinz M, Jundt F, Scheidereit C, Bommert K, Dorken B.

Blood. 2003 Aug 1;102(3):1028-34. Epub 2003 Apr 3.

41.
42.

Lymphotoxin and lipopolysaccharide induce NF-kappaB-p52 generation by a co-translational mechanism.

Mordmüller B, Krappmann D, Esen M, Wegener E, Scheidereit C.

EMBO Rep. 2003 Jan;4(1):82-7.

43.

Nuclear factor kappaB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity.

Hinz M, Lemke P, Anagnostopoulos I, Hacker C, Krappmann D, Mathas S, Dörken B, Zenke M, Stein H, Scheidereit C.

J Exp Med. 2002 Sep 2;196(5):605-17.

44.

Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B.

Mathas S, Hinz M, Anagnostopoulos I, Krappmann D, Lietz A, Jundt F, Bommert K, Mechta-Grigoriou F, Stein H, Dörken B, Scheidereit C.

EMBO J. 2002 Aug 1;21(15):4104-13.

45.

Loss of PU.1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease.

Jundt F, Kley K, Anagnostopoulos I, Schulze Pröbsting K, Greiner A, Mathas S, Scheidereit C, Wirth T, Stein H, Dörken B.

Blood. 2002 Apr 15;99(8):3060-2.

46.

Purification and characterization of the human elongator complex.

Hawkes NA, Otero G, Winkler GS, Marshall N, Dahmus ME, Krappmann D, Scheidereit C, Thomas CL, Schiavo G, Erdjument-Bromage H, Tempst P, Svejstrup JQ.

J Biol Chem. 2002 Jan 25;277(4):3047-52. Epub 2001 Nov 19.

47.

Requirement of NF-kappaB/Rel for the development of hair follicles and other epidermal appendices.

Schmidt-Ullrich R, Aebischer T, Hülsken J, Birchmeier W, Klemm U, Scheidereit C.

Development. 2001 Oct;128(19):3843-53.

48.
49.

Aspirin inhibits NF-kappaB and protects from angiotensin II-induced organ damage.

Muller DN, Heissmeyer V, Dechend R, Hampich F, Park JK, Fiebeler A, Shagdarsuren E, Theuer J, Elger M, Pilz B, Breu V, Schroer K, Ganten D, Dietz R, Haller H, Scheidereit C, Luft FC.

FASEB J. 2001 Aug;15(10):1822-4. No abstract available.

PMID:
11481242
50.

In vitro susceptibility to TRAIL-induced apoptosis of acute leukemia cells in the context of TRAIL receptor gene expression and constitutive NF-kappa B activity.

Wuchter C, Krappmann D, Cai Z, Ruppert V, Scheidereit C, Dörken B, Ludwig WD, Karawajew L.

Leukemia. 2001 Jun;15(6):921-8.

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