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Items: 1 to 50 of 84

1.

Wnt signaling: implications in endoderm development and pancreas organogenesis.

Scheibner K, Bakhti M, Bastidas-Ponce A, Lickert H.

Curr Opin Cell Biol. 2019 Aug 1;61:48-55. doi: 10.1016/j.ceb.2019.07.002. [Epub ahead of print] Review.

PMID:
31377680
2.

Pre-marked chromatin and transcription factor co-binding shape the pioneering activity of Foxa2.

Cernilogar FM, Hasenöder S, Wang Z, Scheibner K, Burtscher I, Sterr M, Smialowski P, Groh S, Evenroed IM, Gilfillan GD, Lickert H, Schotta G.

Nucleic Acids Res. 2019 Sep 26;47(17):9069-9086. doi: 10.1093/nar/gkz627.

3.

Comprehensive single cell mRNA profiling reveals a detailed roadmap for pancreatic endocrinogenesis.

Bastidas-Ponce A, Tritschler S, Dony L, Scheibner K, Tarquis-Medina M, Salinno C, Schirge S, Burtscher I, Böttcher A, Theis FJ, Lickert H, Bakhti M.

Development. 2019 Jun 17;146(12). pii: dev173849. doi: 10.1242/dev.173849.

PMID:
31160421
4.

Metabolic activity testing can underestimate acute drug cytotoxicity as revealed by HepG2 cell clones overexpressing cytochrome P450 2C19 and 3A4.

Steinbrecht S, König R, Schmidtke KU, Herzog N, Scheibner K, Krüger-Genge A, Jung F, Kammerer S, Küpper JH.

Toxicology. 2019 Jan 15;412:37-47. doi: 10.1016/j.tox.2018.11.008. Epub 2018 Nov 27.

PMID:
30500380
5.

Side chain removal from corticosteroids by unspecific peroxygenase.

Ullrich R, Poraj-Kobielska M, Scholze S, Halbout C, Sandvoss M, Pecyna MJ, Scheibner K, Hofrichter M.

J Inorg Biochem. 2018 Jun;183:84-93. doi: 10.1016/j.jinorgbio.2018.03.011. Epub 2018 Mar 26.

6.

2017 White Paper on recent issues in bioanalysis: a global perspective on immunogenicity guidelines & biomarker assay performance (Part 3 - LBA: immunogenicity, biomarkers and PK assays).

Gupta S, Richards S, Amaravadi L, Piccoli S, Desilva B, Pillutla R, Stevenson L, Mehta D, Carrasco-Triguero M, Neely R, Partridge M, Staack RF, Zhao X, Gorovits B, Kolaitis G, Sumner G, Stubenrauch KG, Zou L, Amur S, Beaver C, Berger I, Berisha F, Birnboeck H, Bower J, Cho SJ, Cludts I, Cocea L, Donato LD, Fischer S, Fraser S, Garofolo F, Haidar S, Haulenbeek J, Hottenstein C, Hu J, Ishii-Watabe A, Islam R, Jani D, Kadavil J, Kamerud J, Kramer D, Kurki P, MacMannis S, McNally J, Mullan A, Papadimitriou A, Pedras-Vasconcelos J, Ray S, Safavi A, Saito Y, Savoie N, Fjording MS, Scheibner K, Smeraglia J, Song A, Stouffer B, Tampal N, der Strate BV, Verch T, Welink J, Xu Y, Yang TY, Yengi L, Zeng J, Zhang Y, Zhang Y, Zoog S.

Bioanalysis. 2017 Dec;9(24):1967-1996. doi: 10.4155/bio-2017-4974. Epub 2017 Dec 5.

7.

Fatty Acid Chain Shortening by a Fungal Peroxygenase.

Olmedo A, Río JCD, Kiebist J, Ullrich R, Hofrichter M, Scheibner K, Martínez AT, Gutiérrez A.

Chemistry. 2017 Dec 1;23(67):16985-16989. doi: 10.1002/chem.201704773. Epub 2017 Nov 20.

8.

Fungal Unspecific Peroxygenases Oxidize the Majority of Organic EPA Priority Pollutants.

Karich A, Ullrich R, Scheibner K, Hofrichter M.

Front Microbiol. 2017 Aug 9;8:1463. doi: 10.3389/fmicb.2017.01463. eCollection 2017.

9.

Cellular and molecular mechanisms coordinating pancreas development.

Bastidas-Ponce A, Scheibner K, Lickert H, Bakhti M.

Development. 2017 Aug 15;144(16):2873-2888. doi: 10.1242/dev.140756. Review.

10.

Oxidoreductases on their way to industrial biotransformations.

Martínez AT, Ruiz-Dueñas FJ, Camarero S, Serrano A, Linde D, Lund H, Vind J, Tovborg M, Herold-Majumdar OM, Hofrichter M, Liers C, Ullrich R, Scheibner K, Sannia G, Piscitelli A, Pezzella C, Sener ME, Kılıç S, van Berkel WJH, Guallar V, Lucas MF, Zuhse R, Ludwig R, Hollmann F, Fernández-Fueyo E, Record E, Faulds CB, Tortajada M, Winckelmann I, Rasmussen JA, Gelo-Pujic M, Gutiérrez A, Del Río JC, Rencoret J, Alcalde M.

Biotechnol Adv. 2017 Nov 1;35(6):815-831. doi: 10.1016/j.biotechadv.2017.06.003. Epub 2017 Jun 15. Review.

11.

A Peroxygenase from Chaetomium globosum Catalyzes the Selective Oxygenation of Testosterone.

Kiebist J, Schmidtke KU, Zimmermann J, Kellner H, Jehmlich N, Ullrich R, Zänder D, Hofrichter M, Scheibner K.

Chembiochem. 2017 Mar 16;18(6):563-569. doi: 10.1002/cbic.201600677. Epub 2017 Mar 1.

12.

2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV): (Part 3 - LBA, biomarkers and immunogenicity).

Richards S, Amaravadi L, Pillutla R, Birnboeck H, Torri A, Cowan KJ, Papadimitriou A, Garofolo F, Satterwhite C, Piccoli S, Wu B, Krinos-Fiorotti C, Allinson J, Berisha F, Cocea L, Croft S, Fraser S, Galliccia F, Gorovits B, Gupta S, Gupta V, Haidar S, Hottenstein C, Ishii-Watabe A, Jani D, Kadavil J, Kamerud J, Kramer D, Litwin V, Lima Santos GM, Nelson R, Ni Y, Pedras-Vasconcelos J, Qiu Y, Rhyne P, Safavi A, Saito Y, Savoie N, Scheibner K, Schick E, Siguenza PY, Smeraglia J, Staack RF, Subramanyam M, Sumner G, Thway T, Uhlinger D, Ullmann M, Vitaliti A, Welink J, Whiting CC, Xue L, Zeng R.

Bioanalysis. 2016 Dec;8(23):2475-2496.

13.

2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV): (Part 2 - Hybrid LBA/LCMS and input from regulatory agencies).

Song A, Lee A, Garofolo F, Kaur S, Duggan J, Evans C, Palandra J, Donato LD, Xu K, Bauer R, Bustard M, Chen L, Cocea L, Croft S, Galliccia F, Haidar S, Hughes N, Ishii-Watabe A, Islam R, Jones B, Kadavil J, Krantz C, Lima Santos GM, Olah T, Pedras-Vasconcelos J, Staelens L, Saito Y, Savoie N, Scheibner K, Spitz S, Tampal N, Thomas E, Vinter S, Wakelin-Smith J, Welink J, Zeng J, Zhou S.

Bioanalysis. 2016 Dec;8(23):2457-2474.

14.

From Alkanes to Carboxylic Acids: Terminal Oxygenation by a Fungal Peroxygenase.

Olmedo A, Aranda C, Del Río JC, Kiebist J, Scheibner K, Martínez AT, Gutiérrez A.

Angew Chem Int Ed Engl. 2016 Sep 26;55(40):12248-51. doi: 10.1002/anie.201605430. Epub 2016 Aug 30.

PMID:
27573441
15.

Bioanalytical inspections: organizational changes and regulatory perspectives.

Haidar SH, Scheibner KA.

Bioanalysis. 2016 May;8(10):999-1002. doi: 10.4155/bio-2016-0052. Epub 2016 Apr 15. No abstract available.

16.

Back to "once a caesarean: always a caesarean"? A trend analysis in Switzerland.

Christmann-Schmid C, Raio L, Scheibner K, Müller M, Surbek D.

Arch Gynecol Obstet. 2016 Nov;294(5):905-910. Epub 2016 Mar 15.

PMID:
26980229
17.

Primary-like human hepatocytes genetically engineered to obtain proliferation competence display hepatic differentiation characteristics in monolayer and organotypical spheroid cultures.

Herzog N, Hansen M, Miethbauer S, Schmidtke KU, Anderer U, Lupp A, Sperling S, Seehofer D, Damm G, Scheibner K, Küpper JH.

Cell Biol Int. 2016 Mar;40(3):341-53. doi: 10.1002/cbin.10574. Epub 2016 Jan 18.

PMID:
26715207
18.

One-pot synthesis of human metabolites of SAR548304 by fungal peroxygenases.

Kiebist J, Holla W, Heidrich J, Poraj-Kobielska M, Sandvoss M, Simonis R, Gröbe G, Atzrodt J, Hofrichter M, Scheibner K.

Bioorg Med Chem. 2015 Aug 1;23(15):4324-32. doi: 10.1016/j.bmc.2015.06.035. Epub 2015 Jun 19.

PMID:
26142319
19.

Steroid hydroxylation by basidiomycete peroxygenases: a combined experimental and computational study.

Babot ED, Del Río JC, Cañellas M, Sancho F, Lucas F, Guallar V, Kalum L, Lund H, Gröbe G, Scheibner K, Ullrich R, Hofrichter M, Martínez AT, Gutiérrez A.

Appl Environ Microbiol. 2015 Jun 15;81(12):4130-42. doi: 10.1128/AEM.00660-15. Epub 2015 Apr 10.

20.

c-MYC Generates Repair Errors via Increased Transcription of Alternative-NHEJ Factors, LIG3 and PARP1, in Tyrosine Kinase-Activated Leukemias.

Muvarak N, Kelley S, Robert C, Baer MR, Perrotti D, Gambacorti-Passerini C, Civin C, Scheibner K, Rassool FV.

Mol Cancer Res. 2015 Apr;13(4):699-712. doi: 10.1158/1541-7786.MCR-14-0422. Epub 2015 Mar 31.

21.

Preparation of labeled human drug metabolites and drug-drug interaction-probes with fungal peroxygenases.

Poraj-Kobielska M, Atzrodt J, Holla W, Sandvoss M, Gröbe G, Scheibner K, Hofrichter M.

J Labelled Comp Radiopharm. 2013 Jul-Aug;56(9-10):513-9. doi: 10.1002/jlcr.3103. Epub 2013 Aug 29.

PMID:
24285530
22.

Structural basis of substrate conversion in a new aromatic peroxygenase: cytochrome P450 functionality with benefits.

Piontek K, Strittmatter E, Ullrich R, Gröbe G, Pecyna MJ, Kluge M, Scheibner K, Hofrichter M, Plattner DA.

J Biol Chem. 2013 Nov 29;288(48):34767-76. doi: 10.1074/jbc.M113.514521. Epub 2013 Oct 14.

23.

Missed opportunities among HIV-positive women to control viral replication during pregnancy and to have a vaginal delivery.

Aebi-Popp K, Mulcahy F, Glass TR, Rudin C, Martinez de Tejada B, Bertisch B, Fehr J, Grawe C, Scheibner K, Rickenbach M, Hoesli I, Thorne C; European Collaborative Study in EuroCoord; Swiss Mother & Child HIV Cohort Study.

J Acquir Immune Defic Syndr. 2013 Sep 1;64(1):58-65. doi: 10.1097/QAI.0b013e3182a334e3.

PMID:
23842074
24.

Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile.

Cramer-Morales K, Nieborowska-Skorska M, Scheibner K, Padget M, Irvine DA, Sliwinski T, Haas K, Lee J, Geng H, Roy D, Slupianek A, Rassool FV, Wasik MA, Childers W, Copland M, Müschen M, Civin CI, Skorski T.

Blood. 2013 Aug 15;122(7):1293-304. doi: 10.1182/blood-2013-05-501072. Epub 2013 Jul 8.

25.

MiR-27a functions as a tumor suppressor in acute leukemia by regulating 14-3-3θ.

Scheibner KA, Teaboldt B, Hauer MC, Chen X, Cherukuri S, Guo Y, Kelley SM, Liu Z, Baer MR, Heimfeld S, Civin CI.

PLoS One. 2012;7(12):e50895. doi: 10.1371/journal.pone.0050895. Epub 2012 Dec 7.

26.

Regulation of human RNase-L by the miR-29 family reveals a novel oncogenic role in chronic myelogenous leukemia.

Lee TY, Ezelle HJ, Venkataraman T, Lapidus RG, Scheibner KA, Hassel BA.

J Interferon Cytokine Res. 2013 Jan;33(1):34-42. doi: 10.1089/jir.2012.0062. Epub 2012 Oct 31.

27.

The aromatic peroxygenase from Marasmius rutola--a new enzyme for biosensor applications.

Yarman A, Gröbe G, Neumann B, Kinne M, Gajovic-Eichelmann N, Wollenberger U, Hofrichter M, Ullrich R, Scheibner K, Scheller FW.

Anal Bioanal Chem. 2012 Jan;402(1):405-12. doi: 10.1007/s00216-011-5497-y. Epub 2011 Oct 25.

PMID:
22038589
28.

A spectrophotometric assay for the detection of fungal peroxygenases.

Poraj-Kobielska M, Kinne M, Ullrich R, Scheibner K, Hofrichter M.

Anal Biochem. 2012 Feb 1;421(1):327-9. doi: 10.1016/j.ab.2011.10.009. Epub 2011 Oct 8.

PMID:
22037293
29.

High-yield production of aromatic peroxygenase by the agaric fungus Marasmius rotula.

Gröbe G, Ullrich R, Pecyna MJ, Kapturska D, Friedrich S, Hofrichter M, Scheibner K.

AMB Express. 2011 Oct 11;1(1):31. doi: 10.1186/2191-0855-1-31.

30.

[Complex umbilical cord vein pulsations in cases with twin-twin transfusion syndrome: prognostic implications].

Scheibner K, Kuhn P, Surbek D, Raio L.

Ultraschall Med. 2011 Dec;32 Suppl 2:E157-61. doi: 10.1055/s-0031-1273469. Epub 2011 Aug 29. German.

PMID:
21877316
31.

Preparation of human drug metabolites using fungal peroxygenases.

Poraj-Kobielska M, Kinne M, Ullrich R, Scheibner K, Kayser G, Hammel KE, Hofrichter M.

Biochem Pharmacol. 2011 Oct 1;82(7):789-96. doi: 10.1016/j.bcp.2011.06.020. Epub 2011 Jun 23.

PMID:
21723855
32.

Peroxygenase based sensor for aromatic compounds.

Peng L, Wollenberger U, Kinne M, Hofrichter M, Ullrich R, Scheibner K, Fischer A, Scheller FW.

Biosens Bioelectron. 2010 Dec 15;26(4):1432-6. doi: 10.1016/j.bios.2010.07.075. Epub 2010 Jul 29.

PMID:
20719491
33.

Molecular characterization of aromatic peroxygenase from Agrocybe aegerita.

Pecyna MJ, Ullrich R, Bittner B, Clemens A, Scheibner K, Schubert R, Hofrichter M.

Appl Microbiol Biotechnol. 2009 Oct;84(5):885-97. doi: 10.1007/s00253-009-2000-1. Epub 2009 May 12.

PMID:
19434406
34.

Regioselective preparation of 5-hydroxypropranolol and 4'-hydroxydiclofenac with a fungal peroxygenase.

Kinne M, Poraj-Kobielska M, Aranda E, Ullrich R, Hammel KE, Scheibner K, Hofrichter M.

Bioorg Med Chem Lett. 2009 Jun 1;19(11):3085-7. doi: 10.1016/j.bmcl.2009.04.015. Epub 2009 Apr 9.

PMID:
19394224
35.

Anti-oxidant inhibition of hyaluronan fragment-induced inflammatory gene expression.

Eberlein M, Scheibner KA, Black KE, Collins SL, Chan-Li Y, Powell JD, Horton MR.

J Inflamm (Lond). 2008 Nov 5;5:20. doi: 10.1186/1476-9255-5-20.

36.

Hydroxylation of naphthalene by aromatic peroxygenase from Agrocybe aegerita proceeds via oxygen transfer from H2O2 and intermediary epoxidation.

Kluge M, Ullrich R, Dolge C, Scheibner K, Hofrichter M.

Appl Microbiol Biotechnol. 2009 Jan;81(6):1071-6. doi: 10.1007/s00253-008-1704-y. Epub 2008 Sep 25.

PMID:
18815784
37.

The adenosine a2a receptor inhibits matrix-induced inflammation in a novel fashion.

Scheibner KA, Boodoo S, Collins S, Black KE, Chan-Li Y, Zarek P, Powell JD, Horton MR.

Am J Respir Cell Mol Biol. 2009 Mar;40(3):251-9. doi: 10.1165/rcmb.2008-0168OC. Epub 2008 Aug 14.

38.

Spectrophotometric assay for detection of aromatic hydroxylation catalyzed by fungal haloperoxidase-peroxygenase.

Kluge MG, Ullrich R, Scheibner K, Hofrichter M.

Appl Microbiol Biotechnol. 2007 Jul;75(6):1473-8. Epub 2007 Apr 5.

PMID:
17410351
39.

Hyaluronan fragments act as an endogenous danger signal by engaging TLR2.

Scheibner KA, Lutz MA, Boodoo S, Fenton MJ, Powell JD, Horton MR.

J Immunol. 2006 Jul 15;177(2):1272-81.

40.

Enzymatic Combustion of Aromatic and Aliphatic Compounds by Manganese Peroxidase from Nematoloma frowardii.

Hofrichter M, Scheibner K, Schneegass I, Fritsche W.

Appl Environ Microbiol. 1998 Feb;64(2):399-404.

41.

Novel haloperoxidase from the agaric basidiomycete Agrocybe aegerita oxidizes aryl alcohols and aldehydes.

Ullrich R, Nüske J, Scheibner K, Spantzel J, Hofrichter M.

Appl Environ Microbiol. 2004 Aug;70(8):4575-81.

42.

Conversion of adamsite (phenarsarzin chloride) by fungal manganese peroxidase.

Haas R, Tsivunchyk O, Steinbach K, von Löw E, Scheibner K, Hofrichter M.

Appl Microbiol Biotechnol. 2004 Feb;63(5):564-6. Epub 2003 Oct 16.

PMID:
14564485
43.
44.

Investigation of the roles of catalytic residues in serotonin N-acetyltransferase.

Scheibner KA, De Angelis J, Burley SK, Cole PA.

J Biol Chem. 2002 May 17;277(20):18118-26. Epub 2002 Mar 7.

45.

Mechanistic studies on the alkyltransferase activity of serotonin N-acetyltransferase.

Zheng W, Scheibner KA, Ho AK, Cole PA.

Chem Biol. 2001 Apr;8(4):379-89.

46.

Transformation and mineralization of 2,4,6-trinitrotoluene (TNT) by manganese peroxidase from the white-rot basidiomycete Phlebia radiata.

Van Aken B, Hofrichter M, Scheibner K, Hatakka AI, Naveau H, Agathos SN.

Biodegradation. 1999 Apr;10(2):83-91.

PMID:
10466197
47.
48.

Conversion of aminonitrotoluenes by fungal manganese peroxidase.

Scheibner K, Hofrichter M.

J Basic Microbiol. 1998;38(1):51-9.

PMID:
9575043
49.

[Fatigue in chewing as the initial symptom of myasthenia gravis in a 81-year-old woman].

de Teresa L, Tello A, Fernández V, Gómez R, Scheibner K.

Rev Neurol. 1997 Dec;25(148):2066-7. Spanish. No abstract available.

PMID:
9528074
50.

Screening for fungi intensively mineralizing 2,4,6-trinitrotoluene.

Scheibner K, Hofrichter M, Herre A, Michels J, Fritsche W.

Appl Microbiol Biotechnol. 1997 Apr;47(4):452-7. Erratum in: Appl Microbiol Biotechnol 1997 Sep;48(3):431.

PMID:
9163958

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