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Items: 24

1.

Cyber risk research impeded by disciplinary barriers.

Falco G, Eling M, Jablanski D, Weber M, Miller V, Gordon LA, Wang SS, Schmit J, Thomas R, Elvedi M, Maillart T, Donavan E, Dejung S, Durand E, Nutter F, Scheffer U, Arazi G, Ohana G, Lin H.

Science. 2019 Nov 29;366(6469):1066-1069. doi: 10.1126/science.aaz4795. No abstract available.

PMID:
31780540
2.

Site-Specific Cleavage of RNAs Derived from the PIM1 3'-UTR by a Metal-Free Artificial Ribonuclease.

Zellmann F, Thomas L, Scheffer U, Hartmann RK, Göbel MW.

Molecules. 2019 Feb 23;24(4). pii: E807. doi: 10.3390/molecules24040807.

3.

Phosphoramidite building blocks with protected nitroxides for the synthesis of spin-labeled DNA and RNA.

Weinrich T, Jaumann EA, Scheffer UM, Prisner TF, Göbel MW.

Beilstein J Org Chem. 2018 Jun 26;14:1563-1569. doi: 10.3762/bjoc.14.133. eCollection 2018.

4.

A Cytidine Phosphoramidite with Protected Nitroxide Spin Label: Synthesis of a Full-Length TAR RNA and Investigation by In-Line Probing and EPR Spectroscopy.

Weinrich T, Jaumann EA, Scheffer U, Prisner TF, Göbel MW.

Chemistry. 2018 Apr 20;24(23):6202-6207. doi: 10.1002/chem.201800167. Epub 2018 Apr 6.

PMID:
29485736
5.

A Bis(guanidinium)alcohol Attached to a Hairpin Polyamide: Synthesis, DNA Binding, and Plasmid Cleavage.

Wirth-Hamdoune D, Ullrich S, Scheffer U, Radanović T, Dürner G, Göbel MW.

Chembiochem. 2016 Mar 15;17(6):506-14. doi: 10.1002/cbic.201500566. Epub 2016 Feb 16.

PMID:
26749155
6.

Fragment based search for small molecule inhibitors of HIV-1 Tat-TAR.

Zeiger M, Stark S, Kalden E, Ackermann B, Ferner J, Scheffer U, Shoja-Bazargani F, Erdel V, Schwalbe H, Göbel MW.

Bioorg Med Chem Lett. 2014 Dec 15;24(24):5576-5580. doi: 10.1016/j.bmcl.2014.11.004. Epub 2014 Nov 6.

PMID:
25466178
7.

Cleavage of phosphodiesters and of DNA by a bis(guanidinium)naphthol acting as a metal-free anion receptor.

Ullrich S, Nazir Z, Büsing A, Scheffer U, Wirth D, Bats JW, Dürner G, Göbel MW.

Chembiochem. 2011 May 16;12(8):1223-9. doi: 10.1002/cbic.201100022. Epub 2011 Apr 15.

PMID:
21500334
8.

Binding sites of the viral RNA element TAR and of TAR mutants for various peptide ligands, probed with LILBID: a new laser mass spectrometry.

Morgner N, Barth HD, Brutschy B, Scheffer U, Breitung S, Göbel M.

J Am Soc Mass Spectrom. 2008 Nov;19(11):1600-11. doi: 10.1016/j.jasms.2008.07.001. Epub 2008 Jul 3.

9.

The concept of template-based de novo design from drug-derived molecular fragments and its application to TAR RNA.

Schüller A, Suhartono M, Fechner U, Tanrikulu Y, Breitung S, Scheffer U, Göbel MW, Schneider G.

J Comput Aided Mol Des. 2008 Feb;22(2):59-68. Epub 2007 Dec 7.

PMID:
18064402
10.

Scaffold hopping by "fuzzy" pharmacophores and its application to RNA targets.

Tanrikulu Y, Nietert M, Scheffer U, Proschak E, Grabowski K, Schneider P, Weidlich M, Karas M, Göbel M, Schneider G.

Chembiochem. 2007 Nov 5;8(16):1932-6. No abstract available.

PMID:
17896338
11.

Tripeptides from synthetic amino acids block the Tat-TAR association and slow down HIV spread in cell cultures.

Ludwig V, Krebs A, Stoll M, Dietrich U, Ferner J, Schwalbe H, Scheffer U, Dürner G, Göbel MW.

Chembiochem. 2007 Oct 15;8(15):1850-6.

PMID:
17886825
12.

Fluorescence correlation spectroscopy at single molecule level on the Tat-TAR complex and its inhibitors.

Nandi CK, Parui PP, Brutschy B, Scheffer U, Göbel M.

Biopolymers. 2008 Jan;89(1):17-25.

PMID:
17764074
13.

Site-specific cleavage of RNA by a metal-free artificial nuclease attached to antisense oligonucleotides.

Gnaccarini C, Peter S, Scheffer U, Vonhoff S, Klussmann S, Göbel MW.

J Am Chem Soc. 2006 Jun 21;128(24):8063-7.

PMID:
16771522
14.

New inhibitors of the Tat-TAR RNA interaction found with a "fuzzy" pharmacophore model.

Renner S, Ludwig V, Boden O, Scheffer U, Göbel M, Schneider G.

Chembiochem. 2005 Jun;6(6):1119-25.

PMID:
15883975
15.

Metal-free catalysts for the hydrolysis of RNA derived from guanidines, 2-aminopyridines, and 2-aminobenzimidazoles.

Scheffer U, Strick A, Ludwig V, Peter S, Kalden E, Göbel MW.

J Am Chem Soc. 2005 Feb 23;127(7):2211-7.

PMID:
15713099
16.

Fluorescence-based on-line detection as an analytical tool in RNA electrophoresis.

Scheffer U, Göbel M.

Methods Mol Biol. 2005;288:261-72.

PMID:
15333909
17.

A peptide template as an allosteric supramolecular catalyst for the cleavage of phosphate esters.

Scarso A, Scheffer U, Göbel M, Broxterman QB, Kaptein B, Formaggio F, Toniolo C, Scrimin P.

Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5144-9. Epub 2002 Apr 9.

18.

Interaction of prion protein mRNA with CBP35 and other cellular proteins: possible implications for prion replication and age-dependent changes.

Müller WE, Scheffer U, Perovic S, Forrest J, Schröder HC.

Arch Gerontol Geriatr. 1997 Jul-Aug;25(1):41-58.

PMID:
15374100
19.
20.

Polymorphism in the immunoglobulin-like domains of the receptor tyrosine kinase from the sponge Geodia cydonium.

Pancer Z, Kruse M, Schäcke H, Scheffer U, Steffen R, Kovács P, Müller WE.

Cell Adhes Commun. 1996 Nov;4(4-5):327-39.

PMID:
9117351
21.

Interaction of 68-kDa TAR RNA-binding protein and other cellular proteins with prion protein-RNA stem-loop.

Scheffer U, Okamoto T, Forrest JM, Rytik PG, Müller WE, Schröder HC.

J Neurovirol. 1995 Dec;1(5-6):391-8.

PMID:
9222382
22.

[Prions].

Scheffer U.

Med Klin (Munich). 1995 Nov 15;90(11):653-7. Review. German. No abstract available.

PMID:
8569634
23.

Impairment of intracellular antiviral defense with age: age-dependent changes in expression of interferon-induced and double-stranded RNA-activated 2-5A synthetase in rat.

Kuusksalu A, Truve E, Aaspollu A, Kelve M, Scheffer U, Müller WE, Schröder HC.

Mech Ageing Dev. 1995 Mar 1;78(2):103-15.

PMID:
7541098
24.

Mode of action of the anti-AIDS compound poly(I).poly(C12U) (Ampligen): activator of 2',5'-oligoadenylate synthetase and double-stranded RNA-dependent kinase.

Ushijima H, Rytik PG, Schäcke H, Scheffer U, Müller WE, Schröder HC.

J Interferon Res. 1993 Apr;13(2):161-71.

PMID:
8099601

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