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Items: 10

1.

Ductal Mucus Obstruction and Reduced Fluid Secretion Are Early Defects in Chronic Pancreatitis.

Balázs A, Balla Z, Kui B, Maléth J, Rakonczay Z Jr, Duerr J, Zhou-Suckow Z, Schatterny J, Sendler M, Mayerle J, Kühn JP, Tiszlavicz L, Mall MA, Hegyi P.

Front Physiol. 2018 May 29;9:632. doi: 10.3389/fphys.2018.00632. eCollection 2018.

2.

Impaired mucus clearance exacerbates allergen-induced type 2 airway inflammation in juvenile mice.

Fritzsching B, Hagner M, Dai L, Christochowitz S, Agrawal R, van Bodegom C, Schmidt S, Schatterny J, Hirtz S, Brown R, Goritzka M, Duerr J, Zhou-Suckow Z, Mall MA.

J Allergy Clin Immunol. 2017 Jul;140(1):190-203.e5. doi: 10.1016/j.jaci.2016.09.045. Epub 2016 Nov 16.

PMID:
27865862
3.

Hypoxic epithelial necrosis triggers neutrophilic inflammation via IL-1 receptor signaling in cystic fibrosis lung disease.

Fritzsching B, Zhou-Suckow Z, Trojanek JB, Schubert SC, Schatterny J, Hirtz S, Agrawal R, Muley T, Kahn N, Sticht C, Gunkel N, Welte T, Randell SH, Länger F, Schnabel P, Herth FJ, Mall MA.

Am J Respir Crit Care Med. 2015 Apr 15;191(8):902-13. doi: 10.1164/rccm.201409-1610OC.

4.

Airway mucus obstruction triggers macrophage activation and matrix metalloproteinase 12-dependent emphysema.

Trojanek JB, Cobos-Correa A, Diemer S, Kormann M, Schubert SC, Zhou-Suckow Z, Agrawal R, Duerr J, Wagner CJ, Schatterny J, Hirtz S, Sommerburg O, Hartl D, Schultz C, Mall MA.

Am J Respir Cell Mol Biol. 2014 Nov;51(5):709-20. doi: 10.1165/rcmb.2013-0407OC.

PMID:
24828142
5.

Lack of neutrophil elastase reduces inflammation, mucus hypersecretion, and emphysema, but not mucus obstruction, in mice with cystic fibrosis-like lung disease.

Gehrig S, Duerr J, Weitnauer M, Wagner CJ, Graeber SY, Schatterny J, Hirtz S, Belaaouaj A, Dalpke AH, Schultz C, Mall MA.

Am J Respir Crit Care Med. 2014 May 1;189(9):1082-92. doi: 10.1164/rccm.201311-1932OC.

PMID:
24678594
6.

Hypertonic saline is effective in the prevention and treatment of mucus obstruction, but not airway inflammation, in mice with chronic obstructive lung disease.

Graeber SY, Zhou-Suckow Z, Schatterny J, Hirtz S, Boucher RC, Mall MA.

Am J Respir Cell Mol Biol. 2013 Sep;49(3):410-7. doi: 10.1165/rcmb.2013-0050OC. Erratum in: Am J Respir Cell Mol Biol. 2014 Apr;50(4):838.

7.

SLC26A9-mediated chloride secretion prevents mucus obstruction in airway inflammation.

Anagnostopoulou P, Riederer B, Duerr J, Michel S, Binia A, Agrawal R, Liu X, Kalitzki K, Xiao F, Chen M, Schatterny J, Hartmann D, Thum T, Kabesch M, Soleimani M, Seidler U, Mall MA.

J Clin Invest. 2012 Oct;122(10):3629-34. doi: 10.1172/JCI60429. Epub 2012 Sep 4.

8.

CFTR regulates early pathogenesis of chronic obstructive lung disease in βENaC-overexpressing mice.

Johannesson B, Hirtz S, Schatterny J, Schultz C, Mall MA.

PLoS One. 2012;7(8):e44059. doi: 10.1371/journal.pone.0044059. Epub 2012 Aug 24.

9.

Allergic airway inflammation induces a pro-secretory epithelial ion transport phenotype in mice.

Anagnostopoulou P, Dai L, Schatterny J, Hirtz S, Duerr J, Mall MA.

Eur Respir J. 2010 Dec;36(6):1436-47. doi: 10.1183/09031936.00181209. Epub 2010 Apr 22. Erratum in: Eur Respir J. 2011 Mar;37(3):727.

10.

Preventive but not late amiloride therapy reduces morbidity and mortality of lung disease in betaENaC-overexpressing mice.

Zhou Z, Treis D, Schubert SC, Harm M, Schatterny J, Hirtz S, Duerr J, Boucher RC, Mall MA.

Am J Respir Crit Care Med. 2008 Dec 15;178(12):1245-56. doi: 10.1164/rccm.200803-442OC. Epub 2008 Oct 10.

PMID:
18849497

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