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Items: 1 to 50 of 53

1.

Integrated Transcriptional Regulatory Network of Quorum Sensing, Replication Control, and SOS Response in Dinoroseobacter shibae.

Koppenhöfer S, Wang H, Scharfe M, Kaever V, Wagner-Döbler I, Tomasch J.

Front Microbiol. 2019 Apr 12;10:803. doi: 10.3389/fmicb.2019.00803. eCollection 2019.

2.

Assessment of priority tobacco additives per the requirements of the EU Tobacco Products Directive (2014/40/EU): Part 1: Background, approach, and summary of findings.

Simms L, Clarke A, Paschke T, Manson A, Murphy J, Stabbert R, Esposito M, Ghosh D, Roemer E, Martinez J, Freiesleben J, Kim HK, Lindegaard T, Scharfe M, Vincze I, Vlachos P, Wigotzki D, Pollner G, Lutz R.

Regul Toxicol Pharmacol. 2019 Jun;104:84-97. doi: 10.1016/j.yrtph.2019.02.011. Epub 2019 Feb 21.

3.

Halogen-Dependent Surface Confinement Governs Selective Alkane Functionalization to Olefins.

Zichittella G, Scharfe M, Puértolas B, Paunović V, Hemberger P, Bodi A, Szentmiklósi L, López N, Pérez-Ramírez J.

Angew Chem Int Ed Engl. 2019 Apr 23;58(18):5877-5881. doi: 10.1002/anie.201811669. Epub 2019 Feb 14.

PMID:
30645015
4.

Birth, evolution, and transmission of satellite-free mammalian centromeric domains.

Nergadze SG, Piras FM, Gamba R, Corbo M, Cerutti F, McCarter JGW, Cappelletti E, Gozzo F, Harman RM, Antczak DF, Miller D, Scharfe M, Pavesi G, Raimondi E, Sullivan KF, Giulotto E.

Genome Res. 2018 Jun;28(6):789-799. doi: 10.1101/gr.231159.117. Epub 2018 Apr 30.

5.

Effect of quality and origin of technical sucrose solutions on the inclusion of colourants into the sugar crystal matrix.

Schlumbach K, Scharfe M, Flöter E.

J Sci Food Agric. 2018 Jun;98(8):2953-2963. doi: 10.1002/jsfa.8792. Epub 2018 Jan 8.

PMID:
29168562
6.

Sex differences in outcomes of primary prevention implantable cardioverter-defibrillator therapy: combined registry data from eleven European countries.

Sticherling C, Arendacka B, Svendsen JH, Wijers S, Friede T, Stockinger J, Dommasch M, Merkely B, Willems R, Lubinski A, Scharfe M, Braunschweig F, Svetlosak M, Zürn CS, Huikuri H, Flevari P, Lund-Andersen C, Schaer BA, Tuinenburg AE, Bergau L, Schmidt G, Szeplaki G, Vandenberk B, Kowalczyk E, Eick C, Juntilla J, Conen D, Zabel M; EU-CERT-ICD Investigators.

Europace. 2018 Jun 1;20(6):963-970. doi: 10.1093/europace/eux176. Erratum in: Europace. 2018 Jun 1;20(6):970.

7.

Cancer Predisposition Cascade Screening for Hereditary Breast/Ovarian Cancer and Lynch Syndromes in Switzerland: Study Protocol.

Katapodi MC, Viassolo V, Caiata-Zufferey M, Nikolaidis C, Bührer-Landolt R, Buerki N, Graffeo R, Horváth HC, Kurzeder C, Rabaglio M, Scharfe M, Urech C, Erlanger TE, Probst-Hensch N, Heinimann K, Heinzelmann-Schwarz V, Pagani O, Chappuis PO.

JMIR Res Protoc. 2017 Sep 20;6(9):e184. doi: 10.2196/resprot.8138.

8.

Divergent co-transcriptomes of different host cells infected with Toxoplasma gondii reveal cell type-specific host-parasite interactions.

Swierzy IJ, Händel U, Kaever A, Jarek M, Scharfe M, Schlüter D, Lüder CGK.

Sci Rep. 2017 Aug 3;7(1):7229. doi: 10.1038/s41598-017-07838-w.

9.

Europium Oxybromide Catalysts for Efficient Bromine Looping in Natural Gas Valorization.

Paunović V, Lin R, Scharfe M, Amrute AP, Mitchell S, Hauert R, Pérez-Ramírez J.

Angew Chem Int Ed Engl. 2017 Aug 7;56(33):9791-9795. doi: 10.1002/anie.201704406. Epub 2017 Jun 19.

PMID:
28569443
10.

A Novel Mechanism of Host-Pathogen Interaction through sRNA in Bacterial Outer Membrane Vesicles.

Koeppen K, Hampton TH, Jarek M, Scharfe M, Gerber SA, Mielcarz DW, Demers EG, Dolben EL, Hammond JH, Hogan DA, Stanton BA.

PLoS Pathog. 2016 Jun 13;12(6):e1005672. doi: 10.1371/journal.ppat.1005672. eCollection 2016 Jun.

11.

Corrigendum: Oxychlorination-Dehydrochlorination Chemistry on Bifunctional Ceria Catalysts for Intensified Vinyl Chloride Production.

Scharfe M, Lira-Parada PA, Paunović V, Moser M, Amrute AP, Pérez-Ramírez J.

Angew Chem Int Ed Engl. 2016 Apr 4;55(15):4629. doi: 10.1002/anie.201601891. No abstract available.

PMID:
27037990
12.

Oxychlorination-Dehydrochlorination Chemistry on Bifunctional Ceria Catalysts for Intensified Vinyl Chloride Production.

Scharfe M, Lira-Parada PA, Paunović V, Moser M, Amrute AP, Pérez-Ramírez J.

Angew Chem Int Ed Engl. 2016 Feb 24;55(9):3068-72. doi: 10.1002/anie.201510903. Epub 2016 Jan 28. Erratum in: Angew Chem Int Ed Engl. 2016 Apr 4;55(15):4629.

PMID:
26823027
13.

Annual dynamics of North Sea bacterioplankton: seasonal variability superimposes short-term variation.

Lucas J, Wichels A, Teeling H, Chafee M, Scharfe M, Gerdts G.

FEMS Microbiol Ecol. 2015 Sep;91(9):fiv099. doi: 10.1093/femsec/fiv099. Epub 2015 Aug 21.

PMID:
26298013
14.

Complete Sequence of Probiotic Symbioflor 2 Escherichia coli Strain G3/10 and Draft Sequences of Symbioflor 2 E. coli Strains G1/2, G4/9, G5, G6/7, and G8.

Zschüttig A, Auerbach C, Meltke S, Eichhorn C, Brandt M, Blom J, Goesmann A, Jarek M, Scharfe M, Zimmermann K, Wassenaar TM, Gunzer F.

Genome Announc. 2015 Mar 5;3(2). pii: e01330-14. doi: 10.1128/genomeA.01330-14.

15.

A functional insulator screen identifies NURF and dREAM components to be required for enhancer-blocking.

Bohla D, Herold M, Panzer I, Buxa MK, Ali T, Demmers J, Krüger M, Scharfe M, Jarek M, Bartkuhn M, Renkawitz R.

PLoS One. 2014 Sep 23;9(9):e107765. doi: 10.1371/journal.pone.0107765. eCollection 2014.

16.

Chemical probing of the human sirtuin 5 active site reveals its substrate acyl specificity and peptide-based inhibitors.

Roessler C, Nowak T, Pannek M, Gertz M, Nguyen GT, Scharfe M, Born I, Sippl W, Steegborn C, Schutkowski M.

Angew Chem Int Ed Engl. 2014 Sep 26;53(40):10728-32. doi: 10.1002/anie.201402679. Epub 2014 Aug 11.

PMID:
25111069
17.

Cyclin-dependent kinase 6 is a chromatin-bound cofactor for NF-κB-dependent gene expression.

Handschick K, Beuerlein K, Jurida L, Bartkuhn M, Müller H, Soelch J, Weber A, Dittrich-Breiholz O, Schneider H, Scharfe M, Jarek M, Stellzig J, Schmitz ML, Kracht M.

Mol Cell. 2014 Jan 23;53(2):193-208. doi: 10.1016/j.molcel.2013.12.002. Epub 2014 Jan 2. Erratum in: Mol Cell. 2014 Feb 20;53(4):682.

18.

Virtual screening of PRK1 inhibitors: ensemble docking, rescoring using binding free energy calculation and QSAR model development.

Slynko I, Scharfe M, Rumpf T, Eib J, Metzger E, Schüle R, Jung M, Sippl W.

J Chem Inf Model. 2014 Jan 27;54(1):138-50. doi: 10.1021/ci400628q. Epub 2014 Jan 8.

PMID:
24377786
19.

SUMOylation of the polycomb group protein L3MBTL2 facilitates repression of its target genes.

Stielow C, Stielow B, Finkernagel F, Scharfe M, Jarek M, Suske G.

Nucleic Acids Res. 2014 Mar;42(5):3044-58. doi: 10.1093/nar/gkt1317. Epub 2013 Dec 24.

20.

AfroDb: a select highly potent and diverse natural product library from African medicinal plants.

Ntie-Kang F, Zofou D, Babiaka SB, Meudom R, Scharfe M, Lifongo LL, Mbah JA, Mbaze LM, Sippl W, Efange SM.

PLoS One. 2013 Oct 30;8(10):e78085. doi: 10.1371/journal.pone.0078085. eCollection 2013.

21.

Characterization of the p53 cistrome--DNA binding cooperativity dissects p53's tumor suppressor functions.

Schlereth K, Heyl C, Krampitz AM, Mernberger M, Finkernagel F, Scharfe M, Jarek M, Leich E, Rosenwald A, Stiewe T.

PLoS Genet. 2013;9(8):e1003726. doi: 10.1371/journal.pgen.1003726. Epub 2013 Aug 15.

22.

CamMedNP: building the Cameroonian 3D structural natural products database for virtual screening.

Ntie-Kang F, Mbah JA, Mbaze LM, Lifongo LL, Scharfe M, Hanna JN, Cho-Ngwa F, Onguéné PA, Owono Owono LC, Megnassan E, Sippl W, Efange SM.

BMC Complement Altern Med. 2013 Apr 16;13:88. doi: 10.1186/1472-6882-13-88.

23.

A Direct in vivo RNAi screen identifies MKK4 as a key regulator of liver regeneration.

Wuestefeld T, Pesic M, Rudalska R, Dauch D, Longerich T, Kang TW, Yevsa T, Heinzmann F, Hoenicke L, Hohmeyer A, Potapova A, Rittelmeier I, Jarek M, Geffers R, Scharfe M, Klawonn F, Schirmacher P, Malek NP, Ott M, Nordheim A, Vogel A, Manns MP, Zender L.

Cell. 2013 Apr 11;153(2):389-401. doi: 10.1016/j.cell.2013.03.026.

24.

Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences.

Günther K, Rust M, Leers J, Boettger T, Scharfe M, Jarek M, Bartkuhn M, Renkawitz R.

Nucleic Acids Res. 2013 Mar 1;41(5):3010-21. doi: 10.1093/nar/gkt035. Epub 2013 Jan 29.

25.

Inhibitors of the NAD(+)-Dependent Protein Desuccinylase and Demalonylase Sirt5.

Maurer B, Rumpf T, Scharfe M, Stolfa DA, Schmitt ML, He W, Verdin E, Sippl W, Jung M.

ACS Med Chem Lett. 2012 Oct 6;3(12):1050-3. doi: 10.1021/ml3002709. eCollection 2012 Dec 13.

26.

Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion.

Adhikary T, Brandt DT, Kaddatz K, Stockert J, Naruhn S, Meissner W, Finkernagel F, Obert J, Lieber S, Scharfe M, Jarek M, Toth PM, Scheer F, Diederich WE, Reinartz S, Grosse R, Müller-Brüsselbach S, Müller R.

Oncogene. 2013 Oct 31;32(44):5241-52. doi: 10.1038/onc.2012.549. Epub 2012 Dec 3.

27.

Genome-wide localization and expression profiling establish Sp2 as a sequence-specific transcription factor regulating vitally important genes.

Terrados G, Finkernagel F, Stielow B, Sadic D, Neubert J, Herdt O, Krause M, Scharfe M, Jarek M, Suske G.

Nucleic Acids Res. 2012 Sep;40(16):7844-57. doi: 10.1093/nar/gks544. Epub 2012 Jun 7.

28.

LINT, a novel dL(3)mbt-containing complex, represses malignant brain tumour signature genes.

Meier K, Mathieu EL, Finkernagel F, Reuter LM, Scharfe M, Doehlemann G, Jarek M, Brehm A.

PLoS Genet. 2012;8(5):e1002676. doi: 10.1371/journal.pgen.1002676. Epub 2012 May 3.

29.

Recruitment of the ATP-dependent chromatin remodeler dMi-2 to the transcribed region of active heat shock genes.

Mathieu EL, Finkernagel F, Murawska M, Scharfe M, Jarek M, Brehm A.

Nucleic Acids Res. 2012 Jun;40(11):4879-91. doi: 10.1093/nar/gks178. Epub 2012 Feb 22.

30.

The Pseudomonas aeruginosa transcriptome in planktonic cultures and static biofilms using RNA sequencing.

Dötsch A, Eckweiler D, Schniederjans M, Zimmermann A, Jensen V, Scharfe M, Geffers R, Häussler S.

PLoS One. 2012;7(2):e31092. doi: 10.1371/journal.pone.0031092. Epub 2012 Feb 3.

31.

Genome sequence of the thermophilic strain Bacillus coagulans 2-6, an efficient producer of high-optical-purity L-lactic acid.

Su F, Yu B, Sun J, Ou HY, Zhao B, Wang L, Qin J, Tang H, Tao F, Jarek M, Scharfe M, Ma C, Ma Y, Xu P.

J Bacteriol. 2011 Sep;193(17):4563-4. doi: 10.1128/JB.05378-11. Epub 2011 Jun 24.

32.

Genomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor-β/δ (PPARβ/δ).

Adhikary T, Kaddatz K, Finkernagel F, Schönbauer A, Meissner W, Scharfe M, Jarek M, Blöcker H, Müller-Brüsselbach S, Müller R.

PLoS One. 2011 Jan 19;6(1):e16344. doi: 10.1371/journal.pone.0016344.

33.

Evolutionary conservation of essential and highly expressed genes in Pseudomonas aeruginosa.

Dötsch A, Klawonn F, Jarek M, Scharfe M, Blöcker H, Häussler S.

BMC Genomics. 2010 Apr 9;11:234. doi: 10.1186/1471-2164-11-234.

34.

Fast multi-core based multimodal registration of 2D cross-sections and 3D datasets.

Scharfe M, Pielot R, Schreiber F.

BMC Bioinformatics. 2010 Jan 11;11:20. doi: 10.1186/1471-2105-11-20.

35.

Haplotypes of the porcine peroxisome proliferator-activated receptor delta gene are associated with backfat thickness.

Meidtner K, Schwarzenbacher H, Scharfe M, Severitt S, Blöcker H, Fries R.

BMC Genet. 2009 Nov 30;10:76. doi: 10.1186/1471-2156-10-76.

36.

Characterization of the porcine AMPK alpha 2 catalytic subunitgene (PRKAA2): genomic structure, polymorphism detection and association study.

Lin L, Flisikowski K, Schwarzenbacher H, Scharfe M, Severitt S, Blöcker H, Fries R.

Anim Genet. 2010 Apr;41(2):203-7. doi: 10.1111/j.1365-2052.2009.01971.x. Epub 2009 Sep 29.

PMID:
19793316
37.

Unusual chemistry in the biosynthesis of the antibiotic chondrochlorens.

Rachid S, Scharfe M, Blöcker H, Weissman KJ, Müller R.

Chem Biol. 2009 Jan 30;16(1):70-81. doi: 10.1016/j.chembiol.2008.11.005.

38.

Production of the antifungal isochromanone ajudazols A and B in Chondromyces crocatus Cm c5: biosynthetic machinery and cytochrome P450 modifications.

Buntin K, Rachid S, Scharfe M, Blöcker H, Weissman KJ, Müller R.

Angew Chem Int Ed Engl. 2008;47(24):4595-9. doi: 10.1002/anie.200705569. No abstract available.

PMID:
18461592
39.

Complete genome sequence of the myxobacterium Sorangium cellulosum.

Schneiker S, Perlova O, Kaiser O, Gerth K, Alici A, Altmeyer MO, Bartels D, Bekel T, Beyer S, Bode E, Bode HB, Bolten CJ, Choudhuri JV, Doss S, Elnakady YA, Frank B, Gaigalat L, Goesmann A, Groeger C, Gross F, Jelsbak L, Jelsbak L, Kalinowski J, Kegler C, Knauber T, Konietzny S, Kopp M, Krause L, Krug D, Linke B, Mahmud T, Martinez-Arias R, McHardy AC, Merai M, Meyer F, Mormann S, Muñoz-Dorado J, Perez J, Pradella S, Rachid S, Raddatz G, Rosenau F, Rückert C, Sasse F, Scharfe M, Schuster SC, Suen G, Treuner-Lange A, Velicer GJ, Vorhölter FJ, Weissman KJ, Welch RD, Wenzel SC, Whitworth DE, Wilhelm S, Wittmann C, Blöcker H, Pühler A, Müller R.

Nat Biotechnol. 2007 Nov;25(11):1281-9. Epub 2007 Oct 28.

PMID:
17965706
40.

From genetic diversity to metabolic unity: studies on the biosynthesis of aurafurones and aurafuron-like structures in myxobacteria and streptomycetes.

Frank B, Wenzel SC, Bode HB, Scharfe M, Blöcker H, Müller R.

J Mol Biol. 2007 Nov 16;374(1):24-38. Epub 2007 Sep 11.

PMID:
17919655
41.

Sequence and characterization of the Ig heavy chain constant and partial variable region of the mouse strain 129S1.

Retter I, Chevillard C, Scharfe M, Conrad A, Hafner M, Im TH, Ludewig M, Nordsiek G, Severitt S, Thies S, Mauhar A, Blöcker H, Müller W, Riblet R.

J Immunol. 2007 Aug 15;179(4):2419-27.

42.

Spiroketal polyketide formation in Sorangium: identification and analysis of the biosynthetic gene cluster for the highly cytotoxic spirangienes.

Frank B, Knauber J, Steinmetz H, Scharfe M, Blöcker H, Beyer S, Müller R.

Chem Biol. 2007 Feb;14(2):221-33.

43.

Molecular and biochemical studies of chondramide formation-highly cytotoxic natural products from Chondromyces crocatus Cm c5.

Rachid S, Krug D, Kunze B, Kochems I, Scharfe M, Zabriskie TM, Blöcker H, Müller R.

Chem Biol. 2006 Jun;13(6):667-81.

44.

A human-horse comparative map based on equine BAC end sequences.

Leeb T, Vogl C, Zhu B, de Jong PJ, Binns MM, Chowdhary BP, Scharfe M, Jarek M, Nordsiek G, Schrader F, Blöcker H.

Genomics. 2006 Jun;87(6):772-6. Epub 2006 Apr 17.

45.

Interspecies comparison of gene structure and computational analysis of gene regulation of 17beta-hydroxysteroid dehydrogenase type 1.

Keller B, Ohnesorg T, Mindnich R, Gloeckner CJ, Breitling R, Scharfe M, Moeller G, Blöcker H, Adamski J.

Mol Cell Endocrinol. 2006 Mar 27;248(1-2):168-71. Epub 2005 Dec 7.

PMID:
16337734
46.

Genomic peculiarity of coding sequences and metabolic potential of probiotic Escherichia coli strain Nissle 1917 inferred from raw genome data.

Sun J, Gunzer F, Westendorf AM, Buer J, Scharfe M, Jarek M, Gössling F, Blöcker H, Zeng AP.

J Biotechnol. 2005 May 4;117(2):147-61.

PMID:
15823404
47.
48.

Human versus chimpanzee chromosome-wide sequence comparison and its evolutionary implication.

Sakaki Y, Watanabe H, Taylor T, Hattori M, Fujiyama A, Toyoda A, Kuroki Y, Itoh T, Saitou N, Oota S, Kim CG, Kitano T, Lehrach H, Yaspo ML, Sudbrak R, Kahla A, Reinhardt R, Kube M, Platzer M, Taenzer S, Galgoczy P, Kel A, Blöecker H, Scharfe M, Nordsiek G, Hellmann I, Khaitovich P, Pääbo S, Chen Z, Wang SY, Ren SX, Zhang XL, Zheng HJ, Zhu GF, Wang BF, Zhao GP, Tsai SF, Wu K, Liu TT, Hsiao KJ, Park HS, Lee YS, Cheong JE, Choi SH; Chimpanzee Chromosome 22 Sequencing Consortium.

Cold Spring Harb Symp Quant Biol. 2003;68:455-60. No abstract available.

PMID:
15338648
49.

DNA sequence and comparative analysis of chimpanzee chromosome 22.

Watanabe H, Fujiyama A, Hattori M, Taylor TD, Toyoda A, Kuroki Y, Noguchi H, BenKahla A, Lehrach H, Sudbrak R, Kube M, Taenzer S, Galgoczy P, Platzer M, Scharfe M, Nordsiek G, Blöcker H, Hellmann I, Khaitovich P, Pääbo S, Reinhardt R, Zheng HJ, Zhang XL, Zhu GF, Wang BF, Fu G, Ren SX, Zhao GP, Chen Z, Lee YS, Cheong JE, Choi SH, Wu KM, Liu TT, Hsiao KJ, Tsai SF, Kim CG, OOta S, Kitano T, Kohara Y, Saitou N, Park HS, Wang SY, Yaspo ML, Sakaki Y.

Nature. 2004 May 27;429(6990):382-8.

PMID:
15164055
50.

DNA sequence and analysis of human chromosome 9.

Humphray SJ, Oliver K, Hunt AR, Plumb RW, Loveland JE, Howe KL, Andrews TD, Searle S, Hunt SE, Scott CE, Jones MC, Ainscough R, Almeida JP, Ambrose KD, Ashwell RI, Babbage AK, Babbage S, Bagguley CL, Bailey J, Banerjee R, Barker DJ, Barlow KF, Bates K, Beasley H, Beasley O, Bird CP, Bray-Allen S, Brown AJ, Brown JY, Burford D, Burrill W, Burton J, Carder C, Carter NP, Chapman JC, Chen Y, Clarke G, Clark SY, Clee CM, Clegg S, Collier RE, Corby N, Crosier M, Cummings AT, Davies J, Dhami P, Dunn M, Dutta I, Dyer LW, Earthrowl ME, Faulkner L, Fleming CJ, Frankish A, Frankland JA, French L, Fricker DG, Garner P, Garnett J, Ghori J, Gilbert JG, Glison C, Grafham DV, Gribble S, Griffiths C, Griffiths-Jones S, Grocock R, Guy J, Hall RE, Hammond S, Harley JL, Harrison ES, Hart EA, Heath PD, Henderson CD, Hopkins BL, Howard PJ, Howden PJ, Huckle E, Johnson C, Johnson D, Joy AA, Kay M, Keenan S, Kershaw JK, Kimberley AM, King A, Knights A, Laird GK, Langford C, Lawlor S, Leongamornlert DA, Leversha M, Lloyd C, Lloyd DM, Lovell J, Martin S, Mashreghi-Mohammadi M, Matthews L, McLaren S, McLay KE, McMurray A, Milne S, Nickerson T, Nisbett J, Nordsiek G, Pearce AV, Peck AI, Porter KM, Pandian R, Pelan S, Phillimore B, Povey S, Ramsey Y, Rand V, Scharfe M, Sehra HK, Shownkeen R, Sims SK, Skuce CD, Smith M, Steward CA, Swarbreck D, Sycamore N, Tester J, Thorpe A, Tracey A, Tromans A, Thomas DW, Wall M, Wallis JM, West AP, Whitehead SL, Willey DL, Williams SA, Wilming L, Wray PW, Young L, Ashurst JL, Coulson A, Blöcker H, Durbin R, Sulston JE, Hubbard T, Jackson MJ, Bentley DR, Beck S, Rogers J, Dunham I.

Nature. 2004 May 27;429(6990):369-74.

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