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Items: 44


Isolation of a Diylide-Stabilized Stannylene and Germylene: Enhanced Donor Strength through Coplanar Lone Pair Alignment.

Mohapatra C, Scharf LT, Scherpf T, Mallick B, Feichtner KS, Schwarz C, Gessner VH.

Angew Chem Int Ed Engl. 2019 Mar 22. doi: 10.1002/anie.201902831. [Epub ahead of print]


Isolation of the Metalated Ylides [Ph3 P-C-CN]M (M=Li, Na, K): Influence of the Metal Ion on the Structure and Bonding Situation.

Schwarz C, Scharf LT, Scherpf T, Weismann J, Gessner VH.

Chemistry. 2019 Feb 21;25(11):2793-2802. doi: 10.1002/chem.201805421. Epub 2019 Jan 29.


A Highly Active Ylide-Functionalized Phosphine for Palladium-Catalyzed Aminations of Aryl Chlorides.

Weber P, Scherpf T, Rodstein I, Lichte D, Scharf LT, Gooßen LJ, Gessner VH.

Angew Chem Int Ed Engl. 2019 Mar 4;58(10):3203-3207. doi: 10.1002/anie.201810696. Epub 2019 Jan 2.


Ylide-Functionalized Phosphines: Strong Donor Ligands for Homogeneous Catalysis.

Scherpf T, Schwarz C, Scharf LT, Zur JA, Helbig A, Gessner VH.

Angew Chem Int Ed Engl. 2018 Sep 24;57(39):12859-12864. doi: 10.1002/anie.201805372. Epub 2018 Jun 25.


Versatile Modes of Cooperative B-H Bond Activation Reactions in Ruthenium-Carbene Complexes: Addition, Ring-Opening and Insertion.

Scharf LT, Weismann J, Feichtner KS, Lindl F, Gessner VH.

Chemistry. 2018 Mar 7;24(14):3439-3443. doi: 10.1002/chem.201800248. Epub 2018 Feb 13.


Comparison of homologous and heterologous prime-boost vaccine approaches using Modified Vaccinia Ankara and soluble protein to induce neutralizing antibodies by the human cytomegalovirus pentamer complex in mice.

Chiuppesi F, Wussow F, Scharf L, Contreras H, Gao H, Meng Z, Nguyen J, Barry PA, Bjorkman PJ, Diamond DJ.

PLoS One. 2017 Aug 16;12(8):e0183377. doi: 10.1371/journal.pone.0183377. eCollection 2017.


Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies.

Wang H, Gristick HB, Scharf L, West AP, Galimidi RP, Seaman MS, Freund NT, Nussenzweig MC, Bjorkman PJ.

Elife. 2017 May 26;6. pii: e27389. doi: 10.7554/eLife.27389.


Metalated Ylides: A New Class of Strong Donor Ligands with Unique Electronic Properties.

Scharf LT, Gessner VH.

Inorg Chem. 2017 Aug 7;56(15):8599-8607. doi: 10.1021/acs.inorgchem.7b00099. Epub 2017 Feb 27.


The Bonding Situation in Metalated Ylides.

Scharf LT, Andrada DM, Frenking G, Gessner VH.

Chemistry. 2017 Mar 28;23(18):4422-4434. doi: 10.1002/chem.201605997. Epub 2017 Mar 7.


Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.

Freund NT, Wang H, Scharf L, Nogueira L, Horwitz JA, Bar-On Y, Golijanin J, Sievers SA, Sok D, Cai H, Cesar Lorenzi JC, Halper-Stromberg A, Toth I, Piechocka-Trocha A, Gristick HB, van Gils MJ, Sanders RW, Wang LX, Seaman MS, Burton DR, Gazumyan A, Walker BD, West AP Jr, Bjorkman PJ, Nussenzweig MC.

Sci Transl Med. 2017 Jan 18;9(373). pii: eaal2144. doi: 10.1126/scitranslmed.aal2144.


Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals.

Tauriainen J, Scharf L, Frederiksen J, Naji A, Ljunggren HG, Sönnerborg A, Lund O, Reyes-Terán G, Hecht FM, Deeks SG, Betts MR, Buggert M, Karlsson AC.

Sci Rep. 2017 Jan 13;7:40354. doi: 10.1038/srep40354.


Structural basis for germline antibody recognition of HIV-1 immunogens.

Scharf L, West AP, Sievers SA, Chen C, Jiang S, Gao H, Gray MD, McGuire AT, Scheid JF, Nussenzweig MC, Stamatatos L, Bjorkman PJ.

Elife. 2016 Mar 21;5. pii: e13783. doi: 10.7554/eLife.13783.


A Highly Conserved Residue of the HIV-1 gp120 Inner Domain Is Important for Antibody-Dependent Cellular Cytotoxicity Responses Mediated by Anti-cluster A Antibodies.

Ding S, Veillette M, Coutu M, Prévost J, Scharf L, Bjorkman PJ, Ferrari G, Robinson JE, Stürzel C, Hahn BH, Sauter D, Kirchhoff F, Lewis GK, Pazgier M, Finzi A.

J Virol. 2015 Dec 4;90(4):2127-34. doi: 10.1128/JVI.02779-15. Print 2016 Feb 15.


Avoiding Anything 'Abnormal' in the Translation of 'Usually'.

Anderson H, Scharf L, Griffin A.

Value Health. 2015 Nov;18(7):A716-7. doi: 10.1016/j.jval.2015.09.2708. Epub 2015 Oct 20. No abstract available.


A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo.

Freund NT, Horwitz JA, Nogueira L, Sievers SA, Scharf L, Scheid JF, Gazumyan A, Liu C, Velinzon K, Goldenthal A, Sanders RW, Moore JP, Bjorkman PJ, Seaman MS, Walker BD, Klein F, Nussenzweig MC.

PLoS Pathog. 2015 Oct 30;11(10):e1005238. doi: 10.1371/journal.ppat.1005238. eCollection 2015 Oct.


Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env.

Scharf L, Wang H, Gao H, Chen S, McDowall AW, Bjorkman PJ.

Cell. 2015 Sep 10;162(6):1379-90. doi: 10.1016/j.cell.2015.08.035.


Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice.

Dosenovic P, von Boehmer L, Escolano A, Jardine J, Freund NT, Gitlin AD, McGuire AT, Kulp DW, Oliveira T, Scharf L, Pietzsch J, Gray MD, Cupo A, van Gils MJ, Yao KH, Liu C, Gazumyan A, Seaman MS, Björkman PJ, Sanders RW, Moore JP, Stamatatos L, Schief WR, Nussenzweig MC.

Cell. 2015 Jun 18;161(7):1505-15. doi: 10.1016/j.cell.2015.06.003.


Antibody engineering for increased potency, breadth and half-life.

Sievers SA, Scharf L, West AP Jr, Bjorkman PJ.

Curr Opin HIV AIDS. 2015 May;10(3):151-9. doi: 10.1097/COH.0000000000000148. Review.


Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike.

Scharf L, Scheid JF, Lee JH, West AP Jr, Chen C, Gao H, Gnanapragasam PN, Mares R, Seaman MS, Ward AB, Nussenzweig MC, Bjorkman PJ.

Cell Rep. 2014 May 8;7(3):785-95. doi: 10.1016/j.celrep.2014.04.001. Epub 2014 Apr 24.


Structural insights on the role of antibodies in HIV-1 vaccine and therapy.

West AP Jr, Scharf L, Scheid JF, Klein F, Bjorkman PJ, Nussenzweig MC.

Cell. 2014 Feb 13;156(4):633-48. doi: 10.1016/j.cell.2014.01.052. Review.


Crystal structure of Vδ1 T cell receptor in complex with CD1d-sulfatide shows MHC-like recognition of a self-lipid by human γδ T cells.

Luoma AM, Castro CD, Mayassi T, Bembinster LA, Bai L, Picard D, Anderson B, Scharf L, Kung JE, Sibener LV, Savage PB, Jabri B, Bendelac A, Adams EJ.

Immunity. 2013 Dec 12;39(6):1032-42. doi: 10.1016/j.immuni.2013.11.001. Epub 2013 Nov 14.


Antibodies in HIV-1 vaccine development and therapy.

Klein F, Mouquet H, Dosenovic P, Scheid JF, Scharf L, Nussenzweig MC.

Science. 2013 Sep 13;341(6151):1199-204. doi: 10.1126/science.1241144. Review.


Expression of CD1c enhances human invariant NKT cell activation by α-GalCer.

Fox LM, Miksanek J, May NA, Scharf L, Lockridge JL, Veerapen N, Besra GS, Adams EJ, Hudson AW, Gumperz JE.

Cancer Immun. 2013 May 10;13:9. Print 2013.


Computational analysis of anti-HIV-1 antibody neutralization panel data to identify potential functional epitope residues.

West AP Jr, Scharf L, Horwitz J, Klein F, Nussenzweig MC, Bjorkman PJ.

Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10598-603. doi: 10.1073/pnas.1309215110. Epub 2013 Jun 10.


Highly stereocontrolled total synthesis of β-D-mannosyl phosphomycoketide: a natural product from Mycobacterium tuberculosis.

Li NS, Scharf L, Adams EJ, Piccirilli JA.

J Org Chem. 2013 Jun 21;78(12):5970-86. doi: 10.1021/jo4006602. Epub 2013 Jun 11.


Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody.

Scharf L, West AP Jr, Gao H, Lee T, Scheid JF, Nussenzweig MC, Bjorkman PJ, Diskin R.

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6049-54. doi: 10.1073/pnas.1303682110. Epub 2013 Mar 22.


Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.

Mouquet H, Scharf L, Euler Z, Liu Y, Eden C, Scheid JF, Halper-Stromberg A, Gnanapragasam PN, Spencer DI, Seaman MS, Schuitemaker H, Feizi T, Nussenzweig MC, Bjorkman PJ.

Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):E3268-77. doi: 10.1073/pnas.1217207109. Epub 2012 Oct 30.


γδ T cell receptors recognize the non-classical major histocompatibility complex (MHC) molecule T22 via conserved anchor residues in a MHC peptide-like fashion.

Sandstrom A, Scharf L, McRae G, Hawk AJ, Meredith SC, Adams EJ.

J Biol Chem. 2012 Feb 17;287(8):6035-43. doi: 10.1074/jbc.M111.333153. Epub 2012 Jan 3.


The 2.5 Å structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation.

Scharf L, Li NS, Hawk AJ, Garzón D, Zhang T, Fox LM, Kazen AR, Shah S, Haddadian EJ, Gumperz JE, Saghatelian A, Faraldo-Gómez JD, Meredith SC, Piccirilli JA, Adams EJ.

Immunity. 2010 Dec 14;33(6):853-62. doi: 10.1016/j.immuni.2010.11.026.


Recognition of lyso-phospholipids by human natural killer T lymphocytes.

Fox LM, Cox DG, Lockridge JL, Wang X, Chen X, Scharf L, Trott DL, Ndonye RM, Veerapen N, Besra GS, Howell AR, Cook ME, Adams EJ, Hildebrand WH, Gumperz JE.

PLoS Biol. 2009 Oct;7(10):e1000228. doi: 10.1371/journal.pbio.1000228. Epub 2009 Oct 27.


Spectral correlations of fractional Brownian motion.

Øigård TA, Hanssen A, Scharf LL.

Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Sep;74(3 Pt 1):031114. Epub 2006 Sep 14.


Factors affecting parenting stress among biologically vulnerable toddlers.

Loretta Secco M, Askin D, Yu CT, Garinger J, Mulaire-Cloutier C, Scharf L, Schwartzman L, Konyk D, Feldman MA.

Issues Compr Pediatr Nurs. 2006 Jul-Sep;29(3):131-56.


Candidate gene polymorphism in cardiovascular disease: the BIP cohort.

Leshinsky-Silver E, Cheng S, Grow MA, Shoshana S, Scharf L, Lev D, Boaz M, Brunner D, Zimlichman R.

Isr Med Assoc J. 2006 Feb;8(2):103-5.


A network for recursive extraction of canonical coordinates.

Pezeshki A, Azimi-Sadjadi MR, Scharf LL.

Neural Netw. 2003 Jun-Jul;16(5-6):801-8.


Migration of di-(2-ethylhexyl) phthalate from PVC child articles into saliva and saliva simulant.

Steiner I, Scharf L, Fiala F, Washüttl J.

Food Addit Contam. 1998 Oct;15(7):812-7.


Revising nursing documentation to meet patient outcomes.

Scharf L.

Nurs Manage. 1997 Apr;28(4):38-9.


Patients', nurses', and physicians' perceptions of nurses' caring behaviors.

Scharf L, Caley L.

Nursingconnections. 1993 Spring;6(1):3-12.


Protecting patient safety in new product evaluation.

Caley LM, Scharf L.

Nurs Manage. 1992 Nov;23(11):49-50, 52-3. No abstract available.


The right to leave a hospital against medical advice.

Freer JP, Scharf LM.

N Y State J Med. 1991 Dec;91(12):554. No abstract available.


Appropriate needle disposal: implementing change to reduce injury and lessen risk.

Roberts S, Scharf L.

Am J Infect Control. 1986 Oct;14(5):32A-34A. No abstract available.


Safe needle disposal: a timely reminder.

Scharf L.

RN. 1986 Jun;49(6):42. No abstract available.


Long-term neuropsychological impact of retrolental fibroplasia: review and implications.

Scharf LS, Adams KM.

J Pediatr Psychol. 1984 Sep;9(3):303-16. Review. No abstract available.


Nursing process: one more time.

Prose GJ, Gianni N, Scharf L.

Nurs Manage. 1983 Nov;14(11):32-4. No abstract available.


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